Title: The Best 5 Star Hotels in Colon from $140 | Expedia.com

[Colon Travel Guide](https://expedia.com/Colon.dx601867)[Hotels in Colon](https://expedia.com/Colon-Hotels.d601867.Travel-Guide-Hotels)[Vacation Rentals in Colon](https://expedia.com/Colon-Vacation-Rentals.d601867.Travel-Guide-VacationRentals)[Flights to Colon](https://expedia.com/Cheap-Flights-To-Colon.d601867.Travel-Guide-Flights)[Things to do in Colon](https://expedia.com/Things-To-Do-In-Colon.d601867.Travel-Guide-Activities)[Car Rentals in Colon](https://expedia.com/Car-Rentals-In-Colon.d601867.Car-Rental-Guide)[Colon Vacation Packages](https://expedia.com/Colon.d601867.Destination-Travel-Guides)

![Adobe](https://images.trvl-media.com/place/601867/943091b0-9dea-43c5-9bcc-64801cfef8b7.jpg?impolicy=fcrop&w=1200&h=500&q=medium)

![](https://images.trvl-media.com/place/601867/943091b0-9dea-43c5-9bcc-64801cfef8b7.jpg?impolicy=fcrop&w=1200&h=500&q=medium)

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## Check availability on Colon 5 Star Hotels

Tonight

[Feb 5 - Feb 6](https://www.expedia.com/Hotel-Search?regionId=601867&startDate=2026-02-05&endDate=2026-02-06&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

Tomorrow

[Feb 6 - Feb 7](https://www.expedia.com/Hotel-Search?regionId=601867&startDate=2026-02-06&endDate=2026-02-07&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

This weekend

[Feb 6 - Feb 8](https://www.expedia.com/Hotel-Search?regionId=601867&startDate=2026-02-06&endDate=2026-02-08&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

Next weekend

[Feb 13 - Feb 15](https://www.expedia.com/Hotel-Search?regionId=601867&startDate=2026-02-13&endDate=2026-02-15&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

## Our top choices for Colon 5-star hotels

![Outdoor pool, sun loungers](https://images.trvl-media.com/lodging/4000000/3910000/3900400/3900395/6f5f0f4f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Penthouse (In the heart of the City) | Minibar, in-room safe, desk, laptop workspace](https://images.trvl-media.com/lodging/4000000/3910000/3900400/3900395/c6c3b77c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Reception](https://images.trvl-media.com/lodging/4000000/3910000/3900400/3900395/f2fa3d9d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/4000000/3910000/3900400/3900395/096c0ccc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Hotel Riu Plaza Panama

[](https://www.expedia.com/Panama-City-Hotels-Hotel-Riu-Plaza-Panama.h3900395.Hotel-Information)

Bella Vista

9.0/10

Wonderful

(4,917 reviews)

" Nice hotel and great location "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Wajdi

$138 nightly

$151 total

Mar 3 - Mar 4

Total with taxes and fees

[](https://www.expedia.com/Panama-City-Hotels-Hotel-Riu-Plaza-Panama.h3900395.Hotel-Information)

![2 bars/lounges, poolside bar](https://images.trvl-media.com/lodging/5000000/4960000/4952100/4952056/bd4cfae6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/5000000/4960000/4952100/4952056/4a63a156.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![View from property](https://images.trvl-media.com/lodging/5000000/4960000/4952100/4952056/e7e98c5e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/5000000/4960000/4952100/4952056/1124b3de.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Waldorf Astoria Panama

[](https://www.expedia.com/Panama-City-Hotels-Waldorf-Astoria-Panama.h4952056.Hotel-Information)

Bella Vista

9.0/10

Wonderful

(1,002 reviews)

"Staff was super nice and room was great we also ate on the rooftop and food was great!"

![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg)

Tim

$221 nightly

$243 total

Mar 7 - Mar 8

Total with taxes and fees

[](https://www.expedia.com/Panama-City-Hotels-Waldorf-Astoria-Panama.h4952056.Hotel-Information)

![2 restaurants, local cuisine](https://images.trvl-media.com/lodging/22000000/21320000/21314100/21314035/5dc0b3d1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/22000000/21320000/21314100/21314035/1175365b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Urban Suite,1 King, Partial City view | In-room safe, blackout drapes, iron/ironing board](https://images.trvl-media.com/lodging/22000000/21320000/21314100/21314035/0b373179.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Penthouse I, Suite, 1 King, Partial City view | Living room | LCD TV, iPod dock](https://images.trvl-media.com/lodging/22000000/21320000/21314100/21314035/c594bc6e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### W Panama

