Texas Medical Center Vacations from $254
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Your Texas Medical Center Vacation
Texas Medical Center is calling! Whatever type of break you're organizing, you can see and experience the best of this neighborhood with a Texas Medical Center vacation package. Your trip to Texas Medical Center wouldn't be complete without a stop at top attractions nearby such as Houston Zoo, Houston Natural Science Museum and Childrens Museum of Houston. Whatever your travel plans or the size of your budget, booking a perfect Texas Medical Center vacation is quick and easy with Expedia.
The Latest Texas Medical Center Vacation Packages
Price found within the past 48 hours. Click for updated prices.
DoubleTree by Hilton Hotel & Suites Houston by the Galleria
Greater Uptown
Price was $806, price is now $418 per person
$418
per person
Feb 20 - Feb 27
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to Houston (IAH)
8.2/10 Very Good! (2,889 reviews)
Check in was quick, staff was courteous.
Reviewed on Dec 14, 2025
Kompose Residences Houston Cy-Fair
Price was $587, price is now $306 per person
$306
per person
Feb 20 - Feb 27
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to Houston (IAH)
10/10 Exceptional! (2 reviews)
Room was very clean and staffs were professional and friendly.
The air conditioner in my bedroom was very loud but wasn’t a bid deal. Limited options for breakfast.
Reviewed on Dec 10, 2025
Blossom Hotel Houston, Curio Collection by Hilton
Texas Medical Center
Price was $1,052, price is now $576 per person
$576
per person
Feb 20 - Feb 27
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to Houston (IAH)
9/10 Wonderful! (3,554 reviews)
Always a great time atc this beautiful hotel, huge room, comfortable bed, gorgeous bathroom with rain shower and Dyson blow dryer, Nespresso machine is an excellent touch, staff is always professional and helpful, yummy Restourant for breakfast and lovely bar with knowledgeable bartenders by the pool! Coming back again and again for the great experience that I receive here, thank you guys!
Reviewed on Dec 14, 2025
Where to stay in Texas Medical Center
Find the best Texas Medical Center areas and neighborhoods for the activities you enjoy most. Learn more about Texas Medical Center
Downtown Houston
3 out of top 10 points of interest in this area
4.5/5(2,300 area reviews)
Largest central business district in Texas, this area boasts major league sports venues, a vibrant Theater District, and shopping options like GreenStreet. Easily navigate with public transportation options like METRORail and bus lines.
Texas Medical Center Hotel Deals
Blossom Hotel Houston, Curio Collection by Hilton
7118 Bertner Ave Houston TX
Fully refundableReserve now, pay when you stay
$137 nightly
The price is $160 total per night from Dec 18 to Dec 19
$160 total
Dec 18 - Dec 19
Total with taxes and fees
9/10 Wonderful! (3,605 reviews)
Always a great time atc this beautiful hotel, huge room, comfortable bed, gorgeous bathroom with rain shower and Dyson blow dryer, Nespresso machine is an excellent touch, staff is always professional and helpful, yummy Restourant for breakfast and lovely bar with knowledgeable bartenders by the ...
Reviewed on Dec 14, 2025
Hilton Houston Plaza/Medical Center
6633 Travis St Houston TX
Fully refundableReserve now, pay when you stay
$89 nightly
The price is $105 total per night from Dec 22 to Dec 23
$105 total
Dec 22 - Dec 23
Total with taxes and fees
8.2/10 Very Good! (1,730 reviews)
If the room had a microwave our stay would have been perfect.
Reviewed on Dec 9, 2025
InterContinental Houston by IHG
6750 Main St Houston TX
Fully refundable
$164 nightly
The price is $192 total per night from Dec 18 to Dec 19
$192 total
Dec 18 - Dec 19
Total with taxes and fees
9.2/10 Wonderful! (1,003 reviews)
Clean room and staff assisted me when I needed help with my rental car. They helped me inflate and directed me to a place to have tire fixed. The head valet person was so accommodating and truly nice.
Reviewed on Dec 12, 2025
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Discover the most popular places to visit in Texas Medical Center
MD Anderson Cancer Center
4.5/5(788 reviews)
Though MD Anderson Cancer Center might be what brings you to town, perhaps you'll have a chance to explore more of Houston while you are here.
Texas Children's Hospital
4.5/5(26 reviews)
Though Texas Children's Hospital might be what brings you to town, perhaps you'll have a chance to explore more of Houston while you are here.
Harris Health System - Ben Taub General Hospital
Though Harris Health System - Ben Taub General Hospital might be what brings you to town, perhaps you'll have a chance to explore more of Houston while you are here.
Things to do
Houston: Houston Botanic Garden Entry Ticket
$12
per adult
80% of travellers recommend
Houston Museum of Natural Science: Cockrell Butterfly Center
$15
per adult
100% of travellers recommend
Houston Museum of Natural Science General Admission Ticket
$25
per adult
96% of travellers recommend
Explore a world of travel with Expedia
- Houston Hotels
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- Houston Zoo
- MD Anderson Cancer Center
- Hermann Park
- Rice University
- Reckling Park
- Houston Vacations
- Rice Stadium
- Miller Outdoor Theater
- NRG Stadium
- Visit Astrodome
- James Turrell's Twilight Epiphany Skyscape
- Houston Natural Science Museum
- Houston Museum of Fine Arts
- NRG Park
- Houston Museum District Vacations
- Children's Museum of Houston
- Holocaust Museum Houston
- Cullen Sculpture Garden
- Visit Riverside Terrace
- Buffalo Soldiers National Museum
- Visit Houston Museum District
- Car rentals near Houston
- Car rentals near MD Anderson Cancer Center
- Standard Car Rentals near MD Anderson Cancer Center
- Car rentals near Houston Zoo
- Sportscar Car Rentals near Houston Zoo
- Car rentals near Hermann Park
- Car rentals near Rice University
- Pickup Car Rentals near Rice University
- SUV Car Rentals near Rice University
- Van Car Rentals near Rice University
- Car rentals near James Turrell's Twilight Epiphany Skyscape
- Car rentals near Houston Museum District
- Thrifty Car Rental Rental Cars in Houston Museum District
- Hertz Rental Cars in Houston Museum District
- Alamo Rent A Car Rental Cars in Houston Museum District
- Pickup Car Rentals in Houston Museum District
- Sixt Rental Cars in Houston Museum District
- Discount Quebec Rental Cars in Houston Museum District
- Budget Rental Cars in Houston Museum District
- Enterprise Rental Cars in Houston Museum District
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.