
Upstate South Carolina Vacation Rentals
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Our top choices for Upstate South Carolina vacation rentals

1. Whiffletree Farmhouse just 2 mins off I-26 & 8 mins from downtown Spartanburg!
Whiffletree Farmhouse just 2 mins off I-26 & 8 mins from downtown Spartanburg!

3. Luxury modern container home in a rural setting! Pet friendly!
Luxury modern container home in a rural setting! Pet friendly!
4. Cozy cabin in the woods! Pets welcome!
Cozy cabin in the woods! Pets welcome!
7. Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy
Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy
8. ~2 Bedroom Cozy Gem 💎 5 minutes from Downtown Spartanburg~
~2 Bedroom Cozy Gem 💎 5 minutes from Downtown Spartanburg~Find vacation rentals that suit your style
Top Upstate South Carolina Hotel Reviews

Aloft by Marriott Greenville Downtown
Find out more about Upstate South Carolina
Everything you need to know about Upstate South Carolina vacation rentals
Whether you’re excited for the perfect family vacation, a romantic getaway for two, or the ultimate city break, we’ve got the Upstate South Carolina vacation rental for you. At Expedia, you can take your pick from private vacation homes, apartments, condos, resorts, cabins, villas, motels. The list goes on, and on …and on.
There’s just as wide a choice of amenities, too. Maybe you’re dreaming of your own pool, long evenings in a hot tub, or watching the kids laugh through the day at a waterpark. Maybe you just want a quiet retreat in a pet-friendly apartment. Well, we can help you find it. Hunt out the perfect Upstate South Carolina vacation rental for you by simply entering your desired dates. Then check your favorite filters to narrow down your search.
Upstate South Carolina vacation rentals: An excellent choice for every season
Whenever you want to travel, a warm welcome awaits you in Upstate South Carolina. If you’re looking for a little peace, consider booking during the quieter low season months. For more hustle and bustle, you may prefer to visit Upstate South Carolina in high season.
Prices vary throughout the year. Your chosen location, property type, and amenities will impact the cost of your trip, too. The selection of properties we have chosen for you start as low as $118 per night. Rates vary depending on your travel dates, location, and amenities so make a search and you might find even better deals!
How to find incredible deals on Upstate South Carolina rentals
At Expedia, we put the best Upstate South Carolina vacation rentals in one place. All you need to do is take your pick. And as we offer book now, pay later options, as well as free cancellation on some properties, you can plan your trip with total peace of mind. You’ll always find a great deal with Expedia.
To find some top Upstate South Carolina rental deals, enter your travel dates, and sort your search results by price. You can also filter by budget, so you only see accommodation in your ballpark. Next, add any filters you want—and just like that, you’ve built your dream Upstate South Carolina vacation.
If you’re looking for a little inspiration, browse our latest incredible offers, or use the map to view all accommodation in and around Upstate South Carolina. And to unlock even more fantastic deals, bundle your accommodation, flights, and car rental together to save and book with Expedia in complete confidence.
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- Flights from Philadelphia (PHL) to Greenville (GSP)
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- Routes Rental Cars in Upstate South Carolina
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- Car rental Spartanburg
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- Car rental Greenville
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