[](https://www.expedia.com/Panama-City-Hotels-W-Panama.h21314035.Hotel-Information)

Bella Vista

9.0/10

Wonderful

(1,000 reviews)

"Second time staying and it was flawless."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Anthony

$183 nightly

$202 total

Mar 7 - Mar 8

Total with taxes and fees

[](https://www.expedia.com/Panama-City-Hotels-W-Panama.h21314035.Hotel-Information)

![4 outdoor pools, free cabanas, pool umbrellas](https://images.trvl-media.com/lodging/5000000/4110000/4109200/4109123/fb42dbf6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Egyptian cotton sheets, premium bedding, down comforters, pillowtop beds](https://images.trvl-media.com/lodging/5000000/4110000/4109200/4109123/08d313d2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![4 outdoor pools, free cabanas, pool umbrellas](https://images.trvl-media.com/lodging/5000000/4110000/4109200/4109123/0babe4e3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/5000000/4110000/4109200/4109123/w3996h2667x4y0-a167c2ea.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### JW Marriott Panama

[](https://www.expedia.com/Panama-City-Hotels-JW-Marriott-Panama.h4109123.Hotel-Information)

San Francisco

9.0/10

Wonderful

(1,006 reviews)

"Beautiful hotel, great service. Breakfast buffet is amazing. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Tamara

$259 nightly

$285 total

Mar 7 - Mar 8

Total with taxes and fees

[](https://www.expedia.com/Panama-City-Hotels-JW-Marriott-Panama.h4109123.Hotel-Information)

![Room, 1 King Bed, Balcony, Oceanfront (Magnifique) | Premium bedding, down comforters, pillowtop beds, minibar](https://images.trvl-media.com/lodging/73000000/72990000/72981200/72981169/ccd122a6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![2 bars/lounges, swim-up bar, poolside bar](https://images.trvl-media.com/lodging/73000000/72990000/72981200/72981169/8ddbf6dd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/73000000/72990000/72981200/72981169/88416317.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/73000000/72990000/72981200/72981169/c28c4592.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Sofitel Legend Casco Viejo, Panama City 

[](https://www.expedia.com/Panama-City-Hotels-Sofitel-Legend-Casco-Viejo.h72981169.Hotel-Information)

Casco Viejo

9.8/10

Exceptional

(587 reviews)

"Beautiful place"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Jose

$374 nightly

$411 total

Feb 23 - Feb 24

Total with taxes and fees

[](https://www.expedia.com/Panama-City-Hotels-Sofitel-Legend-Casco-Viejo.h72981169.Hotel-Information)

![Sports facility](https://images.trvl-media.com/lodging/6000000/5940000/5938200/5938139/99beffbc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![4 restaurants, breakfast, lunch served; American cuisine](https://images.trvl-media.com/lodging/6000000/5940000/5938200/5938139/17d1dc17.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby sitting area](https://images.trvl-media.com/lodging/6000000/5940000/5938200/5938139/03b3b6f0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![4 restaurants, breakfast, lunch served; American cuisine](https://images.trvl-media.com/lodging/6000000/5940000/5938200/5938139/eb1560c2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Hilton Panama

[](https://www.expedia.com/Panama-City-Hotels-Hilton-Panama.h5938139.Hotel-Information)

Bella Vista

8.8/10

Excellent

(1,004 reviews)

"Huge hotel wit"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Katya

$211 nightly

$232 total

Mar 7 - Mar 8

Total with taxes and fees

[](https://www.expedia.com/Panama-City-Hotels-Hilton-Panama.h5938139.Hotel-Information)

![3 outdoor pools, pool umbrellas, sun loungers](https://images.trvl-media.com/lodging/5000000/4670000/4668700/4668643/e50f6f0f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![View from property](https://images.trvl-media.com/lodging/5000000/4670000/4668700/4668643/cfdbe00f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby sitting area](https://images.trvl-media.com/lodging/5000000/4670000/4668700/4668643/ed6fb5fd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![3 outdoor pools, pool umbrellas, sun loungers](https://images.trvl-media.com/lodging/5000000/4670000/4668700/4668643/0e5b4d5c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### The Westin Playa Bonita Panama

[](https://www.expedia.com/Panama-City-Hotels-The-Westin-Playa-Bonita-Panama.h4668643.Hotel-Information)

Veracruz

8.0/10

Very Good

(1,011 reviews)

"Beautiful property and amazing staff"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

