A bench, a bicycle, and a lake surrounded by trees.

Upstate South Carolina Vacation Rentals

  • Bundle & Save

    Get more, spend less whenever you see Bundle & Save deals

  • OneKeyCash

    Earn OneKeyCash on all your eligible bookings

  • Upfront pricing

    We are not like the others - we include taxes and fees

Check prices for these dates

In two weeks
Aug 21 - Aug 23
In two months
Oct 2 - Oct 4
In three months
Oct 30 - Nov 1
In four months
Nov 27 - Nov 29

Our top choices for Upstate South Carolina vacation rentals

Interior

1. Whiffletree Farmhouse just 2 mins off I-26 & 8 mins from downtown Spartanburg!

Whiffletree Farmhouse just 2 mins off I-26 & 8 mins from downtown Spartanburg!
Roebuck
10.0 out of 10, Exceptional, (40 reviews)
"Awesome farmhouse, will stay here again on future trips!"
United States
Jeremy C.
$252 nightly
The price is $280
Aug 10 - Aug 11
Total with taxes and fees
Whiffletree Farmhouse just 2 mins off I-26 & 8 mins from downtown Spartanburg!
Trailside Wedge Cottage | Terrace/patio

2. The Station by Compo Hotels

The Station by Compo Hotels
4.0 star property
Travelers Rest
10.0 out of 10, Exceptional, (23 reviews)
"Lovely place to stay. Very clean and well appointed. The host was responsive and welcoming. Comfortable bed and quiet. Highly recommend."
United States
Anne
$319 nightly
The price is $351
Aug 4 - Aug 5
Total with taxes and fees
The Station by Compo Hotels
Terrace/patio

3. Luxury modern container home in a rural setting! Pet friendly!

Luxury modern container home in a rural setting! Pet friendly!
Enoree
9.2 out of 10, Wonderful, (11 reviews)
"Great communication! "
United States
Susan F.
$163 nightly
The price is $180
Aug 7 - Aug 8
Total with taxes and fees
Luxury modern container home in a rural setting! Pet friendly!
Terrace/patio

4. Cozy cabin in the woods! Pets welcome!

Cozy cabin in the woods! Pets welcome!
Enoree
9.6 out of 10, Exceptional, (11 reviews)
"This was a perfect little stay for myself, my husband and our two pups! It was off the beaten path, but still felt very safe."
United States
Christina H.
$167 nightly
The price is $185
Aug 4 - Aug 5
Total with taxes and fees
Cozy cabin in the woods! Pets welcome!
Premium bedding, in-room safe, laptop workspace, WiFi (free)

5. Carolina Camp Cedar

Carolina Camp Cedar
3.5 star property
Pickens
10.0 out of 10, Exceptional, (3 reviews)
"The cottage was clean, staff was so friendly, our stay was quiet and peaceful… it was perfect! Definitely planning to stay there again!"
United States
Katlynn
$236 nightly
The price is $262
Sep 3 - Sep 4
Total with taxes and fees
Carolina Camp Cedar
1 bedroom, WiFi

6. Patriot Point A

Patriot Point A
Roebuck
10.0 out of 10, Exceptional, (27 reviews)
"The host was very welcoming and the property was nice. "
United States
Jordan R.
$145 nightly
The price is $161
Aug 15 - Aug 16
Total with taxes and fees
Patriot Point A
View from property

7. Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy

Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy
2.0 star property
Seneca
9.8 out of 10, Exceptional, (93 reviews)
"Cabin very cozy, pet friendly… great place to be disconnected for a couple days!! "
United States
LUIS EDUARDO
$124 nightly
The price is $136
Sep 2 - Sep 3
Total with taxes and fees
Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy
Exterior

8. ~2 Bedroom Cozy Gem 💎 5 minutes from Downtown Spartanburg~

~2 Bedroom Cozy Gem 💎 5 minutes from Downtown Spartanburg~
Spartanburg
10.0 out of 10, Exceptional, (56 reviews)
"Quiet neighborhood. Beautiful yard!"
United States
David C.
$192 nightly
The price is $213
Aug 23 - Aug 24
Total with taxes and fees
~2 Bedroom Cozy Gem 💎 5 minutes from Downtown Spartanburg~
Living area

