Midtown, MO

St. Louis

Midtown
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Photo by Karissa Krull
Photo by Linda Garrison
Photo by Sophie R

Popular places to visit

Things to do


Midtown Hotel Deals

Residence Inn by Marriott St Louis Downtown
Residence Inn by Marriott St Louis Downtown
3 out of 5
525 S Jefferson Ave, St. Louis, MO
$127 nightly
The price is $151 total per night from Aug 3 to Aug 4
$151 total
Aug 3 - Aug 4
Total includes taxes and fees
Stay at this 3-star business-friendly hotel in St. Louis. Enjoy free WiFi, a 24-hour fitness center, and parking (surcharge). Our guests praise the breakfast ...
7.8/10 Good! (1,000 reviews)
"We only stayed one night while in town for the Sza concert and only in the room for a total of 5 hours, so didn’t really use a lot. Ok cleanliness and pretty much the normal older Residence Inn style. Staff was really friendly though and the room was comfortable. It was not necessarily a scary area ..."

Reviewed on Jun 29, 2025

Residence Inn by Marriott St Louis Downtown
Element St. Louis Midtown
Element St. Louis Midtown
3 out of 5
3763 Forest Park Avenue, St. Louis, MO
$135 nightly
The price is $158 total per night from Jul 20 to Jul 21
$158 total
Jul 20 - Jul 21
Total includes taxes and fees
Stay at this 3-star business-friendly hotel in St. Louis. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the breakfast and ...
9/10 Wonderful! (516 reviews)
"Valet parking was a little pricey and slow"

Reviewed on Jun 29, 2025

Element St. Louis Midtown
Hyatt Regency St. Louis at The Arch
Hyatt Regency St. Louis at The Arch
4 out of 5
315 Chestnut St, St. Louis, MO
Fully refundableReserve now, pay when you stay
$138 nightly
The price is $163 total per night from Jul 31 to Aug 1
$163 total
Jul 31 - Aug 1
Total includes taxes and fees
Stay at this 4-star business-friendly hotel in St. Louis. Enjoy free WiFi, 3 restaurants, and 2 bars/lounges. Our guests praise the helpful staff and the clean ...
8.4/10 Very Good! (3,832 reviews)
"Close to everything"

Reviewed on Jun 30, 2025

Hyatt Regency St. Louis at The Arch
The Arch Convention Hotel
The Arch Convention Hotel
3.5 out of 5
811 N 9th Street, St. Louis, MO
$115 nightly
The price is $135 total per night from Aug 3 to Aug 4
$135 total
Aug 3 - Aug 4
Total includes taxes and fees
Stay at this 3.5-star business-friendly hotel in St. Louis. Enjoy free WiFi, a 24-hour fitness center, and parking (surcharge). Our guests praise the helpful ...
7/10 Good! (1,023 reviews)
"Very comfy and quiet"

Reviewed on Jun 25, 2025

The Arch Convention Hotel
Drury Plaza Hotel St. Louis at the Arch
Drury Plaza Hotel St. Louis at the Arch
3 out of 5
2 South 4th Street, St. Louis, MO
$140 nightly
The price is $164 total per night from Jul 13 to Jul 14
$164 total
Jul 13 - Jul 14
Total includes taxes and fees
Stay at this 3-star business-friendly hotel in St. Louis. Enjoy free breakfast, free WiFi, and a fitness center. Our guests praise the breakfast and the pool ...
9.4/10 Exceptional! (2,809 reviews)
"Friendly and attentive staff. Great amenities! Perfect location."

Reviewed on Jul 1, 2025

Drury Plaza Hotel St. Louis at the Arch
Clayton Plaza Hotel & Extended Stay
Clayton Plaza Hotel & Extended Stay
3.5 out of 5
7750 Carondelet Avenue, St. Louis, MO
$100 nightly
The price is $116 total per night from Jul 20 to Jul 21
$116 total
Jul 20 - Jul 21
Total includes taxes and fees
Stay at this 3.5-star business-friendly hotel in St. Louis. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the breakfast and ...
8.8/10 Excellent! (2,912 reviews)
Fun family getaway
"Our hotel room was extremely clean. Both the shower and bath were a standout, I let my daughter take a bath in the tub- which never happens at a hotel. The king bed was super comfortable and the air conditioning made it even better. Friendly staff, always helping us with a smile."

Reviewed on Jul 1, 2025

Clayton Plaza Hotel & Extended Stay
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Other neighborhoods around Midtown

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The Gate

While there might not be top attractions in The Gate, you can explore the larger area and discover places like Busch Stadium and St. Louis Union Station.

The Gate
St. Louis which includes interior views

Downtown West

If you're spending some time in Downtown West, St. Louis Union Station and Enterprise Center are top sights worth seeing.

Downtown West
Lafayette Square which includes a house and a garden

Lafayette Square

The restaurants and shopping are a few reasons travelers visit Lafayette Square. Though there aren't many top sights in the neighborhood, you can visit St. Louis Union Station and Enterprise Center, a few notable attractions nearby.

Lafayette Square
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Shaw

4.5/5(3 area reviews)

While there might not be top attractions in Shaw, you can explore the larger area and discover places like Missouri Botanical Gardens and Arboretum and St. Louis Science Center.

Shaw
Central West End

Central West End

4.5/5(450 area reviews)

Bordering Forest Park with free cultural institutions, this St. Louis neighborhood boasts a bustling commercial district along Euclid Avenue and the world's largest mosaic collection at the Cathedral Basilica of Saint Louis.

Central West End
Not just bars but also loft apartments are lit in rainbow lights for Pride weekend in the Grove neighborhood in St. Louis! #LifeAtExpedia

The Grove

The Grove might not have many top sights, but St. Louis Zoo and St. Louis Science Center are two attractions nearby that you can check out.

The Grove


Midtown, MO

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