CARMEN

$237 nightly

$260 total

Mar 9 - Mar 10

Total with taxes and fees

[](https://www.expedia.com/Panama-City-Hotels-The-Westin-Playa-Bonita-Panama.h4668643.Hotel-Information)

![Lobby lounge](https://images.trvl-media.com/lodging/1000000/530000/527200/527169/4235e7f0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Outdoor pool, free cabanas, pool umbrellas](https://images.trvl-media.com/lodging/1000000/530000/527200/527169/9e56ccf3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby lounge](https://images.trvl-media.com/lodging/1000000/530000/527200/527169/d4b0e49b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Breakfast, lunch, dinner served; pool views](https://images.trvl-media.com/lodging/1000000/530000/527200/527169/5ca43e2f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Renaissance Panama City Hotel 

[](https://www.expedia.com/Panama-City-Hotels-Renaissance-Panama-City-Hotel.h527169.Hotel-Information)

Bella Vista

9.0/10

Wonderful

(142 reviews)

"Very good hotel, well located. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Andrés

$127 nightly

$140 total

Feb 16 - Feb 17

Total with taxes and fees

[](https://www.expedia.com/Panama-City-Hotels-Renaissance-Panama-City-Hotel.h527169.Hotel-Information)

![Couples treatment rooms, sauna, steam room, body treatments](https://images.trvl-media.com/lodging/1000000/70000/69700/69638/1700edf5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Yoga](https://images.trvl-media.com/lodging/1000000/70000/69700/69638/79b76059.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Breakfast, lunch, dinner served; international cuisine ](https://images.trvl-media.com/lodging/1000000/70000/69700/69638/620cc150.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Outdoor pool, sun loungers](https://images.trvl-media.com/lodging/1000000/70000/69700/69638/8e0cdd04.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Bristol Panama, a Registry Collection Hotel

[](https://www.expedia.com/Panama-City-Hotels-Bristol-Panama.h69638.Hotel-Information)

Bella Vista

9.4/10

Exceptional

(1,003 reviews)

"All was perfect for our Christmas vacation - staff food and rooms - would definitely stay here again"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

PROBIR MAYUR

$209 nightly

$230 total

Feb 27 - Feb 28

Total with taxes and fees

[](https://www.expedia.com/Panama-City-Hotels-Bristol-Panama.h69638.Hotel-Information)

![View from property](https://images.trvl-media.com/lodging/21000000/20960000/20958600/20958573/3972c3df.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![View from property](https://images.trvl-media.com/lodging/21000000/20960000/20958600/20958573/166e4001.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/21000000/20960000/20958600/20958573/db85bc00.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![2 restaurants, breakfast, lunch served; local and international cuisine](https://images.trvl-media.com/lodging/21000000/20960000/20958600/20958573/c579d87e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City

[](https://www.expedia.com/Panama-City-Hotels-The-Santa-Maria.h20958573.Hotel-Information)

Juan Diaz

9.6/10

Exceptional

(660 reviews)

"As usual the stay was amazing in this hotel"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Jose

$226 nightly

$248 total

Mar 7 - Mar 8

Total with taxes and fees

[](https://www.expedia.com/Panama-City-Hotels-The-Santa-Maria.h20958573.Hotel-Information)

![View from property](https://images.trvl-media.com/lodging/6000000/5080000/5074300/5074269/449ce738.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![View from property](https://images.trvl-media.com/lodging/6000000/5080000/5074300/5074269/0b1e4b11_edited_cdf5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![4 bars/lounges, tapas bar](https://images.trvl-media.com/lodging/6000000/5080000/5074300/5074269/7368cd10.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Hypo-allergenic bedding, in-room safe, desk, blackout drapes](https://images.trvl-media.com/lodging/6000000/5080000/5074300/5074269/90613175.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Megapolis Hotel Panamá

[](https://www.expedia.com/Panama-City-Hotels-Megapolis-Hotel-Panama.h5074269.Hotel-Information)

San Francisco

8.4/10

Very Good

(1,001 reviews)

"Great stay! Very safe!"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

MARVIN

[](https://www.expedia.com/Panama-City-Hotels-Megapolis-Hotel-Panama.h5074269.Hotel-Information)

![Lobby](https://images.trvl-media.com/lodging/2000000/1420000/1410100/1410053/e6ea2c2d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Outdoor pool](https://images.trvl-media.com/lodging/2000000/1420000/1410100/1410053/9750e503.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/2000000/1420000/1410100/1410053/67ba0beb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Restaurant](https://images.trvl-media.com/lodging/2000000/1420000/1410100/1410053/b050eac6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Waymore Hotel Spa and Casino

