Texas Medical Center Vacations from $188
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Your Texas Medical Center Vacation
Texas Medical Center is calling! Whatever type of break you're organizing, you can see and experience the best of this neighborhood with a Texas Medical Center vacation package. Your trip to Texas Medical Center wouldn't be complete without a stop at top attractions nearby such as Houston Zoo, Houston Natural Science Museum and Childrens Museum of Houston. Whatever your travel plans or the size of your budget, booking a perfect Texas Medical Center vacation is quick and easy with Expedia.
The Latest Texas Medical Center Vacation Packages
Price found within the past 48 hours. Click for updated prices.
Kompose Residences Houston Cy-Fair
Save 100% on your flight
Price was $318, price is now $188 per person
$188
per person
Feb 26 - Mar 1
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to Houston (IAH)
10/10 Exceptional! (2 reviews)
Great ambiance when you enter and beey updated establishment. Cozy rooms with kitchens/microwaves which was a big plus, only thing was small shower with weird curtain I didn’t like, otherwise everything was great. Attentive housekeeping, and hotel includes breakfast and activities. Food is near and activities with free parking and it felt safe. I would book again!
Reviewed on Dec 4, 2025
Margaritaville Lake Resort, Lake Conroe/Houston
Save 100% on your flight
Price was $505, price is now $280 per person
$280
per person
Jan 17 - Jan 19
found 1 day ago
Roundtrip flight included
Chicago (CHI) to Houston (IAH)
8.2/10 Very Good! (1,006 reviews)
No free breakfast, no microwave (rediculous), very hard to find light switches for lamps, no wifii, parking far from entrance altho shuttle was helpful. Beautiful sunrise and sunset…..oh wait…God made those.
Reviewed on Dec 4, 2025
DoubleTree by Hilton Hotel & Suites Houston by the Galleria
Greater Uptown
Save 100% on your flight
Price was $694, price is now $391 per person
$391
per person
Feb 26 - Mar 1
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to Houston (IAH)
8.2/10 Very Good! (2,889 reviews)
Very nice very clean very spacious view 10/10 would recommend
Reviewed on Dec 4, 2025
The Laura Hotel, Houston Downtown, Autograph Collection
Downtown Houston
Save 100% on your flight
Price was $353, price is now $225 per person
$225
per person
Jan 17 - Jan 19
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to Houston (IAH)
9/10 Wonderful! (1,036 reviews)
Mini bar and refrigerator was very hot.
No products to sell or complimentary.
Reviewed on Nov 6, 2025
Hotel Saint Augustine
Montrose
Save 100% on your flight
Price was $840, price is now $550 per person
$550
per person
Jan 4 - Jan 8
found 1 day ago
Roundtrip flight included
Newark Liberty Intl. Airport (EWR) to Houston (IAH)
9.8/10 Exceptional! (56 reviews)
One of the most accessable hotels we have ever seen. wide doors,no furniture blocking the room areas. Outside ramps almost unnoticable. Only the pool fencing gates were too high to reach. Breakfast was very good with excellent staff.
Reviewed on Nov 19, 2025
Where to stay in Texas Medical Center
Find the best Texas Medical Center areas and neighborhoods for the activities you enjoy most. Learn more about Texas Medical Center
Downtown Houston
3 out of top 10 points of interest in this area
4.5/5(2,300 area reviews)
Largest central business district in Texas, this area boasts major league sports venues, a vibrant Theater District, and shopping options like GreenStreet. Easily navigate with public transportation options like METRORail and bus lines.
Texas Medical Center Hotel Deals
Blossom Hotel Houston, Curio Collection by Hilton
7118 Bertner Ave Houston TX
Fully refundableReserve now, pay when you stay
$123 nightly
The price is $144 total per night from Dec 15 to Dec 16
$144 total
Dec 15 - Dec 16
Total with taxes and fees
9/10 Wonderful! (3,615 reviews)
Everything about our stay was excellent.
Reviewed on Dec 3, 2025
Hilton Houston Plaza/Medical Center
6633 Travis St Houston TX
Fully refundableReserve now, pay when you stay
$94 nightly
The price is $110 total per night from Dec 28 to Dec 29
$110 total
Dec 28 - Dec 29
Total with taxes and fees
8.2/10 Very Good! (1,716 reviews)
Great
Reviewed on Dec 3, 2025
Hyatt Place Houston Medical Center
7329 FANNIN STREET Building 2 Houston TX
Fully refundableReserve now, pay when you stay
$117 nightly
The price is $137 total per night from Dec 15 to Dec 16
$137 total
Dec 15 - Dec 16
Total with taxes and fees
9/10 Wonderful! (2,156 reviews)
Everything more than i expected
Reviewed on Dec 3, 2025
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Discover the most popular places to visit in Texas Medical Center
MD Anderson Cancer Center
4.5/5(788 reviews)
Though MD Anderson Cancer Center might be what brings you to town, perhaps you'll have a chance to explore more of Houston while you are here.
Texas Children's Hospital
4.5/5(26 reviews)
Though Texas Children's Hospital might be what brings you to town, perhaps you'll have a chance to explore more of Houston while you are here.
Harris Health System - Ben Taub General Hospital
Though Harris Health System - Ben Taub General Hospital might be what brings you to town, perhaps you'll have a chance to explore more of Houston while you are here.
Things to do
Houston: Houston Botanic Garden Entry Ticket
$12
per adult
80% of travellers recommend
Houston Museum of Natural Science: Cockrell Butterfly Center
$15
per adult
100% of travellers recommend
Houston Museum of Natural Science General Admission Ticket
$25
per adult
96% of travellers recommend
Explore a world of travel with Expedia
- Houston Hotels
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- Houston Zoo
- MD Anderson Cancer Center
- Hermann Park
- Rice University
- Reckling Park
- Houston Vacations
- Rice Stadium
- Miller Outdoor Theater
- NRG Stadium
- Visit Astrodome
- James Turrell's Twilight Epiphany Skyscape
- Houston Natural Science Museum
- Houston Museum of Fine Arts
- NRG Park
- Houston Museum District Vacations
- Children's Museum of Houston
- Holocaust Museum Houston
- Cullen Sculpture Garden
- Visit Riverside Terrace
- Buffalo Soldiers National Museum
- Visit Houston Museum District
- Car rentals near Houston
- Car rentals near MD Anderson Cancer Center
- Standard Car Rentals near MD Anderson Cancer Center
- Car rentals near Houston Zoo
- Sportscar Car Rentals near Houston Zoo
- Car rentals near Hermann Park
- Car rentals near Rice University
- Pickup Car Rentals near Rice University
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- Car rentals near James Turrell's Twilight Epiphany Skyscape
- Car rentals near Houston Museum District
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- Discount Quebec Rental Cars in Houston Museum District
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- Enterprise Rental Cars in Houston Museum District
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.