Title: Upstate South Carolina Vacation Rentals from $116: Search Short-Term Rentals | Expedia.com [Upstate South Carolina Travel Guide](https://expedia.com/Upstate-South-Carolina.dx553248635975748552)[Hotels in Upstate South Carolina](https://expedia.com/Upstate-South-Carolina-Hotels.d553248635975748552.Travel-Guide-Hotels)[Flights to Upstate South Carolina](https://expedia.com/Cheap-Flights-To-Upstate-South-Carolina.d553248635975748552.Travel-Guide-Flights)[Things to do in Upstate South Carolina](https://expedia.com/Things-To-Do-In-Upstate-South-Carolina.d553248635975748552.Travel-Guide-Activities)[Car Rentals in Upstate South Carolina](https://expedia.com/Car-Rentals-In-Upstate-South-Carolina.d553248635975748552.Car-Rental-Guide)[Upstate South Carolina Vacation Packages](https://expedia.com/Upstate-South-Carolina.d553248635975748552.Destination-Travel-Guides) ![It is only a 1 mile hike to this beauty. View a video about it here: https://www.hdcarolina.com/episode/riley-moore-falls #Waterfall](https://images.trvl-media.com/place/6122927/69b8ebaa-53a3-428e-ba53-37ac2de11862.jpg?impolicy=fcrop&w=1200&h=500&q=medium) Photo by Ryan Watts ![](https://images.trvl-media.com/place/6122927/69b8ebaa-53a3-428e-ba53-37ac2de11862.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light_bundle_and_save.svg) ### Bundle & Save Get more, spend less whenever you see Bundle & Save deals - ![](https://a.travel-assets.com/travel-assets-manager/pictograms-expedia/light__onekey.svg) ### OneKeyCash Earn OneKeyCash on all your eligible bookings - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light_ftc.svg) ### Upfront pricing We are not like the others - we include taxes and fees ## Check prices for these dates In two weeks [Apr 3 - Apr 5](https://www.expedia.com/Hotel-Search?regionId=553248635975748552&startDate=2026-04-03&endDate=2026-04-05&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two months [May 15 - May 17](https://www.expedia.com/Hotel-Search?regionId=553248635975748552&startDate=2026-05-15&endDate=2026-05-17&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In three months [Jun 12 - Jun 14](https://www.expedia.com/Hotel-Search?regionId=553248635975748552&startDate=2026-06-12&endDate=2026-06-14&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In four months [Jul 10 - Jul 12](https://www.expedia.com/Hotel-Search?regionId=553248635975748552&startDate=2026-07-10&endDate=2026-07-12&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Our top choices for Upstate South Carolina vacation rentals ![View from property](https://images.trvl-media.com/lodging/111000000/110490000/110487400/110487306/d7c06df6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Shower, towels, soap, shampoo](https://images.trvl-media.com/lodging/111000000/110490000/110487400/110487306/cf119645.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Cabin, 1 Queen Bed (View) | Private kitchen | Mini-fridge, stovetop, cookware/dishes/utensils, paper towels](https://images.trvl-media.com/lodging/111000000/110490000/110487400/110487306/60991646.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, desk, laptop workspace, bed sheets](https://images.trvl-media.com/lodging/111000000/110490000/110487400/110487306/f29b16c6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Cabin in Seneca [](https://www.expedia.com/Postcard-Cabins-Lake-Hartwell.h110487306.Hotel-Information) 9.8/10 Exceptional (66 reviews) "Excellent stay." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Beonca $139 nightly $153 total Mar 22 - Mar 23 Total with taxes and fees [](https://www.expedia.com/Postcard-Cabins-Lake-Hartwell.h110487306.Hotel-Information) ![Premium bedding, in-room safe, individually furnished, laptop workspace](https://images.trvl-media.com/lodging/123000000/122100000/122099800/122099740/afe0f510.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, in-room safe, individually furnished, laptop workspace](https://images.trvl-media.com/lodging/123000000/122100000/122099800/122099740/4d5d913d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Cabin, 1 Bedroom, Courtyard View | Living area | 55-inch Smart TV with digital channels, streaming services](https://images.trvl-media.com/lodging/123000000/122100000/122099800/122099740/3f2de599.