La Mesilla Vacation Rentals

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Our top choices for La Mesilla vacation rentals

9.8 out of 10, Exceptional, (59)
"Clean and nice, would stay here again."
United States
Randy C.
$239 nightly
The price is $273
Dec 17 - Dec 18
Total with taxes and fees
Gorgeous Condo Near Historic Santa Fe Plaza!
10.0 out of 10, Exceptional, (190)
"Incredible place"
United States
Matt K.
$429 nightly
The price is $478
Dec 17 - Dec 18
Total with taxes and fees
Private Upscale Mountain View Retreat just 12 Minutes From The Santa Fe Plaza.
10.0 out of 10, Exceptional, (5)
$209 nightly
The price is $232
Dec 17 - Dec 18
Total with taxes and fees
Centrally-located, sweeping mountain views!
10.0 out of 10, Exceptional, (8)
"Located at the end of a private road, at the foot of a mesa. Scenery was gorgeous. The patio was serene; great place to watch the sunset. "
United States
Helen M.
$214 nightly
The price is $238
Dec 17 - Dec 18
Total with taxes and fees
Peaceful Suite in Desert Inn- San Juan Queen Room
9.2 out of 10, Wonderful, (5)
"The fresh flowers and bottle of wine were the perfect start to a long weekend stay. Easy to relax and enjoy family time. Thanks again Casa Salano."
United States
Maureen M.
$343 nightly
The price is $392
Jan 13 - Jan 14, 2026
Total with taxes and fees
Historic Plaza Oasis Within Walking Distance, King Bed,Office,Foosball
10.0 out of 10, Exceptional, (5)
"The casita was so well equipped with everything you need. Great views in a very quiet neighborhood. "
United States
Roy
$160 nightly
The price is $171
Dec 21 - Dec 22
Total with taxes and fees
Premier Host ★ Beautiful, Spotless & Perfectly Located
$522 nightly
The price is $593
Dec 17 - Dec 18
Total with taxes and fees
17 Mi to Ski Santa Fe! North Side 'Tiffany House'
10.0 out of 10, Exceptional, (19)
"House was clean and in a beautiful area. Would definitely stay again. "
United States
Shelly A.
$378 nightly
The price is $421
Dec 21 - Dec 22
Total with taxes and fees
Happy Ram: Views! Beautiful. Peaceful. Upscale. Secluded.
8.0 out of 10, Very Good, (2)
"We came on a Sunday night, hard to find on app, and we were completely alone until after dark, as the restaurant is closed on Sunday evening. We loved the room-it could use a microwave especially as it is so isolated)and the views are fabulous"
United States
judith
$248 nightly
The price is $275
Dec 17 - Dec 18
Total with taxes and fees
Peaceful Suite in Desert Inn-Santa Clara King Room
9.4 out of 10, Exceptional, (3)
"The second we opened our car door we knew this place was magical. Chef Graham who has the property is one incredible and talented man. If you're looking for beauty, peace and decompression then head their way...you won't go wrong."
United States
gilbert M.
$226 nightly
The price is $250
Dec 21 - Dec 22
Total with taxes and fees
Peaceful Suite in Desert Inn- Black Mesa King Room
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top La Mesilla Hotel Reviews

Find out more about La Mesilla

Everything you need to know about La Mesilla vacation rentals

Whether you’re excited for the perfect family vacation, a romantic getaway for two, or the ultimate city break, we’ve got the La Mesilla vacation rental for you. At Expedia, you can take your pick from private vacation homes, apartments, condos, resorts, cabins, villas, motels. The list goes on, and on …and on.

There’s just as wide a choice of amenities, too. Maybe you’re dreaming of your own pool, long evenings in a hot tub, or watching the kids laugh through the day at a waterpark. Maybe you just want a quiet retreat in a pet-friendly apartment. Well, we can help you find it. Hunt out the perfect La Mesilla vacation rental for you by simply entering your desired dates. Then check your favorite filters to narrow down your search.

La Mesilla vacation rentals: An excellent choice for every season

Whenever you want to travel, a warm welcome awaits you in La Mesilla. If you’re looking for a little peace, consider booking during the quieter low season months. For more hustle and bustle, you may prefer to visit La Mesilla in high season.

Prices vary throughout the year. Your chosen location, property type, and amenities will impact the cost of your trip, too. The selection of properties we have chosen for you start as low as $232 per night. Rates vary depending on your travel dates, location, and amenities so make a search and you might find even better deals!

How to find incredible deals on La Mesilla rentals

At Expedia, we put the best La Mesilla vacation rentals in one place. All you need to do is take your pick. And as we offer book now, pay later options, as well as free cancellation on some properties, you can plan your trip with total peace of mind. You’ll always find a great deal with Expedia.

To find some top La Mesilla rental deals, enter your travel dates, and sort your search results by price. You can also filter by budget, so you only see accommodation in your ballpark. Next, add any filters you want—and just like that, you’ve built your dream La Mesilla vacation.

If you’re looking for a little inspiration, browse our latest incredible offers, or use the map to view all accommodation in and around La Mesilla. And to unlock even more fantastic deals, bundle your accommodation, flights, and car rental together to save and book with Expedia in complete confidence.

Frequently asked questions

Are there vacation rentals in La Mesilla?

Yes, we offer vacation rentals near popular local attractions in La Mesilla, or you can go with a more secluded option if you're looking for relaxation.

What's the top vacation rental that La Mesilla has to offer?

Mid-century Modern
3 min for plaza
: This vacation home rental near La Mesilla is located in the mountains and has a fireplace, a patio, and a barbecue grill to put you at ease in your new surroundings. Kitchen amenities include a dishwasher, a fridge, and a stovetop.

What can I see and do in La Mesilla?

Explore the area and family-friendly sights such as Bradbury Science Museum, or get out into nature at a spot like Nambe Falls. Cities of Gold Casino and Towa Golf Resort are a couple of places you'll find in the larger area.

What are vacation rentals like in La Mesilla?

Vacation rentals are privately owned accommodations you can stay in for a short or long stay in La Mesilla. Vacation rentals offer extras such as laundry facilities and kitchens so you'll have all the comforts of home. If you're concerned about a sanitized environment, vacation rentals can provide a sense of security away from shared hotel elevators and lobbies bustling with people while still allowing you the experience of travel. You'll also find more space in a vacation rental than in a traditional hotel, which makes a vacation rental a popular choice for a family trip.