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De Soto Vacation Rentals

Check prices for these dates

In two weeks
Oct 9 - Oct 11
In two months
Nov 20 - Nov 22
In three months
Dec 18 - Dec 20
In four months
Jan 15 - Jan 17

Our top choices for De Soto vacation rentals

A swimming pool surrounded by a white picket fence, with a gazebo and outdoor seating area.

1. Experience Glamping in style. private Hot tub spa! Private lake -Pet Friendly

Experience Glamping in style. private Hot tub spa! Private lake -Pet Friendly
De Soto
10.0 out of 10, Exceptional, (32 reviews)
"Wonderful place, lots of amenities"
United States
Julia M.
$153 nightly
The price is $169
Sep 24 - Sep 25
Total with taxes and fees
Experience Glamping in style. private Hot tub spa! Private lake -Pet Friendly
A swimming pool surrounded by a white picket fence, with a gazebo and outdoor seating area.

2. Experience Glamping in style. Private Lake - Pet Friendly!

Experience Glamping in style. Private Lake - Pet Friendly!
De Soto
9.8 out of 10, Exceptional, (54 reviews)
"Extremely pet and family friendly, we loved our visit!"
United States
Lindsey T.
$134 nightly
The price is $148
Sep 23 - Sep 24
Total with taxes and fees
Experience Glamping in style. Private Lake - Pet Friendly!
A compact kitchen with wooden walls, a built-in oven, a sink, and a refrigerator.

3. The Cozy Corner

The Cozy Corner
De Soto
10.0 out of 10, Exceptional, (1 review)
"Nice, small, cozy place to stay in! Really worked well with two people! The appliances were up to date and easy to use. The property is within around 20 minutes of multiple towns, so it's super easy to travel around! Highly recommend and I would stay here again!"
United States
Ryn J.
$131 nightly
The price is $145
Oct 1 - Oct 2
Total with taxes and fees
The Cozy Corner
A cozy cabin interior with a stone fireplace, wooden walls, and various framed pictures.

4. Pine Cabin #3 on 30 Acres! 1 mi. from Carbondale, IL & SIUC Campus

Pine Cabin #3 on 30 Acres! 1 mi. from Carbondale, IL & SIUC Campus
Carbondale
9.2 out of 10, Wonderful, (154 reviews)
"Great place to get away while still being close enough to town"
United States
Travis S.
$143 nightly
The price is $151
Sep 24 - Sep 25
Total with taxes and fees
Pine Cabin #3 on 30 Acres! 1 mi. from Carbondale, IL & SIUC Campus
A spacious living area with a brick wall, hanging chairs, a white sofa, and a coffee table.

5. Third-Floor Suite, SIU Across Street

Third-Floor Suite, SIU Across Street
Carbondale
10.0 out of 10, Exceptional, (35 reviews)
"Everything has good. Would stay here again."
United States
Kathy A.
$130 nightly
The price is $155
Sep 23 - Sep 24
Total with taxes and fees
Third-Floor Suite, SIU Across Street
A modern living room with a sectional sofa, a coffee table, a TV mounted on the wall, and a window with blinds.

6. The Lab! Come stay in our brand new space.

The Lab! Come stay in our brand new space.
Murphysboro
9.6 out of 10, Exceptional, (31 reviews)
"Exactly as advertised with comfy beds and modern appliances. Easy one block walk to the shops downtown and there’s an awesome Big Muddy Monster mural by the parking lot for a memorable picture."
United States
Branda K.
$194 nightly
The price is $205
Sep 26 - Sep 27
Total with taxes and fees
The Lab! Come stay in our brand new space.
A compact kitchen with wooden cabinets, a microwave, a trash bin, and a dining table with placemats.

7. Pet Friendly! Couples Retreat in Southern Illinois

Pet Friendly! Couples Retreat in Southern Illinois
3.0 star property
Murphysboro
$212 nightly
The price is $235
Sep 23 - Sep 24
Total with taxes and fees
Pet Friendly! Couples Retreat in Southern Illinois
A wooden deck with a table and chairs, leading to a building with a window and a wall-mounted light fixture.

8. Minutes to Giant City - SIU - Shawnee Winetrail - Shawnee Forest - Wi-Fi

Minutes to Giant City - SIU - Shawnee Winetrail - Shawnee Forest - Wi-Fi
Makanda
9.4 out of 10, Exceptional, (52 reviews)
"Great place to stay and host was wonderful! Definitely would stay again in the future."
United States
Teal B.
$165 nightly
The price is $182
Sep 23 - Sep 24
Total with taxes and fees
Minutes to Giant City - SIU - Shawnee Winetrail - Shawnee Forest - Wi-Fi
A stationary RV with a covered top, a sliding door, and a small window.

