A historic yellow and red church with arched doorways and a prominent bell tower.

Zona Centro Vacations from $324

Book a Hotel + Flight or Car together to unlock savings

  • Plan, book, travel with confidence

  • Better together

    Save up to $2,000 when you book a flight and hotel together*
  • Find the right fit

    With over 300,000 hotels worldwide, it's easy to create a perfect package
  • Rest easy

    Plan, book, and manage your trip all in one place

Your Zona Centro Vacation

Our Zona Centro vacation packages are a time-saving and convenient way to plan and reserve your next retreat. Experience the magic of this unique neighborhood without the fuss of planning everything yourself. Some top nearby attractions to see during your trip to Zona Centro include San Cristóbal de las Casas Cathedral, Guadalupe Church and Plaza 31 de Marzo. No matter what your ideal Zona Centro vacation may look like, you can turn it into reality with Expedia.

The Latest Zona Centro Vacation Packages

Price found within the past 48 hours. Click for updated prices.
  • Jan 14 - Jan 18

    Hotel Maria Eugenia Tuxtla Gutierrez + Flight

    Tuxtla Gutiérrez Centro
    4 nights
    3.0 star property
    7.8/10 - Good (329 reviews)
    "Breakfast, no refills on coffee and rude personnel"
    Reviewed November 8, 2026
    Roundtrip • Tijuana (TIJ) - Tuxtla Gutierrez (TGZ)
    TIJ - TGZ • 1 stop TGZ - TIJ • 1 stop
    $508
    $324
    per traveler
    found 7 hours ago
    Hotel Maria Eugenia Tuxtla Gutierrez
  • Dec 26 - Jan 2

    HOTEL PLAZA 79 + Flight

    Santa Lucía
    6 nights
    3.5 star property
    9.4/10 - Exceptional (129 reviews)
    "El dia que llegamos el elevador esraba descompuesto, faltan letreros en estacionamiento, que indiquen ubicación de Recepción. Habitacion 100% excepcional."
    Reviewed November 8, 2026
    Roundtrip • Ciudad Juárez (CJS) - Tuxtla Gutierrez (TGZ)
    CJS - TGZ • 1 stop TGZ - CJS • 1 stop
    $5,205
    $2,927
    per traveler
    found 13 hours ago
    HOTEL PLAZA 79
  • Dec 26 - Jan 2

    Casa del Alma Hotel Boutique & Spa + Flight

    Zona Centro
    6 nights
    4.0 star property
    9.6/10 - Exceptional (348 reviews)
    "Great location, clean, staff very nice. Excellent small hotel."
    Reviewed October 7, 2026
    Roundtrip • Ciudad Juárez (CJS) - Tuxtla Gutierrez (TGZ)
    CJS - TGZ • 1 stop TGZ - CJS • 1 stop
    $2,323
    $1,604
    per traveler
    found 13 hours ago
    Casa del Alma Hotel Boutique & Spa
  • Jan 14 - Jan 18

    Hotel Molino de la Alborada + Flight

    San Cristóbal de las Casas
    4 nights
    3.0 star property
    7.6/10 - Good (15 reviews)
    "Hilltop hacienda, peacefully out of the hustle and bustle of the town. Hotel has fireplaces for heat, the breakfast was good, staff was helpful and friendly. A little out of the way but cabs here are very inexpensive."
    Reviewed March 22, 2017
    Roundtrip • Tijuana (TIJ) - Tuxtla Gutierrez (TGZ)
    TIJ - TGZ • 1 stop TGZ - TIJ • 1 stop
    $472
    $359
    per traveler
    found 7 hours ago
    Hotel Molino de la Alborada
  • Feb 3 - Feb 8

    Capital O Hotel Aurora, Tuxtla Gutiérrez + Flight

    Tuxtla Gutiérrez Centro
    5 nights
    2.5 star property
    8.8/10 - Excellent (89 reviews)
    "El colchón es súper cómodo, la regadera el agua sale caliente rápido, el cuarto está limpio. Fueron muy amables con nosotros, seguramente volveremos a quedarnos aquí cuando estemos en Tuxtla."
    Reviewed October 18, 2026
    Roundtrip • Dallas (DFW) - Tuxtla Gutierrez (TGZ)
    DFW - TGZ • 1 stop TGZ - DFW • 1 stop
    $613
    $471
    per traveler
    found 1 day ago
    Capital O Hotel Aurora, Tuxtla Gutiérrez

Where to stay in Zona Centro

Find the best Zona Centro areas and neighborhoods for the activities you enjoy most.

Santa Lucía

While visiting Santa Lucía, you might make a stop by sights like Santo Domingo Handicraft Market and Arches of Carmen.

Barrio de Guadalupe

Barrio de Guadalupe might not have many top sights, but Na Bolom Cultural Museum and Santo Domingo Handicraft Market are two attractions nearby that you can check out.

Barrio de La Merced

While visiting Barrio de La Merced, you might make a stop by sights like Amber Museum of Chiapas and Regional Costume Museum.

Barrio del Cerrillo

If you're spending some time in Barrio del Cerrillo, Na Bolom Cultural Museum and Ex-Convent of Santo Domingo are top sights worth seeing.

Barrio de Mexicanos

Barrio de Mexicanos might not have many top sights, but Ex-Convent of Santo Domingo and Mesoamerican Museum of Jade are two attractions nearby that you can check out.

Discover the most popular places to visit in Zona Centro

What to do near Zona Centro

Zona Centro Hotel Deals

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.