Title: Visit Lilbourn: 2026 Travel Guide for Lilbourn, Missouri | Expedia.com [Hotels in Lilbourn](https://expedia.com/Lilbourn-Hotels.d553248634983590625.Travel-Guide-Hotels)[Vacation Rentals in Lilbourn](https://expedia.com/Lilbourn-Vacation-Rentals.d553248634983590625.Travel-Guide-VacationRentals)[Car Rentals in Lilbourn](https://expedia.com/Car-Rentals-In-Lilbourn.d553248634983590625.Car-Rental-Guide)[Lilbourn Vacation Packages](https://expedia.com/Lilbourn.d553248634983590625.Destination-Travel-Guides) # Lilbourn, MO ## Travel Guide ## Visit Lilbourn - Lilbourn Hotel Deals - Vacation Rentals in Lilbourn ![Drury Inn & Suites Sikeston, MO](https://images.trvl-media.com/lodging/1000000/30000/24300/24210/85184a8e_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Drury Inn & Suites Sikeston, MO 2608 East Malone Ave, Miner Sikeston MO $94 nightly $108 total Apr 5 - Apr 6 Total with taxes and fees Book a stay at this business-friendly hotel in Sikeston. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ... 9.4/10 Exceptional! (1,002 reviews) We will definitely be back! We travel from Wisconsin to Texas at least 2 times a year to visit family and we like to break our trip up with an overnight stay. This Drury Inn in Siikeston, Missouri will be our home away from Reviewed on Mar 28, 2026 [](https://expedia.com/Hotel-Search?startDate=4%2F5%2F2026&endDate=4%2F6%2F2026&selected=24210&PinnedHotelID=24210&HadPinnedHotel=true®ionId=553248634983590625) ![Hampton Inn Sikeston](https://images.trvl-media.com/lodging/26000000/25180000/25178200/25178175/77525d07_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Hampton Inn Sikeston 1240 Commerce Drive Sikeston MO $99 nightly $112 total Apr 12 - Apr 13 Total with taxes and fees Stay at this hotel in Sikeston. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular attractions Central ... 9/10 Wonderful! (515 reviews) Lovely facilities. Friendly staff. Reviewed on Mar 27, 2026 [](https://expedia.com/Hotel-Search?startDate=4%2F12%2F2026&endDate=4%2F13%2F2026&selected=25178175&PinnedHotelID=25178175&HadPinnedHotel=true®ionId=553248634983590625) ![Drury Inn & Suites Hayti Caruthersville](https://images.trvl-media.com/lodging/1000000/50000/42200/42109/ff3e4031_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Drury Inn & Suites Hayti Caruthersville 1317 E Highway 84 Hayti MO $94 nightly $107 total Apr 5 - Apr 6 Total with taxes and fees Book a stay at this business-friendly hotel in Hayti. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ... 9.4/10 Exceptional! (1,000 reviews) Friendly staff Reviewed on Mar 23, 2026 [](https://expedia.com/Hotel-Search?startDate=4%2F5%2F2026&endDate=4%2F6%2F2026&selected=42109&PinnedHotelID=42109&HadPinnedHotel=true®ionId=553248634983590625) [See all 77 properties in Lilbourn](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.DestinationExperience&startDate=3%2F29%2F2026&endDate=3%2F30%2F2026®ionId=553248634983590625) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. ![Duck Hunting, Fishing or Relaxing Family Vacation](https://images.trvl-media.com/lodging/37000000/36090000/36089000/36088974/d93cc56b_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Duck Hunting, Fishing or Relaxing Family Vacation Hornbeak TN Stay at this vacation home in Hornbeak. Enjoy a garden, laundry facilities, and patios. Popular attractions Willow Towhead and Rat Island are located ... 10/10 Exceptional! (226 reviews) The best stocked house we’ve ever stayed at while fishing Reelfoot!!! Highly recommend and will certainly book again!!! Reviewed on Mar 20, 2026 [](https://expedia.com/Hornbeak-Hotels-Duck-Hunting.h36088974.Hotel-Information) ![Come and relax at the Refuge at beautiful Reelfoot Lake!](https://images.trvl-media.com/lodging/84000000/83580000/83572000/83571978/0a58d14b_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Come and relax at the Refuge at beautiful Reelfoot Lake! Hornbeak TN Enjoy free WiFi, laundry facilities, and patios. Popular attractions Willow Towhead and Rat Island are located nearby. 9.4/10 Exceptional! (27 reviews) We loved The Refuge. We just came down for a weekend fishing trip with our boys, But it would be so perfect for someone who wants to come down with a group of friends, as there's plenty of twin beds. We loved it and would definitely stay again. Reviewed on Mar 23, 2026 [](https://expedia.com/Hornbeak-Hotels-Enjoy-Beautiful-Sunsets-At-The-HUT-2-At-Beautiful-Reelfoot-Lake.h83571978.Hotel-Information) ![Beautiful Reelfoot Lake](https://images.trvl-media.com/lodging/76000000/75270000/75267600/75267595/4d50be35_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Beautiful Reelfoot Lake Tiptonville TN Stay at this vacation home in Tiptonville. Enjoy free WiFi, a garden, and laundry facilities. Popular attractions Campbell's Point and Reelfoot Lake State Park ... 