Texas Medical Center Vacations from $215
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Your Texas Medical Center Vacation
Texas Medical Center is calling! Whatever type of break you're organizing, you can see and experience the best of this neighborhood with a Texas Medical Center vacation package. Your trip to Texas Medical Center wouldn't be complete without a stop at top attractions nearby such as Houston Zoo, Houston Natural Science Museum and Childrens Museum of Houston. Whatever your travel plans or the size of your budget, booking a perfect Texas Medical Center vacation is quick and easy with Expedia.
The Latest Texas Medical Center Vacation Packages
Price found within the past 48 hours. Click for updated prices.
OYO Hotel Houston N Fm-1960 Champions TX
Save 100% on your flight
Price was $351, price is now $215 per person
$215
per person
Feb 20 - Feb 27
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to Houston (IAH)
6.4/10 (186 reviews)
It was all right. It wasn’t the best.
The sheets had holes in them from people who smoked before, the bed was comfortable and I slept well
Reviewed on Nov 20, 2025
Rusk House Serviced Apartments
Downtown Houston
Price was $1,256, price is now $591 per person
$591
per person
Feb 20 - Feb 27
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to Houston (IAH)
9.2/10 Wonderful! (296 reviews)
Really comfortable stay, friendly staff, plenty of public transit options nearby too.
Reviewed on Dec 18, 2025
Blossom Hotel Houston, Curio Collection by Hilton
Texas Medical Center
Save 100% on your flight
Price was $1,052, price is now $598 per person
$598
per person
Feb 20 - Feb 27
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to Houston (IAH)
9/10 Wonderful! (3,554 reviews)
Melvin front desk and Wilker in restaurant
Reviewed on Dec 20, 2025
Hotel Granduca Houston
The Galleria
Save 100% on your flight
Price was $1,201, price is now $741 per person
$741
per person
Feb 27 - Mar 2
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to Houston (IAH)
9.2/10 Wonderful! (1,002 reviews)
This is literally one of the Best Hotel I have stayed at. I loved everything about it. I would highly recommend it. I was there with friends celebrating my birthday. Everyone had an amazing time…
Reviewed on Dec 18, 2025
Where to stay in Texas Medical Center
Find the best Texas Medical Center areas and neighborhoods for the activities you enjoy most. Learn more about Texas Medical Center
Downtown Houston
3 out of top 10 points of interest in this area
4.5/5(2,300 area reviews)
Largest central business district in Texas, this area boasts major league sports venues, a vibrant Theater District, and shopping options like GreenStreet. Easily navigate with public transportation options like METRORail and bus lines.
Texas Medical Center Hotel Deals
Blossom Hotel Houston, Curio Collection by Hilton
7118 Bertner Ave Houston TX
Fully refundableReserve now, pay when you stay
$130 nightly
The price is $153 total per night from Jan 18 to Jan 19
$153 total
Jan 18 - Jan 19, 2026
Total with taxes and fees
9/10 Wonderful! (3,601 reviews)
All was good
Reviewed on Dec 17, 2025
Hilton Houston Plaza/Medical Center
6633 Travis St Houston TX
Fully refundableReserve now, pay when you stay
$87 nightly
The price is $102 total per night from Dec 25 to Dec 26
$102 total
Dec 25 - Dec 26
Total with taxes and fees
8.2/10 Very Good! (1,753 reviews)
Very good
Reviewed on Dec 14, 2025
The Westin Houston Medical Center/Museum District
1709 DRYDEN ROAD Houston TX
Fully refundableReserve now, pay when you stay
$163 nightly
The price is $189 total per night from Dec 21 to Dec 22
$189 total
Dec 21 - Dec 22
Total with taxes and fees
9/10 Wonderful! (1,012 reviews)
Staff are very friendly and attentive. Hotel is clean no maintenance issue noted by any means. Location was easily accessible by uber. Rooms were quiet except for when emergency sirens go off (mind you I was on the ninth floor). Bed and bedding were very superb especially when the weather outside ...
Reviewed on Dec 13, 2025
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Discover the most popular places to visit in Texas Medical Center
MD Anderson Cancer Center
Though MD Anderson Cancer Center might be what brings you to town, perhaps you'll have a chance to explore more of Houston while you are here.
Texas Children's Hospital
Though Texas Children's Hospital might be what brings you to town, perhaps you'll have a chance to explore more of Houston while you are here.
Harris Health System - Ben Taub General Hospital
Though Harris Health System - Ben Taub General Hospital might be what brings you to town, perhaps you'll have a chance to explore more of Houston while you are here.
Things to do
Houston: Houston Botanic Garden Entry Ticket
$12
per adult
80% of travellers recommend
Houston Museum of Natural Science General Admission Ticket
$25
per adult
96% of travellers recommend
Houston Museum of Natural Science: Cockrell Butterfly Center
$15
per adult
100% of travellers recommend
Explore a world of travel with Expedia
- Houston Hotels
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- Houston Zoo
- MD Anderson Cancer Center
- Hermann Park
- Rice University
- Reckling Park
- Houston Vacations
- Rice Stadium
- Miller Outdoor Theater
- NRG Stadium
- Visit Astrodome
- James Turrell's Twilight Epiphany Skyscape
- Houston Natural Science Museum
- Houston Museum of Fine Arts
- NRG Park
- Houston Museum District Vacations
- Children's Museum of Houston
- Holocaust Museum Houston
- Cullen Sculpture Garden
- Visit Riverside Terrace
- Buffalo Soldiers National Museum
- Visit Houston Museum District
- Car rentals near Houston
- Car rentals near MD Anderson Cancer Center
- Standard Car Rentals near MD Anderson Cancer Center
- Car rentals near Houston Zoo
- Sportscar Car Rentals near Houston Zoo
- Car rentals near Hermann Park
- Car rentals near Rice University
- Pickup Car Rentals near Rice University
- SUV Car Rentals near Rice University
- Van Car Rentals near Rice University
- Car rentals near James Turrell's Twilight Epiphany Skyscape
- Car rentals near Houston Museum District
- Thrifty Car Rental Rental Cars in Houston Museum District
- Hertz Rental Cars in Houston Museum District
- Alamo Rent A Car Rental Cars in Houston Museum District
- Pickup Car Rentals in Houston Museum District
- Sixt Rental Cars in Houston Museum District
- Discount Quebec Rental Cars in Houston Museum District
- Budget Rental Cars in Houston Museum District
- Enterprise Rental Cars in Houston Museum District
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.