9. Adorable Upscale cottage in Downtown Fountain Inn.

Adorable Upscale cottage in Downtown Fountain Inn.
Fountain Inn
10.0 out of 10, Exceptional, (44 reviews)
"Really beautiful place, loved that it was dog friendly."
United States
Pam C.
$226 nightly
The price is $249
Aug 4 - Aug 5
Total with taxes and fees
Adorable Upscale cottage in Downtown Fountain Inn.
Deluxe Two Bedroom (Self Check-in with Virtual Front Desk) | Living area | 55-inch flat-screen TV with digital channels, TV, streaming services

10. Mint House Greenville Downtown by Kasa

Mint House Greenville Downtown by Kasa
4.0 star property
Greenville Downtown
9.2 out of 10, Wonderful, (864 reviews)
"We had a great time, very close to eating and shopping. The amenities were very helpful and we felt the area was very safe. We had an issue with getting a ticket even though we paid for parking but it was taken care of within an hour!"
United States
Robin
$107 nightly
The price is $118
Aug 31 - Sep 1
Total with taxes and fees
Mint House Greenville Downtown by Kasa
Outdoor spa tub

11. ⭐️Hot Tub⭐️ Luxury Getaway Near GSP Airport Downtown Greer Greenville Spartanburg

⭐️Hot Tub⭐️ Luxury Getaway Near GSP Airport Downtown Greer Greenville Spartanburg
Lyman
10.0 out of 10, Exceptional, (44 reviews)
"2nd time staying, great place."
United States
DAWN M.
$207 nightly
The price is $230
Aug 4 - Aug 5
Total with taxes and fees
⭐️Hot Tub⭐️ Luxury Getaway Near GSP Airport Downtown Greer Greenville Spartanburg
Coffee/tea maker, fridge, microwave, oven

12. Fairview Luxury Oasis

Fairview Luxury Oasis
Spartanburg
10.0 out of 10, Exceptional, (31 reviews)
"Great place to stay! We loved it!"
United States
John E.
$375 nightly
The price is $416
Aug 17 - Aug 18
Total with taxes and fees
Fairview Luxury Oasis
TV

13. Southern Charm Townhome

Southern Charm Townhome
Simpsonville
9.8 out of 10, Exceptional, (8 reviews)
"Very clean and safe location. Super cute interior decorations and comfortable. Also a great location for us to visit family who are local. Absolutely would stay again."
United States
Brianna F.
$354 nightly
The price is $402
Aug 4 - Aug 5
Total with taxes and fees
Southern Charm Townhome
Terrace/patio

14. NEW - Heated Pool - Hot Tub - Game Room - Sauna - 20 Mins to GVL

NEW - Heated Pool - Hot Tub - Game Room - Sauna - 20 Mins to GVL
Greer
10.0 out of 10, Exceptional, (58 reviews)
"We enjoyed our stay. The house is very well stocked with everything you need during your stay. It was perfect for a family visit."
United States
Frank S.
NEW - Heated Pool - Hot Tub - Game Room - Sauna - 20 Mins to GVL
Smart TV

15. Updated Cottage Steps from Everything Downtown

Updated Cottage Steps from Everything Downtown
Greenville Downtown
10.0 out of 10, Exceptional, (38 reviews)
"Great location."
United States
Christopher H.
$394 nightly
The price is $433
Aug 4 - Aug 5
Total with taxes and fees
Updated Cottage Steps from Everything Downtown
Coffee/tea maker, fridge, microwave, oven

16. Luxury 6,000+ sq ft Hideaway with Heated Pool, Spa, & Sauna - near Greenville

Luxury 6,000+ sq ft Hideaway with Heated Pool, Spa, & Sauna - near Greenville
Taylors
10.0 out of 10, Exceptional, (18 reviews)
"Great stay! Awesome house, lots of fun. "
United States
Mitch P.
$927 nightly
The price is $980
Aug 30 - Aug 31
Total with taxes and fees
Luxury 6,000+ sq ft Hideaway with Heated Pool, Spa, & Sauna - near Greenville
2 bedrooms, WiFi (free), bed sheets

