Title: Top 10 Hotels in Worthington, MO from $66 - Competitive Prices | Expedia.com

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## Go beyond your typical stay in Worthington

Pet friendly

[](https://www.expedia.com/Hotel-Search?destination=Worthington%2C+Missouri%2C+United+States+of+America&regionId=553248634983347772&latLong=40.40836%2C-92.688806&adults=2&startDate=2026-03-18&d1=2026-03-18&endDate=2026-03-20&d2=2026-03-20&amenities=PETS)

## Check prices for these dates

Tonight

[Mar 4 - Mar 5](https://www.expedia.com/Hotel-Search?regionId=553248634983347772&startDate=2026-03-04&endDate=2026-03-05&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

Tomorrow

[Mar 5 - Mar 6](https://www.expedia.com/Hotel-Search?regionId=553248634983347772&startDate=2026-03-05&endDate=2026-03-06&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

This weekend

[Mar 6 - Mar 8](https://www.expedia.com/Hotel-Search?regionId=553248634983347772&startDate=2026-03-06&endDate=2026-03-08&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

Next weekend

[Mar 13 - Mar 15](https://www.expedia.com/Hotel-Search?regionId=553248634983347772&startDate=2026-03-13&endDate=2026-03-15&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

## Our top choices for Worthington hotels

![Dining](https://images.trvl-media.com/lodging/1000000/30000/20500/20482/8a5baebb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/1000000/30000/20500/20482/1e205061.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/1000000/30000/20500/20482/w1021h682x0y0-c9b85e2f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/1000000/30000/20500/20482/b08ddc86.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Quality Inn Kirksville

[](https://www.expedia.com/Macon-Hotels-Quality-Inn-Kirksville.h20482.Hotel-Information)

Kirksville

7.6/10

Good

(397 reviews)

"The staff was friendly and provided excellent service!"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Don

$63 nightly

$71 total

Mar 17 - Mar 18

Total with taxes and fees

[](https://www.expedia.com/Macon-Hotels-Quality-Inn-Kirksville.h20482.Hotel-Information)

![Free daily buffet breakfast](https://images.trvl-media.com/lodging/1000000/130000/123600/123590/fd2e50c6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Reception](https://images.trvl-media.com/lodging/1000000/130000/123600/123590/9c660a01.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Room, 2 Double Beds, Non Smoking | Pillowtop beds, desk, blackout drapes, free cribs/infant beds](https://images.trvl-media.com/lodging/1000000/130000/123600/123590/adba1fe4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/130000/123600/123590/08bb1016.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Super 8 by Wyndham Kirksville-University Area

[](https://www.expedia.com/Macon-Hotels-Country-Club-Inn-Suites.h123590.Hotel-Information)

Kirksville

9.2/10

Wonderful

(175 reviews)

"Great breakfast let me check in early was very nice "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Jamie

$60 nightly

$67 total

Mar 22 - Mar 23

Total with taxes and fees

[](https://www.expedia.com/Macon-Hotels-Country-Club-Inn-Suites.h123590.Hotel-Information)

![Fridge, microwave, coffee/tea maker](https://images.trvl-media.com/lodging/1000000/30000/22200/22159/9afc2091.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Desk, bed sheets, alarm clocks](https://images.trvl-media.com/lodging/1000000/30000/22200/22159/a7e2219f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/1000000/30000/22200/22159/9b5928a5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Fridge, microwave, coffee/tea maker](https://images.trvl-media.com/lodging/1000000/30000/22200/22159/e004f75c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Knights Inn Kirksville

[](https://www.expedia.com/Macon-Hotels-Knights-Inn-Kirksville.h22159.Hotel-Information)

Kirksville

7.2/10

Good

(251 reviews)

"Room was clean… quiet… "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Jennifer

$64 nightly

$72 total

Mar 12 - Mar 13

Total with taxes and fees

[](https://www.expedia.com/Macon-Hotels-Knights-Inn-Kirksville.h22159.Hotel-Information)

![Free daily buffet breakfast](https://images.trvl-media.com/lodging/19000000/18060000/18057900/18057874/17367649.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/19000000/18060000/18057900/18057874/4be7f63c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/19000000/18060000/18057900/18057874/ee47dad5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![In-room safe, desk, laptop workspace, blackout drapes](https://images.trvl-media.com/lodging/19000000/18060000/18057900/18057874/a8acc085.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Holiday Inn Express & Suites Kirksville - University Area by IHG

[](https://www.expedia.com/Macon-Hotels-Holiday-Inn-Express-Suites-Kirksville-University-Area.h18057874.Hotel-Information)

