Texas Medical Center Vacations from $245

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Your Texas Medical Center Vacation

Texas Medical Center is calling! Whatever type of break you're organizing, you can see and experience the best of this neighborhood with a Texas Medical Center vacation package. Your trip to Texas Medical Center wouldn't be complete without a stop at top attractions nearby such as Houston Zoo, Houston Natural Science Museum and Childrens Museum of Houston. Whatever your travel plans or the size of your budget, booking a perfect Texas Medical Center vacation is quick and easy with Expedia.

The Latest Texas Medical Center Vacation Packages

Price found within the past 48 hours. Click for updated prices.
 Palace Inn Blue Edgebrook
Moody Gardens Hotel, Spa and Convention Center
Hampton Inn Houston-Near The Galleria
Blossom Hotel Houston
The Hayworth Apartments By Barsala

Where to stay in Texas Medical Center

Find the best Texas Medical Center areas and neighborhoods for the activities you enjoy most. Learn more about Texas Medical Center

Texas Medical Center Hotel Deals

Blossom Hotel Houston
Blossom Hotel Houston
4 out of 5
7118 Bertner Ave, Houston, TX
Fully refundableReserve now, pay when you stay
$134 nightly
The price is $157 total per night from Jul 31 to Aug 1
$157 total
Jul 31 - Aug 1
Total includes taxes and fees
9/10 Wonderful! (3,376 reviews)
Blossom Hotel is amazing!
"Blossom Hotel was amazing. Friendly staff, beautiful rooms, great food amazing cocktails! I will be back!"

Reviewed on Jun 30, 2025

Blossom Hotel Houston
Hilton Houston Plaza/Medical Center
Hilton Houston Plaza/Medical Center
4.5 out of 5
6633 Travis St, Houston, TX
Fully refundableReserve now, pay when you stay
$96 nightly
The price is $113 total per night from Jul 20 to Jul 21
$113 total
Jul 20 - Jul 21
Total includes taxes and fees
8.2/10 Very Good! (1,408 reviews)
Great hotel clise to the TMC
"The stay was overall very enjoyable — the facilities were clean, comfortable, and well-maintained. The only inconvenience was having just one working elevator, as the other was under maintenance. This led to long wait times at certain hours, which was a bit of a hassle. Aside from that, everything ..."

Reviewed on Jun 29, 2025

Hilton Houston Plaza/Medical Center
Hyatt Place Houston Medical Center
Hyatt Place Houston Medical Center
3 out of 5
7329 FANNIN STREET Building 2, Houston, TX
Fully refundableReserve now, pay when you stay
$130 nightly
The price is $152 total per night from Jul 12 to Jul 13
$152 total
Jul 12 - Jul 13
Total includes taxes and fees
9/10 Wonderful! (1,751 reviews)
"Be aware they will need a card to put a $50 hold at check in and parking is $15 each night"

Reviewed on Jun 30, 2025

Hyatt Place Houston Medical Center
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Discover the most popular places to visit in Texas Medical Center

Things to do

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.