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Seasonal outdoor pool, open 7:00 AM to 10:00 PM, pool umbrellas](https://images.trvl-media.com/lodging/123000000/122100000/122099800/122099740/b26b87ac.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Cabin in Pickens [](https://www.expedia.com/Pickens-Hotels-Carolina-Camp-Cedar.h122099740.Hotel-Information) 10/10 Exceptional (3 reviews) "The cottage was clean, staff was so friendly, our stay was quiet and peaceful… it was perfect! Definitely planning to stay there again!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Katlynn $170 nightly $189 total Mar 22 - Mar 23 Total with taxes and fees [](https://www.expedia.com/Pickens-Hotels-Carolina-Camp-Cedar.h122099740.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/96000000/95310000/95305700/95305698/51159ba6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/96000000/95310000/95305700/95305698/e35ebf2a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV, DVD player](https://images.trvl-media.com/lodging/96000000/95310000/95305700/95305698/02ce48d2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/96000000/95310000/95305700/95305698/a4ea3c70.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Apartment in Landrum [](https://www.expedia.com/Landrum-Hotels-Private-Apartment-On-Beautiful-Grounds.h95305698.Hotel-Information) 9.8/10 Exceptional (35 reviews) "We loved our stay here! Friendly hosts, clean space, great location and their cute kitty Luna even stopped by one evening for a visit which I loved! Highly recommend staying here " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Cassidy W. $148 nightly $164 total Mar 21 - Mar 22 Total with taxes and fees [](https://www.expedia.com/Landrum-Hotels-Private-Apartment-On-Beautiful-Grounds.h95305698.Hotel-Information) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/79000000/78140000/78137300/78137271/ff8281c0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/79000000/78140000/78137300/78137271/370e1a1e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Dining](https://images.trvl-media.com/lodging/79000000/78140000/78137300/78137271/88b08b4b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/79000000/78140000/78137300/78137271/245dc985.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Vacation Home in Woodside Cotton Mill Village Historic District [](https://www.expedia.com/Greenville-Hotels-The-Blue-Bungalow-By-Unity-Park-Newly-Renovated.h78137271.Hotel-Information) 9.8/10 Exceptional (89 reviews) "The house was super clean and nice! The host was awesome. We thoroughly enjoyed our stay. Convenient to everything. We will definitely stay again!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Lisa $199 nightly $219 total Mar 22 - Mar 23 Total with taxes and fees [](https://www.expedia.com/Greenville-Hotels-The-Blue-Bungalow-By-Unity-Park-Newly-Renovated.h78137271.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/118000000/117970000/117968000/117967992/6856c3ec.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/118000000/117970000/117968000/117967992/30352fd0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV, fireplace](https://images.trvl-media.com/lodging/118000000/117970000/117968000/117967992/04ddac11.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/118000000/117970000/117968000/117967992/c148f208.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Cabin in Greenville [](https://www.expedia.com/Greenville-Hotels-Historic-19th-Century-Cabin-In-Greenville.h117967992.Hotel-Information) 9.8/10 Exceptional (7 reviews) "unique ,cozy cabin!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Martha G. $146 nightly $161 total Mar 23 - Mar 24 Total with taxes and fees [](https://www.expedia.com/Greenville-Hotels-Historic-19th-Century-Cabin-In-Greenville.h117967992.Hotel-Information) ![Terrace/patio](https://images.trvl-media.com/lodging/107000000/106270000/106262900/106262845/38d59f5d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV, DVD player, books, music library](https://images.trvl-media.com/lodging/107000000/106270000/106262900/106262845/30f87e34.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/107000000/106270000/106262900/106262845/1483dace.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior detail](https://images.trvl-media.com/lodging/107000000/106270000/106262900/106262845/f7117701.