Title: Upstate South Carolina Vacation Rentals from $120: Search Short-Term Rentals | Expedia.com [Upstate South Carolina Travel Guide](https://expedia.com/Upstate-South-Carolina.dx553248635975748552)[Hotels in Upstate South Carolina](https://expedia.com/Upstate-South-Carolina-Hotels.d553248635975748552.Travel-Guide-Hotels)[Flights to Upstate South Carolina](https://expedia.com/Cheap-Flights-To-Upstate-South-Carolina.d553248635975748552.Travel-Guide-Flights)[Things to do in Upstate South Carolina](https://expedia.com/Things-To-Do-In-Upstate-South-Carolina.d553248635975748552.Travel-Guide-Activities)[Car Rentals in Upstate South Carolina](https://expedia.com/Car-Rentals-In-Upstate-South-Carolina.d553248635975748552.Car-Rental-Guide)[Upstate South Carolina Vacation Packages](https://expedia.com/Upstate-South-Carolina.d553248635975748552.Destination-Travel-Guides) ![It is only a 1 mile hike to this beauty. View a video about it here: https://www.hdcarolina.com/episode/riley-moore-falls #Waterfall](https://images.trvl-media.com/place/6122927/69b8ebaa-53a3-428e-ba53-37ac2de11862.jpg?impolicy=fcrop&w=1200&h=500&q=medium) Photo by Ryan Watts ![](https://images.trvl-media.com/place/6122927/69b8ebaa-53a3-428e-ba53-37ac2de11862.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light_bundle_and_save.svg) ### Bundle & Save Get more, spend less whenever you see Bundle & Save deals - ![](https://a.travel-assets.com/travel-assets-manager/pictograms-expedia/light__onekey.svg) ### OneKeyCash Earn OneKeyCash on all your eligible bookings - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light_ftc.svg) ### Upfront pricing We are not like the others - we include taxes and fees ## Check prices for these dates In two weeks [Mar 20 - Mar 22](https://www.expedia.com/Hotel-Search?regionId=553248635975748552&startDate=2026-03-20&endDate=2026-03-22&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two months [May 1 - May 3](https://www.expedia.com/Hotel-Search?regionId=553248635975748552&startDate=2026-05-01&endDate=2026-05-03&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In three months [May 29 - May 31](https://www.expedia.com/Hotel-Search?regionId=553248635975748552&startDate=2026-05-29&endDate=2026-05-31&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In four months [Jun 26 - Jun 28](https://www.expedia.com/Hotel-Search?regionId=553248635975748552&startDate=2026-06-26&endDate=2026-06-28&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Our top choices for Upstate South Carolina vacation rentals ![Premium bedding, in-room safe, individually furnished, laptop workspace](https://images.trvl-media.com/lodging/123000000/122100000/122099800/122099740/afe0f510.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Seasonal outdoor pool, open 7:00 AM to 10:00 PM, pool umbrellas](https://images.trvl-media.com/lodging/123000000/122100000/122099800/122099740/b26b87ac.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Cabin, 1 Bedroom, Courtyard View | Front of property](https://images.trvl-media.com/lodging/123000000/122100000/122099800/122099740/f825207a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, in-room safe, individually furnished, laptop workspace](https://images.trvl-media.com/lodging/123000000/122100000/122099800/122099740/4d5d913d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Cabin in Pickens [](https://www.expedia.com/Pickens-Hotels-Carolina-Camp-Cedar.h122099740.Hotel-Information) 10/10 Exceptional (2 reviews) "The cottage was clean, staff was so friendly, our stay was quiet and peaceful… it was perfect! Definitely planning to stay there again!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Katlynn $170 nightly $189 total Mar 15 - Mar 16 Total with taxes and fees [](https://www.expedia.com/Pickens-Hotels-Carolina-Camp-Cedar.h122099740.Hotel-Information) ![View from property](https://images.trvl-media.com/lodging/111000000/110490000/110487400/110487306/d7c06df6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/111000000/110490000/110487400/110487306/53271cae.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Shower, towels, soap, shampoo](https://images.trvl-media.com/lodging/111000000/110490000/110487400/110487306/2da98b27.