Kirksville

9.2/10

Wonderful

(520 reviews)

"Excellent service and stay"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Taylor

$119 nightly

$135 total

Mar 8 - Mar 9

Total with taxes and fees

[](https://www.expedia.com/Macon-Hotels-Holiday-Inn-Express-Suites-Kirksville-University-Area.h18057874.Hotel-Information)

![Indoor pool](https://images.trvl-media.com/lodging/1000000/10000/4100/4031/9821cb76.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Bar (on property)](https://images.trvl-media.com/lodging/1000000/10000/4100/4031/2180aea2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/1000000/10000/4100/4031/f3c5f510.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Desk, iron/ironing board, rollaway beds, free WiFi](https://images.trvl-media.com/lodging/1000000/10000/4100/4031/80d5a891.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Days Inn by Wyndham Kirksville

[](https://www.expedia.com/Macon-Hotels-Days-Inn-By-Wyndham-Kirksville.h4031.Hotel-Information)

Kirksville

6.6/10

(1,003 reviews)

"Room was clean, organized. Staff was welcoming "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Vaishali

$59 nightly

$66 total

Mar 12 - Mar 13

Total with taxes and fees

[](https://www.expedia.com/Macon-Hotels-Days-Inn-By-Wyndham-Kirksville.h4031.Hotel-Information)

![Lobby](https://images.trvl-media.com/lodging/20000000/20000000/19991900/19991846/c19d4fbf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/20000000/20000000/19991900/19991846/388c1302.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/20000000/20000000/19991900/19991846/0d60e323.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/20000000/20000000/19991900/19991846/68baa0ca.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Hampton Inn Kirksville

[](https://www.expedia.com/Macon-Hotels-Hampton-Inn-Kirksville.h19991846.Hotel-Information)

Kirksville

9.2/10

Wonderful

(599 reviews)

"Better than a typical hotel, premium bedding, great lobby space for families to gather."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Lynn

$123 nightly

$139 total

Apr 5 - Apr 6

Total with taxes and fees

[](https://www.expedia.com/Macon-Hotels-Hampton-Inn-Kirksville.h19991846.Hotel-Information)

![Superior Studio Suite, 1 King Bed, Non Smoking | Jetted tub](https://images.trvl-media.com/lodging/1000000/130000/125500/125458/b428c708.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Free daily continental breakfast](https://images.trvl-media.com/lodging/1000000/130000/125500/125458/a2f46102.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/1000000/130000/125500/125458/33e2a913.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Courtyard](https://images.trvl-media.com/lodging/1000000/130000/125500/125458/fe067a47.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Baymont by Wyndham Kirksville University Area

[](https://www.expedia.com/Macon-Hotels-Baymont-By-Wyndham-Kirksville-University-Area.h125458.Hotel-Information)

Kirksville

7.6/10

Good

(901 reviews)

"Great stay. Only negative was the dirty roll away bed sheet. Great breakfast and super staff."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Aime

$59 nightly

$67 total

Mar 22 - Mar 23

Total with taxes and fees

[](https://www.expedia.com/Macon-Hotels-Baymont-By-Wyndham-Kirksville-University-Area.h125458.Hotel-Information)

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

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## Top Worthington Hotel Reviews

![Hampton Inn Kirksville](https://images.trvl-media.com/lodging/20000000/20000000/19991900/19991846/c19d4fbf_y.jpg)

### Hampton Inn Kirksville

6/10 Okay

"We’ve stayed here several times while visiting Kirksville. The pool has been “out of order” with the door to the outside propped open (even in the middle of winter) every single stay until this one, when it was open for about two hours in the evening. The water was so cold we couldn’t stand to be in it, but somehow still enough humidity in the room that the ceiling was literally dripping. The rooms are great, clean, comfortable. But the noise level from the hallways and rooms above/below is bad, and the free breakfast offered is nothing special. For the price, I at least want the amenities I paid for."

[](https://expedia.com/Macon-Hotels-Hampton-Inn-Kirksville.h19991846.Hotel-Information)

![Super 8 by Wyndham Kirksville-University Area](https://images.trvl-media.com/lodging/1000000/130000/123600/123590/fd2e50c6_y.jpg)

### Super 8 by Wyndham Kirksville-University Area

10/10 Excellent

"Great price for a clean room and free hot breakfast! Property is older and a little janky (our toilet paper holder was coming loose from the wall, raw edges on the newly installed vanity/sink, VERY LOUD heat/AC unit as others have mentioned), BUT the room was clean, staff was incredibly helpful, clean and comfortable bed/pillows, and free breakfast in the morning. We’ve stayed at more expensive hotels in Kirksville at least a dozen times and have regularly been disappointed in lack of amenities, unimpressive breakfast options, and crappy staff. Super 8 is economical and convenient, staff is wonderful, and it will absolutely be our first choice every time we visit Kirksville. "

[](https://expedia.com/Macon-Hotels-Country-Club-Inn-Suites.h123590.Hotel-Information)

![Quality Inn Kirksville](https://images.trvl-media.com/lodging/1000000/30000/20500/20482/8a5baebb_y.jpg)

### Quality Inn Kirksville

2/10 Terrible

"Rude staff, booked a room, the games got switched to a day earlier, staff would not move the reservation up one day. It was booked <12hours. Very uncooperative. Would not recommend."