[](https://www.expedia.com/Panama-City-Hotels-Veneto-Hotel-Casino.h1410053.Hotel-Information)

Bella Vista

6.2/10

(1,000 reviews)

"It has a nice casino and it's very conveniently located. Breakfast was very good as well. Staff very helpful and attention oriented. Good experience "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Aldo

[](https://www.expedia.com/Panama-City-Hotels-Veneto-Hotel-Casino.h1410053.Hotel-Information)

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## Explore similar 4-star hotels

Many 4-star hotels have the same amenities as 5-star hotels. See all 4-star hotels in Colon.

![Megapolis Hotel Panamá](https://images.trvl-media.com/lodging/92000000/92000000/91995600/91995575/4aee4896_y.jpg?impolicy=resizecrop&rw=402&ra=fit)

### Megapolis Hotel Panamá

Avenida Balboa Panama City 

$205 nightly

$226 total

Feb 11 - Feb 12

Total with taxes and fees

8.4/10 Very Good! (1,406 reviews)

[](https://expedia.com/Panama-City-Hotels-Megapolis-Hotel-Panama.h91995575.Hotel-Information)

![Las Americas Golden Tower Panama](https://images.trvl-media.com/lodging/10000000/9680000/9675300/9675263/83f7ceed_y.jpg?impolicy=resizecrop&rw=402&ra=fit)

### Las Americas Golden Tower Panama

Av. Balboa con Calle 53 Panama City Panama

$168 nightly

$186 total

Feb 24 - Feb 25

Total with taxes and fees

8.8/10 Excellent! (1,001 reviews)

[](https://expedia.com/Panama-City-Hotels-Las-Americas-Golden-Tower-Panama.h9675263.Hotel-Information)

![Marriott Panama Hotel](https://images.trvl-media.com/lodging/7000000/6100000/6099300/6099287/b61be540_y.jpg?impolicy=resizecrop&rw=402&ra=fit)

### Marriott Panama Hotel

Roosevelt Ave., Allbrook Mall Panama City Panama

$161 nightly

$177 total

Feb 20 - Feb 21

Total with taxes and fees

9/10 Wonderful! (1,003 reviews)

[](https://expedia.com/Panama-City-Hotels-Marriott-Panama-Hotel.h6099287.Hotel-Information)

Still don't see what you're looking for?

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You can also use these popular filters to refine your search.

[Pool](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=2%2F7%2F2026&endDate=2%2F8%2F2026&regionId=601867&star=50&star=50&amenities=POOL)[Spa](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=2%2F7%2F2026&endDate=2%2F8%2F2026&regionId=601867&star=50&star=50&amenities=SPA_ON_SITE)[Hot tub](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=2%2F7%2F2026&endDate=2%2F8%2F2026&regionId=601867&star=50&star=50&amenities=HOT_TUB)[Breakfast included](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=2%2F7%2F2026&endDate=2%2F8%2F2026&regionId=601867&star=50&star=50&amenities=FREE_BREAKFAST)[Waterpark](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=2%2F7%2F2026&endDate=2%2F8%2F2026&regionId=601867&star=50&star=50&amenities=WATER_PARK)

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

## Learn more about Colon

Explore the colorful Zona Libre free trade zone for duty-free shopping and visit the historic Colon 2000 cruise port. Discover Panama's colonial history at Fort San Lorenzo, located on the Caribbean coast outside the city.

[See all hotels in Colon](https://www.expedia.com/Hotel-Search?startDate=2026-02-20&endDate=2026-02-21&adults=2&regionId=601867)

![Adobe](https://images.trvl-media.com/place/601867/943091b0-9dea-43c5-9bcc-64801cfef8b7.jpg?impolicy=fcrop&w=900&h=499&p=1&q=high)

## Top Colon Hotel Reviews

![Waldorf Astoria Panama](https://images.trvl-media.com/lodging/5000000/4960000/4952100/4952056/e7e98c5e_y.jpg)

### Waldorf Astoria Panama

10/10 Excellent

"Staff was super nice and room was great we also ate on the rooftop and food was great!"

