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Upstate South Carolina Vacation Rentals

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Vacation Rentals in Upstate South Carolina

Two Bedroom Suite | 3 bedrooms, laptop workspace, iron/ironing board, free WiFi
Mint House Greenville - Downtown

Mint House Greenville - Downtown

4.0 star property
Greenville Downtown
9.2 out of 10, Wonderful, (769)
"Excellent stay as always! "
United States
Elena
$118 nightly
The price is $129
Dec 22 - Dec 23
Total with taxes and fees
Mint House Greenville - Downtown
1 bedroom, individually furnished, desk, laptop workspace
stayAPT Suites Greenville-Haywood Mall

stayAPT Suites Greenville-Haywood Mall

3.0 star property
Greenville
9.2 out of 10, Wonderful, (192)
"Great place!"
United States
Daecia
$119 nightly
The price is $131
Dec 1 - Dec 2
Total with taxes and fees
stayAPT Suites Greenville-Haywood Mall
Exterior
Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy

Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy

2.0 star property
Seneca
9.8 out of 10, Exceptional, (46)
"The place was absolutely magnificent."
United States
David
$116 nightly
The price is $127
Dec 1 - Dec 2
Total with taxes and fees
Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy
Cottage (1 Bedroom) | Exterior
Wooded Cottage - 3 Mi to Clemson University

Wooded Cottage - 3 Mi to Clemson University

3.0 star property
Clemson
10.0 out of 10, Exceptional, (1)
Wooded Cottage - 3 Mi to Clemson University
2 bedrooms, free WiFi, bed sheets
Stylish Downtown Greenville Apartment 1 Block Off Main Street

Stylish Downtown Greenville Apartment 1 Block Off Main Street

2.0 star property
Greenville Downtown
9.2 out of 10, Wonderful, (5)
$139 nightly
The price is $153
Dec 3 - Dec 4
Total with taxes and fees
Stylish Downtown Greenville Apartment 1 Block Off Main Street
Apartment, 2 Bedrooms | Living area | 40-inch TV with digital channels
Park Place Apartments by Landing

Park Place Apartments by Landing

4.0 star property
Greenville
7.6 out of 10, Good, (41)
"Great place for a different experience Enjoyed the train "
United States
Edward
Park Place Apartments by Landing
Trailside Wedge Cottage | Terrace/patio
The Station by Compo Hotels

The Station by Compo Hotels

4.0 star property
Travelers Rest
10.0 out of 10, Exceptional, (15)
"great place perfect for more privacy vs. a standard hotel"
United States
John
$282 nightly
The price is $311
Dec 1 - Dec 2
Total with taxes and fees
The Station by Compo Hotels
Fridge, microwave, oven, stovetop
Stylish Downtown Greenville Apartment 1 Block Off Main Street

Stylish Downtown Greenville Apartment 1 Block Off Main Street

2.0 star property
Greenville Downtown
10.0 out of 10, Exceptional, (3)
"Very convenient and walkable to downtown restaurants and activities. Very clean and unique as a remodeled older home in a historic neighborhood."
United States
Brad P.
$131 nightly
The price is $144
Nov 25 - Nov 26
Total with taxes and fees
Stylish Downtown Greenville Apartment 1 Block Off Main Street
Standard Cabin, Courtyard View | Premium bedding, in-room safe, laptop workspace, free WiFi
Carolina Camp Cedar

Carolina Camp Cedar

3.5 star property
Pickens
$175 nightly
The price is $194
Nov 30 - Dec 1
Total with taxes and fees
Carolina Camp Cedar
Outdoor dining
Riverwalk Falls-lovely one bedroom condo

Riverwalk Falls-lovely one bedroom condo

Greenville Downtown
10.0 out of 10, Exceptional, (172)
"An amazing location and great stay!"
United States
Amanda S.
$186 nightly
The price is $205
Nov 30 - Dec 1
Total with taxes and fees
Riverwalk Falls-lovely one bedroom condo
Fridge, microwave, oven, stovetop
Adorable & recently renovated condo within walking distance to downtown Clemson.

Adorable & recently renovated condo within walking distance to downtown Clemson.

Clemson
10.0 out of 10, Exceptional, (27)
"Clean, quiet, newly renovated. Exactly what we needed for a relaxing weekend. "
United States
Daniel
Adorable & recently renovated condo within walking distance to downtown Clemson.
Property grounds
Location, Location! Five Forks area: Simpsonville, Greenville, Greer, Mauldin

Location, Location! Five Forks area: Simpsonville, Greenville, Greer, Mauldin

Simpsonville
10.0 out of 10, Exceptional, (10)
"Just a beautiful — and beautifully decorated — little home in a fantastic location. Had everything we needed and the owners were super-kind. Loved it!"
United States
Katherine J.
Location, Location! Five Forks area: Simpsonville, Greenville, Greer, Mauldin
Exterior
Historic 19th Century Cabin in Greenville

Historic 19th Century Cabin in Greenville

Greenville
10.0 out of 10, Exceptional, (4)
"Great cabin in the perfect location. Hosts have thought of everything. Will definitely stay here again! "
United States
David R.
$146 nightly
The price is $161
Nov 26 - Nov 27
Total with taxes and fees
Historic 19th Century Cabin in Greenville
Fridge, microwave, oven, stovetop
Perfect Lake Hartwell Getaway - Gorgeous Lake Views!

