Texas Medical Center Vacations from $155
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Your Texas Medical Center Vacation
Texas Medical Center is calling! Whatever type of break you're organizing, you can see and experience the best of this neighborhood with a Texas Medical Center vacation package. Your trip to Texas Medical Center wouldn't be complete without a stop at top attractions nearby such as Houston Zoo, Houston Natural Science Museum and Childrens Museum of Houston. Whatever your travel plans or the size of your budget, booking a perfect Texas Medical Center vacation is quick and easy with Expedia.
The Latest Texas Medical Center Vacation Packages
Price found within the past 48 hours. Click for updated prices.
DoubleTree by Hilton Hotel & Suites Houston by the Galleria
Greater Uptown
Save 100% on your flight
Price was $245, price is now $155 per person
$155
per person
Jan 9 - Jan 11
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to Houston (IAH)
8.2/10 Very Good! (2,684 reviews)
Valet system clogged up the parking garage, cars waiting down the street, blocking people from entering who want to park for themselves. Outlet hanging out of the wall and TV directory not working, engineer just shrugged and said "Sorry". Hair dryer was covered in brown, sticky substance and the replacement they gave us had half the functions broken. Pool was full of leaves. Hotel and room were very nice and clean, and the market with quick food was really nice and convenient. Nice staff but understaffed, they need more support. Overall an okay stay, but expect more from a Hilton.
Reviewed on Nov 4, 2025
Holiday Inn Houston Downtown by IHG
Downtown Houston
Save 100% on your flight
Price was $339, price is now $208 per person
$208
per person
Jan 9 - Jan 11
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to Houston (IAH)
8.8/10 Excellent! (1,481 reviews)
The breakfast was great every time. The shuttle (Nancy!) was an awesome perk and super useful to get around. The room was clean and everyone was super helpful.
Reviewed on Nov 4, 2025
The Lancaster Hotel
Downtown Houston
Save 100% on your flight
Price was $1,134, price is now $744 per person
$744
per person
Jan 23 - Jan 26
found 20 hours ago
Roundtrip flight included
Boston (BOS) to Houston (IAH)
9.8/10 Exceptional! (1,011 reviews)
Stayed here for our wedding anniversary and the stay was wonderful. Loved the location in the theater district and there are a number of 24 garages around the area if you don’t want to valet. This one comes with a wholehearted recommendation
Reviewed on Nov 4, 2025
Where to stay in Texas Medical Center
Find the best Texas Medical Center areas and neighborhoods for the activities you enjoy most. Learn more about Texas Medical Center
Downtown Houston
3 out of top 10 points of interest in this area
4.5/5(2,300 area reviews)
Largest central business district in Texas, this area boasts major league sports venues, a vibrant Theater District, and shopping options like GreenStreet. Easily navigate with public transportation options like METRORail and bus lines.
Texas Medical Center Hotel Deals
Blossom Hotel Houston, Curio Collection by Hilton
7118 Bertner Ave, Houston, TX
Fully refundableReserve now, pay when you stay
$139 nightly
The price is $162 total per night from Dec 4 to Dec 5
$162 total
Dec 4 - Dec 5
Total with taxes and fees
9/10 Wonderful! (3,600 reviews)
This hotel was absolutely beautiful. The room, beds, and bathroom were perfect! I enjoyed having the valet parking and the many other amenities. I would highly recommend this hotel. This will be the hotel we use while in town for a Texan game.
Reviewed on Oct 31, 2025
Hyatt Place Houston Medical Center
7329 FANNIN STREET Building 2, Houston, TX
Fully refundableReserve now, pay when you stay
$119 nightly
The price is $139 total per night from Nov 23 to Nov 24
$139 total
Nov 23 - Nov 24
Total with taxes and fees
9/10 Wonderful! (2,086 reviews)
Quick
Reviewed on Nov 2, 2025
Hilton Houston Plaza/Medical Center
6633 Travis St, Houston, TX
Fully refundableReserve now, pay when you stay
$89 nightly
The price is $105 total per night from Nov 9 to Nov 10
$105 total
Nov 9 - Nov 10
Total with taxes and fees
8.2/10 Very Good! (1,639 reviews)
I didn't eat at hotel . Had a great stay . Comfortable and clean
Reviewed on Oct 28, 2025
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Discover the most popular places to visit in Texas Medical Center
MD Anderson Cancer Center
4.5/5(788 reviews)
Though MD Anderson Cancer Center might be what brings you to town, perhaps you'll have a chance to explore more of Houston while you are here.
Texas Children's Hospital
4.5/5(26 reviews)
Though Texas Children's Hospital might be what brings you to town, perhaps you'll have a chance to explore more of Houston while you are here.
Harris Health System - Ben Taub General Hospital
Though Harris Health System - Ben Taub General Hospital might be what brings you to town, perhaps you'll have a chance to explore more of Houston while you are here.
Things to do
Houston: Houston Botanic Garden Entry Ticket
$12
per adult
80% of travellers recommend
Houston Museum of Natural Science General Admission Ticket
$25
per adult
96% of travellers recommend
Astroville Tunnel Tour of Downtown Houston (Air-Conditioned)
$25
per adult
100% of travellers recommend
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- Houston Zoo
- MD Anderson Cancer Center
- Hermann Park
- Rice University
- Reckling Park
- Houston Vacations
- Rice Stadium
- Miller Outdoor Theater
- NRG Stadium
- Visit Astrodome
- James Turrell's Twilight Epiphany Skyscape
- Houston Natural Science Museum
- Houston Museum of Fine Arts
- NRG Park
- Houston Museum District Vacations
- Children's Museum of Houston
- Holocaust Museum Houston
- Cullen Sculpture Garden
- Visit Riverside Terrace
- Buffalo Soldiers National Museum
- Visit Houston Museum District
- Car rentals near Houston
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* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.