Midtown, MO

St. Louis

Midtown
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Photo by Karissa Krull
Photo by Linda Garrison
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Popular places to visit

Things to do


Midtown Hotel Deals

Element St. Louis Midtown

Element St. Louis Midtown

3 out of 5
3763 Forest Park Avenue, St. Louis, MO
$135 nightly
The price is $158 total per night from Oct 22 to Oct 23
$158 total
Oct 22 - Oct 23
Total with taxes and fees
Stay at this 3-star business-friendly hotel in St. Louis. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the breakfast and ...
9/10 Wonderful! (599 reviews)
"I loved this place, the staff and even the people staying there were all super friendly!!"

Reviewed on Sep 30, 2025

Element St. Louis Midtown
Residence Inn by Marriott St Louis Downtown

Residence Inn by Marriott St Louis Downtown

3 out of 5
525 S Jefferson Ave, St. Louis, MO
$114 nightly
The price is $136 total per night from Oct 12 to Oct 13
$136 total
Oct 12 - Oct 13
Total with taxes and fees
Stay at this 3-star business-friendly hotel in St. Louis. Enjoy free WiFi, a 24-hour fitness center, and parking (surcharge). Our guests praise the breakfast ...
7.8/10 Good! (1,004 reviews)
"Overall, it was great. The breakfast was good, with many options. Staff service was good; however, they should smile more and be more attentive to guests' questions, responding kindly."

Reviewed on Sep 30, 2025

Residence Inn by Marriott St Louis Downtown
Clayton Plaza Hotel & Extended Stay

Clayton Plaza Hotel & Extended Stay

3.5 out of 5
7750 Carondelet Avenue, St. Louis, MO
$102 nightly
The price is $119 total per night from Oct 19 to Oct 20
$119 total
Oct 19 - Oct 20
Total with taxes and fees
Stay at this 3.5-star business-friendly hotel in St. Louis. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the breakfast and ...
8.8/10 Excellent! (2,949 reviews)
"The breakfast is alot like other hot breakfast in hotels but you eat in the restaurant in better surroundings."

Reviewed on Oct 3, 2025

Clayton Plaza Hotel & Extended Stay
Drury Plaza Hotel St. Louis at the Arch

Drury Plaza Hotel St. Louis at the Arch

3 out of 5
2 South 4th Street, St. Louis, MO
$136 nightly
The price is $159 total per night from Oct 19 to Oct 20
$159 total
Oct 19 - Oct 20
Total with taxes and fees
Stay at this 3-star business-friendly hotel in St. Louis. Enjoy free breakfast, free WiFi, and a fitness center. Our guests praise the breakfast and the pool ...
9.4/10 Exceptional! (3,089 reviews)
"It was nearby the arch and that park. The room was in excellent condition, spacious, very grateful for the conditions, and the breakfast was wonderful, along with the coffee, the refreshments, the choices, everything was grand, even the parking in the garage was great."

Reviewed on Oct 3, 2025

Drury Plaza Hotel St. Louis at the Arch
Hyatt Regency St. Louis at The Arch

Hyatt Regency St. Louis at The Arch

4 out of 5
315 Chestnut St, St. Louis, MO
$122 nightly
The price is $144 total per night from Nov 2 to Nov 3
$144 total
Nov 2 - Nov 3
Total with taxes and fees
Stay at this 4-star business-friendly hotel in St. Louis. Enjoy free WiFi, 3 restaurants, and 2 bars/lounges. Our guests praise the helpful staff and the clean ...
8.4/10 Very Good! (4,034 reviews)
"Great location and friendly staff!"

Reviewed on Sep 29, 2025

Hyatt Regency St. Louis at The Arch
Pear Tree Inn St. Louis Airport

Pear Tree Inn St. Louis Airport

2.5 out of 5
10810 Pear Tree Ln, St. Ann, MO
$90 nightly
The price is $106 total per night from Oct 20 to Oct 21
$106 total
Oct 20 - Oct 21
Total with taxes and fees
Book a stay at this business-friendly hotel in St. Ann. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
9.2/10 Wonderful! (2,705 reviews)
"Really great!"

Reviewed on Oct 1, 2025

Pear Tree Inn St. Louis Airport
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Other neighborhoods around Midtown

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The Gate

While there might not be top attractions in The Gate, you can explore the larger area and discover places like St. Louis Union Station and Busch Stadium.

The Gate
St. Louis which includes interior views

Downtown West

If you're spending some time in Downtown West, St. Louis Union Station and St. Louis Aquarium at Union Station are top sights worth seeing.

Downtown West
Lafayette Square which includes a house and a garden

Lafayette Square

The restaurants and shopping are a few reasons travelers visit Lafayette Square. Though there aren't many top sights in the neighborhood, you can visit St. Louis Union Station and Busch Stadium, a few notable attractions nearby.

Lafayette Square
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Shaw

4.5/5(3 area reviews)

While there might not be top attractions in Shaw, you can explore the larger area and discover places like Missouri Botanical Gardens and Arboretum and St. Louis Science Center.

Shaw
Central West End

Central West End

4.5/5(450 area reviews)

Bordering Forest Park with free cultural institutions, this St. Louis neighborhood boasts a bustling commercial district along Euclid Avenue and the world's largest mosaic collection at the Cathedral Basilica of Saint Louis.

Central West End
Not just bars but also loft apartments are lit in rainbow lights for Pride weekend in the Grove neighborhood in St. Louis! #LifeAtExpedia

The Grove

The Grove might not have many top sights, but St. Louis Science Center and Missouri Botanical Gardens and Arboretum are two attractions nearby that you can check out.

The Grove


Midtown, MO

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