A bench, a bicycle, and a lake surrounded by trees.

Upstate South Carolina Vacation Rentals

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Check prices for these dates

In two weeks
Sep 18 - Sep 20
In two months
Oct 30 - Nov 1
In three months
Nov 27 - Nov 29
In four months
Dec 25 - Dec 27

Our top choices for Upstate South Carolina vacation rentals

1. Patriot Point A

Patriot Point A
Roebuck
10.0 out of 10, Exceptional, (27 reviews)
"Fabulous!! Will definitely stay again! "
United States
Kristen H.
$145 nightly
The price is $161
Sep 21 - Sep 22
Total with taxes and fees
Patriot Point A
A rustic interior with a brick fireplace, wooden furniture, and a stone floor.

2. Whiffletree Farmhouse just 2 mins off I-26 & 8 mins from downtown Spartanburg!

Whiffletree Farmhouse just 2 mins off I-26 & 8 mins from downtown Spartanburg!
Roebuck
10.0 out of 10, Exceptional, (42 reviews)
"Awesome farmhouse, will stay here again on future trips!"
United States
Jeremy C.
$254 nightly
The price is $282
Sep 2 - Sep 3
Total with taxes and fees
Whiffletree Farmhouse just 2 mins off I-26 & 8 mins from downtown Spartanburg!
A modern kitchen with white cabinets, stainless steel appliances, and a bar area with stools.

3. Modern Farmhouse in Downtown Simpsonville, SC

Modern Farmhouse in Downtown Simpsonville, SC
Simpsonville
10.0 out of 10, Exceptional, (49 reviews)
"Great place in the heart of lovely Simpsonville, quiet, clean and comfortable."
United States
Ted
$277 nightly
The price is $291
Sep 2 - Sep 3
Total with taxes and fees
Modern Farmhouse in Downtown Simpsonville, SC
A house with a front yard and a paved driveway.

4. ~2 Bedroom Cozy Gem 💎 5 minutes from Downtown Spartanburg~

~2 Bedroom Cozy Gem 💎 5 minutes from Downtown Spartanburg~
Spartanburg
10.0 out of 10, Exceptional, (56 reviews)
"Love this place! We have stayed here twice and it was exactly what we needed and just like the pictures. The wooded lot makes you feel secluded"
United States
Amy B.
$195 nightly
The price is $216
Sep 7 - Sep 8
Total with taxes and fees
~2 Bedroom Cozy Gem 💎 5 minutes from Downtown Spartanburg~
A cabin with a large window, surrounded by trees.

5. Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy

Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy
2.0 star property
Seneca
9.8 out of 10, Exceptional, (101 reviews)
"Me and my family had a great time"
United States
Nirumol
$133 nightly
The price is $146
Sep 9 - Sep 10
Total with taxes and fees
Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy
A modern living room with a sofa, a coffee table, and a TV. There is a kitchen area with a microwave, stove, and refrigerator.

6. Adorable Upscale cottage in Downtown Fountain Inn.

Adorable Upscale cottage in Downtown Fountain Inn.
Fountain Inn
10.0 out of 10, Exceptional, (44 reviews)
"My daughter and son-in-law stayed at the property, and they couldn't say enough about how perfect it was for them during their visit. Clean and pet friendly."
United States
Brian F.
$228 nightly
The price is $251
Sep 6 - Sep 7
Total with taxes and fees
Adorable Upscale cottage in Downtown Fountain Inn.

7. stayAPT Suites Greenville-Haywood Mall

stayAPT Suites Greenville-Haywood Mall
3.0 star property
Greenville
9.2 out of 10, Wonderful, (228 reviews)
"The rooms are spacious and feels like a and apartment. This place is one of the best places to stay."
United States
James
$119 nightly
The price is $131
Sep 4 - Sep 5
Total with taxes and fees
stayAPT Suites Greenville-Haywood Mall
A modern living room with a grey sofa, a round coffee table, and a dining area with a table and chairs.

8. Southern Charm Townhome

Southern Charm Townhome
Simpsonville
9.8 out of 10, Exceptional, (10 reviews)
"Very clean and safe location. Super cute interior decorations and comfortable. Also a great location for us to visit family who are local. Absolutely would stay again."
United States
Brianna F.
$359 nightly
The price is $408
Sep 1 - Sep 2
Total with taxes and fees
Southern Charm Townhome
A kitchen with wooden countertops, white cabinets, and a dishwasher. There is a dining area visible through an open doorway.

