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Vacation Rentals in Cape Girardeau County

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Top Cities in Cape Girardeau County

Top Vacation Rentals in Cape Girardeau County

Apartment in Cape Girardeau

9.6 out of 10, Exceptional, (44)
"This place is AWESOME! It's clean, artsy, fun, and if we ever have a chance, we will certainly return!"
United States
Jordan S.
$132 nightly
The price is $138
Dec 8 - Dec 9
Total with taxes and fees
Artistic and Creative Vibe with Indoor Swing 2 Blocks to Downtown & near SEMO

Vacation Home in Cape Girardeau

8.6 out of 10, Excellent, (48)
"Some issues with check-in. Very nice area. Lot of history."
United States
Jeffrey M.
$101 nightly
The price is $101
Dec 8 - Dec 9
Total with taxes and fees
Little Blue Cottage on Spanish

Apartment in Jackson

10.0 out of 10, Exceptional, (11)
"Our stay was amazing. Everything was so clean organized, and anything you would possibly need was in the room. We will definitely be staying there again when in the area!!"
United States
Karen P.
$170 nightly
The price is $183
Dec 8 - Dec 9
Total with taxes and fees
Villa B offers peace and quiet with beautiful views of the countryside.

Cabin in Cape Girardeau

10.0 out of 10, Exceptional, (27)
"The place was awesome very clean the host was very accommodating. Nice a quiet for a relaxing stay highly recommend "
United States
Gary C.
$289 nightly
The price is $301
Dec 8 - Dec 9
Total with taxes and fees
The Twisted Sassafras Treehouse

Vacation Home in Cape Girardeau

8.6 out of 10, Excellent, (35)
"Very nice house. The pool and hot tub were perfect for a short getaway. Tons of activities and games to keep the fanily entertained. Will definitely come back! "
United States
Emily D.
$206 nightly
The price is $214
Dec 8 - Dec 9
Total with taxes and fees
3+ acre Home: Pool Table, Putt-Putt, 4 miles to Downtown and SEMO, Summer Pool

Apartment in Jackson

10.0 out of 10, Exceptional, (33)
"Great place to stay, felt like home away from home. "
United States
Brittany
$170 nightly
The price is $183
Dec 8 - Dec 9
Total with taxes and fees
Relax in the country at Countryside Villas! - Villa A

Mobile Home in Jackson

10.0 out of 10, Exceptional, (2)
"This Cottage was very nice and clean and well maintained. The meat tray that we ordered and the breakfast tray was beyond Fabulous!!! My husband is still talking about it. . .Rick & Renee Christman"
United States
Renee C.
$195 nightly
The price is $195
Dec 8 - Dec 9
Total with taxes and fees
The Cottage, Rusted Route Farms

Vacation Home in Cape Girardeau

10.0 out of 10, Exceptional, (148)
"Such a great place and location"
United States
Tracy H.
$229 nightly
The price is $245
Dec 8 - Dec 9
Total with taxes and fees
Serenity South -- Gardens, River-Views, and Refreshing Space

Cabin in Jackson

10.0 out of 10, Exceptional, (3)
"incredible place. I was there for work, but it was a really nice relaxing area to retreat too, and also get some work done in a serene environment. It would be an incredible place for an entire family. And, a good place for friends to get together."
United States
Chandler G.
$310 nightly
The price is $310
Dec 8 - Dec 9
Total with taxes and fees
Gorgeous 1856 Log Cabin, Completely Renovated

Vacation Home in Cape Girardeau

9.6 out of 10, Exceptional, (7)
"Nice place, great times"
United States
Jace W.
$422 nightly
The price is $438
Dec 8 - Dec 9
Total with taxes and fees
4-Bedroom Home - 2 King Beds, Summer Pool, Pool Table, Air Hockey + More

Aparthotel in Perryville

3.0 star property
9.2 out of 10, Wonderful, (17)
"Great place to stay! "
United States
Eric
$208 nightly
The price is $238
Dec 31 - Jan 1, 2026
Total with taxes and fees
Urban Lofts

Vacation Home in Pomona

10.0 out of 10, Exceptional, (60)
"It was very nice and clean. We really enjoyed staying there. We would love to rent this place again. "
United States
susan B.
$141 nightly
The price is $150
Dec 8 - Dec 9
Total with taxes and fees
Beautiful location in the secluded woods

Apartment in Marble Hill

7.0 out of 10, Good, (4)
"Host was not properly notified of the booking, but made the accommodations made several trips to make sure we were checked in and comfortable. Also gave very good advice for local points of interest."
United States
Chrystine H.
$127 nightly
The price is $133
Dec 9 - Dec 10
Total with taxes and fees
Charming 2-bedroom apartment in fabulous Marble Hill with AC

Cabin in Olive Branch

9.8 out of 10, Exceptional, (35)
"Beautiful place, host was kind and and quick to respond to messages "
United States
Melissa W.
$133 nightly
The price is $140
Dec 8 - Dec 9
Total with taxes and fees
Cozy cabins on beautiful Horseshoe Lake

