A bench, a bicycle, and a lake surrounded by trees.

Upstate South Carolina Vacation Rentals

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Check prices for these dates

In two weeks
Sep 18 - Sep 20
In two months
Oct 30 - Nov 1
In three months
Nov 27 - Nov 29
In four months
Dec 25 - Dec 27

Our top choices for Upstate South Carolina vacation rentals

A wooden cabin with a porch, a door, and a hanging hammock.

1. Cozy cabin in the woods! Pets welcome!

Cozy cabin in the woods! Pets welcome!
Enoree
9.6 out of 10, Exceptional, (11 reviews)
"This was a perfect little stay for myself, my husband and our two pups! It was off the beaten path, but still felt very safe."
United States
Christina H.
$167 nightly
The price is $185
Sep 7 - Sep 8
Total with taxes and fees
Cozy cabin in the woods! Pets welcome!
A cabin with a large window, surrounded by trees.

2. Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy

Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy
2.0 star property
Seneca
9.8 out of 10, Exceptional, (101 reviews)
"Me and my family had a great time"
United States
Nirumol
$133 nightly
The price is $146
Oct 5 - Oct 6
Total with taxes and fees
Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy
A modern kitchen with white cabinetry, stainless steel appliances, and a wooden ladder.

3. Charming luxury cottage in the heart of Boiling Springs

Charming luxury cottage in the heart of Boiling Springs
Boiling Springs
8.8 out of 10, Excellent, (15 reviews)
"Very nice guest house. Property was clean and the host was very responsive to our questions. Lots of natural shade in the deck area. Would stay here again."
United States
Pat L.
$192 nightly
The price is $213
Sep 8 - Sep 9
Total with taxes and fees
Charming luxury cottage in the heart of Boiling Springs
A modern living room with a sofa, a coffee table, and a TV. There is a kitchen area with a microwave, stove, and refrigerator.

4. Adorable Upscale cottage in Downtown Fountain Inn.

Adorable Upscale cottage in Downtown Fountain Inn.
Fountain Inn
10.0 out of 10, Exceptional, (44 reviews)
"My daughter and son-in-law stayed at the property, and they couldn't say enough about how perfect it was for them during their visit. Clean and pet friendly."
United States
Brian F.
$229 nightly
The price is $252
Sep 7 - Sep 8
Total with taxes and fees
Adorable Upscale cottage in Downtown Fountain Inn.
A house with a front yard and a paved driveway.

5. ~2 Bedroom Cozy Gem 💎 5 minutes from Downtown Spartanburg~

~2 Bedroom Cozy Gem 💎 5 minutes from Downtown Spartanburg~
Spartanburg
10.0 out of 10, Exceptional, (56 reviews)
"Love this place! We have stayed here twice and it was exactly what we needed and just like the pictures. The wooded lot makes you feel secluded"
United States
Amy B.
$194 nightly
The price is $215
Sep 21 - Sep 22
Total with taxes and fees
~2 Bedroom Cozy Gem 💎 5 minutes from Downtown Spartanburg~
A hotel entrance with glass doors, a caution sign, a potted plant, and a red mat.

6. 2 Queen Beds Non-Smoking

2 Queen Beds Non-Smoking
Greenville SC
10.0 out of 10, Exceptional, (86 reviews)
"Quiet atmosphere throughout the stay made it relaxing."
United States
Anonymous traveler
$63 nightly
The price is $68
Sep 9 - Sep 10
Total with taxes and fees
2 Queen Beds Non-Smoking
A rustic interior with a brick fireplace, wooden furniture, and a stone floor.

7. Whiffletree Farmhouse just 2 mins off I-26 & 8 mins from downtown Spartanburg!

Whiffletree Farmhouse just 2 mins off I-26 & 8 mins from downtown Spartanburg!
Roebuck
10.0 out of 10, Exceptional, (42 reviews)
"Awesome farmhouse, will stay here again on future trips!"
United States
Jeremy C.
$251 nightly
The price is $279
Sep 8 - Sep 9
Total with taxes and fees
Whiffletree Farmhouse just 2 mins off I-26 & 8 mins from downtown Spartanburg!
A modern living room with a grey sofa, a round coffee table, and a dining area with a table and chairs.

8. Southern Charm Townhome

Southern Charm Townhome
Simpsonville
9.8 out of 10, Exceptional, (10 reviews)
"Very clean and safe location. Super cute interior decorations and comfortable. Also a great location for us to visit family who are local. Absolutely would stay again."
United States
Brianna F.
$356 nightly
The price is $405
Sep 7 - Sep 8
Total with taxes and fees
Southern Charm Townhome
A modern kitchen with white cabinets, stainless steel appliances, a granite countertop, and a built-in oven.

