---
title: "$271 Cheap Flights to Cayos Zapatilla - Expedia"
description: "Looking for cheap flights to Cayos Zapatilla? Many airlines offer no change fee on selected flights and book now to earn your airline miles on top of our rewards! Find great 2026 Cayos Zapatilla flight deals now!"
canonical: "https://www.expedia.com/Cheap-Flights-To-Cayos-Zapatilla.d6286134.Travel-Guide-Flights"
language: en-US
market: US
currency: USD
prices_as_of: 2026-11-13T04:07:03Z
---

# $271 Cheap Flights to Cayos Zapatilla
![A clear turquoise sea, a sandy beach, and a dense forested island.](https://images.trvl-media.com/place/6286134/443bad9e-c57b-4b6d-aec8-29e5bf3e9898.jpg?impolicy=fcrop&w=1200&h=500&q=medium)

[View $271 flight on Wed, Apr 14, 2027](https://www.expedia.com/Flights-Search?leg1=from:MIA,to:PTY,departure:4/14/2027TANYT&trip=oneway&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&flp=mdl:flights-flex-module,price:270.75&airProductToken=AQoxCi8Iw5oBEgMyNDYYjAIg78QBKLeyqgMw8rOqAzhMQABYAWoDQkFTcghMTEE5T1oyUxIKCAEQARgBKgJDTRgBIgQIARABKAIoAygEMAs)

## Popular airlines

Avianca

American Airlines

Copa

Delta

United

Aeromexico

Air France

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## How much is the cheapest flight to Cayos Zapatilla?

Prices were available within the past 7 days and start at $271 for one-way flights and $567 for roundtrip, for the period specified. Prices and availability are subject to change.

All deals

One way

Roundtrip

[Select United flight, departing Mon, Mar 1 from Columbus to Panama City, returning Thu, Mar 4, priced at $687 Found 5 hours ago](https://www.expedia.com/Flights-Search?leg1=from:CMH,to:PTY,departure:3/1/2027TANYT&leg2=from:PTY,to:CMH,departure:3/4/2027TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&flp=mdl:flights-flex-module,price:686.59&airProductToken=AQpjCi8I1YIBEgQzNDA4GII7IMSNASjIxqYDMLXHpgM4S0AAWAFqAkJFcghLTlg2QTBCTAowCNWCARIEMTAyMRjEjQEg78QBKIPIpgMwvsqmAzhLQAFYAWoCQkVyCEtOWDZBMEJMCmEKLwjVggESBDEyNDkY78QBIIg4KIPnpgMwh-mmAzhLQABYAWoCQkVyCEtOWDZBMEJMCi4I1YIBEgQyMDg2GIg4III7KNvspgMw-u2mAzhLQAFYAWoCQkVyCEtOWDZBMEJMEgoIARABGAEqAlVBGAEiBAgBEAEoAigDKAQwAQ)

Mon, Mar 1 - Thu, Mar 4 · CMH · PTY · Roundtrip

[Select American Airlines flight, departing Tue, Mar 23 from Columbus to Panama City, returning Wed, Mar 31, priced at $687 Found 8 hours ago](https://www.expedia.com/Flights-Search?leg1=from:CMH,to:PTY,departure:3/23/2027TANYT&leg2=from:PTY,to:CMH,departure:3/31/2027TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&flp=mdl:flights-flex-module,price:686.59&airProductToken=AQpmCjEIwYIBEgQzNDM3GII7IIwCKPi6qAMworyoAzhCQABYAWoFQkFTSUNyCFFMWDVBQkJaCjEIwYIBEgMzMzEYjAIg78QBKOW9qAMwrL-oAzhCQAFYAWoFQkFTSUNyCFFMWDVBQkJaCmYKMQjBggESAzY0MBjvxAEgjAIo6JmpAzCvm6kDOEJAAFgBagVCQVNJQ3IIUUxYNUFCQloKMQjBggESBDM2MDcYjAIggjsoqZypAzDhnakDOEJAAVgBagVCQVNJQ3IIUUxYNUFCQloSCggBEAEYASoCQUEYASIECAEQASgCKAMoBDAL)