9. Lois' Hideout Comfy 1 bedroom camper within 7 minutes of Kinkaid Lake.

Lois' Hideout Comfy 1 bedroom camper within 7 minutes of Kinkaid Lake.
Oraville
10.0 out of 10, Exceptional, (2 reviews)
"Great place great communication"
United States
Kevin E.
$103 nightly
The price is $109
Sep 23 - Sep 24
Total with taxes and fees
Lois' Hideout Comfy 1 bedroom camper within 7 minutes of Kinkaid Lake.
A campfire with logs and branches, surrounded by a grassy area with trees and a house in the background.

10. The Lux Collective- Private Hot Tub, Dry Bar, 1-Acre Yard & Fire Pit

The Lux Collective- Private Hot Tub, Dry Bar, 1-Acre Yard & Fire Pit
Murphysboro
$232 nightly
The price is $245
Sep 29 - Sep 30
Total with taxes and fees
The Lux Collective- Private Hot Tub, Dry Bar, 1-Acre Yard & Fire Pit
A wooden cabin with a front porch, a staircase, and a door.

11. Pet Friendly! Countryside Couples Stay in Illinois

Pet Friendly! Countryside Couples Stay in Illinois
Murphysboro
8.0 out of 10, Very good, (3 reviews)
"We really enjoyed our stay overall. The location was excellent—quiet, peaceful, and set far enough away from town to avoid traffic, but still close enough to get anywhere quickly. The outdoor space was a big plus, especially for our dogs, who had plenty of room to roam. The beds were also very comfortable, which made for a great night’s sleep. The only downside was the cleanliness. The property was noticeably dusty, and the inside of the refrigerator could have been cleaned more thoroughly. With...
United States
Jim P.
$213 nightly
The price is $236
Sep 23 - Sep 24
Total with taxes and fees
Pet Friendly! Countryside Couples Stay in Illinois

12. Fantastic 1-bedroom Cabin in peaceful Makanda, Pet-Friendly!

Fantastic 1-bedroom Cabin in peaceful Makanda, Pet-Friendly!
Makanda
10.0 out of 10, Exceptional, (27 reviews)
"Great place to stay, close to a lot of good attractions and has many provided amenities for an optimal stay. Pretty location, quiet, and privacy is great."
United States
Ammon H.
$141 nightly
The price is $149
Oct 4 - Oct 5
Total with taxes and fees
Fantastic 1-bedroom Cabin in peaceful Makanda, Pet-Friendly!
A deck with a fire pit surrounded by rocks, two chairs, and a view of a forested area.

13. Pine Cabin #2 on 30 Acres! 1 mi. from Carbondale, IL & SIUC Campus

Pine Cabin #2 on 30 Acres! 1 mi. from Carbondale, IL & SIUC Campus
Carbondale
8.8 out of 10, Excellent, (81 reviews)
"Kind host and great location"
United States
Rocco C.
$212 nightly
The price is $224
Sep 25 - Sep 26
Total with taxes and fees
Pine Cabin #2 on 30 Acres! 1 mi. from Carbondale, IL & SIUC Campus

14. Cabin 2: Lakeside in Murphysboro

Cabin 2: Lakeside in Murphysboro
Murphysboro
8.0 out of 10, Very good, (3 reviews)
"Perfect but beware if you are a sensitive sleeper as the mattress on the queen bed is saggy and in need of replacing. Probably fine for 1 person but 2 people easily roll into the middle making for a not-so-good night's sleep."
United States
Pamela S.
$221 nightly
The price is $244
Sep 27 - Sep 28
Total with taxes and fees
Cabin 2: Lakeside in Murphysboro
A swimming pool surrounded by a white picket fence, with a gazebo and outdoor seating area.

15. Experience Glamping in style. Private Hot tub spa! Private lake -Pet Friendly

Experience Glamping in style. Private Hot tub spa! Private lake -Pet Friendly
De Soto
9.6 out of 10, Exceptional, (52 reviews)
"Everything was excellent. What a nice place to stay and relax. "
United States
Thomas P.
$156 nightly
The price is $173
Sep 23 - Sep 24
Total with taxes and fees
Experience Glamping in style. Private Hot tub spa! Private lake -Pet Friendly
A small house with a covered patio, string lights, and a sliding glass door.

16. Charming 3 bedroom retreat

Charming 3 bedroom retreat
Herrin
10.0 out of 10, Exceptional, (3 reviews)
"We stayed here while visiting family in the area. Clean and well maintained property to relax in after a long day of fun with the family. The property manager is amazing and very helpful. I definitely recommend staying here and we will be back."
United States
Ronald H.
$254 nightly
The price is $282
Sep 23 - Sep 24
Total with taxes and fees
Charming 3 bedroom retreat
A wooden cabin with a front porch, a staircase, and a door.

17. Pet Friendly! Countryside Couples Stay in Illinois

Pet Friendly! Countryside Couples Stay in Illinois
2.5 star property
Murphysboro
$218 nightly
The price is $242
Sep 23 - Sep 24
Total with taxes and fees
Pet Friendly! Countryside Couples Stay in Illinois
A log cabin with a hot tub, a sofa, and a table with a lamp.