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Cabin in Enoree [](https://www.expedia.com/Enoree-Hotels-Cozy-Cabin-In-The-Woods-Pets-Welcome.h106262845.Hotel-Information) 10/10 Exceptional (8 reviews) "Location felt private, yet was close to the highway. Cute little cabin." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Lindsay C. $167 nightly $185 total Mar 25 - Mar 26 Total with taxes and fees [](https://www.expedia.com/Enoree-Hotels-Cozy-Cabin-In-The-Woods-Pets-Welcome.h106262845.Hotel-Information) ![Outdoor spa tub](https://images.trvl-media.com/lodging/77000000/76930000/76929000/76928997/de87b393.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/77000000/76930000/76929000/76928997/5e6e3f5b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, free WiFi, bed sheets](https://images.trvl-media.com/lodging/77000000/76930000/76929000/76928997/394f1525.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/77000000/76930000/76929000/76928997/w945h710x0y32-a770d4e0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Cabin in Pickens [](https://www.expedia.com/Pickens-Hotels-Lazy-Bear-Retreat-By-The-Creek.h76928997.Hotel-Information) 10/10 Exceptional (52 reviews) "What a beautiful little getaway! Great communication with owner, easy to find the location and entry. Everything was very clean and working as it should. Loved the hot tub." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Molly $166 nightly $184 total Mar 23 - Mar 24 Total with taxes and fees [](https://www.expedia.com/Pickens-Hotels-Lazy-Bear-Retreat-By-The-Creek.h76928997.Hotel-Information) ![Property grounds](https://images.trvl-media.com/lodging/67000000/66030000/66026900/66026894/efec02d1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV, table tennis](https://images.trvl-media.com/lodging/67000000/66030000/66026900/66026894/1a5c9883.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV, table tennis](https://images.trvl-media.com/lodging/67000000/66030000/66026900/66026894/ad2b1b86.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior detail](https://images.trvl-media.com/lodging/67000000/66030000/66026900/66026894/69fcdbfb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Cabin in Pickens [](https://www.expedia.com/Pickens-Hotels-Luxury-Vacation-Mtn-Home.h66026894.Hotel-Information) 9.8/10 Exceptional (26 reviews) "Everything was perfect from the hot tub to the comfort of the beds!!!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Kelly C. $297 nightly $329 total Mar 22 - Mar 23 Total with taxes and fees [](https://www.expedia.com/Pickens-Hotels-Luxury-Vacation-Mtn-Home.h66026894.Hotel-Information) ![1 bedroom, free WiFi, bed sheets](https://images.trvl-media.com/lodging/81000000/80940000/80930400/80930381/9a8d8ddd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/81000000/80940000/80930400/80930381/cfa62905.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Dining](https://images.trvl-media.com/lodging/81000000/80940000/80930400/80930381/a6933580.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV](https://images.trvl-media.com/lodging/81000000/80940000/80930400/80930381/8bccb626.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Cabin in Cleveland [](https://www.expedia.com/Cleveland-Hotels-Modern-Cabin-Near-Table-RockPretty-Place.h80930381.Hotel-Information) 10/10 Exceptional (70 reviews) "We had all we needed in the kitchen and enjoyed our meals in the sunroom. The cabin was perfect! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jay P. $200 nightly $220 total Mar 23 - Mar 24 Total with taxes and fees [](https://www.expedia.com/Cleveland-Hotels-Modern-Cabin-Near-Table-RockPretty-Place.h80930381.Hotel-Information) ![Private kitchen](https://images.trvl-media.com/lodging/99000000/98530000/98527500/98527491/w715h535x173y8-4b719005.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/99000000/98530000/98527500/98527491/dc9366b5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 bedrooms, iron/ironing board, WiFi, bed sheets](https://images.trvl-media.com/lodging/99000000/98530000/98527500/98527491/5ce41bd7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/99000000/98530000/98527500/98527491/0bea6995.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Apartment in Greenville [](https://www.expedia.com/Greenville-Hotels-2BR-Cedar-Lane-Road-Retreat-At-Swamp-Rabbit-Trail.h98527491.Hotel-Information) 9.6/10 Exceptional (26 reviews) "Good little place, comfortable. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jonathan P. $155 nightly $171 total Mar 22 - Mar 23 Total with taxes and fees [](https://www.expedia.com/Greenville-Hotels-2BR-Cedar-Lane-Road-Retreat-At-Swamp-Rabbit-Trail.h98527491.Hotel-Information) ![Trailside Wedge Cottage | Terrace/patio](https://images.trvl-media.com/lodging/89000000/88370000/88362000/88361952/346fcb37.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/89000000/88370000/88362000/88361952/87440d66.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Trailside Wedge Cottage | Living area | Smart TV](https://images.trvl-media.com/lodging/89000000/88370000/88362000/88361952/f19cdb36.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Vista Wedge Cottage | Private kitchen | Full-size fridge, microwave, dishwasher, coffee/tea maker](https://images.trvl-media.com/lodging/89000000/88370000/88362000/88361952/9304eefe.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Aparthotel in Travelers Rest [](https://www.expedia.com/Travelers-Rest-Hotels-The-Station-By-Compo-Hotels.h88361952.Hotel-Information) 10/10 Exceptional (17 reviews) "great place perfect for more privacy vs. a standard hotel" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) John $289 nightly $318 total Mar 22 - Mar 23 Total with taxes and fees [](https://www.expedia.com/Travelers-Rest-Hotels-The-Station-By-Compo-Hotels.h88361952.Hotel-Information) ![Sauna](https://images.trvl-media.com/lodging/115000000/114810000/114805200/114805191/w1284h1856x0y1-5421e5b7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, in-room safe, WiFi, bed sheets](https://images.trvl-media.com/lodging/115000000/114810000/114805200/114805191/8c57b2cf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/115000000/114810000/114805200/114805191/02b206f0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/115000000/114810000/114805200/114805191/611c0f59.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Cabin in Travelers Rest [](https://www.expedia.com/Travelers-Rest-Hotels-Unit-9-Beautiful-Bell-Tent-With-AC-And-WiFi-In-Travelers-Rest.h114805191.Hotel-Information) 10/10 Exceptional (3 reviews) "Hot tub, sauna and cold plunge are really nice. Bathrooms are clean and nice. I was able to work remotely in their clubhouse with fast internet. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Dustin W. $182 nightly $200 total Mar 21 - Mar 22 Total with taxes and fees [](https://www.expedia.com/Travelers-Rest-Hotels-Unit-9-Beautiful-Bell-Tent-With-AC-And-WiFi-In-Travelers-Rest.h114805191.Hotel-Information) ![Outdoor dining](https://images.trvl-media.com/lodging/108000000/107170000/107165600/107165576/561f96a3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 bedrooms, WiFi, bed sheets](https://images.trvl-media.com/lodging/108000000/107170000/107165600/107165576/5b5c70f9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/108000000/107170000/107165600/107165576/eb6bc512.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/108000000/107170000/107165600/107165576/0f0a6ac9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Cottage in Walhalla [](https://www.expedia.com/Walhalla-Hotels-Rainyville-Emerald-Charming-Cottage-With-Loft-In-Walhalla.h107165576.Hotel-Information) 10/10 Exceptional (11 reviews) "Perfect home away from home. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Christine $261 nightly $287 total Mar 22 - Mar 23 Total with taxes and fees [](https://www.expedia.com/Walhalla-Hotels-Rainyville-Emerald-Charming-Cottage-With-Loft-In-Walhalla.h107165576.Hotel-Information) ![Interior](https://images.trvl-media.com/lodging/100000000/99950000/99942200/99942155/0fa322d0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 bedrooms, desk, travel crib, WiFi](https://images.trvl-media.com/lodging/100000000/99950000/99942200/99942155/6ea9c430.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![TV](https://images.trvl-media.com/lodging/100000000/99950000/99942200/99942155/66271ed2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/100000000/99950000/99942200/99942155/43fd0878.