Santo Domingo Vacation Rentals

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Vacation Rentals in Santo Domingo

Spacious 6-bedroom villa in wonderful Las Tablas with WiFi, AC

$594 nightly
The price is $594
Sep 7 - Sep 8
Total with taxes and fees
Spacious 6-bedroom villa in wonderful Las Tablas with WiFi, AC

DRONES PEDASI RANCH - BEACHFRONT, POOL, 3BRM - 5BATH + Whales Watching & Fishing

8.0 out of 10, Very Good, (2)
"Great for long walks on beach and shaded pool. Basic kitchen - we enjoyed our breakfasts and lunches at the house. Esteban is a wonderful host - very responsive and helpful. Comes with Bailey the Fox Hound - great beach buddy!"
DRONES PEDASI RANCH - BEACHFRONT, POOL, 3BRM - 5BATH + Whales Watching & Fishing

Private 3-bedroom villa in beautiful Azuero Peninsula with AC, pool, near beach

Private 3-bedroom villa in beautiful Azuero Peninsula with AC, pool, near beach

1st Floor Beach House Apartment just steps from the beach!

9.4 out of 10, Exceptional, (6)
"Although my visit was short the property had everything needed for a wonderful stay. The property manager was extremely helpful."
1st Floor Beach House Apartment just steps from the beach!

Resting cabin with a unique garden, swimming pool and Panamanian traditions.

10.0 out of 10, Exceptional, (1)
"We were impressed with the place, beautiful grounds, an outdoor kitchen, very close to attractions. The hosts were so friendly, it made our experience very special that we definitely want to return."
Resting cabin with a unique garden, swimming pool and Panamanian traditions.

Beautiful Beach House and Casita at Playa Uverito, Las Tablas Panama

9.2 out of 10, Wonderful, (5)
"Everything was as advertised, great location with a beautiful view. This is our second year staying here and there were several upgrades that made our stay better. Looking forward to our next visit to the beach."
Beautiful Beach House and Casita at Playa Uverito, Las Tablas Panama

Beautiful house in Costa Pedas

Beautiful house in Costa Pedas

2nd Floor Beach House Apartment just steps from the beach!

8.6 out of 10, Excellent, (4)
"Fully furnished. Newly remodeled. Very quiet. Bring your own beach chairs. Good shelling at low tide! Enjoy!"
2nd Floor Beach House Apartment just steps from the beach!

Beautiful Home in Residenciales Cubita

10.0 out of 10, Exceptional, (2)
"This house is so beautiful and comfortable, spacious and has great areas to chill and rest. The area around the house is very calm and quiet. Ivette is an amazing host, very responsive and was attentive to everything we needed during our stay. Will Definitely stay here again. "
Beautiful Home in Residenciales Cubita

Minimalist House In Chitre

Minimalist House In Chitre

Villas Don Pablo

3.0 star property
9.6 out of 10, Exceptional, (7)
"Ofrece todo lo necesario para una familia, en un ambiente seguro y tranquilo. "
Villas Don Pablo

Pedasi Nature Paradise

3.5 star property
8.4 out of 10, Very Good, (7)
"The property in still in a phase of construction/ remodel on one of the buildings but that did not hamper our stay at all. They were very attentive and accommodating. We had a booking issue with expedia and Antonio was great to compensate for the error and put us in a room when he had none. It all worked out great in the end Like to give a shout out to Cesar as well."
Pedasi Nature Paradise

Hogar fuera de casa! Una casa con todas las amenidades para disfrutar.

Hogar fuera de casa! Una casa con todas las amenidades para disfrutar.

Uverito Beach House is a 2 Bed/2 Bath house just steps from the beach!

8.0 out of 10, Very Good, (17)
"Was a great stay! We spent the winter there and will again next winter!!!"
Uverito Beach House is a 2 Bed/2 Bath house just steps from the beach!