Cabin in Dongola

10.0 out of 10, Exceptional, (101)
"Location was great, everything was great for what we were there for. Already booked again for November. "
United States
carlton h.
$265 nightly
The price is $281
Dec 8 - Dec 9
Total with taxes and fees
Charming cottage overlooking Lake Acre

Cabin in Miller City

9.8 out of 10, Exceptional, (20)
"cute A frame in a secluded spot. Couldn’t ask for a more relaxing situation. "
United States
Jason M.
Peaceful secluded cabin located near Horseshoe Lake

Cabin in Olive Branch

9.2 out of 10, Wonderful, (25)
"This is an excellent place to stay. With a nice lake right across the street. If i. In the are i will stay again for sure"
United States
mike b.
$133 nightly
The price is $140
Dec 8 - Dec 9
Total with taxes and fees
The Rested Duck Mallard Room

Cabin in Anna

10.0 out of 10, Exceptional, (403)
"Very clean, courteus staff. Beautiful area and quiet. Very relaxing."
United States
Tommy
$189 nightly
The price is $200
Dec 8 - Dec 9
Total with taxes and fees
Rest, Relax and Renew. Our log cabin experience awaits your arrival.

Cabin in Makanda

9.6 out of 10, Exceptional, (39)
"The cabin was perfect for our 5 nights in the area. There was plenty of room and everything we needed. The pictures online were nice but in real life, it was a real gem. Can't wait to visit again."
United States
Victoria H.
$210 nightly
The price is $232
Dec 13 - Dec 14
Total with taxes and fees
Winetrail Cabin - SIU, Giant City SP, Shawnee Forest, & Cedar Lake minutes away!

Cabin in Anna

9.8 out of 10, Exceptional, (155)
"Our 2nd time staying here and it was perfect"
United States
machelle p.
$282 nightly
The price is $284
Dec 8 - Dec 9
Total with taxes and fees
Contemporary Glamping with Native American Appeal
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Cape Girardeau County Hotel Reviews

Find out more about Cape Girardeau County

Discover your perfect Cape Girardeau County vacation rental with Expedia

How many vacation rentals are available in Cape Girardeau County?


Expedia has plenty of vacation rentals to choose from in and around  Cape Girardeau County, so you’re guaranteed to find the right one for you. 


How much is a vacation rental in Cape Girardeau County?


The selection of Cape Girardeau County vacation rentals we have selected for you start as low as $101 per night. Entering your travel dates in the search wizard you might find even better deals!


What type of vacation rental can I get in Cape Girardeau County?


Vacation rentals in Cape Girardeau County come in all shapes and sizes, and your options depend on your chosen travel dates. You could entertain in a blissful vacation home, chill in a private apartment, or find family fun at a resort. Expedia offers a superb choice of Cape Girardeau County vacation rentals to suit everyone. 


Why should I choose a vacation rental in Cape Girardeau County?


Expedia’s vacation rentals provide cozy comforts you can sink into on your own schedule. You’ll enjoy your own space in a property with a kitchen, a pool, a garden etc. Maybe you’ll prefer somewhere with a spa or kids activities. A Cape Girardeau County vacation rental often works out to be a fantastic, cost-effective option for groups and families visiting for a few nights or longer. And if a hotel room is just too small, get a vacation rental with multiple bedrooms and shared living spaces to kick back in. 


How do I find the best deal on a vacation rental in Cape Girardeau County?


Find vacation rentals in Cape Girardeau County by viewing Expedia’s latest deals, or enter your travel dates and use the filters to select by amenities, price, or rating. Dive into the reviews to get a true feeling of which is your favorite vacation rental in Cape Girardeau County.  


What amenities are available in a vacation rental in Cape Girardeau County?


The choice is yours! Perhaps you love cooking in a well-equipped kitchen. Or maybe a late breakfast and a swimming pool is more your thing. Of course, there’s always the treat of having your own hot tub. Expedia has a vast range of amenities in Cape Girardeau County vacation rentals designed to suit every budget and trip type.


When is the best time to stay in a vacation rental in Cape Girardeau County?   


Everytime is a great time to head to Cape Girardeau County! Staying in a Cape Girardeau County vacation rentals you will always find lots going on to keep you entertained. 


Why book a vacation rental with Expedia?


Expedia has locked in amazing deals on a huge selection of impressive vacation rentals in Cape Girardeau County. We give you the information and inspiration you need all in one place. With so many properties to choose from, you know you can book your perfect Cape Girardeau County vacation rental with confidence. ANd don’t forget, if you bundle with a flight or a car rental in Cape Girardeau County, you can save even more.


Can I cancel my vacation rental through Expedia?  


Yes, you can cancel or change your Cape Girardeau County vacation rental by contacting your property manager directly. Contact details are easy to find on your itinerary in Trips. For more information, check out our Customer Service Portal and we’ll help you get everything sorted.