Tue, Mar 23 - Wed, Mar 31 · CMH · PTY · Roundtrip

[Select Delta flight, departing Tue, Apr 13 from Columbus to Panama City, returning Tue, Apr 20, priced at $687 Found 2 days ago](https://www.expedia.com/Flights-Search?leg1=from:CMH,to:PTY,departure:4/13/2027TANYT&leg2=from:PTY,to:CMH,departure:4/20/2027TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&flp=mdl:flights-flex-module,price:686.59&airProductToken=AQpvCjUIxJgBEgQyNDY5GII7IOBcKJinqgMw%5FKeqAzhFQABYAWoJTUFJTkJBU0lDcghVTlhRME5CWgo2CMSYARIEMTc1ORjgXCDvxAEog6mqAzD4qqoDOEVAAVgBaglNQUlOQkFTSUNyCFVOWFEwTkJaCm8KNgjEmAESBDE3NTgY78QBIOBcKK36qgMwrPyqAzhFQABYAWoJTUFJTkJBU0lDcghVTlhRME5CWgo1CMSYARIEMTQ3ORjgXCCCOyjtgasDMMyCqwM4RUABWAFqCU1BSU5CQVNJQ3IIVU5YUTBOQloSDAgBEAEYASoCREwyABgBIgQIARABKAIoAygEMAE)

Tue, Apr 13 - Tue, Apr 20 · CMH · PTY · Roundtrip

[Select United flight, departing Mon, Feb 8 from Columbus to Panama City, returning Mon, Feb 15, priced at $692 Found 7 hours ago](https://www.expedia.com/Flights-Search?leg1=from:CMH,to:PTY,departure:2/8/2027TANYT&leg2=from:PTY,to:CMH,departure:2/15/2027TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&flp=mdl:flights-flex-module,price:691.09&airProductToken=AQpgCi0I1YIBEgM1MTgYgjsgiDgo49ekAzCi2aQDOEtAAFgBagJCRXIIS05YNkEwQkwKLwjVggESBDEwMzQYiDgg78QBKIvcpAMwht6kAzhLQAFYAWoCQkVyCEtOWDZBMEJMCpEBCi8I1YIBEgQxMDMzGO%5FEASCIOCi1q6UDMMCtpQM4S0AAWAFqAkJFcghLTlg2QTBCTAouCNWCARIEMTMyNhiIOCCuHCi5rqUDMNWvpQM4S0ABWAFqAkJFcghLTlg2QTBCTAouCNWCARIEMzUxMhiuHCCCOyi%5Fs6UDMKK0pQM4S0ABWAFqAkJFcghLTlg2QTBCTBIKCAEQARgBKgJVQRgBIgQIARABKAIoAygEMAE)

Mon, Feb 8 - Mon, Feb 15 · CMH · PTY · Roundtrip

[Select American Airlines flight, departing Wed, Mar 24 from Columbus to Panama City, returning Wed, Apr 7, priced at $692 Found 3 days ago](https://www.expedia.com/Flights-Search?leg1=from:CMH,to:PTY,departure:3/24/2027TANYT&leg2=from:PTY,to:CMH,departure:4/7/2027TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&flp=mdl:flights-flex-module,price:691.59&airProductToken=AQpmCjEIwYIBEgQzNDM3GII7IIwCKJjGqAMwwseoAzhCQABYAWoFQkFTSUNyCFFMWDVBQkJaCjEIwYIBEgMzMTkYjAIg78QBKJbIqAMw1cmoAzhCQAFYAWoFQkFTSUNyCFFMWDVBQkJaCmcKMgjBggESBDI5NjQY78QBIIwCKOnnqQMwrempAzhCQABYAWoFQkFTSUNyCFFMWDVBQkJaCjEIwYIBEgQzNDYzGIwCIII7KJvrqQMwy-ypAzhCQAFYAWoFQkFTSUNyCFFMWDVBQkJaEgwIARABGAEqAkFBMgAYASIECAEQASgCKAMoBDAL)

Wed, Mar 24 - Wed, Apr 7 · CMH · PTY · Roundtrip

[Select Delta flight, departing Tue, Apr 13 from Columbus to Panama City, returning Tue, Apr 20, priced at $697 Found 2 days ago](https://www.expedia.com/Flights-Search?leg1=from:CMH,to:PTY,departure:4/13/2027TANYT&leg2=from:PTY,to:CMH,departure:4/20/2027TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&flp=mdl:flights-flex-module,price:696.08&airProductToken=AQpvCjUIxJgBEgQyNzg2GII7IOBcKNutqgMwx66qAzhFQABYAWoJTUFJTkJBU0lDcghVTlhRME5CWgo2CMSYARIEMTc1ORjgXCDvxAEoo7SqAzCYtqoDOEVAAVgBaglNQUlOQkFTSUNyCFVOWFEwTkJaCm8KNgjEmAESBDE3NTgY78QBIOBcKK36qgMwrPyqAzhFQABYAWoJTUFJTkJBU0lDcghVTlhRME5CWgo1CMSYARIEMzEyMBjgXCCCOyiL%5FaoDMOX9qgM4RUABWAFqCU1BSU5CQVNJQ3IIVU5YUTBOQloSDAgBEAEYASoCREwyABgBIgQIARABKAIoAygEMAE)