Perfect Lake Hartwell Getaway - Gorgeous Lake Views!

Seneca
9.8 out of 10, Exceptional, (99)
"Our whole family had a great stay. "
United States
Cameron M.
Perfect Lake Hartwell Getaway - Gorgeous Lake Views!
Fridge, microwave, oven, stovetop
Beautiful Home Close To Everything

Beautiful Home Close To Everything

Greenville
9.6 out of 10, Exceptional, (169)
"Loved the house! Great location. Fun back yard. Has everything you need for a family to have a great time. Owner is very communicative which makes the experience so much better. "
United States
Nik S.
$243 nightly
The price is $268
Dec 1 - Dec 2
Total with taxes and fees
Beautiful Home Close To Everything
Fridge, microwave, oven, stovetop
Great Getaway

Great Getaway

Clemson
10.0 out of 10, Exceptional, (22)
"Lovely, quiet and spacious yet still walkable to campus."
United States
amy
Great Getaway
Private kitchen
Downtown Easley Home

Downtown Easley Home

Easley
7.6 out of 10, Good, (5)
"The house was great for our one night stay. The house was clean and stocked. We had to leave early and didn't spend the entire night. But the host was gracious and easy to communicate with. Would recommend!"
United States
CANDY B.
$213 nightly
The price is $237
Nov 25 - Nov 26
Total with taxes and fees
Downtown Easley Home
Dining
Charming 2-bedroom cabin in beautiful Mountain Rest on Lake Becky

Charming 2-bedroom cabin in beautiful Mountain Rest on Lake Becky

Mountain Rest
9.6 out of 10, Exceptional, (7)
"Nice pet friendly cabin on the lake. Communication was excellent. We were very pleased."
United States
Lisa
$246 nightly
The price is $271
Nov 25 - Nov 26
Total with taxes and fees
Charming 2-bedroom cabin in beautiful Mountain Rest on Lake Becky
Terrace/patio
4 Bedroom Bungalow Minutes from Downtown Greenville

4 Bedroom Bungalow Minutes from Downtown Greenville

Overbrook Historic District
10.0 out of 10, Exceptional, (34)
"Property was beautifully appointed and host was super easy to work with!"
United States
Mary W.
4 Bedroom Bungalow Minutes from Downtown Greenville
Exterior detail
Deep Water-Keowee Lakefront,Kayaks, Dock, Dog friendly,level water entry, kayaks

Deep Water-Keowee Lakefront,Kayaks, Dock, Dog friendly,level water entry, kayaks

Seneca
9.8 out of 10, Exceptional, (63)
"Wonderful experience! Great home, location and host."
United States
Christine V.
Deep Water-Keowee Lakefront,Kayaks, Dock, Dog friendly,level water entry, kayaks
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Upstate South Carolina Hotel Reviews

Comfort Suites Greenville Airport

Comfort Suites Greenville Airport

10/10 Excellent
"Room was spotless. Staff was very friendly, breakfast was great. Only one little issue we had. The following we went out, when we got back to the room the AC had a fishy smell coming from it which kind of weird but after a while it was ok. We had a short stay but it great. I would use them again."
Lisa 2-night trip
Posted 1 day ago
Comfort Suites Greenville Airport

Find out more about Upstate South Carolina

Everything you need to know about Upstate South Carolina vacation rentals

Whether you’re excited for the perfect family vacation, a romantic getaway for two, or the ultimate city break, we’ve got the Upstate South Carolina vacation rental for you. At Expedia, you can take your pick from private vacation homes, apartments, condos, resorts, cabins, villas, motels. The list goes on, and on …and on.

There’s just as wide a choice of amenities, too. Maybe you’re dreaming of your own pool, long evenings in a hot tub, or watching the kids laugh through the day at a waterpark. Maybe you just want a quiet retreat in a pet-friendly apartment. Well, we can help you find it. Hunt out the perfect Upstate South Carolina vacation rental for you by simply entering your desired dates. Then check your favorite filters to narrow down your search.

Upstate South Carolina vacation rentals: An excellent choice for every season

Whenever you want to travel, a warm welcome awaits you in Upstate South Carolina. If you’re looking for a little peace, consider booking during the quieter low season months. For more hustle and bustle, you may prefer to visit Upstate South Carolina in high season.

Prices vary throughout the year. Your chosen location, property type, and amenities will impact the cost of your trip, too. The selection of properties we have chosen for you start as low as $127 per night. Rates vary depending on your travel dates, location, and amenities so make a search and you might find even better deals!

How to find incredible deals on Upstate South Carolina rentals

At Expedia, we put the best Upstate South Carolina vacation rentals in one place. All you need to do is take your pick. And as we offer book now, pay later options, as well as free cancellation on some properties, you can plan your trip with total peace of mind. You’ll always find a great deal with Expedia.

To find some top Upstate South Carolina rental deals, enter your travel dates, and sort your search results by price. You can also filter by budget, so you only see accommodation in your ballpark. Next, add any filters you want—and just like that, you’ve built your dream Upstate South Carolina vacation.

If you’re looking for a little inspiration, browse our latest incredible offers, or use the map to view all accommodation in and around Upstate South Carolina. And to unlock even more fantastic deals, bundle your accommodation, flights, and car rental together to save and book with Expedia in complete confidence.

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