10/10 Exceptional! (98 reviews) Very warm nice beautiful home. Will for sure use to stay again. Thank you Chris for everything. Reviewed on Mar 22, 2026 [](https://expedia.com/Tiptonville-Hotels-Beautiful-Reelfoot-Lake.h75267595.Hotel-Information) [See all properties in Lilbourn](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.DestinationExperience®ionId=553248634983590625&sort=VACATION_RENTAL) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. ## Check Lilbourn hotel availability [Tonight ](https://expedia.com/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=553248634983590625&startDate=2026-03-28&endDate=2026-03-29)[Mar 28 - Mar 29](https://expedia.com/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=553248634983590625&startDate=2026-03-28&endDate=2026-03-29) [Tomorrow night ](https://expedia.com/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=553248634983590625&startDate=2026-03-29&endDate=2026-03-30)[Mar 29 - Mar 30](https://expedia.com/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=553248634983590625&startDate=2026-03-29&endDate=2026-03-30) [Next weekend ](https://expedia.com/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=553248634983590625&startDate=4%2F3%2F2026&endDate=4%2F5%2F2026)[Apr 3 - Apr 5](https://expedia.com/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=553248634983590625&startDate=4%2F3%2F2026&endDate=4%2F5%2F2026) ## Cities near Lilbourn ![Mississippi River Walk at New Madrid. A magnificent view of the Mississippi river from atop of the levee. A steamboat is docked down river. . ](https://images.trvl-media.com/place/3000445315/970b11d9-266d-426a-9577-5e745e0939b7.jpg?impolicy=fcrop&w=512&h=288&q=medium) ### New Madrid - Cities near Lilbourn - Places of interest [Marston](https://expedia.com/Marston.dx55824)[Portageville](https://expedia.com/Portageville.dx183487)[Catron](https://expedia.com/Catron.dx3000349317)[Gideon](https://expedia.com/Gideon.dx3000349377)[Risco](https://expedia.com/Risco.dx3000349516)[New Madrid](https://expedia.com/New-Madrid.dx3000445315) - [Mississippi River ](https://expedia.com/Mississippi-River-United-States-of-America.d6209928.Vacation-Attraction) - [Reelfoot Lake ](https://expedia.com/Reelfoot-Lake-Tennessee.d553248635976195913.Vacation-Attraction) - [Reelfoot Lake State Park ](https://expedia.com/Reelfoot-Lake-State-Park-Tiptonville.d553248621532655205.Vacation-Attraction) - [Central Park ](https://expedia.com/Central-Park-Sikeston.d6305608.Vacation-Attraction) - [Black Island Conservation Area ](https://expedia.com/Black-Island-Conservation-Area-Hayti.d553248621560505648.Vacation-Attraction) - [Hayti Park ](https://expedia.com/Hayti-Park-Hayti.d6245776.Vacation-Attraction) - [Sikeston Depot Museum ](https://expedia.com/Sikeston-Depot-Museum-Sikeston.d6305602.Vacation-Attraction) - [Campbell's Point ](https://expedia.com/Campbells-Point-Tiptonville.d553248623744257771.Vacation-Attraction) - [Dexter Welcome Center Depot and Museum ](https://expedia.com/Dexter-Welcome-Center-Depot-And-Museum-Dexter.d553248621592342445.Vacation-Attraction) - [Hayti Pentecostal Holiness Church ](https://expedia.com/Hayti-Pentecostal-Holiness-Church-Hayti.d6245797.Vacation-Attraction) - [Marston Community Center ](https://expedia.com/Marston-Community-Center-Marston.d553248622945532712.Vacation-Attraction) - [The Heritage House ](https://expedia.com/The-Heritage-House-Dexter.d553248621592342444.Vacation-Attraction) - [Stoddard County Civil War Memorial Cemetery ](https://expedia.com/Stoddard-County-Civil-War-Memorial-Cemetery-Dexter.d553248621532655747.Vacation-Attraction) - [New Madrid Historical Museum ](https://expedia.com/New-Madrid-Historical-Museum-New-Madrid.d553248621532655748.Vacation-Attraction) - [Hunter-Dawson State Historic Site ](https://expedia.com/Hunter-Dawson-State-Historic-Site-New-Madrid.d553248621532655794.Vacation-Attraction) ![](https://a.travel-assets.com/mad-service/footer/bnaBanners/BEX_Footer.jpg) ## Go further with the Expedia app Save even more - get up to 20% on select hotels when you book on the app. Our app deals help you to save on trips so you can travel more and manage it all on the go. 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