Ocean Breeze Cove - Adults Only - Luxury Retreat

$204 nightly
The price is $204
Sep 7 - Sep 8
Total with taxes and fees
Ocean Breeze Cove - Adults Only - Luxury Retreat

A cozy 3-bedroom home in a natural setting

A cozy 3-bedroom home in a natural setting

The nature of Pedesi

The nature of Pedesi

3-bedroom, walk to town, spacious Villa

3-bedroom, walk to town, spacious Villa

Eye of Water Private Home with infinity pool and amazing views of Pacific Coast

Eye of Water Private Home with infinity pool and amazing views of Pacific Coast

3-bedroom, walk to town, spacious Villa

3-bedroom, walk to town, spacious Villa
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Santo Domingo Hotel Reviews

Find out more about Santo Domingo

Find out more about Santo Domingo

Everything you need to know about Santo Domingo vacation rentals

Whether you’re excited for the perfect family vacation, a romantic getaway for two, or the ultimate city break, we’ve got the Santo Domingo vacation rental for you. At Expedia, you can take your pick from private vacation homes, apartments, condos, resorts, cabins, villas, motels. The list goes on, and on …and on.

There’s just as wide a choice of amenities, too. Maybe you’re dreaming of your own pool, long evenings in a hot tub, or watching the kids laugh through the day at a waterpark. Maybe you just want a quiet retreat in a pet-friendly apartment. Well, we can help you find it. Hunt out the perfect Santo Domingo vacation rental for you by simply entering your desired dates. Then check your favorite filters to narrow down your search.

Santo Domingo vacation rentals: An excellent choice for every season

Whenever you want to travel, a warm welcome awaits you in Santo Domingo. If you’re looking for a little peace, consider booking during the quieter low season months. For more hustle and bustle, you may prefer to visit Santo Domingo in high season.

Prices vary throughout the year. Your chosen location, property type, and amenities will impact the cost of your trip, too. The selection of properties we have chosen for you start as low as $204 per night. Rates vary depending on your travel dates, location, and amenities so make a search and you might find even better deals!

How to find incredible deals on Santo Domingo rentals

At Expedia, we put the best Santo Domingo vacation rentals in one place. All you need to do is take your pick. And as we offer book now, pay later options, as well as free cancellation on some properties, you can plan your trip with total peace of mind. You’ll always find a great deal with Expedia.

To find some top Santo Domingo rental deals, enter your travel dates, and sort your search results by price. You can also filter by budget, so you only see accommodation in your ballpark. Next, add any filters you want—and just like that, you’ve built your dream Santo Domingo vacation.

If you’re looking for a little inspiration, browse our latest incredible offers, or use the map to view all accommodation in and around Santo Domingo. And to unlock even more fantastic deals, bundle your accommodation, flights, and car rental together to save and book with Expedia in complete confidence.

Frequently asked questions

Are there vacation rentals in Santo Domingo?

Yes, you can find vacation rentals close to top points of interest in Santo Domingo, or you can go with a more remote option if you're looking for a relaxing stay.

What's the top vacation rental that Santo Domingo has to offer?

Beautiful Beach House and Casita at Playa Uverito, Las Tablas Panama: This vacation home rental outside of Santo Domingo is located near the beach and has a balcony, a selection of games, and air-conditioning to put you at ease in your new surroundings. It has 4 bedrooms as well as a kitchen with a fridge, a stovetop, and a microwave, so you can cook with friends or family.

What can I see and do in Santo Domingo?

El Uverito Beach and Cerro La Teta are a couple of lovely local spots to get outside and enjoy nature. Playa Las Comadres and Playa El Rompio are a couple of places you'll find in the larger area.

What are vacation rentals like in Santo Domingo?

Vacation rentals are privately owned accommodations you can book for a couple days or more in Santo Domingo. Vacation rentals offer extras such as laundry facilities and kitchens so you'll feel right at home. If you're concerned about a clean environment, a vacation rental can provide a sense of security away from public hotel elevators and busy concierge desks while still allowing you the enjoyment of travel. You'll also find more space in a vacation rental than in a traditional hotel, which is another reason why a vacation rental is an attractive choice for family trips or small group gatherings.