Texas Medical Center Vacations from $177
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Your Texas Medical Center Vacation
Texas Medical Center is calling! Whatever type of break you're organizing, you can see and experience the best of this neighborhood with a Texas Medical Center vacation package. Your trip to Texas Medical Center wouldn't be complete without a stop at top attractions nearby such as Houston Zoo, Houston Natural Science Museum and Childrens Museum of Houston. Whatever your travel plans or the size of your budget, booking a perfect Texas Medical Center vacation is quick and easy with Expedia.
The Latest Texas Medical Center Vacation Packages
Price found within the past 48 hours. Click for updated prices.
Margaritaville Lake Resort, Lake Conroe/Houston
Save 100% on your flight
Price was $1,147, price is now $713 per person
$713
per person
Dec 4 - Dec 7
found 1 day ago
Roundtrip non-stop flight included
Philadelphia (PHL) to Houston (IAH)
8.2/10 Very Good! (1,005 reviews)
A dressing area would be nice for guests who stay overnight and wish to use the amenities the next day. Also, lockers would have been useful.
Reviewed on Sep 19, 2025
DoubleTree by Hilton Hotel & Suites Houston by the Galleria
Greater Uptown
Save 100% on your flight
Price was $361, price is now $226 per person
$226
per person
Oct 24 - Oct 27
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to Houston (IAH)
8.2/10 Very Good! (2,472 reviews)
Very clean, safe. Checking was easy and the stag súper kind
Reviewed on Sep 19, 2025
Residence Inn by Marriott Houston Northwest/Cypress
Save 100% on your flight
Price was $478, price is now $318 per person
$318
per person
Dec 11 - Dec 16
found 17 hours ago
Roundtrip flight included
Atlanta (ATL) to Houston (IAH)
9/10 Wonderful! (557 reviews)
Everything was positive!
Reviewed on Sep 17, 2025
Hotel Saint Augustine
Montrose
Price was $929, price is now $622 per person
$622
per person
Nov 6 - Nov 9
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to Houston (IAH)
9.8/10 Exceptional! (32 reviews)
Very unique property very quaint, private beautiful grounds, convenient to a lot of museums and restaurants
Reviewed on Sep 1, 2025
Where to stay in Texas Medical Center
Find the best Texas Medical Center areas and neighborhoods for the activities you enjoy most. Learn more about Texas Medical Center
Downtown Houston
3 out of top 10 points of interest in this area
4.5/5(2,300 area reviews)
Largest central business district in Texas, this area boasts major league sports venues, a vibrant Theater District, and shopping options like GreenStreet. Easily navigate with public transportation options like METRORail and bus lines.
Texas Medical Center Hotel Deals
Blossom Hotel Houston
7118 Bertner Ave, Houston, TX
Fully refundableReserve now, pay when you stay
$139 nightly
The price is $163 total per night from Oct 22 to Oct 23
$163 total
Oct 22 - Oct 23
Total with taxes and fees
9/10 Wonderful! (3,510 reviews)
Best Hotel in the Medical Center!
"We have stayed at Blossum twice now. The hotel is beautiful. It is only 4 years old. The beds are very comfortable and the rooms are spacious. The restaurant staff are welcoming. The Ribeye and Short Ribs are a must have. We will definitely be going back!"
Reviewed on Sep 17, 2025
Hilton Houston Plaza/Medical Center
6633 Travis St, Houston, TX
Fully refundableReserve now, pay when you stay
$107 nightly
The price is $125 total per night from Oct 5 to Oct 6
$125 total
Oct 5 - Oct 6
Total with taxes and fees
8.2/10 Very Good! (1,592 reviews)
"Proximity to Medical Center"
Reviewed on Sep 17, 2025
Hyatt Place Houston Medical Center
7329 FANNIN STREET Building 2, Houston, TX
Fully refundableReserve now, pay when you stay
$140 nightly
The price is $163 total per night from Sep 22 to Sep 23
$163 total
Sep 22 - Sep 23
Total with taxes and fees
9/10 Wonderful! (1,986 reviews)
"Staff was attentive and friendly"
Reviewed on Sep 20, 2025
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Discover the most popular places to visit in Texas Medical Center
MD Anderson Cancer Center
Though MD Anderson Cancer Center might be what brings you to town, perhaps you'll have a chance to explore more of Houston while you are here.
Texas Children's Hospital
Though Texas Children's Hospital might be what brings you to town, perhaps you'll have a chance to explore more of Houston while you are here.
Harris Health System - Ben Taub General Hospital
Though Harris Health System - Ben Taub General Hospital might be what brings you to town, perhaps you'll have a chance to explore more of Houston while you are here.
Things to do
Houston: Houston Botanic Garden Entry Ticket
$12
per adult
80% of travellers recommend
Houston Museum of Natural Science General Admission Ticket
$25
per adult
98% of travellers recommend
Explore a world of travel with Expedia
Explore a world of travel with Expedia
- Houston Hotels
- Hotels near MD Anderson Cancer Center
- Hotels near Downtown Houston
- Hotels near NRG Stadium
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- Hotels near Reckling Park
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- Houston Zoo
- MD Anderson Cancer Center
- Hermann Park
- Rice University
- Reckling Park
- Houston Vacations
- Rice Stadium
- Miller Outdoor Theater
- NRG Stadium
- Visit Astrodome
- James Turrell's Twilight Epiphany Skyscape
- Houston Natural Science Museum
- Houston Museum of Fine Arts
- NRG Park
- Houston Museum District Vacations
- Children's Museum of Houston
- Holocaust Museum Houston
- Cullen Sculpture Garden
- Visit Riverside Terrace
- Buffalo Soldiers National Museum
- Visit Houston Museum District
- Car rentals near Houston
- Car rentals near MD Anderson Cancer Center
- Standard Car Rentals near MD Anderson Cancer Center
- Car rentals near Houston Zoo
- Sportscar Car Rentals near Houston Zoo
- Car rentals near Hermann Park
- Car rentals near Rice University
- Pickup Car Rentals near Rice University
- SUV Car Rentals near Rice University
- Van Car Rentals near Rice University
- Car rentals near James Turrell's Twilight Epiphany Skyscape
- Car rentals near Houston Museum District
- Thrifty Car Rental Rental Cars in Houston Museum District
- Hertz Rental Cars in Houston Museum District
- Alamo Rent A Car Rental Cars in Houston Museum District
- Pickup Car Rentals in Houston Museum District
- Sixt Rental Cars in Houston Museum District
- Discount Quebec Rental Cars in Houston Museum District
- Budget Rental Cars in Houston Museum District
- Enterprise Rental Cars in Houston Museum District
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.