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, desk, laptop workspace, bed sheets](https://images.trvl-media.com/lodging/111000000/110490000/110487400/110487306/f29b16c6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Cabin in Seneca [](https://www.expedia.com/Postcard-Cabins-Lake-Hartwell.h110487306.Hotel-Information) 9.8/10 Exceptional (64 reviews) "Excellent stay." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Beonca $109 nightly $120 total Mar 9 - Mar 10 Total with taxes and fees [](https://www.expedia.com/Postcard-Cabins-Lake-Hartwell.h110487306.Hotel-Information) ![Trailside Wedge Cottage | Terrace/patio](https://images.trvl-media.com/lodging/89000000/88370000/88362000/88361952/346fcb37.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/89000000/88370000/88362000/88361952/87440d66.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Trailside Wedge Cottage | Terrace/patio](https://images.trvl-media.com/lodging/89000000/88370000/88362000/88361952/fa38c3ad.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Trailside Wedge Cottage | Living area | Smart TV](https://images.trvl-media.com/lodging/89000000/88370000/88362000/88361952/f19cdb36.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Aparthotel in Travelers Rest [](https://www.expedia.com/Travelers-Rest-Hotels-The-Station-By-Compo-Hotels.h88361952.Hotel-Information) 10/10 Exceptional (17 reviews) "great place perfect for more privacy vs. a standard hotel" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) John $289 nightly $318 total Mar 9 - Mar 10 Total with taxes and fees [](https://www.expedia.com/Travelers-Rest-Hotels-The-Station-By-Compo-Hotels.h88361952.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/96000000/95310000/95305700/95305698/51159ba6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV, DVD player](https://images.trvl-media.com/lodging/96000000/95310000/95305700/95305698/02ce48d2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/96000000/95310000/95305700/95305698/a4ea3c70.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/96000000/95310000/95305700/95305698/e35ebf2a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Apartment in Landrum [](https://www.expedia.com/Landrum-Hotels-Private-Apartment-On-Beautiful-Grounds.h95305698.Hotel-Information) 9.8/10 Exceptional (35 reviews) "We loved our stay here! Friendly hosts, clean space, great location and their cute kitty Luna even stopped by one evening for a visit which I loved! Highly recommend staying here " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Cassidy W. $148 nightly $164 total Mar 6 - Mar 7 Total with taxes and fees [](https://www.expedia.com/Landrum-Hotels-Private-Apartment-On-Beautiful-Grounds.h95305698.Hotel-Information) ![Property grounds](https://images.trvl-media.com/lodging/67000000/66030000/66026900/66026894/efec02d1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/67000000/66030000/66026900/66026894/fc94d8c0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV, table tennis](https://images.trvl-media.com/lodging/67000000/66030000/66026900/66026894/ad2b1b86.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV, table tennis](https://images.trvl-media.com/lodging/67000000/66030000/66026900/66026894/1a5c9883.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Cabin in Pickens [](https://www.expedia.com/Pickens-Hotels-Luxury-Vacation-Mtn-Home.h66026894.Hotel-Information) 9.8/10 Exceptional (25 reviews) "Everything was perfect from the hot tub to the comfort of the beds!!!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Kelly C. $297 nightly $329 total Mar 6 - Mar 7 Total with taxes and fees [](https://www.expedia.com/Pickens-Hotels-Luxury-Vacation-Mtn-Home.h66026894.Hotel-Information) ![Sauna](https://images.trvl-media.com/lodging/115000000/114810000/114805200/114805191/w1284h1856x0y1-5421e5b7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, in-room safe, WiFi, bed sheets](https://images.trvl-media.com/lodging/115000000/114810000/114805200/114805191/8c57b2cf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/115000000/114810000/114805200/114805191/02b206f0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/115000000/114810000/114805200/114805191/611c0f59.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Cabin in Travelers Rest [](https://www.expedia.com/Travelers-Rest-Hotels-Unit-9-Beautiful-Bell-Tent-With-AC-And-WiFi-In-Travelers-Rest.h114805191.Hotel-Information) 10/10 Exceptional (3 reviews) "Hot tub, sauna and cold plunge are really nice. Bathrooms are clean and nice. I was able to work remotely in their clubhouse with fast internet. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Dustin W. $182 nightly $200 total Mar 6 - Mar 7 Total with taxes and fees [](https://www.expedia.com/Travelers-Rest-Hotels-Unit-9-Beautiful-Bell-Tent-With-AC-And-WiFi-In-Travelers-Rest.h114805191.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/111000000/110820000/110812100/110812036/f95c7c86.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/111000000/110820000/110812100/110812036/2eb8978f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/111000000/110820000/110812100/110812036/5ca265fe.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/111000000/110820000/110812100/110812036/3a781422.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Cottage in Townville [](https://www.expedia.com/Townville-Hotels-Broyles-Landing-Cottage-At-Lake-Hartwell-SC.h110812036.Hotel-Information) 10/10 Exceptional (19 reviews) "Clean, easy to find, plenty of parking" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Anonymous traveler $205 nightly $228 total Mar 6 - Mar 7 Total with taxes and fees [](https://www.expedia.com/Townville-Hotels-Broyles-Landing-Cottage-At-Lake-Hartwell-SC.h110812036.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/106000000/105420000/105414500/105414462/f87a02a7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![3 bedrooms, WiFi, bed sheets](https://images.trvl-media.com/lodging/106000000/105420000/105414500/105414462/293f8327.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV](https://images.trvl-media.com/lodging/106000000/105420000/105414500/105414462/8d5b0729.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, coffee/tea maker, blender](https://images.trvl-media.com/lodging/106000000/105420000/105414500/105414462/031cfc6e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Cabin in Townville [](https://www.expedia.com/Townville-Hotels-Brand-NewCozy-CabinLake-HartwellGreen-Pond-LndgBroyles-LandingBoat-Shelter.h105414462.Hotel-Information) 10/10 Exceptional (9 reviews) "Great Place to stay for a fishing trip." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Kindal D. $237 nightly $263 total Mar 6 - Mar 7 Total with taxes and fees [](https://www.expedia.com/Townville-Hotels-Brand-NewCozy-CabinLake-HartwellGreen-Pond-LndgBroyles-LandingBoat-Shelter.h105414462.Hotel-Information) ![1 bedroom, free WiFi, bed sheets](https://images.trvl-media.com/lodging/81000000/80940000/80930400/80930381/9a8d8ddd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV](https://images.trvl-media.com/lodging/81000000/80940000/80930400/80930381/53855e39.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV](https://images.trvl-media.com/lodging/81000000/80940000/80930400/80930381/8bccb626.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Dining](https://images.trvl-media.com/lodging/81000000/80940000/80930400/80930381/a6933580.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Cabin in Cleveland [](https://www.expedia.com/Cleveland-Hotels-Modern-Cabin-Near-Table-RockPretty-Place.h80930381.Hotel-Information) 10/10 Exceptional (70 reviews) "We had all we needed in the kitchen and enjoyed our meals in the sunroom. The cabin was perfect! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jay P. $200 nightly $220 total Mar 8 - Mar 9 Total with taxes and fees [](https://www.expedia.com/Cleveland-Hotels-Modern-Cabin-Near-Table-RockPretty-Place.h80930381.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/108000000/107780000/107773400/107773310/7a59f7da.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/108000000/107780000/107773400/107773310/dae7e187.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, bed sheets](https://images.trvl-media.com/lodging/108000000/107780000/107773400/107773310/2d362c1b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/108000000/107780000/107773400/107773310/c6cccc88.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Cottage in Pickens [](https://www.expedia.com/Pickens-Hotels-Romantic-Cottage-Getaway.h107773310.Hotel-Information) 10/10 Exceptional (16 reviews) "Amazing secluded retreat!