Texas Medical Center Vacations from $245
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Your Texas Medical Center Vacation
Texas Medical Center is calling! Whatever type of break you're organizing, you can see and experience the best of this neighborhood with a Texas Medical Center vacation package. Your trip to Texas Medical Center wouldn't be complete without a stop at top attractions nearby such as Houston Zoo, Houston Natural Science Museum and Childrens Museum of Houston. Whatever your travel plans or the size of your budget, booking a perfect Texas Medical Center vacation is quick and easy with Expedia.
The Latest Texas Medical Center Vacation Packages
Price found within the past 48 hours. Click for updated prices.
Palace Inn Blue Edgebrook
Southeast Houston
Save 100% on your flight
per person
Sep 11 - Sep 16
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to Houston (IAH)
9.2/10 Wonderful! (117 reviews)
The area was under construction so it was a bit hard to find but the staff was nice and welcoming. We did find a small issue with the room but it didn’t affect the stay that much and just threw it away and had a good laugh about it.
Reviewed on Jul 1, 2025
Moody Gardens Hotel, Spa and Convention Center
Near West End
per person
Sep 21 - Sep 26
found 5 hours ago
Roundtrip flight included
New York (LGA) to Houston (IAH)
8.8/10 Excellent! (1,818 reviews)
De verdad que el hotel es una belleza las habitaciones muy limpias. Me sentí muy a gusto lleno de glamour
Reviewed on Jun 30, 2025
Hampton Inn Houston-Near The Galleria
The Galleria
Save 100% on your flight
per person
Aug 6 - Aug 11
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to Houston (IAH)
7.8/10 Good! (1,012 reviews)
This hotel was awesome. The staff was super friendly and accommodating when we had some delays/issues with our airline. Anything we asked they assisted with. The location is great, close to the Galleria mall without feeling overly crowded. Breakfast was hot and tasty every morning. Would definitely recommend and stay here again!
Reviewed on Jun 30, 2025
Where to stay in Texas Medical Center
Find the best Texas Medical Center areas and neighborhoods for the activities you enjoy most. Learn more about Texas Medical Center
Downtown Houston
3 out of top 10 points of interest in this area
4.5/5(2,300 area reviews)
Largest central business district in Texas, this area boasts major league sports venues, a vibrant Theater District, and shopping options like GreenStreet. Easily navigate with public transportation options like METRORail and bus lines.
Texas Medical Center Hotel Deals
Blossom Hotel Houston
7118 Bertner Ave, Houston, TX
Fully refundableReserve now, pay when you stay
$134 nightly
The price is $157 total per night from Jul 31 to Aug 1
$157 total
Jul 31 - Aug 1
Total includes taxes and fees
9/10 Wonderful! (3,376 reviews)
Blossom Hotel is amazing!
"Blossom Hotel was amazing. Friendly staff, beautiful rooms, great food amazing cocktails! I will be back!"
Reviewed on Jun 30, 2025
Hilton Houston Plaza/Medical Center
6633 Travis St, Houston, TX
Fully refundableReserve now, pay when you stay
$96 nightly
The price is $113 total per night from Jul 20 to Jul 21
$113 total
Jul 20 - Jul 21
Total includes taxes and fees
8.2/10 Very Good! (1,408 reviews)
Great hotel clise to the TMC
"The stay was overall very enjoyable — the facilities were clean, comfortable, and well-maintained. The only inconvenience was having just one working elevator, as the other was under maintenance. This led to long wait times at certain hours, which was a bit of a hassle. Aside from that, everything ..."
Reviewed on Jun 29, 2025
Hyatt Place Houston Medical Center
7329 FANNIN STREET Building 2, Houston, TX
Fully refundableReserve now, pay when you stay
$130 nightly
The price is $152 total per night from Jul 12 to Jul 13
$152 total
Jul 12 - Jul 13
Total includes taxes and fees
9/10 Wonderful! (1,751 reviews)
"Be aware they will need a card to put a $50 hold at check in and parking is $15 each night"
Reviewed on Jun 30, 2025
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Discover the most popular places to visit in Texas Medical Center
MD Anderson Cancer Center
4.5/5(788 reviews)
Though MD Anderson Cancer Center might be what brings you to town, perhaps you'll have a chance to explore more of Houston while you are here.
Texas Children's Hospital
4.5/5(26 reviews)
Though Texas Children's Hospital might be what brings you to town, perhaps you'll have a chance to explore more of Houston while you are here.
Harris Health System - Ben Taub General Hospital
Though Harris Health System - Ben Taub General Hospital might be what brings you to town, perhaps you'll have a chance to explore more of Houston while you are here.
Things to do
Houston: Houston Botanic Garden Entry Ticket
$12
per adult
Spa-Quality On Demand Massage - Houston
$129
per adult
76% of travellers recommend
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- Houston Hotels
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- Houston Zoo
- MD Anderson Cancer Center
- Hermann Park
- Rice University
- Reckling Park
- Houston Vacations
- Rice Stadium
- Miller Outdoor Theater
- NRG Stadium
- Visit Astrodome
- James Turrell's Twilight Epiphany Skyscape
- Houston Natural Science Museum
- Houston Museum of Fine Arts
- NRG Park
- Houston Museum District Vacations
- Children's Museum of Houston
- Holocaust Museum Houston
- Cullen Sculpture Garden
- Visit Riverside Terrace
- Buffalo Soldiers National Museum
- Visit Houston Museum District
- Car rentals near Houston
- Car rentals near MD Anderson Cancer Center
- Standard Car Rentals near MD Anderson Cancer Center
- Car rentals near Houston Zoo
- Sportscar Car Rentals near Houston Zoo
- Car rentals near Hermann Park
- Car rentals near Rice University
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- Van Car Rentals near Rice University
- Car rentals near James Turrell's Twilight Epiphany Skyscape
- Car rentals near Houston Museum District
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- Hertz Rental Cars in Houston Museum District
- Alamo Rent A Car Rental Cars in Houston Museum District
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- Sixt Rental Cars in Houston Museum District
- Discount Quebec Rental Cars in Houston Museum District
- Budget Rental Cars in Houston Museum District
- Enterprise Rental Cars in Houston Museum District
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.