[](https://expedia.com/Panama-City-Hotels-Waldorf-Astoria-Panama.h4952056.Hotel-Information)

![The Westin Playa Bonita Panama](https://images.trvl-media.com/lodging/5000000/4670000/4668700/4668643/6d441b5e_y.jpg)

### The Westin Playa Bonita Panama

10/10 Excellent

"Clean rooms "

[](https://expedia.com/Panama-City-Hotels-The-Westin-Playa-Bonita-Panama.h4668643.Hotel-Information)

![Hotel Riu Plaza Panama](https://images.trvl-media.com/lodging/4000000/3910000/3900400/3900395/1eaf88f5_y.jpg)

### Hotel Riu Plaza Panama

10/10 Excellent

"The breakfast"

[](https://expedia.com/Panama-City-Hotels-Hotel-Riu-Plaza-Panama.h3900395.Hotel-Information)

![W Panama](https://images.trvl-media.com/lodging/22000000/21320000/21314100/21314035/5dc0b3d1_y.jpg)

### W Panama

10/10 Excellent

"Clean room staff everything was amazing "

[](https://expedia.com/Panama-City-Hotels-W-Panama.h21314035.Hotel-Information)

## Find out more about Colon

There's nothing wrong with enjoying the finer things in life. Add an extra layer of luxury on your next trip to Colon by treating yourself to the best of the best when it comes to lodging. It's an ideal pairing. There's no reason to delay a getaway to Colon any longer. You'll join the multitudes of vacationers who have made Colon so fashionable recently. You can also expect excellent customer service from these hotels, so get ready to kick back and indulge. Don't wait any longer. Book one of Expedia's luxurious 5-star hotels in Colon and get ready to be pampered like never before.

### Book the Best Colon 5-Star Hotels

You'll have a wonderful time at one of these 5-star hotels. High-end restaurants, concierges, and pillow-fluffing are all at the ready. You're sure to find exactly the accommodation you need. You can also look forward to an outstanding experience and fantastic customer care, so get ready to kick back and indulge. How do you want to relax? A rejuvenating facial treatment to help your cares fall away? A concierge to help you suggest the next attraction to visit? Fluffy down pillows, lip-smacking main courses, and even space for your family pet in some cases...these hotels are one-of-a-kind. Don't want to take our word for it? Explore our listings and pick the perfect accommodation for your needs. 

You won't sleep and order room service the entire time, though. We hear you. From doing a bit of shopping to embracing the great outdoors, you'll never be bored on this retreat. Whatever you plan to do, the 5-star hotels in Colon are waiting for you to rest up after a busy day.

### Make Your Escape

The results are in, and Colon 5-star hotels are the place to be when you book your next vacation. If you've been dreaming about a vacation set here, then go ahead and book it. Expedia can help you land a great deal on accommodation. Don't put off your dream vacation any longer. Choose one of our Colon 5-star hotels today and relax in total tranquility tomorrow.

## Frequently asked questions

### How much does it cost to stay in a 5-star hotel in Colon?

> - Search for the lowest price per night from $177

### What makes a hotel 5 stars in Colon?

### Are there any 5-star all-inclusive resorts in Colon?

## Explore a world of travel with Expedia

- Lodging
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- Cars

- [Hotels near Colon Free Zone ](https://www.expedia.com/Colon-Free-Zone-Hotels.0-l6078503-0.Travel-Guide-Filter-Hotels)
- [Hotels near Colon Atlantic Passenger Station ](https://www.expedia.com/Colon-Atlantic-Passenger-Station-Hotels.d6253106.Travel-Guide-Hotels)
- [Hotels near Limon Bay ](https://www.expedia.com/Limon-Bay-Hotels.0-l6035251-0.Travel-Guide-Filter-Hotels)
- [Hotels near Enrique Adolfo Jimenez ](https://www.expedia.com/Enrique-Adolfo-Jimenez-Airport-Hotels.0-aONX-0.Travel-Guide-Filter-Hotels)
- [Beach Hotels in Fort Sherman ](https://www.expedia.com/Fort-Sherman-Hotels-Beach-Hotel.0-0-d6223313-tBeachHotel.Travel-Guide-Filter-Hotels)
- [Fort Sherman Hotels ](https://www.expedia.com/Fort-Sherman-Hotels.d6223313.Travel-Guide-Hotels)
- [Hotels near Galeta Island Marine Education Center ](https://www.expedia.com/Galeta-Island-Marine-Education-Center-Hotels.0-l6253111-0.Travel-Guide-Filter-Hotels)
- [Cativa Hotels ](https://www.expedia.com/Cativa-Hotels.d553248623142874455.Travel-Guide-Hotels)
- [Lodges in Cativa ](https://www.expedia.com/Cativa-Lodges.d553248623142874455-aaLodges.Travel-Guide-Accommodation)
- [Hotels near Gatun Locks ](https://www.expedia.com/Gatun-Locks-Hotels.0-l6078509-0.Travel-Guide-Filter-Hotels)
- [Hotels near Canal Expansion Observation Center ](https://www.expedia.com/Canal-Expansion-Observation-Center-Hotels.0-l553248621532964855-0.Travel-Guide-Filter-Hotels)
- [3 Star Hotels in Sabanitas ](https://www.expedia.com/3Star-Sabanitas-Hotels.s30-0-d3000437347.Travel-Guide-Filter-Hotels)