Tue, Apr 13 - Tue, Apr 20 · CMH · PTY · Roundtrip

[Select American Airlines flight, departing Fri, Apr 30 from Columbus to Panama City, returning Fri, May 7, priced at $697 Found 1 day ago](https://www.expedia.com/Flights-Search?leg1=from:CMH,to:PTY,departure:4/30/2027TANYT&leg2=from:PTY,to:CMH,departure:5/7/2027TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&flp=mdl:flights-flex-module,price:696.59&airProductToken=AQpnCjEIwYIBEgQzNjY3GII7IIwCKLjmqwMw3eerAzhCQABYAWoFQkFTSUNyCFFMWDVBQkJaCjIIwYIBEgQyNzk3GIwCIO%5FEASjG6KsDMIDqqwM4QkABWAFqBUJBU0lDcghRTFg1QUJCWgpnCjIIwYIBEgQyOTY0GO%5FEASCMAiipuawDMO26rAM4QkAAWAFqBUJBU0lDcghOTFg1QUJCWgoxCMGCARIEMzUzMBiMAiCCOyjcu6wDMI-9rAM4QkABWAFqBUJBU0lDcghOTFg1QUJCWhIKCAEQARgBKgJBQRgBIgQIARABKAIoAygEMAs)

Fri, Apr 30 - Fri, May 7 · CMH · PTY · Roundtrip

[Select United flight, departing Mon, Mar 1 from Columbus to Panama City, returning Thu, Mar 4, priced at $699 Found 5 hours ago](https://www.expedia.com/Flights-Search?leg1=from:CMH,to:PTY,departure:3/1/2027TANYT&leg2=from:PTY,to:CMH,departure:3/4/2027TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&flp=mdl:flights-flex-module,price:698.09&airProductToken=AQpzCjcI1YIBEgQzNDU3GII7IMSNASi4xKYDMKjFpgM4S0AAWAFqCjFfYmFzaWNlY29yCEtOWDZBMEJMCjgI1YIBEgQxMDIxGMSNASDvxAEog8imAzC-yqYDOEtAAFgBagoxX2Jhc2ljZWNvcghLTlg2QTBCTBIKCAEQARgBKgJVQRgBIgQIARABKAIoAygEMAs)

Mon, Mar 1 - Thu, Mar 4 · CMH · PTY · Roundtrip

[Select American Airlines flight, departing Tue, Mar 23 from Columbus to Panama City, returning Wed, Mar 31, priced at $702 Found 8 hours ago](https://www.expedia.com/Flights-Search?leg1=from:CMH,to:PTY,departure:3/23/2027TANYT&leg2=from:PTY,to:CMH,departure:3/31/2027TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&flp=mdl:flights-flex-module,price:701.26&airProductToken=AQpmCjEIwYIBEgQzMzUwGII7IIwCKJ3BqAMwwsKoAzhCQABYAWoFQkFTSUNyCFFMWDVBQkJaCjEIwYIBEgMzMzEYjAIg78QBKIXJqAMwzMqoAzhCQAFYAWoFQkFTSUNyCFFMWDVBQkJaCmYKMQjBggESAzY0MBjvxAEgjAIo6JmpAzCvm6kDOEJAAFgBagVCQVNJQ3IIUUxYNUFCQloKMQjBggESBDM2MDcYjAIggjsoqZypAzDhnakDOEJAAVgBagVCQVNJQ3IIUUxYNUFCQloSCggBEAEYASoCQUEYASIECAEQASgCKAMoBDAL)

