Museum District Vacations from $237
Book a Hotel + Flight or Car together to unlock savings
Photo by Hazem Abdul
- Plan, book, travel with confidence
- Better togetherSave up to $1,045 when you book a flight and hotel together*
- Find the right fitWith over 300,000 hotels worldwide, it's easy to create a perfect package
- Rest easyPlan, book, and manage your trip all in one place
Your Houston Museum District Vacation
Houston Museum District is beckoning! Whatever type of break you have in mind, you can see and experience more of this neighborhood with a Houston Museum District vacation package. Start your trip to Houston Museum District by visiting nearby attractions such as Houston Zoo, Houston Natural Science Museum and Childrens Museum of Houston. Don't just dream it — turn it into a reality! Reserve your perfect Houston Museum District vacation with Expedia and get to where you're going your way.
The Latest Museum District Vacation Packages
Price found within the past 48 hours. Click for updated prices.
Kozy Houston North
Save 100% on your flight
Price was $371, price is now $237 per person
$237
per person
Mar 12 - Mar 17
found 10 hours ago
Roundtrip flight included
Atlanta (ATL) to Houston (IAH)
8.8/10 Excellent! (1,354 reviews)
Very courteous staff, clean and quiet. I stayed for nine nights and l was very comfortable.
Reviewed on Jan 5, 2026
Palace Inn Blue Edgebrook
Southeast Houston
Save 100% on your flight
Price was $523, price is now $302 per person
$302
per person
Mar 10 - Mar 15
found 11 hours ago
Roundtrip flight included
Chicago (CHI) to Houston (IAH)
9.4/10 Exceptional! (142 reviews)
Such a great place to stay! Absolutely amazing!
Reviewed on Oct 13, 2025
Rusk House Serviced Apartments
Downtown Houston
Save 100% on your flight
Price was $479, price is now $305 per person
$305
per person
Feb 7 - Feb 10
found 5 hours ago
Roundtrip flight included
Atlanta (ATL) to Houston (IAH)
9.2/10 Wonderful! (296 reviews)
Greatest experience, hotel was attentive to everything I needed, booked another night just because it was the best time!
Reviewed on Dec 25, 2025
Holiday Inn Club Vacations Galveston Beach Resort by IHG
West End
Save 100% on your flight
Price was $434, price is now $281 per person
$281
per person
Feb 18 - Feb 22
found 5 hours ago
Roundtrip flight included
Atlanta (ATL) to Houston (IAH)
8.8/10 Excellent! (1,006 reviews)
The housekeeping manager was so friendly and helpful. I’ve stayed in four different rooms with different floor plans and this was the tiniest room. We were on the fifth floor next to the elevator that was broken. But loved the heated pool and hot tub. Location is convenient being right on the beach. Overall a great hotel but I said several times I did not want to purchase a villa and was continuously called four times in about four hours. I did not have time for a three hour presentation and I had to keep repeating myself. A little frustrating.
Reviewed on Dec 25, 2025
Blossom Hotel Houston, Curio Collection by Hilton
Texas Medical Center
Save 100% on your flight
Price was $989, price is now $644 per person
$644
per person
Mar 12 - Mar 17
found 10 hours ago
Roundtrip flight included
Atlanta (ATL) to Houston (IAH)
9/10 Wonderful! (3,554 reviews)
Great stay. No complaints. Will be back.
Reviewed on Jan 6, 2026
Where to stay in Museum District
Find the best Museum District areas and neighborhoods for the activities you enjoy most. Learn more about Museum District
Downtown Houston
3 out of top 10 points of interest in this area
4.5/5(2,300 area reviews)
Largest central business district in Texas, this area boasts major league sports venues, a vibrant Theater District, and shopping options like GreenStreet. Easily navigate with public transportation options like METRORail and bus lines.
Museum District Hotel Deals
DoubleTree by Hilton Hotel & Suites Houston by the Galleria
5353 Westheimer Rd Houston TX
Fully refundableReserve now, pay when you stay
$130 nightly
The price is $152 total per night from Feb 6 to Feb 7
$152 total
Feb 6 - Feb 7
Total with taxes and fees
8.2/10 Very Good! (3,228 reviews)
Perfect as always!
Reviewed on Jan 6, 2026
Club Quarters Hotel Downtown, Houston
1085 Rusk Street Houston TX
Fully refundableReserve now, pay when you stay
$88 nightly
The price is $103 total per night from Jan 12 to Jan 13
$103 total
Jan 12 - Jan 13
Total with taxes and fees
8.4/10 Very Good! (3,994 reviews)
I travel to Houston several times in a year. First time staying at Club Quarters Hotel and it may be the best stay for an excellent price. Great service from hotel staff as well as valet, they took really good care of me. Nice view of downtown Houston, perfect spot, not far from restaurants or entertainment ...
Reviewed on Jan 6, 2026
Hilton Houston Plaza/Medical Center
6633 Travis St Houston TX
Fully refundableReserve now, pay when you stay
$94 nightly
The price is $110 total per night from Jan 11 to Jan 12
$110 total
Jan 11 - Jan 12
Total with taxes and fees
8.2/10 Very Good! (1,814 reviews)
The property was wonderful, but the staff was Exemplary. I spent about 10-12 days here on different reservations and Seymour, at the front desk, was very helpful and attentive to all of my needs. Thank you Seymour!