18. Screened Hot Tub & Peacocks Nearby

Screened Hot Tub & Peacocks Nearby
Carbondale
10.0 out of 10, Exceptional, (116 reviews)
"Great property"
United States
Brandon D.
$238 nightly
The price is $263
Sep 23 - Sep 24
Total with taxes and fees
Screened Hot Tub & Peacocks Nearby
A wooden cabin with a green door, a number '2' sign, a small porch with a wooden railing, and a wall-mounted lantern.

19. 3 Minutes to Giant City - 6 Minutes to SIU - 4 Minutes to Shawnee Winetrail!

3 Minutes to Giant City - 6 Minutes to SIU - 4 Minutes to Shawnee Winetrail!
Makanda
9.8 out of 10, Exceptional, (75 reviews)
"Very clean and comfortable stay"
United States
Alison K.
$165 nightly
The price is $182
Sep 28 - Sep 29
Total with taxes and fees
3 Minutes to Giant City - 6 Minutes to SIU - 4 Minutes to Shawnee Winetrail!
A compact RV kitchen with wooden cabinets, a microwave, a stove, and a sink.

20. Kinkaid Kamper with AC in Oraville - 2 bedrooms for a cozy stay. house mattress

Kinkaid Kamper with AC in Oraville - 2 bedrooms for a cozy stay. house mattress
Oraville
9.4 out of 10, Exceptional, (3 reviews)
"Had a nice time. Loved staying in the camper. The host was very prompt when communicating. Would definitely stay again."
United States
Joseph S.
$174 nightly
The price is $184
Sep 23 - Sep 24
Total with taxes and fees
Kinkaid Kamper with AC in Oraville - 2 bedrooms for a cozy stay. house mattress
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top De Soto Hotel Reviews

Baymont by Wyndham Marion

Baymont by Wyndham Marion

8/10 Good
"although not new the hotel was in good condition and the price was acceptable"
Marcus 1-night trip
Posted 9 hours ago
Baymont by Wyndham Marion

Find out more about De Soto

Everything you need to know about De Soto vacation rentals

Whether you’re excited for the perfect family vacation, a romantic getaway for two, or the ultimate city break, we’ve got the De Soto vacation rental for you. At Expedia, you can take your pick from private vacation homes, apartments, condos, resorts, cabins, villas, motels. The list goes on, and on …and on.

There’s just as wide a choice of amenities, too. Maybe you’re dreaming of your own pool, long evenings in a hot tub, or watching the kids laugh through the day at a waterpark. Maybe you just want a quiet retreat in a pet-friendly apartment. Well, we can help you find it. Hunt out the perfect De Soto vacation rental for you by simply entering your desired dates. Then check your favorite filters to narrow down your search.

De Soto vacation rentals: An excellent choice for every season

Whenever you want to travel, a warm welcome awaits you in De Soto. If you’re looking for a little peace, consider booking during the quieter low season months. For more hustle and bustle, you may prefer to visit De Soto in high season.

Prices vary throughout the year. Your chosen location, property type, and amenities will impact the cost of your trip, too. The selection of properties we have chosen for you start as low as $128 per night. Rates vary depending on your travel dates, location, and amenities so make a search and you might find even better deals!

How to find incredible deals on De Soto rentals

At Expedia, we put the best De Soto vacation rentals in one place. All you need to do is take your pick. And as we offer book now, pay later options, as well as free cancellation on some properties, you can plan your trip with total peace of mind. You’ll always find a great deal with Expedia.

To find some top De Soto rental deals, enter your travel dates, and sort your search results by price. You can also filter by budget, so you only see accommodation in your ballpark. Next, add any filters you want—and just like that, you’ve built your dream De Soto vacation.

If you’re looking for a little inspiration, browse our latest incredible offers, or use the map to view all accommodation in and around De Soto. And to unlock even more fantastic deals, bundle your accommodation, flights, and car rental together to save and book with Expedia in complete confidence.

Frequently asked questions

Can I find a vacation rental in De Soto?

Yes, you can find vacation rentals near well known local attractions in De Soto, or you can choose a secluded option if you're looking for a relaxing stay.

What are some of the best vacation home rentals in De Soto?

* On the Wine Trail * Hot Tub * Wi-Fi *: This vacation home rental outside of De Soto is located on a lake and has a patio, a hot tub, and a barbecue grill to put you at ease in your new surroundings. Kitchen amenities include a fridge, a stovetop, and a microwave.

What can I see and do in De Soto?

While you're exploring the area, De Soto City Park and Little Grand Canyon Trail Trailhead are a couple of picturesque spots to get outside and enjoy nature. Hickory Ridge Public Golf Center and Southern Illinois University are a couple of places you'll find in the larger area.

What are vacation rentals like in De Soto?

Vacation rentals are private accommodations you can stay in for several days or longer in De Soto. Vacation rentals feature amenities such as kitchens and laundry facilities so you'll have everything you need. If you're concerned about cleanliness, vacation rentals can offer a sense of safety away from shared hotel elevators and busy lobbies while still allowing you a great travel experience. You'll also have more space in a vacation rental than in a traditional hotel, which makes a vacation rental a popular option for a family trip.