17. Nice 2 BR Spartanburg Townhouse Near BMW,GSP Airport,Milliken,Downtown, All HWYs

Nice 2 BR Spartanburg Townhouse Near BMW,GSP Airport,Milliken,Downtown, All HWYs
Spartanburg
Nice 2 BR Spartanburg Townhouse Near BMW,GSP Airport,Milliken,Downtown, All HWYs
Coffee/tea maker, fridge, microwave, oven

18. The Blue Bungalow by Unity Park - Newly Renovated

The Blue Bungalow by Unity Park - Newly Renovated
Woodside Cotton Mill Village Historic District
9.8 out of 10, Exceptional, (103 reviews)
$200 nightly
The price is $220
Aug 5 - Aug 6
Total with taxes and fees
The Blue Bungalow by Unity Park - Newly Renovated
Exterior detail

19. Riverwalk Falls-lovely one bedroom condo

Riverwalk Falls-lovely one bedroom condo
Greenville Downtown
10.0 out of 10, Exceptional, (191 reviews)
"Parking is close. The place is clean and comfortable. "
United States
Michael K.
$255 nightly
The price is $281
Aug 11 - Aug 12
Total with taxes and fees
Riverwalk Falls-lovely one bedroom condo
Interior

20. STRATHAM STATION: 4Bd/2.5Ba in Downtown Greenville, SC

STRATHAM STATION: 4Bd/2.5Ba in Downtown Greenville, SC
Greenville
9.8 out of 10, Exceptional, (63 reviews)
"Prefect location for our event we were attending. Super clean and beds were comfortable for all! "
United States
pam s.
$387 nightly
The price is $425
Aug 4 - Aug 5
Total with taxes and fees
STRATHAM STATION: 4Bd/2.5Ba in Downtown Greenville, SC
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free

Top Upstate South Carolina Hotel Reviews

Aloft by Marriott Greenville Downtown

Aloft by Marriott Greenville Downtown

10/10 Excellent
"The amenities of the Pool, are not what the pictures are. Pool is super small, like for Kids, and Pool deck area as well. Decided to not get in and just go walk instead of having a pool day. Location thou is great! highly recommended. Is right on the strip were you can walk any direction and is close to all the restaurants and the Heart of Downtown Greenville."
AIMEE 1-night trip
Posted 4 hours ago
Aloft by Marriott Greenville Downtown

Find out more about Upstate South Carolina

Everything you need to know about Upstate South Carolina vacation rentals

Whether you’re excited for the perfect family vacation, a romantic getaway for two, or the ultimate city break, we’ve got the Upstate South Carolina vacation rental for you. At Expedia, you can take your pick from private vacation homes, apartments, condos, resorts, cabins, villas, motels. The list goes on, and on …and on.

There’s just as wide a choice of amenities, too. Maybe you’re dreaming of your own pool, long evenings in a hot tub, or watching the kids laugh through the day at a waterpark. Maybe you just want a quiet retreat in a pet-friendly apartment. Well, we can help you find it. Hunt out the perfect Upstate South Carolina vacation rental for you by simply entering your desired dates. Then check your favorite filters to narrow down your search.

Upstate South Carolina vacation rentals: An excellent choice for every season

Whenever you want to travel, a warm welcome awaits you in Upstate South Carolina. If you’re looking for a little peace, consider booking during the quieter low season months. For more hustle and bustle, you may prefer to visit Upstate South Carolina in high season.

Prices vary throughout the year. Your chosen location, property type, and amenities will impact the cost of your trip, too. The selection of properties we have chosen for you start as low as $118 per night. Rates vary depending on your travel dates, location, and amenities so make a search and you might find even better deals!

How to find incredible deals on Upstate South Carolina rentals

At Expedia, we put the best Upstate South Carolina vacation rentals in one place. All you need to do is take your pick. And as we offer book now, pay later options, as well as free cancellation on some properties, you can plan your trip with total peace of mind. You’ll always find a great deal with Expedia.

To find some top Upstate South Carolina rental deals, enter your travel dates, and sort your search results by price. You can also filter by budget, so you only see accommodation in your ballpark. Next, add any filters you want—and just like that, you’ve built your dream Upstate South Carolina vacation.

If you’re looking for a little inspiration, browse our latest incredible offers, or use the map to view all accommodation in and around Upstate South Carolina. And to unlock even more fantastic deals, bundle your accommodation, flights, and car rental together to save and book with Expedia in complete confidence.

Explore a world of travel with Expedia