Reviewed on Jan 5, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Discover the most popular places to visit in Museum District
Houston Natural Science Museum
You can spend time studying the exhibits at Houston Natural Science Museum in Houston. Experience the area's acclaimed theater scene and lively festivals.
Children's Museum of Houston
You can take time to visit Children's Museum of Houston during your travels to Houston. Experience the area's lively festivals and acclaimed art scene.
Buffalo Soldiers National Museum
You can spend time browsing the exhibits at Buffalo Soldiers National Museum during your trip to Houston. Experience the fascinating museums and acclaimed theater scene in this vibrant area.
Things to do
Houston: Houston Botanic Garden Entry Ticket
$12
per adult
80% of travellers recommend
Houston Museum of Natural Science: Cockrell Butterfly Center
$15
per adult
100% of travellers recommend
Explore a world of travel with Expedia
- Houston Hotels
- Hotels near Downtown Houston
- Cheap Hotels in Houston
- Hotels near MD Anderson Cancer Center
- Hotels near Health Museum
- Hotels near Children's Museum of Houston
- Hotels near Houston Natural Science Museum
- Hotels near Miller Outdoor Theater
- B&B in Museum District Station
- Hotels near Museum District Station
- Hotels near Holocaust Museum Houston
- Hotels near Clayton Library Center for Genealogical Research
- Hotels near Houston Zoo
- Hotels near Houston Museum of Fine Arts
- Hotels near Asia Society Texas Center
- Hotels near Hermann Park
- Hotels near Buffalo Soldiers National Museum
- Hotels near Rice University
- Hotels near Czech Center Museum
- Hotels near Lawndale Art Center
- Hotels near Texas Medical Center
- Apartments in Memorial Hermann Hospital/Houston Zoo Station
- Vacation Homes in Memorial Hermann Hospital/Houston Zoo Station
- Hotels near Memorial Hermann Hospital/Houston Zoo Station
- Resorts in Memorial Hermann Hospital/Houston Zoo Station
- Condo Rentals in Memorial Hermann Hospital/Houston Zoo Station
- Hotels near NRG Stadium
- Apartments in Dryden/TMC Station
- Hotels near Dryden/TMC Station
- Aparthotels in Dryden/TMC Station
- Hotels near South Central Houston
- Gay friendly Hotels in South Central Houston
- Hotels near Riverside Terrace
- Hotels near The Chapel of St. Basil
- Hotels near Continental Club
- Hotels near University of St. Thomas
- Hotels near Reckling Park
- Hotels near Rothko Chapel
- Hotels near Cy Twombly Gallery
- Hotels near James Turrell's Twilight Epiphany Skyscape
- Hotels near Ensemble Theatre
- Hotels near Menil Collection
- Cheap Hotels in Texas Medical Center
- Hyatt Hotels in Texas Medical Center
- Pet-friendly Hotels in Texas Medical Center
- Hotels near Diverse Works
- Hotels with Kitchenettes in Texas Medical Center
- Hotels near Midtown Arts and Theater Center Houston
- Hotels near Rice Stadium
- La Quinta Inn & Suites Hotels in Texas Medical Center
- Luxury Hotels in Texas Medical Center
- 4 Star Hotels in Texas Medical Center
- 5 Star Hotels in Texas Medical Center
- Houston Zoo
- Houston Vacations
- Houston Natural Science Museum
- Children's Museum of Houston
- Houston Museum of Fine Arts
- Hermann Park
- Miller Outdoor Theater
- Holocaust Museum Houston
- Buffalo Soldiers National Museum
- Cullen Sculpture Garden
- Rice University
- MD Anderson Cancer Center
- Byzantine Chapel Fresco Museum
- Menil Collection
- The Chapel of St. Basil
- Reckling Park
- University of St. Thomas
- Cy Twombly Gallery
- James Turrell's Twilight Epiphany Skyscape
- Ensemble Theatre
- Rice Stadium
- Bering Memorial Methodist Church
- Texas Southern University
- Visit Riverside Terrace
- Midtown Vacations
- Visit Texas Medical Center
- Car rentals near Houston
- Car rentals near Children's Museum of Houston
- Car rentals near Houston Museum of Fine Arts
- Car rentals near Hermann Park
- Car rentals near Houston Zoo
- Sportscar Car Rentals near Houston Zoo
- Car rentals near Rice University
- Pickup Car Rentals near Rice University
- SUV Car Rentals near Rice University
- Van Car Rentals near Rice University
- Car rentals near MD Anderson Cancer Center
- Standard Car Rentals near MD Anderson Cancer Center
- Car rentals near South Central Houston
- Car rentals near University of St. Thomas
- Car rentals near James Turrell's Twilight Epiphany Skyscape
- Thrifty Car Rental Rental Cars in Texas Medical Center
- Car rentals near Texas Medical Center
- Enterprise Rental Cars in Texas Medical Center
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.