[](https://expedia.com/Macon-Hotels-Quality-Inn-Kirksville.h20482.Hotel-Information)

![Days Inn by Wyndham Kirksville](https://images.trvl-media.com/lodging/1000000/10000/4100/4031/9821cb76_y.jpg)

### Days Inn by Wyndham Kirksville

10/10 Excellent

"Everything "

[](https://expedia.com/Macon-Hotels-Days-Inn-By-Wyndham-Kirksville.h4031.Hotel-Information)

![Holiday Inn Express & Suites Kirksville - University Area by IHG](https://images.trvl-media.com/lodging/19000000/18060000/18057900/18057874/17367649_y.jpg)

### Holiday Inn Express & Suites Kirksville - University Area by IHG

10/10 Excellent

"Clean and spacious rooms. Good breakfast with lots of tables to eat at."

[](https://expedia.com/Macon-Hotels-Holiday-Inn-Express-Suites-Kirksville-University-Area.h18057874.Hotel-Information)

![Country Cabin In The Woods](https://images.trvl-media.com/lodging/105000000/104310000/104308300/104308277/529c3996_y.jpg)

### Country Cabin In The Woods

10/10 Excellent

"The cabin never disappoints. Highly recommend. Hope to stay there again soon."

[](https://expedia.com/Kirksville-Hotels-Country-Cabin-In-The-Woods.h104308277.Hotel-Information)

![Country's Edge Retreat](https://images.trvl-media.com/lodging/121000000/120070000/120065000/120064921/fb131a5b_y.jpg)

### Country's Edge Retreat

10/10 Excellent

"Clean, neat and peaceful location. Wonderfully quiet location, ten minute drive from food shopping and activities. Worth the stay."

[](https://expedia.com/Greentop-Hotels-Countrys-Edge-Retreat.h120064921.Hotel-Information)

![Knights Inn Kirksville](https://images.trvl-media.com/lodging/1000000/30000/22200/22159/e004f75c_y.jpg)

### Knights Inn Kirksville

2/10 Terrible

"This actually shows a 8.2 which is more like a 2.8 it says continual breakfast and there is none!! It is a pass through room and both doors had gaps around them you could actually see outside. Stains above both beds no cover on exhaust fan in bathroom and did not work had a Walmart bag stuffed in the vent, smoke detector had not battery and door was broke on it. Had a nice frig but no way to plug it into a three pin outlet unless you took it to the bathroom. Heating/A/C unit was green with mold. With all that said the room and bed was clean but cold as crap especially when it got -7 outside. Paid for three nights could not handle the room did not even stay the last night in fear of freezing to death. Save yourself a headache and go some where else!!!"

[](https://expedia.com/Macon-Hotels-Knights-Inn-Kirksville.h22159.Hotel-Information)

![Little Blue Cottage - Charming 1-bedroom cottage in Kirksville](https://images.trvl-media.com/lodging/109000000/108400000/108390200/108390143/f734b584_y.jpg)

### Little Blue Cottage - Charming 1-bedroom cottage in Kirksville

10/10 Excellent

"Everything was excellent!"

[](https://expedia.com/Kirksville-Hotels-Little-Blue-Cottage-Charming-1-Bedroom-Cottage-In-Kirksville.h108390143.Hotel-Information)

## More cheap stays in Worthington

![Days Inn by Wyndham Kirksville](https://images.trvl-media.com/lodging/1000000/10000/4100/4031/9821cb76_y.jpg?impolicy=resizecrop&rw=402&ra=fit)

### Days Inn by Wyndham Kirksville

3805 S Baltimore St Kirksville MO

$59 nightly

$66 total

Mar 12 - Mar 13

Total with taxes and fees

6.6/10 (1,003 reviews)

[](https://expedia.com/Macon-Hotels-Days-Inn-By-Wyndham-Kirksville.h4031.Hotel-Information)

