Title: $64 Car Rental Texas Medical Center, TX - Expedia.com [Texas Medical Center Travel Guide](https://expedia.com/Houston-Texas-Medical-Center.dx6143504)[Hotels in Texas Medical Center](https://expedia.com/Texas-Medical-Center-Houston-Hotels.0-n6143504-0.Travel-Guide-Filter-Hotels)[Flights to Houston](https://expedia.com/Cheap-Flights-To-Houston.d178265.Travel-Guide-Flights)[Things to do in Houston](https://expedia.com/Things-To-Do-In-Houston.d178265.Travel-Guide-Activities)[Texas Medical Center Vacations](https://expedia.com/Texas-Medical-Center.d6143504.Destination-Travel-Guides) ![](https://images.trvl-media.com/place/6143504/24718cb1-d944-454b-b1a9-0c611d76d414.jpg?impolicy=fcrop&w=1200&h=300&q=medium) # $64 Car Rental Texas Medical Center, TX ## Search and Compare from Car Companies in Texas Medical Center ## Featured car rental suppliers Compare from agencies ![car suppliers logo](https://forever.travel-assets.com/flex/flexmanager/images/2022/02/16/car-suppliers-logo-desktop.jpg) ## Top Car Deals in Texas Medical Center \* Price found within the past 6 days. Click for updated prices. Tue, Mar 10 - Wed, Mar 11 ### Midsize Nissan Sentra, Toyota Corolla, Honda Civic or similar - 5 people - Unlimited mileage ![U-Save](//mediaim.expedia.com/cars/logos/SV.png) Houston, Texas, USA ![Nissan Sentra, Toyota Corolla, Honda Civic](//mediaim.expedia.com/cars/34/8022344d-d633-4a4b-a4fc-3a3c35968e25.jpg) #### $78 includes taxes & fees $23 per day found 6 hours ago [](https://expedia.com/carsearch?paandi=true&fdrp=1&styp=2&dagv=1&subm=1&olat=29.942600&olon=-95.306180&date1=3/10/2026&date2=3/11/2026&pprfrr=22.8&tprfrr=78.17&cvrfrr=SV&ctrfrr=ID&crfrr=pricefeedResponseFlex&SearchType=Place&selCC=[%22midsize%22]) Tue, Mar 10 - Wed, Mar 11 ### Fullsize Honda Accord, Nissan Altima, Acura Integra or similar - 5 people - Unlimited mileage ![U-Save](//mediaim.expedia.com/cars/logos/SV.png) Houston, Texas, USA ![Honda Accord, Nissan Altima, Acura Integra](//mediaim.expedia.com/cars/34/7fab4df9-981d-43f1-bf58-5d6d687c9bef.jpg) #### $79 includes taxes & fees $23 per day found 6 hours ago [](https://expedia.com/carsearch?paandi=true&fdrp=1&styp=2&dagv=1&subm=1&olat=29.942600&olon=-95.306180&date1=3/10/2026&date2=3/11/2026&pprfrr=23.1&tprfrr=78.97&cvrfrr=SV&ctrfrr=FC&crfrr=pricefeedResponseFlex&SearchType=Place&selCC=[%22fullsize%22]) Tue, Mar 10 - Wed, Mar 11 ### Economy Chevrolet Spark or similar - 4 people - Unlimited mileage ![Rent-A-Wreck](//mediaim.expedia.com/cars/logos/RW.png) Humble, Texas, USA ![Chevrolet Spark](//mediaim.expedia.com/cars/33/c30eeecb-be9e-4673-9115-f344a075169d.jpg) #### $64 includes taxes & fees $27 per day found 6 hours ago [](https://expedia.com/carsearch?paandi=true&fdrp=1&styp=2&dagv=1&subm=1&olat=29.983750&olon=-95.287230&date1=3/10/2026&date2=3/11/2026&pprfrr=27.27&tprfrr=64.37&cvrfrr=RW&ctrfrr=EC&crfrr=pricefeedResponseFlex&SearchType=Place&selCC=[%22economy%22]) Fri, Mar 6 - Sat, Mar 7 ### Special Wild Card Compact or larger if available or similar - 5 people - Unlimited mileage ![Thrifty](//mediaim.expedia.com/cars/logos/ZT.png) Houston, Texas, USA ![Wild Card Compact or larger if available](//mediaim.expedia.com/cars/45/c51b48dd-8870-4d51-8c96-7f12f1215074.jpg) #### $95 includes taxes & fees $47 per day found 8 hours ago [](https://expedia.com/carsearch?paandi=true&fdrp=1&styp=2&dagv=1&subm=1&olat=29.983330&olon=-95.333320&date1=3/6/2026&date2=3/7/2026&pprfrr=47.14&tprfrr=94.75&cvrfrr=ZT&ctrfrr=XX&crfrr=pricefeedResponseFlex&SearchType=Place&selCC=[%22other%22]) Fri, Mar 6 - Sat, Mar 7 ### Compact Ford Focus or similar - 5 people - Unlimited mileage ![Hertz](//mediaim.expedia.com/cars/logos/ZE.png) Houston, Texas, USA ![Ford Focus](//mediaim.expedia.com/cars/40/b0b0d176-5217-4b23-9e8d-d49ee10835ec.jpg) #### $75 includes taxes & fees $49 per day found 8 hours ago [](https://expedia.com/carsearch?paandi=true&fdrp=1&styp=2&dagv=1&subm=1&olat=29.983330&olon=-95.333320&date1=3/6/2026&date2=3/7/2026&pprfrr=48.79&tprfrr=74.91&cvrfrr=ZE&ctrfrr=CC&crfrr=pricefeedResponseFlex&SearchType=Place&selCC=[%22compact%22]) Fri, Mar 6 - Sat, Mar 7 ### Standard Chevrolet Cruze or similar - 5 people - Unlimited mileage ![Dollar](//mediaim.expedia.com/cars/logos/ZR.png) Houston, Texas, USA ![Chevrolet Cruze](//mediaim.expedia.com/cars/43/428f5fd5-c16a-45ea-83fa-3c6a0e647b4c.jpg) #### $100 includes taxes & fees $51 per day found 8 hours ago [](https://expedia.com/carsearch?paandi=true&fdrp=1&styp=2&dagv=1&subm=1&olat=29.983330&olon=-95.333320&date1=3/6/2026&date2=3/7/2026&pprfrr=50.79&tprfrr=100.5&cvrfrr=ZR&ctrfrr=SC&crfrr=pricefeedResponseFlex&SearchType=Place&selCC=[%22standard%22]) Sun, Mar 8 - Mon, Mar 9 ### Premium Pickup Regular Cab Ford F150 or similar - 5 people - Unlimited mileage ![Alamo](//mediaim.expedia.com/cars/logos/AL.png) Houston, Texas, USA ![Ford F150](//mediaim.expedia.com/cars/6/a9d17556-0fbf-437d-906c-b0f1dd727f74.jpg) #### $130 includes taxes & fees $60 per day found 5 hours ago [](https://expedia.com/carsearch?paandi=true&fdrp=1&styp=2&dagv=1&subm=1&olat=29.969580&olon=-95.332200&date1=3/8/2026&date2=3/9/2026&pprfrr=60.00&tprfrr=130.17&cvrfrr=AL&ctrfrr=PP&crfrr=pricefeedResponseFlex&SearchType=Place&selCC=[%22pickup%22]) Fri, Mar 6 - Sat, Mar 7 ### Standard Elite Special Ford Mustang Mach-E or similar - 5 people - Unlimited mileage ![Payless](//mediaim.expedia.com/cars/logos/ZA.png) Houston, Texas, USA ![Ford Mustang Mach-E](//mediaim.expedia.com/cars/38/95f0c215-36ef-4ab3-b992-e75035169054.jpg) #### $94 includes taxes & fees $63 per day found 8 hours ago [](https://expedia.com/carsearch?paandi=true&fdrp=1&styp=2&dagv=1&subm=1&olat=29.969493&olon=-95.335488&date1=3/6/2026&date2=3/7/2026&pprfrr=62.99&tprfrr=94.21&cvrfrr=ZA&ctrfrr=RX&crfrr=pricefeedResponseFlex&SearchType=Place&selCC=[%22standard%22]) Fri, Mar 6 - Sat, Mar 7 ### Midsize Elite Special Tesla Model 3 or similar - 5 people - Unlimited mileage ![Payless](//mediaim.expedia.com/cars/logos/ZA.png) Houston, Texas, USA ![Tesla Model 3](//mediaim.expedia.com/cars/38/68d85d23-5a58-4efc-9d6a-25d8f8971048.jpg) #### $104 