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Apartment in Clemson [](https://www.expedia.com/Clemson-Hotels-Ballgame-Bungalow.h99942155.Hotel-Information) 9.0/10 Wonderful (10 reviews) "We had a great stay in this clean and centrally located two bedroom place - including quick communication with the property managers when we had some problems with the WiFi! Loved the location, will absolutely visit again. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Agatha L. $346 nightly $372 total Mar 21 - Mar 22 Total with taxes and fees [](https://www.expedia.com/Clemson-Hotels-Ballgame-Bungalow.h99942155.Hotel-Information) ![Outdoor dining](https://images.trvl-media.com/lodging/79000000/78180000/78175700/78175602/8f898e31.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/79000000/78180000/78175700/78175602/38a9f184.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Children's area](https://images.trvl-media.com/lodging/79000000/78180000/78175700/78175602/dc675269.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/79000000/78180000/78175700/78175602/9e7a83c0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Vacation Home in Marietta [](https://www.expedia.com/Marietta-Hotels-Hobbit-Hideaway-Do-Something-Different.h78175602.Hotel-Information) 10/10 Exceptional (54 reviews) "Very well appointed." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Sara P. $143 nightly $157 total Mar 25 - Mar 26 Total with taxes and fees [](https://www.expedia.com/Marietta-Hotels-Hobbit-Hideaway-Do-Something-Different.h78175602.Hotel-Information) ![Signature Cottage, 2 Bedrooms | Living room | 43-inch Smart TV with cable channels, TV, Netflix](https://images.trvl-media.com/lodging/90000000/89510000/89502700/89502605/a4df93b3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Signature Cottage, 2 Bedrooms | Private kitchen | Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/90000000/89510000/89502700/89502605/w775h924x3y0-5b08ac43.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Signature Cottage, 2 Bedrooms | 2 bedrooms, individually decorated, individually furnished](https://images.trvl-media.com/lodging/90000000/89510000/89502700/89502605/9cd5859a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/90000000/89510000/89502700/89502605/b86441f4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Cottage in Clemson [](https://www.expedia.com/Clemson-Hotels-Clemson-Memorabilia-House.h89502605.Hotel-Information) 9.8/10 Exceptional (9 reviews) "We enjoyed our stay, it was the perfect size for our family of four. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Ashley $224 nightly $249 total Mar 24 - Mar 25 Total with taxes and fees [](https://www.expedia.com/Clemson-Hotels-Clemson-Memorabilia-House.h89502605.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/88000000/87340000/87337600/87337581/83fe6802.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/88000000/87340000/87337600/87337581/94af1b49.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/88000000/87340000/87337600/87337581/4c9b67dc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/88000000/87340000/87337600/87337581/7c7b67a2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Cottage in Cleveland [](https://www.expedia.com/Cleveland-Hotels-Gnome-Hill-Cottage.h87337581.Hotel-Information) 9.8/10 Exceptional (111 reviews) "We absolutely loved our stay! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Kayla R. $130 nightly $144 total Mar 22 - Mar 23 Total with taxes and fees [](https://www.expedia.com/Cleveland-Hotels-Gnome-Hill-Cottage.h87337581.Hotel-Information) ![Terrace/patio](https://images.trvl-media.com/lodging/39000000/38200000/38191100/38191009/w1015h757x6y0-8c36a621.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![3 bedrooms, free WiFi, bed sheets](https://images.trvl-media.com/lodging/39000000/38200000/38191100/38191009/7f9e5481.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Children's area](https://images.trvl-media.com/lodging/39000000/38200000/38191100/38191009/3c173cf3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/39000000/38200000/38191100/38191009/e3a10a02.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Cabin in Townville [](https://www.expedia.com/Townville-Hotels-Tiny-House-Min-From-Lake-Hartwellclemson.h38191009.Hotel-Information) 10/10 Exceptional (88 reviews) "Beautiful and clean cabin and wonderful scenery!