Texas Medical Center Vacations from $255
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Your Texas Medical Center Vacation
Texas Medical Center is calling! Whatever type of break you're organizing, you can see and experience the best of this neighborhood with a Texas Medical Center vacation package. Your trip to Texas Medical Center wouldn't be complete without a stop at top attractions nearby such as Houston Zoo, Houston Natural Science Museum and Childrens Museum of Houston. Whatever your travel plans or the size of your budget, booking a perfect Texas Medical Center vacation is quick and easy with Expedia.
The Latest Texas Medical Center Vacation Packages
Price found within the past 48 hours. Click for updated prices.
DoubleTree by Hilton Hotel & Suites Houston by the Galleria
Greater Uptown
Save 100% on your flight
Price was $389, price is now $255 per person
$255
per person
Nov 6 - Nov 9
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to Houston (IAH)
8.2/10 Very Good! (2,472 reviews)
Reserved a room and paid the fee to hold room and still was given a different room
Reviewed on Sep 16, 2025
Margaritaville Lake Resort, Lake Conroe/Houston
Save 100% on your flight
Price was $644, price is now $413 per person
$413
per person
Nov 1 - Nov 4
found 21 hours ago
Roundtrip flight included
Atlanta (ATL) to Houston (IAH)
8.2/10 Very Good! (1,014 reviews)
Rooms were spacious and clean. Too many spiders in the rooms. We were a large group and everyone was killing spiders in their room. Property was nice, pools were nice.
Reviewed on Sep 16, 2025
Moody Gardens Hotel, Spa and Convention Center
Near West End
Save 100% on your flight
Price was $598, price is now $387 per person
$387
per person
Nov 1 - Nov 4
found 21 hours ago
Roundtrip flight included
Atlanta (ATL) to Houston (IAH)
8.8/10 Excellent! (1,874 reviews)
This was my first time staying at Moody Gardens and it certainly won't be my last. The staff, property and amenities were all perfect!!
Reviewed on Sep 15, 2025
Hotel Saint Augustine
Montrose
Save 100% on your flight
Price was $628, price is now $418 per person
$418
per person
Oct 17 - Oct 19
found 13 hours ago
Roundtrip flight included
Atlanta (ATL) to Houston (IAH)
9.8/10 Exceptional! (32 reviews)
Very unique property very quaint, private beautiful grounds, convenient to a lot of museums and restaurants
Reviewed on Sep 1, 2025
Club Quarters Hotel Downtown, Houston
Downtown Houston
Save 100% on your flight
Price was $927, price is now $670 per person
$670
per person
Nov 6 - Nov 9
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to Houston (IAH)
8.4/10 Very Good! (3,634 reviews)
Shampoo was filled with water
Reviewed on Sep 16, 2025
Where to stay in Texas Medical Center
Find the best Texas Medical Center areas and neighborhoods for the activities you enjoy most. Learn more about Texas Medical Center
Downtown Houston
3 out of top 10 points of interest in this area
4.5/5(2,300 area reviews)
Largest central business district in Texas, this area boasts major league sports venues, a vibrant Theater District, and shopping options like GreenStreet. Easily navigate with public transportation options like METRORail and bus lines.
Texas Medical Center Hotel Deals
Blossom Hotel Houston
7118 Bertner Ave, Houston, TX
Fully refundableReserve now, pay when you stay
$140 nightly
The price is $164 total per night from Sep 21 to Sep 22
$164 total
Sep 21 - Sep 22
Total with taxes and fees
9/10 Wonderful! (3,504 reviews)
"Really not close to anything. But the beauty and staff make up for that. One of the most brilliant hotels I have ever stayed in, the rooms were huge. Staff was so polite and helpful. Restaurant was good. 10/10"
Reviewed on Sep 16, 2025
Hyatt Place Houston Medical Center
7329 FANNIN STREET Building 2, Houston, TX
Fully refundableReserve now, pay when you stay
$140 nightly
The price is $163 total per night from Sep 17 to Sep 18
$163 total
Sep 17 - Sep 18
Total with taxes and fees
9/10 Wonderful! (1,977 reviews)
"I had a lot of fun with the bartending staff. Everyone was nice and helpful also."
Reviewed on Sep 16, 2025
Hilton Houston Plaza/Medical Center
6633 Travis St, Houston, TX
Fully refundableReserve now, pay when you stay
$111 nightly
The price is $129 total per night from Oct 5 to Oct 6
$129 total
Oct 5 - Oct 6
Total with taxes and fees
8.2/10 Very Good! (1,581 reviews)
"Double charged for self overnight parking during check out was told by worker the $20 would be charged to room once leaving the property had to pay $20 to get out so they need to change parking garage sign to $40 for overnight self parking if that's what they charging"
Reviewed on Sep 15, 2025
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Discover the most popular places to visit in Texas Medical Center
MD Anderson Cancer Center
4.5/5(788 reviews)
Though MD Anderson Cancer Center might be what brings you to town, perhaps you'll have a chance to explore more of Houston while you are here.
Texas Children's Hospital
4.5/5(26 reviews)
Though Texas Children's Hospital might be what brings you to town, perhaps you'll have a chance to explore more of Houston while you are here.
Harris Health System - Ben Taub General Hospital
Though Harris Health System - Ben Taub General Hospital might be what brings you to town, perhaps you'll have a chance to explore more of Houston while you are here.
Things to do
Houston: Houston Botanic Garden Entry Ticket
$12
per adult
80% of travellers recommend
Houston Museum of Natural Science General Admission Ticket
$25
per adult
98% of travellers recommend
Explore a world of travel with Expedia
Explore a world of travel with Expedia
- Houston Hotels
- Hotels near MD Anderson Cancer Center
- Hotels near Downtown Houston
- Hotels near NRG Stadium
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- Apartments in Dryden/TMC Station
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- Hotels near Reckling Park
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- Adults Only Resorts & in Houston Museum District
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- Houston Zoo
- MD Anderson Cancer Center
- Hermann Park
- Rice University
- Reckling Park
- Houston Vacations
- Rice Stadium
- Miller Outdoor Theater
- NRG Stadium
- Visit Astrodome
- James Turrell's Twilight Epiphany Skyscape
- Houston Natural Science Museum
- Houston Museum of Fine Arts
- NRG Park
- Houston Museum District Vacations
- Children's Museum of Houston
- Holocaust Museum Houston
- Cullen Sculpture Garden
- Visit Riverside Terrace
- Buffalo Soldiers National Museum
- Visit Houston Museum District
- Car rentals near Houston
- Car rentals near MD Anderson Cancer Center
- Standard Car Rentals near MD Anderson Cancer Center
- Car rentals near Houston Zoo
- Sportscar Car Rentals near Houston Zoo
- Car rentals near Hermann Park
- Car rentals near Rice University
- Pickup Car Rentals near Rice University
- SUV Car Rentals near Rice University
- Van Car Rentals near Rice University
- Car rentals near James Turrell's Twilight Epiphany Skyscape
- Car rentals near Houston Museum District
- Thrifty Car Rental Rental Cars in Houston Museum District
- Hertz Rental Cars in Houston Museum District
- Alamo Rent A Car Rental Cars in Houston Museum District
- Pickup Car Rentals in Houston Museum District
- Sixt Rental Cars in Houston Museum District
- Discount Quebec Rental Cars in Houston Museum District
- Budget Rental Cars in Houston Museum District
- Enterprise Rental Cars in Houston Museum District
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.