- [Flights from Enrique Adolfo Jimenez ](https://www.expedia.com/lp/airports/onx/flights-from-enrique-adolfo-jimenez-airport)
- [Flights from Panama City (PTY) to Colon (ONX) ](https://www.expedia.com/lp/flights/pty/onx/panama-city-to-colon)
- [Flights from Miami (MIA) to Colon (ONX) ](https://www.expedia.com/lp/flights/mia/onx/miami-to-colon)
- [Flights from San José (SJO) to Colon (ONX) ](https://www.expedia.com/lp/flights/sjo/onx/san-jose-to-colon)
- [Flights from Los Angeles (LAX) to Colon (ONX) ](https://www.expedia.com/lp/flights/lax/onx/los-angeles-to-colon)
- [Flights from New York (JFK) to Colon (ONX) ](https://www.expedia.com/lp/flights/jfk/onx/new-york-to-colon)
- [Flights from Manila (MNL) to Colon (ONX) ](https://www.expedia.com/lp/flights/mnl/onx/manila-to-colon)
- [Flights from Houston (IAH) to Colon (ONX) ](https://www.expedia.com/lp/flights/iah/onx/houston-to-colon)
- [Flights from Chicago (ORD) to Colon (ONX) ](https://www.expedia.com/lp/flights/ord/onx/chicago-to-colon)
- [Flights from San Francisco (SFO) to Colon (ONX) ](https://www.expedia.com/lp/flights/sfo/onx/san-francisco-to-colon)
- [Flights to Enrique Adolfo Jimenez ](https://www.expedia.com/Cheap-Flights-To-Enrique-Adolfo-Jimenez.d3000676041.Travel-Guide-Flights)
- [Flights from Denver (DEN) to Colon (ONX) ](https://www.expedia.com/lp/flights/den/onx/denver-to-colon)
- [Flights from Dallas (DFW) to Colon (ONX) ](https://www.expedia.com/lp/flights/dfw/onx/dallas-to-colon)
- [Flights from Atlanta (ATL) to Colon (ONX) ](https://www.expedia.com/lp/flights/atl/onx/atlanta-to-colon)
- [Flights from Tampa (TPA) to Colon (ONX) ](https://www.expedia.com/lp/flights/tpa/onx/tampa-to-colon)
- [Flights from Seattle (SEA) to Colon (ONX) ](https://www.expedia.com/lp/flights/sea/onx/seattle-to-colon)
- [Flights from Fort Lauderdale (FLL) to Colon (ONX) ](https://www.expedia.com/lp/flights/fll/onx/fort-lauderdale-to-colon)
- [Flights from Boston (BOS) to Colon (ONX) ](https://www.expedia.com/lp/flights/bos/onx/boston-to-colon)
- [Flights from Las Vegas (LAS) to Colon (ONX) ](https://www.expedia.com/lp/flights/las/onx/las-vegas-to-colon)
- [Flights from Philadelphia (PHL) to Colon (ONX) ](https://www.expedia.com/lp/flights/phl/onx/philadelphia-to-colon)
- [Flights from Phoenix (PHX) to Colon (ONX) ](https://www.expedia.com/lp/flights/phx/onx/phoenix-to-colon)
- [Flights from Washington (IAD) to Colon (ONX) ](https://www.expedia.com/lp/flights/iad/onx/washington-to-colon)
- [Flights from Baltimore (BWI) to Colon (ONX) ](https://www.expedia.com/lp/flights/bwi/onx/baltimore-to-colon)
- [Flights from Port of Spain (POS) to Colon (ONX) ](https://www.expedia.com/lp/flights/pos/onx/port-of-spain-to-colon)
- [Flights from Minneapolis (MSP) to Colon (ONX) ](https://www.expedia.com/lp/flights/msp/onx/minneapolis-to-colon)
- [Flights from Mexico City (MEX) to Colon (ONX) ](https://www.expedia.com/lp/flights/mex/onx/mexico-city-to-colon)
- [Flights from Cartagena (CTG) to Colon (ONX) ](https://www.expedia.com/lp/flights/ctg/onx/cartagena-to-colon)
- [Flights from Balboa (BLB) to Colon (ONX) ](https://www.expedia.com/lp/flights/blb/onx/balboa-to-colon)
- [Flights from Tel Aviv (TLV) to Colon (ONX) ](https://www.expedia.com/lp/flights/tlv/onx/tel-aviv-to-colon)
- [Flights from Bocas del Toro (BOC) to Colon (ONX) ](https://www.expedia.com/lp/flights/boc/onx/bocas-del-toro-to-colon)
- [Flights from Hartford (BDL) to Colon (ONX) ](https://www.expedia.com/lp/flights/bdl/onx/hartford-to-colon)
- [Flights from Lima (LIM) to Colon (ONX) ](https://www.expedia.com/lp/flights/lim/onx/lima-to-colon)
- [Flights from San Juan (SJU) to Colon (ONX) ](https://www.expedia.com/lp/flights/sju/onx/san-juan-to-colon)
- [Flights from Oranjestad (AUA) to Colon (ONX) ](https://www.expedia.com/lp/flights/aua/onx/oranjestad-to-colon)
- [Flights from Cancun (CUN) to Colon (ONX) ](https://www.expedia.com/lp/flights/cun/onx/cancun-to-colon)
- [Flights from Bogotá (BOG) to Colon (ONX) ](https://www.expedia.com/lp/flights/bog/onx/bogota-to-colon)