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Stephen N. $183 nightly $203 total Mar 8 - Mar 9 Total with taxes and fees [](https://www.expedia.com/Pickens-Hotels-Romantic-Cottage-Getaway.h107773310.Hotel-Information) ![Outdoor dining](https://images.trvl-media.com/lodging/108000000/107170000/107165600/107165576/561f96a3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/108000000/107170000/107165600/107165576/eb6bc512.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/108000000/107170000/107165600/107165576/0f0a6ac9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/108000000/107170000/107165600/107165576/w2030h1365x0y0-c29ec3e5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Cottage in Walhalla [](https://www.expedia.com/Walhalla-Hotels-Rainyville-Emerald-Charming-Cottage-With-Loft-In-Walhalla.h107165576.Hotel-Information) 10/10 Exceptional (11 reviews) "Perfect home away from home. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Christine $260 nightly $286 total Mar 8 - Mar 9 Total with taxes and fees [](https://www.expedia.com/Walhalla-Hotels-Rainyville-Emerald-Charming-Cottage-With-Loft-In-Walhalla.h107165576.Hotel-Information) ![Terrace/patio](https://images.trvl-media.com/lodging/107000000/106270000/106262900/106262845/38d59f5d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV, DVD player, books, music library](https://images.trvl-media.com/lodging/107000000/106270000/106262900/106262845/13049da2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/107000000/106270000/106262900/106262845/1483dace.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior detail](https://images.trvl-media.com/lodging/107000000/106270000/106262900/106262845/f7117701.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Cabin in Enoree [](https://www.expedia.com/Enoree-Hotels-Cozy-Cabin-In-The-Woods-Pets-Welcome.h106262845.Hotel-Information) 10/10 Exceptional (8 reviews) "Cabin was perfect for our stay-cozy and quiet. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jan F. $175 nightly $194 total Mar 25 - Mar 26 Total with taxes and fees [](https://www.expedia.com/Enoree-Hotels-Cozy-Cabin-In-The-Woods-Pets-Welcome.h106262845.Hotel-Information) ![Signature Cottage, 2 Bedrooms | Living room | 43-inch Smart TV with cable channels, TV, Netflix](https://images.trvl-media.com/lodging/90000000/89510000/89502700/89502605/a4df93b3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/90000000/89510000/89502700/89502605/b86441f4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Signature Cottage, 2 Bedrooms | Private kitchen | Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/90000000/89510000/89502700/89502605/0d77f138.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Signature Cottage, 2 Bedrooms | Private kitchen | Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/90000000/89510000/89502700/89502605/w775h924x3y0-5b08ac43.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Cottage in Clemson [](https://www.expedia.com/Clemson-Hotels-Clemson-Memorabilia-House.h89502605.Hotel-Information) 9.8/10 Exceptional (9 reviews) "We enjoyed our stay, it was the perfect size for our family of four. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Ashley $214 nightly $238 total Mar 8 - Mar 9 Total with taxes and fees [](https://www.expedia.com/Clemson-Hotels-Clemson-Memorabilia-House.h89502605.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/118000000/117970000/117968000/117967992/6856c3ec.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV, fireplace](https://images.trvl-media.com/lodging/118000000/117970000/117968000/117967992/5fe9e2fe.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/118000000/117970000/117968000/117967992/30352fd0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/118000000/117970000/117968000/117967992/c148f208.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Cabin in Greenville [](https://www.expedia.com/Greenville-Hotels-Historic-19th-Century-Cabin-In-Greenville.h117967992.Hotel-Information) 9.8/10 Exceptional (7 reviews) "Great cabin in the perfect location. Hosts have thought of everything. Will definitely stay here again! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) David R. $151 nightly $166 total Mar 11 - Mar 12 Total with taxes and fees [](https://www.expedia.com/Greenville-Hotels-Historic-19th-Century-Cabin-In-Greenville.h117967992.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/88000000/87340000/87337600/87337581/83fe6802.