![Super 8 by Wyndham Kirksville-University Area](https://images.trvl-media.com/lodging/1000000/130000/123600/123590/fd2e50c6_y.jpg?impolicy=resizecrop&rw=402&ra=fit)

### Super 8 by Wyndham Kirksville-University Area

1101 Country Club Dr Kirksville MO

$60 nightly

$67 total

Mar 22 - Mar 23

Total with taxes and fees

9.2/10 Wonderful! (175 reviews)

[](https://expedia.com/Macon-Hotels-Country-Club-Inn-Suites.h123590.Hotel-Information)

![Quality Inn Kirksville](https://images.trvl-media.com/lodging/1000000/30000/20500/20482/8a5baebb_y.jpg?impolicy=resizecrop&rw=402&ra=fit)

### Quality Inn Kirksville

2209 N. Baltimore Street Kirksville MO

$63 nightly

$71 total

Mar 17 - Mar 18

Total with taxes and fees

7.6/10 Good! (397 reviews)

[](https://expedia.com/Macon-Hotels-Quality-Inn-Kirksville.h20482.Hotel-Information)

![Holiday Inn Express & Suites Kirksville - University Area by IHG](https://images.trvl-media.com/lodging/19000000/18060000/18057900/18057874/17367649_y.jpg?impolicy=resizecrop&rw=402&ra=fit)

### Holiday Inn Express & Suites Kirksville - University Area by IHG

2523 South Franklin St. Kirksville MO

$119 nightly

$135 total

Mar 8 - Mar 9

Total with taxes and fees

9.2/10 Wonderful! (520 reviews)

[](https://expedia.com/Macon-Hotels-Holiday-Inn-Express-Suites-Kirksville-University-Area.h18057874.Hotel-Information)

![Hampton Inn Kirksville](https://images.trvl-media.com/lodging/20000000/20000000/19991900/19991846/c19d4fbf_y.jpg?impolicy=resizecrop&rw=402&ra=fit)

### Hampton Inn Kirksville

2604 N. Baltimore Street Kirksville MO

$123 nightly

$139 total

Apr 5 - Apr 6

Total with taxes and fees

9.2/10 Wonderful! (599 reviews)

[](https://expedia.com/Macon-Hotels-Hampton-Inn-Kirksville.h19991846.Hotel-Information)

![Thousand Hills](https://images.trvl-media.com/lodging/107000000/106800000/106792500/106792431/855824fb_y.jpg?impolicy=resizecrop&rw=402&ra=fit)

### Thousand Hills

20431 Missouri 157 Kirksville MO

[Get rates](https://expedia.com/Hotel-Search?startDate=3%2F19%2F2026&endDate=3%2F20%2F2026&selected=106792431&PinnedHotelID=106792431&HadPinnedHotel=true&regionId=553248634983347772)

9/10 Wonderful! (14 reviews)

[](https://expedia.com/Kirksville-Hotels-Thousand-Hills.h106792431.Hotel-Information)

## Hotels in Worthington with star-rating

![2 Star Hotels](https://images.trvl-media.com/lodging/92000000/91830000/91828000/91827910/6717a2ac_z.jpg)

2 Star Hotels

10 properties

[](https://expedia.com/2Star-Worthington-Hotels.s20-0-d553248634983347772.Travel-Guide-Filter-Hotels)

## Frequently asked questions

### What is the best area to stay in Worthington?

> This central area offers a pleasant experience for visitors, with many local shops, eateries, and the historic Worthington Village Green within easy walking distance. The architecture here reflects the town's heritage, providing a comfortable and inviting setting.
> 
>   
> Couples will find downtown Worthington appealing for its accessible dining options and the opportunity for leisurely strolls through the Village Green.

### When is the best time to go to Worthington?

> During these months, you'll experience comfortable temperatures, typically ranging from the 60s to high 70s Fahrenheit, with less humidity than the peak summer months. This makes it ideal for exploring Worthington's natural surroundings, such as the area's numerous walking trails and parks, without the discomfort of extreme heat or cold.
> 
>   
> Couples looking for a relaxing getaway will appreciate the mild weather for enjoying leisurely strolls through the town center or taking scenic drives through the surrounding countryside. Many local events and farmers' markets also take place during these shoulder seasons, offering a chance to experience the community's local offerings.
> 
>   
> Travelers seeking a peaceful escape will find the quiet beauty of Worthington during these times particularly appealing.

### Can I cancel my hotel reservation on Expedia?

### How can I save on a Worthington hotel booking with Expedia?

> \*Excludes taxes and fees. OneKeyCash is not redeemable for cash and can only be used on Expedia, Hotels.com and Vrbo.

### How much is the nightly rate at a Worthington hotel?

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