Texas Medical Center Vacations from $164

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Your Texas Medical Center Vacation

Texas Medical Center is calling! Whatever type of break you're organizing, you can see and experience the best of this neighborhood with a Texas Medical Center vacation package. Your trip to Texas Medical Center wouldn't be complete without a stop at top attractions nearby such as Houston Zoo, Houston Natural Science Museum and Childrens Museum of Houston. Whatever your travel plans or the size of your budget, booking a perfect Texas Medical Center vacation is quick and easy with Expedia.

The Latest Texas Medical Center Vacation Packages

Price found within the past 48 hours. Click for updated prices.
Holiday Inn & Suites Houston NW - Willowbrook by IHG
Hampton Inn & Suites Houston Sugar Land
Hampton Inn & Suites Houston Heights I-10
Hampton Inn & Suites Houston/League City
Margaritaville Lake Resort, Lake Conroe/Houston

Where to stay in Texas Medical Center

Find the best Texas Medical Center areas and neighborhoods for the activities you enjoy most. Learn more about Texas Medical Center

Texas Medical Center Hotel Deals

Blossom Hotel Houston, Curio Collection by Hilton

Blossom Hotel Houston, Curio Collection by Hilton

4 out of 5
7118 Bertner Ave, Houston, TX
Fully refundableReserve now, pay when you stay
$146 nightly
The price is $170 total per night from Dec 8 to Dec 9
$170 total
Dec 8 - Dec 9
Total with taxes and fees
9/10 Wonderful! (3,547 reviews)
The hotel is beautiful and clean. Our room was spacious, clean, quiet and beautiful. The staff was courteous and helpful. And the restaurant was fabulous. The food was delicious and the Service was excellent. I chose this hotel because it has a restaurant that serves 3 meals per day and it was worth ...

Reviewed on Nov 6, 2025

Blossom Hotel Houston, Curio Collection by Hilton
Hyatt Place Houston Medical Center

Hyatt Place Houston Medical Center

3 out of 5
7329 FANNIN STREET Building 2, Houston, TX
Fully refundableReserve now, pay when you stay
$119 nightly
The price is $139 total per night from Nov 23 to Nov 24
$139 total
Nov 23 - Nov 24
Total with taxes and fees
9/10 Wonderful! (2,086 reviews)
Quick

Reviewed on Nov 2, 2025

Hyatt Place Houston Medical Center
Hilton Houston Plaza/Medical Center

Hilton Houston Plaza/Medical Center

4.5 out of 5
6633 Travis St, Houston, TX
Fully refundableReserve now, pay when you stay
$89 nightly
The price is $105 total per night from Nov 30 to Dec 1
$105 total
Nov 30 - Dec 1
Total with taxes and fees
8.2/10 Very Good! (1,651 reviews)
Yes n yes

Reviewed on Nov 4, 2025

Hilton Houston Plaza/Medical Center
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

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* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.