Commerce, MO

Travel Guide

Drury Plaza Hotel Cape Girardeau Conference Center

Drury Plaza Hotel Cape Girardeau Conference Center

3 out of 5
3351 Percy Drive Cape Girardeau MO
$100 nightly
The price is $113 total per night from May 31 to Jun 1
$113 total
May 31 - Jun 1
Total with taxes and fees
Book a stay at this business-friendly hotel in Cape Girardeau. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
9.6/10 Exceptional! (1,006 reviews)
"Great place to stay as a family"

Reviewed on May 25, 2026

Drury Plaza Hotel Cape Girardeau Conference Center
Drury Inn & Suites Sikeston, MO

Drury Inn & Suites Sikeston, MO

3 out of 5
2608 East Malone Ave, Miner Sikeston MO
Fully refundableReserve now, pay when you stay
$111 nightly
The price is $128 total per night from May 30 to May 31
$128 total
May 30 - May 31
Total with taxes and fees
Book a stay at this business-friendly hotel in Sikeston. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
9.6/10 Exceptional! (1,005 reviews)
"Very nice clean room. Staff was very nice."

Reviewed on May 24, 2026

Drury Inn & Suites Sikeston, MO
The Riverview

The Riverview

4 out of 5
777 Main St Cape Girardeau MO
$120 nightly
The price is $135 total per night from May 27 to May 28
$135 total
May 27 - May 28
Total with taxes and fees
Book a stay at this business-friendly hotel in Cape Girardeau. Enjoy free WiFi, free parking, and 2 restaurants. Popular attractions Century Casino & Hotel Cape ...
9.4/10 Exceptional! (581 reviews)
"Front desk staff was not welcoming at all, was extremely rude to myself and my children. The room itself was nice, however due to the rude staff we will not stay here again."

Reviewed on May 25, 2026

The Riverview
See all 84 properties in Commerce
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Peaceful secluded cabin located near Horseshoe Lake

Peaceful secluded cabin located near Horseshoe Lake

Miller City IL
Stay at this cabin in Alexander County. Enjoy an in-room coffeemaker and air conditioning.
Peaceful secluded cabin located near Horseshoe Lake
“Kozy on Kingsway” is a charming 4-bedroom house in Cape -The City of Roses

“Kozy on Kingsway” is a charming 4-bedroom house in Cape -The City of Roses

Cape Girardeau MO
Stay at this vacation home in Cape Girardeau. Enjoy laundry facilities and air conditioning. Popular attractions Cape Splash Family Aquatic Center and Show Me ...
9.6/10 Exceptional! (4 reviews)
"The house is 4 bedroom/2 bath/but one bedroom is in the basement and both bathrooms are upstairs. I don't think the listing explains that. The house was immaculately clean! Probably the cleanest rental I've ever seen. The location was great! Very close to everything but in a neighborhood that is ..."

Reviewed on May 20, 2026

“Kozy on Kingsway” is a charming 4-bedroom house in Cape -The City of Roses
Serenity South -- Gardens, River-Views, and Refreshing Space

Serenity South -- Gardens, River-Views, and Refreshing Space

Cape Girardeau MO
Stay at this vacation home in Cape Girardeau. Enjoy a garden, patios, and an in-room coffeemaker. Popular attractions eDen Spa & Salon and The Glenn House are ...
10/10 Exceptional! (156 reviews)
"A true gem! The perfect location! Walking distance to all of downtown’s offerings! All guests were very comfortable and there were plenty of toiletries, towels, and kitchen essentials. The most comfortable bed I’ve had in a rental! Plenty of pillows too!"

Reviewed on May 25, 2026

Serenity South -- Gardens, River-Views, and Refreshing Space
See all properties in Commerce
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.