- [Flights from Winnipeg (YWG) to Colon (ONX) ](https://www.expedia.com/lp/flights/ywg/onx/winnipeg-to-colon)
- [Flights from Panama City (PAC) to Colon (ONX) ](https://www.expedia.com/lp/flights/pac/onx/panama-city-to-colon)
- [Flights from Salt Lake City (SLC) to Colon (ONX) ](https://www.expedia.com/lp/flights/slc/onx/salt-lake-city-to-colon)
- [Flights from Quito (UIO) to Colon (ONX) ](https://www.expedia.com/lp/flights/uio/onx/quito-to-colon)
- [Flights from Mumbai (BOM) to Colon (ONX) ](https://www.expedia.com/lp/flights/bom/onx/mumbai-to-colon)
- [Flights from Geneva (GVA) to Colon (ONX) ](https://www.expedia.com/lp/flights/gva/onx/geneva-to-colon)
- [Flights from Knoxville (TYS) to Colon (ONX) ](https://www.expedia.com/lp/flights/tys/onx/knoxville-to-colon)
- [Flights from Munich (MUC) to Colon (ONX) ](https://www.expedia.com/lp/flights/muc/onx/munich-to-colon)
- [Flights from Providence (PVD) to Colon (ONX) ](https://www.expedia.com/lp/flights/pvd/onx/providence-to-colon)
- [Flights from Frankfurt (FRA) to Colon (ONX) ](https://www.expedia.com/lp/flights/fra/onx/frankfurt-to-colon)
- [Flights from London (LON) to Colon (ONX) ](https://www.expedia.com/lp/flights/lon/onx/london-to-colon)
- [Flights from San Salvador (SAL) to Colon (ONX) ](https://www.expedia.com/lp/flights/sal/onx/san-salvador-to-colon)
- [Flights from Guatemala City (GUA) to Colon (ONX) ](https://www.expedia.com/lp/flights/gua/onx/guatemala-city-to-colon)
- [Flights from Punta Cana (PUJ) to Colon (ONX) ](https://www.expedia.com/lp/flights/puj/onx/punta-cana-to-colon)
- [Flights from Toronto (YYZ) to Colon (ONX) ](https://www.expedia.com/lp/flights/yyz/onx/toronto-to-colon)
- [Flights from Buenos Aires (AEP) to Colon (ONX) ](https://www.expedia.com/lp/flights/aep/onx/buenos-aires-to-colon)
- [Flights from Buenos Aires (EZE) to Colon (ONX) ](https://www.expedia.com/lp/flights/eze/onx/buenos-aires-to-colon)
- [Flights from New York (NYC) to Colon (ONX) ](https://www.expedia.com/lp/flights/nyc/onx/new-york-to-colon)
- [Flights from George Town (GCM) to Colon (ONX) ](https://www.expedia.com/lp/flights/gcm/onx/george-town-to-colon)
- [Flights from Copenhagen (CPH) to Colon (ONX) ](https://www.expedia.com/lp/flights/cph/onx/copenhagen-to-colon)
- [Flights from Madrid (MAD) to Colon (ONX) ](https://www.expedia.com/lp/flights/mad/onx/madrid-to-colon)
- [Flights from Düsseldorf (DUS) to Colon (ONX) ](https://www.expedia.com/lp/flights/dus/onx/dusseldorf-to-colon)
- [Flights from Brussels (BRU) to Colon (ONX) ](https://www.expedia.com/lp/flights/bru/onx/brussels-to-colon)
- [Flights from Guayaquil (GYE) to Colon (ONX) ](https://www.expedia.com/lp/flights/gye/onx/guayaquil-to-colon)
- [Flights from Barcelona (BCN) to Colon (ONX) ](https://www.expedia.com/lp/flights/bcn/onx/barcelona-to-colon)
- [Flights from Warsaw (WAW) to Colon (ONX) ](https://www.expedia.com/lp/flights/waw/onx/warsaw-to-colon)
- [Flights from Vitoria (VIX) to Colon (ONX) ](https://www.expedia.com/lp/flights/vix/onx/vitoria-to-colon)
- [Flights from Oslo (OSL) to Colon (ONX) ](https://www.expedia.com/lp/flights/osl/onx/oslo-to-colon)
- [Flights from Guadalajara (GDL) to Colon (ONX) ](https://www.expedia.com/lp/flights/gdl/onx/guadalajara-to-colon)
- [Flights from Istanbul (IST) to Colon (ONX) ](https://www.expedia.com/lp/flights/ist/onx/istanbul-to-colon)
- [Flights from Manchester (MAN) to Colon (ONX) ](https://www.expedia.com/lp/flights/man/onx/manchester-to-colon)
- [Flights from Sarasota (SRQ) to Colon (ONX) ](https://www.expedia.com/lp/flights/srq/onx/sarasota-to-colon)
- [Flights from Monterrey (MTY) to Colon (ONX) ](https://www.expedia.com/lp/flights/mty/onx/monterrey-to-colon)
- [Flights from Stockholm (ARN) to Colon (ONX) ](https://www.expedia.com/lp/flights/arn/onx/stockholm-to-colon)
- [Flights from Fort Sherman ](https://www.expedia.com/lp/flights/6223313/flights-from-fort-sherman)
- [Flights to Cativa ](https://www.expedia.com/Cheap-Flights-To-Cativa.d553248623142874455.Travel-Guide-Flights)