9. The Blue Bungalow by Unity Park - Newly Renovated

The Blue Bungalow by Unity Park - Newly Renovated
Woodside Cotton Mill Village Historic District
9.8 out of 10, Exceptional, (106 reviews)
"Fully equipped, comfortable beds…everything to make for an enjoyable stay. "
United States
Ron E.
$203 nightly
The price is $223
Sep 8 - Sep 9
Total with taxes and fees
The Blue Bungalow by Unity Park - Newly Renovated
A house with a gravel driveway, a wooden fence, and a lawn.

10. Secluded Tiny Home in Exclusive Paris Mountain!

Secluded Tiny Home in Exclusive Paris Mountain!
Greenville
10.0 out of 10, Exceptional, (11 reviews)
"Great location, quiet and perfect for a couple stay. "
United States
craig d.
$122 nightly
The price is $134
Sep 7 - Sep 8
Total with taxes and fees
Secluded Tiny Home in Exclusive Paris Mountain!
A modern kitchen with granite countertops, stainless steel appliances, and a dining area with a sofa and table.

11. 2BR Cedar Lane Road Retreat at Swamp Rabbit Trail!

2BR Cedar Lane Road Retreat at Swamp Rabbit Trail!
Greenville
9.4 out of 10, Exceptional, (38 reviews)
"We had a great stay- the location was close to everything & very clean "
United States
Anonymous traveler
$171 nightly
The price is $188
Sep 7 - Sep 8
Total with taxes and fees
2BR Cedar Lane Road Retreat at Swamp Rabbit Trail!
A log cabin with a wooden door, two windows, and a chimney. There are two white metal chairs and a small table in front of the cabin.

12. Historic 19th Century Cabin in Greenville

Historic 19th Century Cabin in Greenville
Greenville
9.4 out of 10, Exceptional, (19 reviews)
"Great cabin in the perfect location. Hosts have thought of everything. Will definitely stay here again! "
United States
David R.
$142 nightly
The price is $156
Sep 7 - Sep 8
Total with taxes and fees
Historic 19th Century Cabin in Greenville
A living room with a sofa, coffee table, and a ceiling fan.

13. Cozy 1BR Close to Downtown & Greenville Drive Baseball

Cozy 1BR Close to Downtown & Greenville Drive Baseball
Greenville
9.2 out of 10, Wonderful, (31 reviews)
"Was a very nice place to stay. I would stay there again. Thank you for the clean place."
United States
Darwin N.
$147 nightly
The price is $162
Sep 7 - Sep 8
Total with taxes and fees
Cozy 1BR Close to Downtown & Greenville Drive Baseball
A bedroom with a herringbone-patterned headboard, a white quilted bedspread, two bedside tables with wall-mounted lamps, a bench at the foot of the bed, and a mirror on the left wall.

14. Kid friendly with playset and pingpong! Central and safe location!

Kid friendly with playset and pingpong! Central and safe location!
Greenville
10.0 out of 10, Exceptional, (58 reviews)
"The house was absolutely perfect! Great location and perfect for our family. My granddaughter loved the toys and swing set. "
United States
Michelle R.
$246 nightly
The price is $263
Sep 7 - Sep 8
Total with taxes and fees
Kid friendly with playset and pingpong! Central and safe location!
A hotel room with a bed, a sofa, a small table, a lamp, and a refrigerator.

15. 1 Queen Bed | Non-Smoking, Micfridge

1 Queen Bed | Non-Smoking, Micfridge
Greenville SC
9.8 out of 10, Exceptional, (50 reviews)
"I absolutely love it here"
United States
Anonymous traveler
$63 nightly
The price is $69
Sep 20 - Sep 21
Total with taxes and fees
1 Queen Bed | Non-Smoking, Micfridge
A swimming pool with lounge chairs and umbrellas, surrounded by brick buildings with large windows.

16. Bright & Cozy 2BR Apt w/ Parking

Bright & Cozy 2BR Apt w/ Parking
Greenville
10.0 out of 10, Exceptional, (13 reviews)
"Excellent stay—spotless room, awesome staff, and great amenities."
United States
Crystal
$216 nightly
The price is $234
Sep 7 - Sep 8
Total with taxes and fees
Bright & Cozy 2BR Apt w/ Parking
A spacious living room with two sofas, a coffee table, and a ceiling fan.