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, free WiFi, bed sheets](https://images.trvl-media.com/lodging/88000000/87340000/87337600/87337581/f5e918bc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/88000000/87340000/87337600/87337581/7c7b67a2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/88000000/87340000/87337600/87337581/94af1b49.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Cottage in Cleveland [](https://www.expedia.com/Cleveland-Hotels-Gnome-Hill-Cottage.h87337581.Hotel-Information) 9.8/10 Exceptional (110 reviews) "We absolutely loved our stay! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Kayla R. $130 nightly $144 total Mar 8 - Mar 9 Total with taxes and fees [](https://www.expedia.com/Cleveland-Hotels-Gnome-Hill-Cottage.h87337581.Hotel-Information) ![Outdoor spa tub](https://images.trvl-media.com/lodging/77000000/76930000/76929000/76928997/de87b393.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/77000000/76930000/76929000/76928997/5e6e3f5b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV](https://images.trvl-media.com/lodging/77000000/76930000/76929000/76928997/1a9df087.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, free WiFi, bed sheets](https://images.trvl-media.com/lodging/77000000/76930000/76929000/76928997/394f1525.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Cabin in Pickens [](https://www.expedia.com/Pickens-Hotels-Lazy-Bear-Retreat-By-The-Creek.h76928997.Hotel-Information) 10/10 Exceptional (49 reviews) "What a beautiful little getaway! Great communication with owner, easy to find the location and entry. Everything was very clean and working as it should. Loved the hot tub." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Molly $166 nightly $184 total Mar 8 - Mar 9 Total with taxes and fees [](https://www.expedia.com/Pickens-Hotels-Lazy-Bear-Retreat-By-The-Creek.h76928997.Hotel-Information) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/79000000/78140000/78137300/78137271/ff8281c0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/79000000/78140000/78137300/78137271/370e1a1e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 bedrooms, desk, iron/ironing board, travel crib](https://images.trvl-media.com/lodging/79000000/78140000/78137300/78137271/ec7d22d4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/79000000/78140000/78137300/78137271/245dc985.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Vacation Home in Woodside Cotton Mill Village Historic District [](https://www.expedia.com/Greenville-Hotels-The-Blue-Bungalow-By-Unity-Park-Newly-Renovated.h78137271.Hotel-Information) 9.8/10 Exceptional (88 reviews) "The house was super clean and nice! The host was awesome. We thoroughly enjoyed our stay. Convenient to everything. We will definitely stay again!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Lisa $200 nightly $220 total Mar 11 - Mar 12 Total with taxes and fees [](https://www.expedia.com/Greenville-Hotels-The-Blue-Bungalow-By-Unity-Park-Newly-Renovated.h78137271.Hotel-Information) ![3 bedrooms, free WiFi, bed sheets](https://images.trvl-media.com/lodging/92000000/91710000/91706100/91706084/cf633eeb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/92000000/91710000/91706100/91706084/18f029af.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, coffee/tea maker, blender](https://images.trvl-media.com/lodging/92000000/91710000/91706100/91706084/1021d7d6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/92000000/91710000/91706100/91706084/986eaefd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Cabin in Townville [](https://www.expedia.com/Townville-Hotels-Brand-New-14-Mile-To-Lake-HartwellBroyles-Landing-Mins-To-Clemson.h91706084.Hotel-Information) 10/10 Exceptional (16 reviews) "Definitely a great stay after visiting multiple lakes and trails. Planning to visit again." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Patrick S. $237 nightly $263 total Mar 6 - Mar 7 Total with taxes and fees [](https://www.expedia.com/Townville-Hotels-Brand-New-14-Mile-To-Lake-HartwellBroyles-Landing-Mins-To-Clemson.h91706084.Hotel-Information) ![Smart TV, fireplace, DVD player, books](https://images.trvl-media.com/lodging/116000000/115160000/115150900/115150808/07379db5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/116000000/115160000/115150900/115150808/268d57b4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV, fireplace, DVD player, books](https://images.trvl-media.com/lodging/116000000/115160000/115150900/115150808/cdb11631.