Are there any 5-star vacation rentals in Colon?

Although you won't find any 5-star vacation rentals in Colon on our site, we have a range of stays that promise an awesome getaway. Discover one that suits your needs by checking out our vacation rentals in Colon .

The Best 5 Star Hotels in Colon from $93

A historic stone fortress with a central dome and surrounding walls.

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Our top choices for Colon 5-star hotels

A rooftop pool with sun loungers and umbrellas, surrounded by palm trees and modern buildings.

1. Hotel Riu Plaza Panama

Bella Vista

Rafael

$132 nightly

Dec 1 - Dec 2

Total with taxes and fees

A modern building with a rooftop lounge area, large windows, and a balcony overlooking a cityscape.

2. Waldorf Astoria Panama

Bella Vista

Oscar

$277 nightly

Nov 7 - Nov 8

Total with taxes and fees

A pool area with lounge chairs and umbrellas, surrounded by greenery and a multi-story building in the background.

3. Hyatt Regency Panama City

Bella Vista

Mariah

$240 nightly

Dec 4 - Dec 5

Total with taxes and fees

A poolside area with lounge chairs and a view of the ocean.

4. JW Marriott Panama

San Francisco

GIORIA

$335 nightly

Nov 27 - Nov 28

Total with taxes and fees

A large bed with a wooden headboard, two bedside tables with lamps, and a view of a balcony with curtains.

5. Sofitel Legend Casco Viejo, Panama City

Casco Viejo

Ricardo E

$477 nightly

Nov 29 - Nov 30

Total with taxes and fees

A hotel entrance with a central water feature, seating areas, and potted plants.

6. The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City

Juan Diaz

Carmen

$314 nightly

Nov 27 - Nov 28

Total with taxes and fees

A high-rise building with a rooftop pool area, surrounded by other buildings.

7. W Panama

Bella Vista

Jerome

$258 nightly

Nov 22 - Nov 23

Total with taxes and fees

A modern hotel room with a sofa, a coffee table, a TV mounted on the wall, and a dining area with a table and chairs.

8. Renaissance Panama City Hotel

Bella Vista

Carlos

$127 nightly

Nov 15 - Nov 16

Total with taxes and fees

A hotel courtyard with a central lawn, surrounded by buildings with balconies and outdoor seating areas.

9. Hotel La Compañía Casco Antiguo

Casco Viejo

Carlos A

$327 nightly

Dec 1 - Dec 2

Total with taxes and fees

A modern living room with a sofa, round black ottomans, and a vase of flowers. A cityscape is visible through the window.

10. Bristol Panama, a Registry Collection Hotel

Bella Vista

Juliet

$212 nightly

Nov 13 - Nov 14

Total with taxes and fees

A modern hotel pool area with lounge chairs and a clear view of the ocean.

11. Hilton Panama

Bella Vista

Simon

$229 nightly

Nov 6 - Nov 7

Total with taxes and fees

A hotel with a pool, beach, and palm trees.

12. The Westin Playa Bonita Panama

Veracruz

Phillip James

$215 nightly

Nov 15 - Nov 16

Total with taxes and fees

13. Waymore Hotel Spa and Casino

Bella Vista

Mathe

$94 nightly

Nov 17 - Nov 18

Total with taxes and fees

14. Megapolis Hotel Panamá

San Francisco

MARVIN

$245 nightly

Nov 26 - Nov 27

Total with taxes and fees

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Explore similar 4-star hotels

Many 4-star hotels have the same amenities as 5-star hotels. See all 4-star hotels in Colon.

Hotel El Panama by Faranda Grand, a member of Radisson Individuals

Via Espana 111 Panama City Panama

$85 nightly

$93 total

Nov 17 - Nov 18

Total with taxes and fees

7.8/10 Good! (1,008 reviews)

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Pool Spa Hot tub Breakfast included Waterpark

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Learn more about Colon

Explore the colorful Zona Libre free trade zone for duty-free shopping and visit the historic Colon 2000 cruise port. Discover Panama's colonial history at Fort San Lorenzo, located on the Caribbean coast outside the city.

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Top Colon Hotel Reviews

Find out more about Colon

There's nothing wrong with enjoying the finer things in life. Add an extra layer of luxury on your next trip to Colon by treating yourself to the best of the best when it comes to lodging. It's an ideal pairing. There's no reason to delay a getaway to Colon any longer. You'll join the multitudes of vacationers who have made Colon so fashionable recently. You can also expect excellent customer service from these hotels, so get ready to kick back and indulge. Don't wait any longer. Book one of Expedia's luxurious 5-star hotels in Colon and get ready to be pampered like never before.

Book the Best Colon 5-Star Hotels

You'll have a wonderful time at one of these 5-star hotels. High-end restaurants, concierges, and pillow-fluffing are all at the ready. You're sure to find exactly the accommodation you need. You can also look forward to an outstanding experience and fantastic customer care, so get ready to kick back and indulge. How do you want to relax? A rejuvenating facial treatment to help your cares fall away? A concierge to help you suggest the next attraction to visit? Fluffy down pillows, lip-smacking main courses, and even space for your family pet in some cases...these hotels are one-of-a-kind. Don't want to take our word for it? Explore our listings and pick the perfect accommodation for your needs.

You won't sleep and order room service the entire time, though. We hear you. From doing a bit of shopping to embracing the great outdoors, you'll never be bored on this retreat. Whatever you plan to do, the 5-star hotels in Colon are waiting for you to rest up after a busy day.

Make Your Escape

The results are in, and Colon 5-star hotels are the place to be when you book your next vacation. If you've been dreaming about a vacation set here, then go ahead and book it. Expedia can help you land a great deal on accommodation. Don't put off your dream vacation any longer. Choose one of our Colon 5-star hotels today and relax in total tranquility tomorrow.

Frequently asked questions

How much does it cost to stay in a 5-star hotel in Colon?

The amount you pay for a 5-star hotel in Colon depends on factors such as when you want to go and the length of your getaway. Our top tip for bagging the best deal? Use our pricing filters to compare the available accommodations for your chosen dates.

Search for the lowest price per night from $93

What makes a hotel 5 stars in Colon?

In Colon, a hotel needs to offer a specific level of upscale features to earn a 5-star rating. These may include on-site gyms, gourmet restaurants, saunas and spas, premium bedding, luxury bathroom products and more. What also sets 5-star hotels apart is their superior service. You can look forward to things like in-room massages, concierge services and nightly turn-down services. Some may also offer extra touches such as welcome gifts.

Are there any 5-star all-inclusive resorts in Colon?

Find a luxury escape that includes your lodging, food, activities and entertainment in Colon with the help of our filter tool. Search for resorts rated 5 stars and click on the "All inclusive" filter. Have a look at what's included in the price. This way, you can take full advantage of the many perks on offer from the moment you get there.

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Things to do in Colon

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