Texas Medical Center Vacations from $200
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Your Texas Medical Center Vacation
Texas Medical Center is calling! Whatever type of break you're organizing, you can see and experience the best of this neighborhood with a Texas Medical Center vacation package. Your trip to Texas Medical Center wouldn't be complete without a stop at top attractions nearby such as Houston Zoo, Houston Natural Science Museum and Childrens Museum of Houston. Whatever your travel plans or the size of your budget, booking a perfect Texas Medical Center vacation is quick and easy with Expedia.
The Latest Texas Medical Center Vacation Packages
Price found within the past 48 hours. Click for updated prices.
Palace Inn Blue Edgebrook
Southeast Houston
Price was $564, price is now $369 per person
$369
per person
Feb 16 - Feb 21
found 17 hours ago
Roundtrip non-stop flight included
New York (LGA) to Houston (IAH)
9.4/10 Exceptional! (142 reviews)
Such a great place to stay! Absolutely amazing!
Reviewed on Oct 13, 2025
Hampton Inn Houston Downtown
Downtown Houston
Save 100% on your flight
Price was $741, price is now $486 per person
$486
per person
Jan 7 - Jan 12
found 3 hours ago
Roundtrip flight included
Atlanta (ATL) to Houston (IAH)
8.8/10 Excellent! (1,001 reviews)
Clean rooms and nice staff! They were very accommodating for our event with late check out!
Reviewed on Dec 8, 2025
Margaritaville Lake Resort, Lake Conroe/Houston
Save 100% on your flight
Price was $888, price is now $589 per person
$589
per person
Feb 20 - Feb 23
found 22 hours ago
Roundtrip flight included
Newark Liberty Intl. Airport (EWR) to Houston (IAH)
8.2/10 Very Good! (1,006 reviews)
No free breakfast, no microwave (rediculous), very hard to find light switches for lamps, no wifii, parking far from entrance altho shuttle was helpful. Beautiful sunrise and sunset…..oh wait…God made those.
Reviewed on Dec 4, 2025
Le Meridien Houston Downtown
Downtown Houston
Save 100% on your flight
Price was $531, price is now $365 per person
$365
per person
Jan 30 - Feb 2
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to Houston (IAH)
8.8/10 Excellent! (1,005 reviews)
Great room plenty of space staff was extremely friendly. Had a great time here
Reviewed on Dec 8, 2025
Where to stay in Texas Medical Center
Find the best Texas Medical Center areas and neighborhoods for the activities you enjoy most. Learn more about Texas Medical Center
Downtown Houston
3 out of top 10 points of interest in this area
4.5/5(2,300 area reviews)
Largest central business district in Texas, this area boasts major league sports venues, a vibrant Theater District, and shopping options like GreenStreet. Easily navigate with public transportation options like METRORail and bus lines.
Texas Medical Center Hotel Deals
Blossom Hotel Houston, Curio Collection by Hilton
7118 Bertner Ave Houston TX
Fully refundableReserve now, pay when you stay
$123 nightly
The price is $144 total per night from Dec 15 to Dec 16
$144 total
Dec 15 - Dec 16
Total with taxes and fees
9/10 Wonderful! (3,594 reviews)
Staff was excellent
Reviewed on Dec 6, 2025
Hilton Houston Plaza/Medical Center
6633 Travis St Houston TX
Fully refundableReserve now, pay when you stay
$94 nightly
The price is $110 total per night from Dec 28 to Dec 29
$110 total
Dec 28 - Dec 29
Total with taxes and fees
8.2/10 Very Good! (1,716 reviews)
Great
Reviewed on Dec 3, 2025
The Westin Houston Medical Center/Museum District
1709 DRYDEN ROAD Houston TX
Fully refundableReserve now, pay when you stay
$173 nightly
The price is $201 total per night from Dec 18 to Dec 19
$201 total
Dec 18 - Dec 19
Total with taxes and fees
9/10 Wonderful! (1,000 reviews)
My stay was great. Location was perfect. I wasn’t far from places I needed to uber to. I will be back.
Reviewed on Nov 29, 2025
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Discover the most popular places to visit in Texas Medical Center
MD Anderson Cancer Center
Though MD Anderson Cancer Center might be what brings you to town, perhaps you'll have a chance to explore more of Houston while you are here.
Texas Children's Hospital
Though Texas Children's Hospital might be what brings you to town, perhaps you'll have a chance to explore more of Houston while you are here.
Harris Health System - Ben Taub General Hospital
Though Harris Health System - Ben Taub General Hospital might be what brings you to town, perhaps you'll have a chance to explore more of Houston while you are here.
Things to do
Houston: Houston Botanic Garden Entry Ticket
$12
per adult
80% of travellers recommend
Houston Museum of Natural Science: Cockrell Butterfly Center
$15
per adult
100% of travellers recommend
Houston Museum of Natural Science General Admission Ticket
$25
per adult
96% of travellers recommend
Explore a world of travel with Expedia
- Houston Hotels
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- Houston Zoo
- MD Anderson Cancer Center
- Hermann Park
- Rice University
- Reckling Park
- Houston Vacations
- Rice Stadium
- Miller Outdoor Theater
- NRG Stadium
- Visit Astrodome
- James Turrell's Twilight Epiphany Skyscape
- Houston Natural Science Museum
- Houston Museum of Fine Arts
- NRG Park
- Houston Museum District Vacations
- Children's Museum of Houston
- Holocaust Museum Houston
- Cullen Sculpture Garden
- Visit Riverside Terrace
- Buffalo Soldiers National Museum
- Visit Houston Museum District
- Car rentals near Houston
- Car rentals near MD Anderson Cancer Center
- Standard Car Rentals near MD Anderson Cancer Center
- Car rentals near Houston Zoo
- Sportscar Car Rentals near Houston Zoo
- Car rentals near Hermann Park
- Car rentals near Rice University
- Pickup Car Rentals near Rice University
- SUV Car Rentals near Rice University
- Van Car Rentals near Rice University
- Car rentals near James Turrell's Twilight Epiphany Skyscape
- Car rentals near Houston Museum District
- Thrifty Car Rental Rental Cars in Houston Museum District
- Hertz Rental Cars in Houston Museum District
- Alamo Rent A Car Rental Cars in Houston Museum District
- Pickup Car Rentals in Houston Museum District
- Sixt Rental Cars in Houston Museum District
- Discount Quebec Rental Cars in Houston Museum District
- Budget Rental Cars in Houston Museum District
- Enterprise Rental Cars in Houston Museum District
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.