Texas Medical Center Vacations from $220
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Your Texas Medical Center Vacation
Texas Medical Center is calling! Whatever type of break you're organizing, you can see and experience the best of this neighborhood with a Texas Medical Center vacation package. Your trip to Texas Medical Center wouldn't be complete without a stop at top attractions nearby such as Houston Zoo, Houston Natural Science Museum and Childrens Museum of Houston. Whatever your travel plans or the size of your budget, booking a perfect Texas Medical Center vacation is quick and easy with Expedia.
The Latest Texas Medical Center Vacation Packages
Price found within the past 48 hours. Click for updated prices.
La Quinta Inn & Suites by Wyndham Houston East at Normandy
Northeast Houston
Save 100% on your flight
per person
Sep 25 - Sep 30
found 8 hours ago
Roundtrip flight included
New York (LGA) to Houston (IAH)
8/10 Very Good! (634 reviews)
Hotel staff very friendly food was great room was perfect. Most of all the staff
Reviewed on Jul 6, 2025
Palace Inn Blue Edgebrook
Southeast Houston
Save 100% on your flight
per person
Oct 7 - Oct 14
found 24 hours ago
Roundtrip flight included
Newark Liberty Intl. Airport (EWR) to Houston (IAH)
9.4/10 Exceptional! (122 reviews)
The area was under construction so it was a bit hard to find but the staff was nice and welcoming. We did find a small issue with the room but it didn’t affect the stay that much and just threw it away and had a good laugh about it.
Reviewed on Jul 1, 2025
The Mansion on 17th
East End
Save 100% on your flight
per person
Oct 7 - Oct 14
found 1 day ago
Roundtrip flight included
Newark Liberty Intl. Airport (EWR) to Houston (IAH)
9.6/10 Exceptional! (677 reviews)
Every room is unique and lovely! Mine has a balcony, a sitting area with TV, clawfoot tub/shower, beautiful chandelier. Old world charm abounds!
Reviewed on Jul 14, 2025
Where to stay in Texas Medical Center
Find the best Texas Medical Center areas and neighborhoods for the activities you enjoy most. Learn more about Texas Medical Center
Downtown Houston
3 out of top 10 points of interest in this area
4.5/5(2,300 area reviews)
Largest central business district in Texas, this area boasts major league sports venues, a vibrant Theater District, and shopping options like GreenStreet. Easily navigate with public transportation options like METRORail and bus lines.
Texas Medical Center Hotel Deals
Blossom Hotel Houston
7118 Bertner Ave, Houston, TX
Fully refundableReserve now, pay when you stay
$132 nightly
The price is $155 total per night from Jul 20 to Jul 21
$155 total
Jul 20 - Jul 21
Total includes taxes and fees
9/10 Wonderful! (3,408 reviews)
"Very nice and quiet hotel"
Reviewed on Jul 16, 2025
Hilton Houston Plaza/Medical Center
6633 Travis St, Houston, TX
Fully refundableReserve now, pay when you stay
$94 nightly
The price is $110 total per night from Aug 3 to Aug 4
$110 total
Aug 3 - Aug 4
Total includes taxes and fees
8.2/10 Very Good! (1,451 reviews)
Quick doctors visit
"Two day stay for medical reasons. Hotel conveniently located"
Reviewed on Jul 17, 2025
Hyatt Place Houston Medical Center
7329 FANNIN STREET Building 2, Houston, TX
Fully refundableReserve now, pay when you stay
$117 nightly
The price is $137 total per night from Aug 8 to Aug 9
$137 total
Aug 8 - Aug 9
Total includes taxes and fees
9/10 Wonderful! (1,812 reviews)
"It was convenient right by Md Anderson"
Reviewed on Jul 18, 2025
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Discover the most popular places to visit in Texas Medical Center
MD Anderson Cancer Center
4.5/5(788 reviews)
Though MD Anderson Cancer Center might be what brings you to town, perhaps you'll have a chance to explore more of Houston while you are here.
Texas Children's Hospital
4.5/5(26 reviews)
Though Texas Children's Hospital might be what brings you to town, perhaps you'll have a chance to explore more of Houston while you are here.
Harris Health System - Ben Taub General Hospital
Though Harris Health System - Ben Taub General Hospital might be what brings you to town, perhaps you'll have a chance to explore more of Houston while you are here.
Things to do
Houston: Houston Botanic Garden Entry Ticket
$12
per adult
Explore a world of travel with Expedia
Explore a world of travel with Expedia
- Houston Hotels
- Hotels near MD Anderson Cancer Center
- Hotels near Downtown Houston
- Hotels near NRG Stadium
- Cheap Hotels in Houston
- Hotels near TMC Transit Center
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- Apartments in Dryden/TMC Station
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- Hotels near Smith Lands Station
- Hotels near Houston Zoo
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- Hotels near Reckling Park
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- Apartments in Stadium Park/Astrodome Station
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- Hotels near Houston Museum District
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- Houston Zoo
- MD Anderson Cancer Center
- Hermann Park
- Rice University
- Reckling Park
- Houston Vacations
- Rice Stadium
- Miller Outdoor Theater
- NRG Stadium
- Visit Astrodome
- James Turrell's Twilight Epiphany Skyscape
- Houston Natural Science Museum
- Houston Museum of Fine Arts
- NRG Park
- Houston Museum District Vacations
- Children's Museum of Houston
- Holocaust Museum Houston
- Cullen Sculpture Garden
- Visit Riverside Terrace
- Buffalo Soldiers National Museum
- Visit Houston Museum District
- Car rentals near Houston
- Car rentals near MD Anderson Cancer Center
- Standard Car Rentals near MD Anderson Cancer Center
- Car rentals near Houston Zoo
- Sportscar Car Rentals near Houston Zoo
- Car rentals near Hermann Park
- Car rentals near Rice University
- Pickup Car Rentals near Rice University
- SUV Car Rentals near Rice University
- Van Car Rentals near Rice University
- Car rentals near James Turrell's Twilight Epiphany Skyscape
- Car rentals near Houston Museum District
- Thrifty Car Rental Rental Cars in Houston Museum District
- Hertz Rental Cars in Houston Museum District
- Alamo Rent A Car Rental Cars in Houston Museum District
- Pickup Car Rentals in Houston Museum District
- Sixt Rental Cars in Houston Museum District
- Discount Quebec Rental Cars in Houston Museum District
- Budget Rental Cars in Houston Museum District
- Enterprise Rental Cars in Houston Museum District
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.