includes taxes & fees $71 per day found 8 hours ago [](https://expedia.com/carsearch?paandi=true&fdrp=1&styp=2&dagv=1&subm=1&olat=29.969493&olon=-95.335488&date1=3/6/2026&date2=3/7/2026&pprfrr=70.99&tprfrr=104.43&cvrfrr=ZA&ctrfrr=JX&crfrr=pricefeedResponseFlex&SearchType=Place&selCC=[%22midsize%22]) Fri, Mar 6 - Sat, Mar 7 ### Mini Van Chrysler Pacifica or similar - 7 people - Unlimited mileage ![Enterprise](//mediaim.expedia.com/cars/logos/ET.png) Houston, Texas, USA ![Chrysler Pacifica](//mediaim.expedia.com/cars/15/fcc6db92-d9d2-4f94-8470-36aec1bd49c1.jpg) #### $119 includes taxes & fees $81 per day found 8 hours ago [](https://expedia.com/carsearch?paandi=true&fdrp=1&styp=2&dagv=1&subm=1&olat=29.970060&olon=-95.335470&date1=3/6/2026&date2=3/7/2026&pprfrr=80.85&tprfrr=119.25&cvrfrr=ET&ctrfrr=MV&crfrr=pricefeedResponseFlex&SearchType=Place&selCC=[%22minivan%22]) Fri, Mar 6 - Sat, Mar 7 ### Fullsize Elite Pickup Regular Cab Ram 2500 Crew or similar - 5 people - Unlimited mileage ![Thrifty](//mediaim.expedia.com/cars/logos/ZT.png) Houston, Texas, USA ![Ram 2500 Crew](//mediaim.expedia.com/cars/45/b3514c8b-f726-43d3-99fe-35c382ed1003.jpg) #### $134 includes taxes & fees $90 per day found 8 hours ago [](https://expedia.com/carsearch?paandi=true&fdrp=1&styp=2&dagv=1&subm=1&olat=29.983330&olon=-95.333320&date1=3/6/2026&date2=3/7/2026&pprfrr=89.54&tprfrr=133.88&cvrfrr=ZT&ctrfrr=GP&crfrr=pricefeedResponseFlex&SearchType=Place&selCC=[%22pickup%22]) Sun, Mar 8 - Mon, Mar 9 ### Luxury Audi A4 or BMW 3 Series or similar - 5 people - Unlimited mileage ![Alamo](//mediaim.expedia.com/cars/logos/AL.png) Houston, Texas, USA ![Audi A4 or BMW 3 Series](//mediaim.expedia.com/cars/6/e34fcad5-de08-479b-bf77-4b93fbde6fd0.jpg) #### $186 includes taxes & fees $91 per day found 5 hours ago [](https://expedia.com/carsearch?paandi=true&fdrp=1&styp=2&dagv=1&subm=1&olat=29.969580&olon=-95.332200&date1=3/8/2026&date2=3/9/2026&pprfrr=91.04&tprfrr=185.7&cvrfrr=AL&ctrfrr=LC&crfrr=pricefeedResponseFlex&SearchType=Place&selCC=[%22luxury%22]) Fri, Mar 6 - Sat, Mar 7 ### Luxury Elite Genesis G80E or similar - 5 people - Unlimited mileage ![Payless](//mediaim.expedia.com/cars/logos/ZA.png) Houston, Texas, USA ![Genesis G80E](//mediaim.expedia.com/cars/38/8f159325-6b72-41d1-b84d-a32c367421b1.jpg) #### $131 includes taxes & fees $92 per day found 8 hours ago [](https://expedia.com/carsearch?paandi=true&fdrp=1&styp=2&dagv=1&subm=1&olat=29.969493&olon=-95.335488&date1=3/6/2026&date2=3/7/2026&pprfrr=91.99&tprfrr=131.26&cvrfrr=ZA&ctrfrr=WC&crfrr=pricefeedResponseFlex&SearchType=Place&selCC=[%22luxury%22]) Fri, Mar 6 - Sat, Mar 7 ### Premium Elite SUV Audi Q5 or similar - 5 people - Unlimited mileage ![Alamo](//mediaim.expedia.com/cars/logos/AL.png) Houston, Texas, USA ![Audi Q5](//mediaim.expedia.com/cars/6/658a9a7e-ff8a-4887-b1d5-b9226b351acc.jpg) #### $171 includes taxes & fees $122 per day found 8 hours ago [](https://expedia.com/carsearch?paandi=true&fdrp=1&styp=2&dagv=1&subm=1&olat=29.969580&olon=-95.332200&date1=3/6/2026&date2=3/7/2026&pprfrr=121.71&tprfrr=171.46&cvrfrr=AL&ctrfrr=UF&crfrr=pricefeedResponseFlex&SearchType=Place&selCC=[%22suv%22]) ### Don't see what you're looking for? See all car rentals in Texas Medical Center [View all cars](https://expedia.com/carsearch?paandi=true&fdrp=1&styp=2&dagv=1&subm=1&locn=Texas%20Medical%20Center,%20Houston,%20Texas,%20United%20States%20of%20America&dpln=6143504&date1=3/11/2026&date2=3/13/2026&crfrr=defaultFlex&SearchType=Place) Lowest prices found within the past 6 hours. Prices and availability subject to change. Additional terms may apply. ![](https://forever.travel-assets.com/flex/flexmanager/images/2026/02/06/expedia-sale-2026-desktop-us-ca.jpg?impolicy=fcrop&w=1400&h=600&q=mediumHigh) ## The Annual Vacation Sale Members save up to 40% on hotels and homes. Plan this year’s big trip and save. [Book now](https://expedia.com/deals?rfrr=CTG_SPRING_PROMO_6143504) ## Frequently asked questions ### How much is a rental car per day in Texas Medical Center? ### What happens if I need to cancel my Texas Medical Center car reservation? ### Where can I go on a road trip from Texas Medical Center? > - You'll discover Kyle Field and countless other interesting sights in College Station. From Texas Medical Center, it's roughly 85 miles away. > - Next stop? Galveston, which is around 45 miles away. Moody Gardens is one local draw card you shouldn't miss. > - Visit Lady Bird Johnson Wildflower Center to discover some local nature. Pack a picnic to enjoy or just chill out in the fresh air. From Texas Medical Center, it's around 150 miles away. ### How do I find the best car rental deals in Texas Medical Center with Expedia? ### How old do you have to be to rent a car in Texas Medical Center? ### What do you need to rent a car in Texas Medical Center? ### What is the cheapest car rental in Texas Medical Center? ### Can I rent a car for a month or longer in Texas Medical Center? ### Where can I find a Texas Medical Center car rental if I am younger than 25? ### What insurance should I choose for my car rental in Texas Medical Center? ## Car Rental Information | Popular car types | [SUV](https://www.expedia.com/lp/b/car-rental/suv?rfrr=car.table.SUV), [Full Size](https://www.expedia.com/lp/b/car-rental/fullsize?rfrr=car.table.FullSize), [Economy](https://www.expedia.com/lp/b/car-rental/economy?rfrr=car.table.Economy) | | ------------------------------------------------ | ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- | | Car suppliers available | | | Our best deal of the day | $64 | | Our second best deal of the day | $75 | | Our third best deal of the day | $78 | | From the airport to your hotel | [Airport Transportation](https://www.expedia.com/ground-transfers?rfrr=car.table.AirportTransportation) | | From popular domestic and international airports | [Airport Car Rentals](https://www.expedia.com/lp/b/car-rental/airport) | ## Explore a world of travel with Expedia - 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