Texas Medical Center Vacations from $186
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Your Texas Medical Center Vacation
Texas Medical Center is calling! Whatever type of break you're organizing, you can see and experience the best of this neighborhood with a Texas Medical Center vacation package. Your trip to Texas Medical Center wouldn't be complete without a stop at top attractions nearby such as Houston Zoo, Houston Natural Science Museum and Childrens Museum of Houston. Whatever your travel plans or the size of your budget, booking a perfect Texas Medical Center vacation is quick and easy with Expedia.
The Latest Texas Medical Center Vacation Packages
Price found within the past 48 hours. Click for updated prices.
Margaritaville Lake Resort, Lake Conroe/Houston
Save 100% on your flight
Price was $540, price is now $307 per person
$307
per person
Jan 16 - Jan 18
found 1 day ago
Roundtrip flight included
Chicago (CHI) to Houston (IAH)
8.2/10 Very Good! (1,006 reviews)
No free breakfast, no microwave (rediculous), very hard to find light switches for lamps, no wifii, parking far from entrance altho shuttle was helpful. Beautiful sunrise and sunset…..oh wait…God made those.
Reviewed on Dec 4, 2025
Hotel Granduca Houston
The Galleria
Save 100% on your flight
Price was $1,288, price is now $896 per person
$896
per person
Feb 13 - Feb 17
found 7 hours ago
Roundtrip flight included
Atlanta (ATL) to Houston (IAH)
9.2/10 Wonderful! (1,002 reviews)
yes the we were there only one night the bathroom should have more towels in general and add tissues .also the a/c did not really work correctly . If we were there for any length of time. wewould have ask to correct these .
Reviewed on Nov 25, 2025
La Quinta Inn & Suites by Wyndham Galveston North at I-45
Near West End
Save 100% on your flight
Price was $565, price is now $393 per person
$393
per person
Feb 14 - Feb 21
found 22 hours ago
Roundtrip flight included
Chicago (ORD) to Houston (IAH)
8.2/10 Very Good! (1,088 reviews)
When taking a cruise from the Port of Galveston, we stay at this hotel. It’s easily the best cruise parking we’ve had. We’re on our 20th cruise and love the convenience, staff and breakfast. Our rooms are always clean and ready for us when we drive from OKC.
Reviewed on Dec 3, 2025
Where to stay in Texas Medical Center
Find the best Texas Medical Center areas and neighborhoods for the activities you enjoy most. Learn more about Texas Medical Center
Downtown Houston
3 out of top 10 points of interest in this area
4.5/5(2,300 area reviews)
Largest central business district in Texas, this area boasts major league sports venues, a vibrant Theater District, and shopping options like GreenStreet. Easily navigate with public transportation options like METRORail and bus lines.
Texas Medical Center Hotel Deals
Blossom Hotel Houston, Curio Collection by Hilton
7118 Bertner Ave Houston TX
Fully refundableReserve now, pay when you stay
$123 nightly
The price is $144 total per night from Dec 15 to Dec 16
$144 total
Dec 15 - Dec 16
Total with taxes and fees
9/10 Wonderful! (3,615 reviews)
Everything about our stay was excellent.
Reviewed on Dec 3, 2025
Hilton Houston Plaza/Medical Center
6633 Travis St Houston TX
Fully refundableReserve now, pay when you stay
$94 nightly
The price is $110 total per night from Dec 28 to Dec 29
$110 total
Dec 28 - Dec 29
Total with taxes and fees
8.2/10 Very Good! (1,716 reviews)
Great
Reviewed on Dec 3, 2025
Hyatt Place Houston Medical Center
7329 FANNIN STREET Building 2 Houston TX
Fully refundableReserve now, pay when you stay
$117 nightly
The price is $136 total per night from Dec 10 to Dec 11
$136 total
Dec 10 - Dec 11
Total with taxes and fees
9/10 Wonderful! (2,156 reviews)
Everything more than i expected
Reviewed on Dec 3, 2025
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Discover the most popular places to visit in Texas Medical Center
MD Anderson Cancer Center
4.5/5(788 reviews)
Though MD Anderson Cancer Center might be what brings you to town, perhaps you'll have a chance to explore more of Houston while you are here.
Texas Children's Hospital
4.5/5(26 reviews)
Though Texas Children's Hospital might be what brings you to town, perhaps you'll have a chance to explore more of Houston while you are here.
Harris Health System - Ben Taub General Hospital
Though Harris Health System - Ben Taub General Hospital might be what brings you to town, perhaps you'll have a chance to explore more of Houston while you are here.
Things to do
Houston: Houston Botanic Garden Entry Ticket
$12
per adult
80% of travellers recommend
Houston Museum of Natural Science: Cockrell Butterfly Center
$15
per adult
100% of travellers recommend
Houston Museum of Natural Science General Admission Ticket
$25
per adult
96% of travellers recommend
Explore a world of travel with Expedia
- Houston Hotels
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- Houston Zoo
- MD Anderson Cancer Center
- Hermann Park
- Rice University
- Reckling Park
- Houston Vacations
- Rice Stadium
- Miller Outdoor Theater
- NRG Stadium
- Visit Astrodome
- James Turrell's Twilight Epiphany Skyscape
- Houston Natural Science Museum
- Houston Museum of Fine Arts
- NRG Park
- Houston Museum District Vacations
- Children's Museum of Houston
- Holocaust Museum Houston
- Cullen Sculpture Garden
- Visit Riverside Terrace
- Buffalo Soldiers National Museum
- Visit Houston Museum District
- Car rentals near Houston
- Car rentals near MD Anderson Cancer Center
- Standard Car Rentals near MD Anderson Cancer Center
- Car rentals near Houston Zoo
- Sportscar Car Rentals near Houston Zoo
- Car rentals near Hermann Park
- Car rentals near Rice University
- Pickup Car Rentals near Rice University
- SUV Car Rentals near Rice University
- Van Car Rentals near Rice University
- Car rentals near James Turrell's Twilight Epiphany Skyscape
- Car rentals near Houston Museum District
- Thrifty Car Rental Rental Cars in Houston Museum District
- Hertz Rental Cars in Houston Museum District
- Alamo Rent A Car Rental Cars in Houston Museum District
- Pickup Car Rentals in Houston Museum District
- Sixt Rental Cars in Houston Museum District
- Discount Quebec Rental Cars in Houston Museum District
- Budget Rental Cars in Houston Museum District
- Enterprise Rental Cars in Houston Museum District
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.