9. Whole House, sleeps 7, within walking distance to downtown Spartanburg!

Whole House, sleeps 7, within walking distance to downtown Spartanburg!
Spartanburg
10.0 out of 10, Exceptional, (20 reviews)
"This was a great place to stay for an event in town. Will stay again."
United States
Annette F.
$254 nightly
The price is $281
Sep 1 - Sep 2
Total with taxes and fees
Whole House, sleeps 7, within walking distance to downtown Spartanburg!
A modern kitchen with white cabinets, stainless steel appliances, a granite countertop, and a built-in oven.

10. The Blue Bungalow by Unity Park - Newly Renovated

The Blue Bungalow by Unity Park - Newly Renovated
Woodside Cotton Mill Village Historic District
9.8 out of 10, Exceptional, (105 reviews)
"Fully equipped, comfortable beds…everything to make for an enjoyable stay. "
United States
Ron E.
$205 nightly
The price is $225
Sep 1 - Sep 2
Total with taxes and fees
The Blue Bungalow by Unity Park - Newly Renovated
A spacious living room with two sofas, a coffee table, and a ceiling fan.

11. Peaceful Oasis Convenient to Greenville!

Peaceful Oasis Convenient to Greenville!
Simpsonville
10.0 out of 10, Exceptional, (115 reviews)
"Pet friendly"
United States
Debra C.
$295 nightly
The price is $312
Sep 3 - Sep 4
Total with taxes and fees
Peaceful Oasis Convenient to Greenville!
A house with a gravel driveway, a wooden fence, and a lawn.

12. Secluded Tiny Home in Exclusive Paris Mountain!

Secluded Tiny Home in Exclusive Paris Mountain!
Greenville
10.0 out of 10, Exceptional, (11 reviews)
"Great location, quiet and perfect for a couple stay. "
United States
craig d.
$122 nightly
The price is $134
Sep 1 - Sep 2
Total with taxes and fees
Secluded Tiny Home in Exclusive Paris Mountain!
A spacious porch with wooden flooring, a dining area with a table and chairs, and a view of the surrounding landscape.

13. Carolina Camp Cedar

Carolina Camp Cedar
3.5 star property
Pickens
10.0 out of 10, Exceptional, (3 reviews)
"The cottage was clean, staff was so friendly, our stay was quiet and peaceful… it was perfect! Definitely planning to stay there again!"
United States
Katlynn
$239 nightly
The price is $265
Sep 1 - Sep 2
Total with taxes and fees
Carolina Camp Cedar
A hot tub with string lights in the background.

14. ⭐️Hot Tub⭐️ Luxury Getaway Near GSP Airport Downtown Greer Greenville Spartanburg

⭐️Hot Tub⭐️ Luxury Getaway Near GSP Airport Downtown Greer Greenville Spartanburg
Lyman
10.0 out of 10, Exceptional, (45 reviews)
"Perfect place for a girls weekend trip! Centrally located to lots of areas, we had plenty to do and see and had a great time. Lots of space, very clean, and who doesn’t love a hot tub?!"
United States
Becca C.
$150 nightly
The price is $191
Sep 1 - Sep 2
Total with taxes and fees
⭐️Hot Tub⭐️ Luxury Getaway Near GSP Airport Downtown Greer Greenville Spartanburg
A log cabin with a wooden door, two windows, and a chimney. There are two white metal chairs and a small table in front of the cabin.

15. Historic 19th Century Cabin in Greenville

Historic 19th Century Cabin in Greenville
Greenville
9.4 out of 10, Exceptional, (19 reviews)
"Great cabin in the perfect location. Hosts have thought of everything. Will definitely stay here again! "
United States
David R.
$151 nightly
The price is $166
Sep 7 - Sep 8
Total with taxes and fees
Historic 19th Century Cabin in Greenville
A modern kitchen with white cabinetry, a built-in oven, and a large island with a vase of white orchids.

16. Fairview Luxury Oasis

Fairview Luxury Oasis
Spartanburg
10.0 out of 10, Exceptional, (33 reviews)
"Great place to stay! We loved it!"
United States
John E.
$377 nightly
The price is $418
Sep 3 - Sep 4
Total with taxes and fees
Fairview Luxury Oasis
A swimming pool with lounge chairs and umbrellas, surrounded by brick buildings with large windows.