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Michael F. $205 nightly $228 total Mar 21 - Mar 22 Total with taxes and fees [](https://www.expedia.com/Townville-Hotels-Tiny-House-Min-From-Lake-Hartwellclemson.h38191009.Hotel-Information) ![Interior](https://images.trvl-media.com/lodging/79000000/78400000/78399400/78399342/d683cef2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/79000000/78400000/78399400/78399342/84439ad2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![TV, fireplace](https://images.trvl-media.com/lodging/79000000/78400000/78399400/78399342/b2704678.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![TV, fireplace](https://images.trvl-media.com/lodging/79000000/78400000/78399400/78399342/060ec7cd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Apartment in Walhalla [](https://www.expedia.com/Walhalla-Hotels-Residences-On-Main-Issqueena-Suite.h78399342.Hotel-Information) 10/10 Exceptional (18 reviews) "Beautiful apartment- close to restaurants- very walkable to shopping.. must stay!!!! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Betty $267 nightly $281 total Mar 21 - Mar 22 Total with taxes and fees [](https://www.expedia.com/Walhalla-Hotels-Residences-On-Main-Issqueena-Suite.h78399342.Hotel-Information) ![Terrace/patio](https://images.trvl-media.com/lodging/114000000/113580000/113579000/113578929/47855e4c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, desk, iron/ironing board, travel crib](https://images.trvl-media.com/lodging/114000000/113580000/113579000/113578929/3c05f3f3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/114000000/113580000/113579000/113578929/f1eb10dd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV, fireplace, books](https://images.trvl-media.com/lodging/114000000/113580000/113579000/113578929/b27517c6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Cabin in Mountain Rest [](https://www.expedia.com/Mountain-Rest-Hotels-Blue-Laurel-Is-Nestled-In-The-Peaceful-Little-Town-Of-Mountain-Rest.h113578929.Hotel-Information) 10/10 Exceptional (34 reviews) "Great cabin in a great location." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Patricia K. $227 nightly $250 total Mar 25 - Mar 26 Total with taxes and fees [](https://www.expedia.com/Mountain-Rest-Hotels-Blue-Laurel-Is-Nestled-In-The-Peaceful-Little-Town-Of-Mountain-Rest.h113578929.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.com/Hotel-Search?startDate=2026-04-03&endDate=2026-04-04®ionId=553248635975748552&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&openPlayBack=true) ## Find vacation rentals that suit your style Cabins [](https://www.expedia.com/Hotel-Search?destination=Upstate+South+Carolina%2C+South+Carolina%2C+United+States+of+America®ionId=553248635975748552&latLong=34.711583%2C-82.278231&adults=2&startDate=2026-06-18&d1=2026-06-18&endDate=2026-06-21&d2=2026-06-21&lodging=CABIN) Cottages [](https://www.expedia.com/Hotel-Search?destination=Upstate+South+Carolina%2C+South+Carolina%2C+United+States+of+America®ionId=553248635975748552&latLong=34.711583%2C-82.278231&adults=2&startDate=2026-06-18&d1=2026-06-18&endDate=2026-06-21&d2=2026-06-21&lodging=COTTAGE) Private vacation homes [](https://www.expedia.com/Hotel-Search?destination=Upstate+South+Carolina%2C+South+Carolina%2C+United+States+of+America®ionId=553248635975748552&latLong=34.711583%2C-82.278231&adults=2&startDate=2026-06-18&d1=2026-06-18&endDate=2026-06-21&d2=2026-06-21&lodging=VACATION_HOME) Condos [](https://www.expedia.com/Hotel-Search?destination=Upstate+South+Carolina%2C+South+Carolina%2C+United+States+of+America®ionId=553248635975748552&latLong=34.711583%2C-82.278231&adults=2&startDate=2026-06-18&d1=2026-06-18&endDate=2026-06-21&d2=2026-06-21&lodging=CONDO) Houseboats [](https://www.expedia.com/Hotel-Search?destination=Upstate+South+Carolina%2C+South+Carolina%2C+United+States+of+America®ionId=553248635975748552&latLong=34.711583%2C-82.278231&adults=2&startDate=2026-06-18&d1=2026-06-18&endDate=2026-06-21&d2=2026-06-21&lodging=HOUSE_BOAT) Villas [](https://www.expedia.com/Hotel-Search?destination=Upstate+South+Carolina%2C+South+Carolina%2C+United+States+of+America®ionId=553248635975748552&latLong=34.711583%2C-82.278231&adults=2&startDate=2026-06-18&d1=2026-06-18&endDate=2026-06-21&d2=2026-06-21&lodging=VILLA) Aparthotels [](https://www.expedia.com/Hotel-Search?destination=Upstate+South+Carolina%2C+South+Carolina%2C+United+States+of+America®ionId=553248635975748552&latLong=34.711583%2C-82.278231&adults=2&startDate=2026-06-18&d1=2026-06-18&endDate=2026-06-21&d2=2026-06-21&lodging=APART_HOTEL) Apartments [](https://www.expedia.com/Hotel-Search?destination=Upstate+South+Carolina%2C+South+Carolina%2C+United+States+of+America®ionId=553248635975748552&latLong=34.711583%2C-82.278231&adults=2&startDate=2026-06-18&d1=2026-06-18&endDate=2026-06-21&d2=2026-06-21&lodging=APARTMENT) Chalets [](https://www.expedia.com/Hotel-Search?destination=Upstate+South+Carolina%2C+South+Carolina%2C+United+States+of+America®ionId=553248635975748552&latLong=34.711583%2C-82.278231&adults=2&startDate=2026-06-18&d1=2026-06-18&endDate=2026-06-21&d2=2026-06-21&lodging=CHALET) Residences [](https://www.expedia.com/Hotel-Search?destination=Upstate+South+Carolina%2C+South+Carolina%2C+United+States+of+America®ionId=553248635975748552&latLong=34.711583%2C-82.278231&adults=2&startDate=2026-06-18&d1=2026-06-18&endDate=2026-06-21&d2=2026-06-21&lodging=RESIDENCE) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.com/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FUpstate-South-Carolina-Vacation-Rentals.d553248635975748552.Travel-Guide-VacationRentals)[ Sign up, it's free ](https://expedia.com/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FUpstate-South-Carolina-Vacation-Rentals.d553248635975748552.Travel-Guide-VacationRentals) ## Top Upstate South Carolina Hotel Reviews ![Hyatt Place Greenville/Haywood](https://images.trvl-media.com/lodging/1000000/70000/64600/64570/w3840h2556x0y3-09ad394d_y.jpg) ### Hyatt Place Greenville/Haywood 10/10 Excellent "Great place to stay " [](https://expedia.com/Greenville-Hotels-Hyatt-Place-GreenvilleHaywood.h64570.Hotel-Information) ![Mint House Greenville Downtown by Kasa](https://images.trvl-media.com/lodging/39000000/38600000/38593300/38593248/5e1376bb_y.jpg) ### Mint House Greenville Downtown by Kasa 10/10 Excellent "It was a very nice room for me and my wife every thing was clean just wish they had a tv in the bedroom " [](https://expedia.com/Greenville-Spartanburg-Hotels-Mint-House-Downtown-Greenville.h38593248.Hotel-Information) ![Hotel Hartness](https://images.trvl-media.com/lodging/90000000/89690000/89689300/89689223/91df3d0d_y.jpg) ### Hotel Hartness 10/10 Excellent "Everything about this location is fantastic. It’s a beautiful beautiful place in very unique to any hotel way better." [](https://expedia.com/Greenville-Hotels-Hotel-Hartness.h89689223.Hotel-Information) ![Best Western Plus Greenville I-385 Inn & Suites](https://images.trvl-media.com/lodging/1000000/30000/23100/23003/f09ffe86_y.jpg) ### Best Western Plus Greenville I-385 Inn & Suites 10/10 Excellent "Breakfast was buffet, hot, and plentiful. One of those cool coffee machines with all the flavors as well! Good stay and very close to I-385, restaurants, and shopping;10 minutes to downtown." [](https://expedia.com/Greenville-Hotels-Best-Western-Plus-Greenville-I-385-Inn-Suites.h23003.Hotel-Information) ![La Quinta Inn & Suites by Wyndham Greenville Woodruff Rd.](https://images.trvl-media.com/lodging/23000000/22520000/22513500/22513453/5971f25f_y.jpg) ### La Quinta Inn & Suites by Wyndham Greenville Woodruff Rd. 10/10 Excellent "Room was showing age, but was clean . Bed was a little hard. Staff was friendly and efficient. The breakfast guy was nice but a little distracted because of multitasking. Can’t beat the location or beautiful balcony views." [](https://expedia.com/Greenville-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Greenville-Woodruff-Rd.h22513453.Hotel-Information) ![Embassy Suites Greenville Golf Resort & Conference Center](https://images.trvl-media.com/lodging/1000000/10000/3300/3223/b0e15e12_y.jpg) ### Embassy Suites Greenville Golf Resort & Conference Center 10/10 Excellent "ALL Was Well!" [](https://expedia.com/Greenville-Hotels-Embassy-Suites-Greenville-Golf-Resort-Conference-Center.h3223.Hotel-Information) ![Drury Inn & Suites Greenville](https://images.trvl-media.com/lodging/2000000/1540000/1533500/1533439/6d7853ae_y.jpg) ### Drury Inn & Suites Greenville 10/10 Excellent "Clean hotel, friendly knowledgeable staff" [](https://expedia.com/Greenville-Hotels-Drury-Inn-Suites-Greenville.h1533439.Hotel-Information) ![Aloft Greenville