- [Monument to Christopher Columbus ](https://www.expedia.com/Monument-To-Christopher-Columbus-Barrio-Norte.d6286215.Vacation-Attraction)
- [Colon 2000 ](https://www.expedia.com/Colon-2000-Barrio-Sur.d6286212.Vacation-Attraction)
- [Juventud Park ](https://www.expedia.com/Juventud-Park-Barrio-Norte.d653900748409483264.Vacation-Attraction)
- [Colon Free Zone ](https://www.expedia.com/Colon-Free-Zone-Barrio-Sur.d6078503.Vacation-Attraction)
- [Limon Bay ](https://www.expedia.com/Limon-Bay-Colon.d6035251.Vacation-Attraction)
- [Visit Fort Sherman ](https://www.expedia.com/Fort-Sherman.dx6223313)
- [Fort Sherman Vacations ](https://www.expedia.com/Fort-Sherman.d6223313.Destination-Travel-Guides)
- [Galeta Island Marine Education Center ](https://www.expedia.com/Galeta-Island-Marine-Education-Center-Colon.d6253111.Vacation-Attraction)
- [Visit Cativa ](https://www.expedia.com/Cativa.dx553248623142874455)
- [Cativa Vacations ](https://www.expedia.com/Cativa.d553248623142874455.Destination-Travel-Guides)
- [Gatun Locks ](https://www.expedia.com/Gatun-Locks-Colon.d6078509.Vacation-Attraction)
- [Visit Gatun ](https://www.expedia.com/Colon-Gatun.dx6025905)
- [Canal Expansion Observation Center ](https://www.expedia.com/Canal-Expansion-Observation-Center-Colon.d553248621532964855.Vacation-Attraction)
- [Visit Sabanitas ](https://www.expedia.com/Sabanitas.dx3000437347)

- [Car rentals near Colon 2000 ](https://www.expedia.com/Car-Rentals-In-Colon-2000.d6286212.Car-Rental-Guide)
- [Car rentals near Colon Free Zone ](https://www.expedia.com/Car-Rentals-In-Colon-Free-Zone.d6078503.Car-Rental-Guide)