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/116000000/115160000/115150900/115150808/a96d5720.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Apartment in Townville [](https://www.expedia.com/Townville-Hotels-Enchanting-1-Bedroom-Cabin-In-Townville.h115150808.Hotel-Information) 9.4/10 Exceptional (15 reviews) "Great place, great hosts, will definitely be back for another weekend getaway on the lake. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Brian M. $149 nightly $165 total Mar 6 - Mar 7 Total with taxes and fees [](https://www.expedia.com/Townville-Hotels-Enchanting-1-Bedroom-Cabin-In-Townville.h115150808.Hotel-Information) ![Terrace/patio](https://images.trvl-media.com/lodging/39000000/38200000/38191100/38191009/w1015h757x6y0-8c36a621.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![3 bedrooms, free WiFi, bed sheets](https://images.trvl-media.com/lodging/39000000/38200000/38191100/38191009/7f9e5481.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, coffee/tea maker, blender](https://images.trvl-media.com/lodging/39000000/38200000/38191100/38191009/b5050b0b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/39000000/38200000/38191100/38191009/e3a10a02.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Cabin in Townville [](https://www.expedia.com/Townville-Hotels-Tiny-House-Min-From-Lake-Hartwellclemson.h38191009.Hotel-Information) 10/10 Exceptional (88 reviews) "Beautiful and clean cabin and wonderful scenery!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Michael F. $205 nightly $228 total Mar 6 - Mar 7 Total with taxes and fees [](https://www.expedia.com/Townville-Hotels-Tiny-House-Min-From-Lake-Hartwellclemson.h38191009.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.com/Hotel-Search?startDate=2026-03-19&endDate=2026-03-20®ionId=553248635975748552&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&openPlayBack=true) ![](https://forever.travel-assets.com/flex/flexmanager/images/2026/02/06/expedia-sale-2026-desktop-us-ca.jpg?impolicy=fcrop&w=1400&h=600&q=mediumHigh) ## The Annual Vacation Sale Members save up to 40% on hotels and homes. Plan this year’s big trip and save. [Book now](https://expedia.com/deals?rfrr=VR_SPRING_PROMO_553248635975748552) ## Find vacation rentals that suit your style Cabins [](https://www.expedia.com/Hotel-Search?destination=Upstate+South+Carolina%2C+South+Carolina%2C+United+States+of+America®ionId=553248635975748552&latLong=34.711583%2C-82.278231&adults=2&startDate=2026-06-03&d1=2026-06-03&endDate=2026-06-06&d2=2026-06-06&lodging=CABIN) Cottages [](https://www.expedia.com/Hotel-Search?destination=Upstate+South+Carolina%2C+South+Carolina%2C+United+States+of+America®ionId=553248635975748552&latLong=34.711583%2C-82.278231&adults=2&startDate=2026-06-03&d1=2026-06-03&endDate=2026-06-06&d2=2026-06-06&lodging=COTTAGE) Private vacation homes [](https://www.expedia.com/Hotel-Search?destination=Upstate+South+Carolina%2C+South+Carolina%2C+United+States+of+America®ionId=553248635975748552&latLong=34.711583%2C-82.278231&adults=2&startDate=2026-06-03&d1=2026-06-03&endDate=2026-06-06&d2=2026-06-06&lodging=VACATION_HOME) Condos [](https://www.expedia.com/Hotel-Search?destination=Upstate+South+Carolina%2C+South+Carolina%2C+United+States+of+America®ionId=553248635975748552&latLong=34.711583%2C-82.278231&adults=2&startDate=2026-06-03&d1=2026-06-03&endDate=2026-06-06&d2=2026-06-06&lodging=CONDO) Houseboats [](https://www.expedia.com/Hotel-Search?destination=Upstate+South+Carolina%2C+South+Carolina%2C+United+States+of+America®ionId=553248635975748552&latLong=34.711583%2C-82.278231&adults=2&startDate=2026-06-03&d1=2026-06-03&endDate=2026-06-06&d2=2026-06-06&lodging=HOUSE_BOAT) Aparthotels [](https://www.expedia.com/Hotel-Search?destination=Upstate+South+Carolina%2C+South+Carolina%2C+United+States+of+America®ionId=553248635975748552&latLong=34.711583%2C-82.278231&adults=2&startDate=2026-06-03&d1=2026-06-03&endDate=2026-06-06&d2=2026-06-06&lodging=APART_HOTEL) Villas [](https://www.expedia.com/Hotel-Search?destination=Upstate+South+Carolina%2C+South+Carolina%2C+United+States+of+America®ionId=553248635975748552&latLong=34.711583%2C-82.278231&adults=2&startDate=2026-06-03&d1=2026-06-03&endDate=2026-06-06&d2=2026-06-06&lodging=VILLA) Apartments [](https://www.expedia.com/Hotel-Search?destination=Upstate+South+Carolina%2C+South+Carolina%2C+United+States+of+America®ionId=553248635975748552&latLong=34.711583%2C-82.278231&adults=2&startDate=2026-06-03&d1=2026-06-03&endDate=2026-06-06&d2=2026-06-06&lodging=APARTMENT) Chalets [](https://www.expedia.com/Hotel-Search?destination=Upstate+South+Carolina%2C+South+Carolina%2C+United+States+of+America®ionId=553248635975748552&latLong=34.711583%2C-82.278231&adults=2&startDate=2026-06-03&d1=2026-06-03&endDate=2026-06-06&d2=2026-06-06&lodging=CHALET) Residences [](https://www.expedia.com/Hotel-Search?destination=Upstate+South+Carolina%2C+South+Carolina%2C+United+States+of+America®ionId=553248635975748552&latLong=34.711583%2C-82.278231&adults=2&startDate=2026-06-03&d1=2026-06-03&endDate=2026-06-06&d2=2026-06-06&lodging=RESIDENCE) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.com/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FUpstate-South-Carolina-Vacation-Rentals.d553248635975748552.Travel-Guide-VacationRentals)[ Sign up, it's free ](https://expedia.com/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FUpstate-South-Carolina-Vacation-Rentals.d553248635975748552.Travel-Guide-VacationRentals) ## Top Upstate South Carolina Hotel Reviews ![Embassy Suites Greenville Golf Resort & Conference Center](https://images.trvl-media.com/lodging/1000000/10000/3300/3223/b0e15e12_y.jpg) ### Embassy Suites Greenville Golf Resort & Conference Center 10/10 Excellent "The staff at this hotel was super friendly and the room was great! We really enjoyed the breakfast and happy hour! Overall, I would highly recommend this hotel!" [](https://expedia.com/Greenville-Hotels-Embassy-Suites-Greenville-Golf-Resort-Conference-Center.h3223.Hotel-Information) ![Grand Bohemian Lodge Greenville, Autograph Collection](https://images.trvl-media.com/lodging/72000000/71770000/71762700/71762652/6f048029_y.jpg) ### Grand Bohemian Lodge Greenville, Autograph Collection 10/10 Excellent "Perfectly located to walk to the river, downtown and peace center. Gorgeous asthetic, and pristine rooms, we loved the restaurant also! Staff we courteous and helpful in everyway. 10/10" [](https://expedia.com/Greenville-Hotels-Grand-Bohemian-Lodge-Greenville.h71762652.Hotel-Information) ![Aloft Greenville Downtown](https://images.trvl-media.com/lodging/12000000/11960000/11959000/11958914/d91c1d51_y.jpg) ### Aloft Greenville Downtown 10/10 Excellent "Perfect location " [](https://expedia.com/Greenville-Hotels-Aloft-Greenville-Downtown.h11958914.Hotel-Information) ![Hyatt Place Greenville/Haywood](https://images.trvl-media.com/lodging/1000000/70000/64600/64570/w3840h2556x0y3-09ad394d_y.jpg) ### Hyatt Place Greenville/Haywood 10/10 Excellent "The room was clean, beds were comfortable and not stiff as a board, staff friendly, parking lots were well lit, restaurants, the mall, and other establishments close by. The breakfast was good, although not as much of a selection as we’d have preferred. Overall pleased with our experience and would stay again!" [](https://expedia.com/Greenville-Hotels-Hyatt-Place-GreenvilleHaywood.h64570.Hotel-Information) ![Hilton Greenville](https://images.trvl-media.com/lodging/1000000/30000/23200/23172/8017eeff_y.jpg) ### Hilton Greenville 10/10 Excellent "Friendly staff, clean rooms and comfortable bed" [](https://expedia.com/Greenville-Hotels-Hilton-Greenville.h23172.Hotel-Information) ![Best Western Plus Clemson Hotel & Conference Center](https://images.trvl-media.com/lodging/1000000/10000/1400/1370/w3837h2558x3y3-4efd29d6_y.jpg) ### Best Western Plus Clemson Hotel & Conference Center 10/10 Excellent "The room was very clean, it was a room with a king bed and a sofa bed plus a microwave, mini fridge, coffee machine. The reception desk was very helpful when I had to do a late check in." [](https://expedia.com/Anderson-Hotels-Best-Western-Plus-University-Inn-Conference-Center.h1370.Hotel-Information) ![Hyatt Place Greenville Downtown](https://images.trvl-media.com/lodging/28000000/27050000/27043000/27042919/027a8aef_y.jpg) ### Hyatt Place Greenville Downtown 10/10 Excellent "Great location, clean and polite staff " [](https://expedia.com/Greenville-Hotels-Hyatt-Place-GreenvilleDowntown.h27042919.Hotel-Information) ![Crowne