Tue, Mar 23 - Wed, Mar 31 · CMH · PTY · Roundtrip

[Select Avianca flight, departing Fri, Mar 5 from Columbus to Panama City, returning Sun, Mar 14, priced at $1,188 Just found](https://www.expedia.com/Flights-Search?leg1=from:CMH,to:PTY,departure:3/5/2027TANYT&leg2=from:PTY,to:CMH,departure:3/14/2027TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&flp=mdl:flights-flex-module,price:1188.00&airProductToken=AQqkAQo9CMGsARIEMjA1MhiCOyCIGCj78KYDMNHxpgM4T0AAWAFqBUxJR0hUcghPTFJCMUJSRnoKCNWCARIEMzQzMAowCMGsARIDNTgzGIgYIJJYKOX1pgMw-PemAzhPQAFYAWoFTElHSFRyCE9MUkIxQlJGCjEIwawBEgMzMTcYklgg78QBKLH5pgMwrvqmAzhPQAFYAWoFTElHSFRyCE9MUkIxQlJGCqMBCjEIwawBEgMzMTYY78QBIJJYKPbVpwMw7tanAzhPQABYAWoFTElHSFRyCE9MUkIxQlJGCjAIwawBEgM1ODQYklggiBgouNmnAzC326cDOE9AAVgBagVMSUdIVHIIT0xSQjFCUkYKPAjBrAESBDIyMjcYiBgggjsoj-SnAzDk5KcDOE9AAVgBagVMSUdIVHIIT0xSQjFCUkZ6CQjVggESAzYzMhIMCAEQARgBKgJBVjIAGAEiBAgBEAEoAigDKAQwAQ)

Fri, Mar 5 - Sun, Mar 14 · CMH · PTY · Roundtrip

## Frequently Asked Questions

### What month is the cheapest to fly to Cayos Zapatilla?

The cheapest month to fly to Cayos Zapatilla is February when demand is low. Off-peak months are often when you'll find cheap fares. To save money, avoid flying during school breaks and major holidays.

### Which US cities fly direct to Cayos Zapatilla?

You can fly to Cayos Zapatilla directly from 17 US cities. To find a nonstop journey, select "Direct flights only" when browsing for flights to Cayos Zapatilla on Expedia. Then, compare the options and find the best departure from one of these cities:

- Miami
- Orlando
- Los Angeles
- Washington
- New York

### How to find a cheap flight to Cayos Zapatilla?

If you're eager to find cheap flights to Cayos Zapatilla, consider traveling outside of peak season. Booking in advance is also likely to save you money. Or, fly on a different day — flights on a Thursday are on average 16% cheaper than Sunday options.\* Sign up to receive price alerts on the [Expedia app](https://www.expedia.com/app) and get notifications as soon as fares fall.

*\*Best day of the week to book, depart and ideal booking window recommendations based on average round-trip ticket prices for January through August 2023, sourced from Airline Reporting Corporation's (ARC) global airline sales database. Percentages noted are averages.*

### How to get a cheap last-minute flight to Cayos Zapatilla?

Staying flexible with your travel plans may help you find last-minute offers on cheap flights to Cayos Zapatilla. To see all the available options, consider looking at different ticket types, changing your Cayos Zapatilla trip dates, flying out of an alternative airport or using another carrier.

### How far in advance should I book a flight to Cayos Zapatilla?

Find the travel dates you want and a price that fits your budget by booking your domestic flight to Cayos Zapatilla up to 28 days in advance. Search for tickets two to four months ahead if you're traveling to Cayos Zapatilla from an international destination.\*

*\*Best day of the week to book, depart and ideal booking window recommendations based on average round-trip ticket prices for January through August 2023, sourced from Airline Reporting Corporation's (ARC) global airline sales database. Percentages noted are averages.*

### Which day of the week is the cheapest day to buy a plane ticket to Cayos Zapatilla?

Sundays are typically the best day to book a cheap flight to Cayos Zapatilla, with savings of about 8% on average compared to Fridays. If you purchase tickets on a Friday, expect to pay a higher price as this is often the most expensive day.\*

*\*Best day of the week to book, depart and ideal booking window recommendations based on average round-trip ticket prices for January through August 2023, sourced from Airline Reporting Corporation's (ARC) global airline sales database. Percentages noted are averages.*

### Which airlines fly to Cayos Zapatilla?

With a good range of airlines that fly to Cayos Zapatilla, the choice is all yours:

- Copa Airlines - 932 flights to Cayos Zapatilla each month, including 932 flights to Tocumen Intl. Airport (PTY) per month.
- United Airlines - 152 flights to Cayos Zapatilla each month, including 152 flights to Tocumen Intl. Airport (PTY) per month.
- Delta Air Lines - 30 flights to Cayos Zapatilla each month, including 30 flights to Tocumen Intl. Airport (PTY) per month.