Downtown](https://images.trvl-media.com/lodging/12000000/11960000/11959000/11958914/d91c1d51_y.jpg) ### Aloft Greenville Downtown 10/10 Excellent "Great stay at Aloft Greenville Downtown! Super clean, modern rooms and an amazing location right in the heart of downtown. The staff was very friendly and helpful. I’d definitely stay here again!" [](https://expedia.com/Greenville-Hotels-Aloft-Greenville-Downtown.h11958914.Hotel-Information) ![Homewood Suites by Hilton Greenville Downtown](https://images.trvl-media.com/lodging/30000000/29060000/29050100/29050020/88b33cc2_y.jpg) ### Homewood Suites by Hilton Greenville Downtown 10/10 Excellent "Super friendly staff and well located hotel. Rooms were light and spacious. " [](https://expedia.com/Greenville-Hotels-Homewood-Suites-By-Hilton-Greenville-Downtown.h29050020.Hotel-Information) ## Find out more about Upstate South Carolina **Everything you need to know about Upstate South Carolina vacation rentals** Whether you’re excited for the perfect family vacation, a romantic getaway for two, or the ultimate city break, we’ve got the Upstate South Carolina vacation rental for you. At Expedia, you can take your pick from private vacation homes, apartments, condos, resorts, cabins, villas, motels. The list goes on, and on …and on. There’s just as wide a choice of amenities, too. Maybe you’re dreaming of your own pool, long evenings in a hot tub, or watching the kids laugh through the day at a waterpark. Maybe you just want a quiet retreat in a pet-friendly apartment. Well, we can help you find it. Hunt out the perfect Upstate South Carolina vacation rental for you by simply entering your desired dates. Then check your favorite filters to narrow down your search. **Upstate South Carolina vacation rentals: An excellent choice for every season** Whenever you want to travel, a warm welcome awaits you in Upstate South Carolina. If you’re looking for a little peace, consider booking during the quieter low season months. For more hustle and bustle, you may prefer to visit Upstate South Carolina in high season. Prices vary throughout the year. Your chosen location, property type, and amenities will impact the cost of your trip, too. The selection of properties we have chosen for you start as low as $116 per night. Rates vary depending on your travel dates, location, and amenities so make a search and you might find even better deals! **How to find incredible deals on Upstate South Carolina rentals** At Expedia, we put the best Upstate South Carolina vacation rentals in one place. All you need to do is take your pick. And as we offer book now, pay later options, as well as free cancellation on some properties, you can plan your trip with total peace of mind. You’ll always find a great deal with Expedia. To find some top Upstate South Carolina rental deals, enter your travel dates, and sort your search results by price. You can also filter by budget, so you only see accommodation in your ballpark. Next, add any filters you want—and just like that, you’ve built your dream Upstate South Carolina vacation. If you’re looking for a little inspiration, browse our latest incredible offers, or use the map to view all accommodation in and around Upstate South Carolina. And to unlock even more fantastic deals, bundle your accommodation, flights, and car rental together to save and book with Expedia in complete confidence. ## Explore a world of travel with Expedia - Trending destinations on Expedia.com - All accommodation types in Upstate South Carolina ### Trending destinations on Expedia.com - [Destin Vacation Rentals ](https://www.expedia.com/Destin-Vacation-Rentals.d6906.Travel-Guide-VacationRentals) - [Panama City Vacation Rentals ](https://www.expedia.com/Panama-City-Beach-Vacation-Rentals.d8021.Travel-Guide-VacationRentals) - [Hilton Head Vacation Rentals ](https://www.expedia.com/Hilton-Head-Island-Vacation-Rentals.d601684.Travel-Guide-VacationRentals) - [Gulf Shores Vacation Rentals ](https://www.expedia.com/Gulf-Shores-Vacation-Rentals.d603078.Travel-Guide-VacationRentals) - [Key West Vacation Rentals ](https://www.expedia.com/Key-West-Vacation-Rentals.d1187.Travel-Guide-VacationRentals) - [Gatlinburg Vacation Rentals ](https://www.expedia.com/Gatlinburg-Vacation-Rentals.d7474.Travel-Guide-VacationRentals) - 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