Plaza Hotel Greenville-I-385-Roper Mtn Rd by IHG](https://images.trvl-media.com/lodging/1000000/10000/1400/1379/605b3e5f_y.jpg) ### Crowne Plaza Hotel Greenville-I-385-Roper Mtn Rd by IHG 10/10 Excellent "All the staff was extremely friendly " [](https://expedia.com/Greenville-Hotels-Crowne-Plaza-Hotel-Greenville-I-385-Roper-Mtn-Rd.h1379.Hotel-Information) ![Hotel Hartness](https://images.trvl-media.com/lodging/90000000/89690000/89689300/89689223/91df3d0d_y.jpg) ### Hotel Hartness 10/10 Excellent "The hotel had a wonderful smell when you walk in. They have very high-end lotions and hair products. Great lighting getting ready. Great lighting for reading. Overall the hotel was a 10 in my opinion." [](https://expedia.com/Greenville-Hotels-Hotel-Hartness.h89689223.Hotel-Information) ## Find out more about Upstate South Carolina **Everything you need to know about Upstate South Carolina vacation rentals** Whether you’re excited for the perfect family vacation, a romantic getaway for two, or the ultimate city break, we’ve got the Upstate South Carolina vacation rental for you. At Expedia, you can take your pick from private vacation homes, apartments, condos, resorts, cabins, villas, motels. The list goes on, and on …and on. There’s just as wide a choice of amenities, too. Maybe you’re dreaming of your own pool, long evenings in a hot tub, or watching the kids laugh through the day at a waterpark. Maybe you just want a quiet retreat in a pet-friendly apartment. Well, we can help you find it. Hunt out the perfect Upstate South Carolina vacation rental for you by simply entering your desired dates. Then check your favorite filters to narrow down your search. **Upstate South Carolina vacation rentals: An excellent choice for every season** Whenever you want to travel, a warm welcome awaits you in Upstate South Carolina. If you’re looking for a little peace, consider booking during the quieter low season months. For more hustle and bustle, you may prefer to visit Upstate South Carolina in high season. Prices vary throughout the year. Your chosen location, property type, and amenities will impact the cost of your trip, too. The selection of properties we have chosen for you start as low as $120 per night. Rates vary depending on your travel dates, location, and amenities so make a search and you might find even better deals! **How to find incredible deals on Upstate South Carolina rentals** At Expedia, we put the best Upstate South Carolina vacation rentals in one place. All you need to do is take your pick. And as we offer book now, pay later options, as well as free cancellation on some properties, you can plan your trip with total peace of mind. You’ll always find a great deal with Expedia. To find some top Upstate South Carolina rental deals, enter your travel dates, and sort your search results by price. You can also filter by budget, so you only see accommodation in your ballpark. Next, add any filters you want—and just like that, you’ve built your dream Upstate South Carolina vacation. If you’re looking for a little inspiration, browse our latest incredible offers, or use the map to view all accommodation in and around Upstate South Carolina. And to unlock even more fantastic deals, bundle your accommodation, flights, and car rental together to save and book with Expedia in complete confidence. ## Explore a world of travel with Expedia - Trending destinations on Expedia.com - All accommodation types in Upstate South Carolina ### Trending destinations on Expedia.com - [Destin Vacation Rentals ](https://www.expedia.com/Destin-Vacation-Rentals.d6906.Travel-Guide-VacationRentals) - [Panama City Vacation Rentals ](https://www.expedia.com/Panama-City-Beach-Vacation-Rentals.d8021.Travel-Guide-VacationRentals) - [Hilton Head Vacation Rentals ](https://www.expedia.com/Hilton-Head-Island-Vacation-Rentals.d601684.Travel-Guide-VacationRentals) - [Gulf Shores Vacation Rentals ](https://www.expedia.com/Gulf-Shores-Vacation-Rentals.d603078.Travel-Guide-VacationRentals) - [Key West Vacation Rentals ](https://www.expedia.com/Key-West-Vacation-Rentals.d1187.Travel-Guide-VacationRentals) - [Gatlinburg Vacation Rentals ](https://www.expedia.com/Gatlinburg-Vacation-Rentals.d7474.Travel-Guide-VacationRentals) - 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