### Can I save money by booking a Cayos Zapatilla trip package?

Book a [Cayos Zapatilla flight and hotel package deal](https://www.expedia.com/Cayos-Zapatilla.d6286134.Destination-Travel-Guides) on Expedia, and you can make significant savings. It's easy to bundle your hotel and flight, and you can even add tours and car rentals to create your own customized Cayos Zapatilla vacation. Plus, there's nothing like the convenience of booking everything in one place.

### Can I change or cancel my flight to Cayos Zapatilla?

It's often possible to change or cancel your flight to Cayos Zapatilla. Many airlines let you cancel your flight for free within 24 hours of making your booking. However, some flights are non-refundable, and airlines may offer you a credit toward future flights rather than a direct refund. To find cheap flights to Cayos Zapatilla with flexible change policies, select "No cancel fee" or "Changes included" when you search. Looking for more information? Head to our [Customer Service Portal](https://www.expedia.com/service/?langid=1033).

## Travel information

| Airlines serving | Avianca, American Airlines, Copa, Delta, United, Aeromexico, Air France, KLM, Turkish Airlines, Iberia, Air Europa, WestJet, Lufthansa, GOL Linhas Aereas S.A., British Airways, Cayman Airways, EVA Airways, Caribbean Airlines, Qatar Airways, Emirates, Korean Air, Etihad Airways, China Eastern Airlines, EL AL Israel Airlines, Azul |
| ---------------- | ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ |
| Popular airline  | Avianca                                                                                                                                                                                                                                                                                                                                    |
| Roundtrip price  | $687                                                                                                                                                                                                                                                                                                                                       |

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- [Visit Isla Bastimentos](https://www.expedia.com/Isla-Bastimentos.dx6238840)
- [Visit Water Cay](https://www.expedia.com/Water-Cay.dx3000665402)
- [Visit Cayos Zapatilla](https://www.expedia.com/Cayos-Zapatilla.dx6286134)
- [Playa Larga](https://www.expedia.com/Playa-Larga-Bocas-del-Toro-Province.d553248623461799700.Vacation-Attraction)
- [All inclusive Vacation Packages Isla Bastimentos](https://www.expedia.com/lp/theme-vacations/all-inclusive-vacations/6238840/Isla-Bastimentos)
- [Nivida Bat Cave](https://www.expedia.com/Nivida-Bat-Cave-Bastimentos.d553248621532965359.Vacation-Attraction)
- [Visit Isla Popa](https://www.expedia.com/Isla-Popa.dx6144989)
- [Auto Rent Rental Cars in Isla Bastimentos](https://www.expedia.com/Auto-Rent-Car-Rentals-In-Isla-Bastimentos.d6238840-c1006.Car-Rental-Guide-Suppliers)
- [Isla Bastimentos Vacation Rentals](https://www.expedia.com/Isla-Bastimentos-Vacation-Rentals.d6238840.Travel-Guide-VacationRentals)
- [Things to do in Bastimentos](https://www.expedia.com/Things-To-Do-In-Bastimentos.d829296964305711104.Travel-Guide-Activities)
- [Things to do in Isla Bastimentos](https://www.expedia.com/Things-To-Do-In-Isla-Bastimentos.d6238840.Travel-Guide-Activities)

## Trending flights to Cayos Zapatilla

Prices were available within the past 7 days and start at $271 for one-way flights and $567 for roundtrip, for the period specified. Prices and availability are subject to change.

All deals

One way

Roundtrip

[Select Copa flight, departing Sat, Feb 27 from Miami to Panama City, returning Wed, Mar 3, priced at $567 Just found](https://www.expedia.com/Flights-Search?leg1=from:MIA,to:PTY,departure:2/27/2027TANYT&leg2=from:PTY,to:MIA,departure:3/3/2027TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&flp=mdl:flights-flex-module,price:566.99&airProductToken=AQoxCi8Iw5oBEgMxNzMYjAIg78QBKOSspgMwoa6mAzhUQABYAWoDQkFTcghUTEE5VloyUwoxCi8Iw5oBEgM0NDEY78QBIIwCKKTgpgMw3-GmAzhUQABYAWoDQkFTcghUTEE5VloyUxIKCAEQARgBKgJDTRgBIgQIARABKAIoAygEMAs)

Sat, Feb 27 - Wed, Mar 3 · MIA · PTY · Roundtrip

\*Available to One Key members.

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