17. Peaceful Oasis Convenient to Greenville!

Peaceful Oasis Convenient to Greenville!
Simpsonville
10.0 out of 10, Exceptional, (115 reviews)
"Pet friendly"
United States
Debra C.
$292 nightly
The price is $308
Sep 8 - Sep 9
Total with taxes and fees
Peaceful Oasis Convenient to Greenville!
A living room with a dark sofa, a coffee table, a lamp, and a flat-screen TV mounted on the wall.

18. Cozy Apt. Near Downtown (2BR, 1BA, 3 beds)

Cozy Apt. Near Downtown (2BR, 1BA, 3 beds)
Greenville
10.0 out of 10, Exceptional, (13 reviews)
"I was provided everything I needed."
United States
Pat
$150 nightly
The price is $165
Sep 7 - Sep 8
Total with taxes and fees
Cozy Apt. Near Downtown (2BR, 1BA, 3 beds)
A spacious porch with wooden flooring, a dining area with a table and chairs, and a view of the surrounding landscape.

19. Carolina Camp Cedar

Carolina Camp Cedar
3.5 star property
Pickens
10.0 out of 10, Exceptional, (3 reviews)
"The cottage was clean, staff was so friendly, our stay was quiet and peaceful… it was perfect! Definitely planning to stay there again!"
United States
Katlynn
$225 nightly
The price is $250
Oct 6 - Oct 7
Total with taxes and fees
Carolina Camp Cedar
A modern kitchen with a stainless steel refrigerator, a microwave, and a sink. There is a wooden dining table with chairs and a laundry basket labeled "laundry" in the foreground.

20. 2BR 2Bath - Swamp Rabbit Trail Resort

2BR 2Bath - Swamp Rabbit Trail Resort
Greenville
9.2 out of 10, Wonderful, (42 reviews)
"Super clean and the king bed was so comfortable. "
United States
Anonymous traveler
$179 nightly
The price is $197
Sep 15 - Sep 16
Total with taxes and fees
2BR 2Bath - Swamp Rabbit Trail Resort
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Upstate South Carolina Hotel Reviews

Comfort Suites At WestGate Mall

Comfort Suites At WestGate Mall

10/10 Excellent
"The staff was very professional and the pool was very comfortable and Mia was very helpful."
Erick 2-night trip
Posted 4 hours ago
Comfort Suites At WestGate Mall

Find out more about Upstate South Carolina

Everything you need to know about Upstate South Carolina vacation rentals

Whether you’re excited for the perfect family vacation, a romantic getaway for two, or the ultimate city break, we’ve got the Upstate South Carolina vacation rental for you. At Expedia, you can take your pick from private vacation homes, apartments, condos, resorts, cabins, villas, motels. The list goes on, and on …and on.

There’s just as wide a choice of amenities, too. Maybe you’re dreaming of your own pool, long evenings in a hot tub, or watching the kids laugh through the day at a waterpark. Maybe you just want a quiet retreat in a pet-friendly apartment. Well, we can help you find it. Hunt out the perfect Upstate South Carolina vacation rental for you by simply entering your desired dates. Then check your favorite filters to narrow down your search.

Upstate South Carolina vacation rentals: An excellent choice for every season

Whenever you want to travel, a warm welcome awaits you in Upstate South Carolina. If you’re looking for a little peace, consider booking during the quieter low season months. For more hustle and bustle, you may prefer to visit Upstate South Carolina in high season.

Prices vary throughout the year. Your chosen location, property type, and amenities will impact the cost of your trip, too. The selection of properties we have chosen for you start as low as $69 per night. Rates vary depending on your travel dates, location, and amenities so make a search and you might find even better deals!

How to find incredible deals on Upstate South Carolina rentals

At Expedia, we put the best Upstate South Carolina vacation rentals in one place. All you need to do is take your pick. And as we offer book now, pay later options, as well as free cancellation on some properties, you can plan your trip with total peace of mind. You’ll always find a great deal with Expedia.

To find some top Upstate South Carolina rental deals, enter your travel dates, and sort your search results by price. You can also filter by budget, so you only see accommodation in your ballpark. Next, add any filters you want—and just like that, you’ve built your dream Upstate South Carolina vacation.

If you’re looking for a little inspiration, browse our latest incredible offers, or use the map to view all accommodation in and around Upstate South Carolina. And to unlock even more fantastic deals, bundle your accommodation, flights, and car rental together to save and book with Expedia in complete confidence.

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