17. Bright & Cozy 2BR Apt w/ Parking

Bright & Cozy 2BR Apt w/ Parking
Greenville
10.0 out of 10, Exceptional, (11 reviews)
"Excellent stay—spotless room, awesome staff, and great amenities."
United States
Crystal
$225 nightly
The price is $243
Sep 1 - Sep 2
Total with taxes and fees
Bright & Cozy 2BR Apt w/ Parking
A modern kitchen with granite countertops, stainless steel appliances, and a dining area with a sofa and table.

18. 2BR Cedar Lane Road Retreat at Swamp Rabbit Trail!

2BR Cedar Lane Road Retreat at Swamp Rabbit Trail!
Greenville
9.4 out of 10, Exceptional, (38 reviews)
"We had a great stay- the location was close to everything & very clean "
United States
Anonymous traveler
$180 nightly
The price is $198
Sep 7 - Sep 8
Total with taxes and fees
2BR Cedar Lane Road Retreat at Swamp Rabbit Trail!
A hotel room with a bed, a sofa, a small table, a lamp, and a painting on the wall.

19. 1 Queen Bed | Non-Smoking, Micfridge, Sofa-Bed

1 Queen Bed | Non-Smoking, Micfridge, Sofa-Bed
Greenville SC
9.8 out of 10, Exceptional, (51 reviews)
"Great location!"
United States
Anonymous traveler
$69 nightly
The price is $76
Sep 3 - Sep 4
Total with taxes and fees
1 Queen Bed | Non-Smoking, Micfridge, Sofa-Bed
A modern living room with a sofa, a coffee table, a TV, and a balcony with a view of buildings.

20. Mint House Greenville Downtown by Kasa

Mint House Greenville Downtown by Kasa
4.0 star property
Greenville Downtown
9.2 out of 10, Wonderful, (884 reviews)
"Decent room. Very large suite for the price. Beds are too low."
United States
Kenneth
$139 nightly
The price is $153
Sep 7 - Sep 8
Total with taxes and fees
Mint House Greenville Downtown by Kasa
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Upstate South Carolina Hotel Reviews

Embassy Suites Greenville Golf Resort & Conference Center

Embassy Suites Greenville Golf Resort & Conference Center

10/10 Excellent
"Fantastic hotel and price. The staff are so friendly and helpful. This is an older property so it’s not fancy, but very clean and well staffed."
Tammy 3-night trip
Posted less than an hour ago
Embassy Suites Greenville Golf Resort & Conference Center

Find out more about Upstate South Carolina

Everything you need to know about Upstate South Carolina vacation rentals

Whether you’re excited for the perfect family vacation, a romantic getaway for two, or the ultimate city break, we’ve got the Upstate South Carolina vacation rental for you. At Expedia, you can take your pick from private vacation homes, apartments, condos, resorts, cabins, villas, motels. The list goes on, and on …and on.

There’s just as wide a choice of amenities, too. Maybe you’re dreaming of your own pool, long evenings in a hot tub, or watching the kids laugh through the day at a waterpark. Maybe you just want a quiet retreat in a pet-friendly apartment. Well, we can help you find it. Hunt out the perfect Upstate South Carolina vacation rental for you by simply entering your desired dates. Then check your favorite filters to narrow down your search.

Upstate South Carolina vacation rentals: An excellent choice for every season

Whenever you want to travel, a warm welcome awaits you in Upstate South Carolina. If you’re looking for a little peace, consider booking during the quieter low season months. For more hustle and bustle, you may prefer to visit Upstate South Carolina in high season.

Prices vary throughout the year. Your chosen location, property type, and amenities will impact the cost of your trip, too. The selection of properties we have chosen for you start as low as $131 per night. Rates vary depending on your travel dates, location, and amenities so make a search and you might find even better deals!

How to find incredible deals on Upstate South Carolina rentals

At Expedia, we put the best Upstate South Carolina vacation rentals in one place. All you need to do is take your pick. And as we offer book now, pay later options, as well as free cancellation on some properties, you can plan your trip with total peace of mind. You’ll always find a great deal with Expedia.

To find some top Upstate South Carolina rental deals, enter your travel dates, and sort your search results by price. You can also filter by budget, so you only see accommodation in your ballpark. Next, add any filters you want—and just like that, you’ve built your dream Upstate South Carolina vacation.

If you’re looking for a little inspiration, browse our latest incredible offers, or use the map to view all accommodation in and around Upstate South Carolina. And to unlock even more fantastic deals, bundle your accommodation, flights, and car rental together to save and book with Expedia in complete confidence.

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