Santo Domingo Vacations from $894

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Your Santo Domingo Vacation

Memorable adventures await when you book a Santo Domingo vacation package. Whether you're a foodie, history enthusiast or just a traveler who loves discovering new places, there's something for everyone in this interesting city. If your trip to Santo Domingo includes some sightseeing, don't miss well-known attractions like El Uverito Beach, Belisario Porras Park and Playa Las Comadres. That dream Santo Domingo vacation is just clicks away. Browse flights, hotels and more on Expedia for a getaway that's tailored to suit your travel style.

The Latest Santo Domingo vacation packages

Price found within the past 48 hours. Click for updated prices.
Decapolis Hotel Panama City

Decapolis Hotel Panama City

San Francisco
Save 100% on your flight
$894
per person
Sep 30 - Oct 7
found 1 day ago
Roundtrip flight included
Bridgetown (BGI) to Panama City (PTY)
8.6/10 Excellent! (1,716 reviews)
The property is excellent the fact that it’s connected to the mall and casino put it over the top. The staff are polite and always ready to assist you. Will definitely stay again.

Reviewed on Aug 28, 2026

Central Hotel Panama Casco Viejo

Central Hotel Panama Casco Viejo

Casco Viejo
Save 100% on your flight
$1,035
per person
Sep 30 - Oct 7
found 1 day ago
Roundtrip flight included
Bridgetown (BGI) to Panama City (PTY)
9.2/10 Wonderful! (1,005 reviews)
Breakfast is superb, a must have. Attentive staff, perfect location. Rooms facing main square can receive street noise but dies down by 11pm (but you get the best view)

Reviewed on Aug 28, 2026

Megapolis Hotel Panamá

Megapolis Hotel Panamá

San Francisco
Save 100% on your flight
$1,031
per person
Oct 3 - Oct 9
found 1 day ago
Roundtrip flight included
Bridgetown (BGI) to Panama City (PTY)
8.4/10 Very Good! (1,671 reviews)
El agua caliente no funcionaba me cambiaron de habitación y no funcionaba el control del TV y no hubo quien lo arreglara

Reviewed on Aug 28, 2026

Riande Aeropuerto Hotel & Casino

Riande Aeropuerto Hotel & Casino

$932
per person
Nov 7 - Nov 14
found 1 day ago
Roundtrip flight included
Bridgetown (BGI) to Panama City (PTY)
8.4/10 Very Good! (1,815 reviews)
We arrived early and paid $45 for early check-in. We were told it would be accommodated and asked to wait 10 minutes. After waiting closer to 30, we went back to the front desk, only to find our room key was already there and ready. No one had let us know. The room had a weird musky smell and, strangely, parts of the walls were lined with galvanized zinc. The AC also started leaking. We reported it and were told someone would check it and, if it couldn’t be fixed, we’d be moved. No one ever came. Thankfully, it eventually stopped on its own. We also initially thought there was no hot water until we realized the taps were reversed (H ran cold and C ran hot). On the plus side, the gardens and pool are really nice and well maintained, although the hot tub doesn’t actually have hot water. The pool bar was also closed despite advertised hours of 11am–10pm. We ordered a margherita pizza and got what was essentially a cheese pizza with a small tub of pesto on the side. Despite the quirks, we both got some much-needed sleep, and the location is very convenient for the airport. Overall, though, at $210 for one night plus $45 for early check-in, I’m not sure we got value for money. Traveller tip: For the airport shuttle, wait 10–15 mins past the scheduled time when arriving. When leaving, get downstairs 10–15 mins early or you may have to wait for the next shuttle or Uber.

Reviewed on Aug 28, 2026

Hotel Riu Plaza Panama

Hotel Riu Plaza Panama

Bella Vista
$1,016
per person
Nov 7 - Nov 14
found 1 day ago
Roundtrip flight included
Bridgetown (BGI) to Panama City (PTY)
9/10 Wonderful! (5,828 reviews)
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Stay near popular Santo Domingo attractions

Cerro La Teta

7.6/10 (5 reviews)
Find out about the history of Santo Domingo when you spend time at Cerro La Teta. Wander the beaches and seaside while you're in the area.
See properties

Santo Domingo Hotel Deals

Hotel Faranda Guayacanes, a member of Radisson Individuals

Hotel Faranda Guayacanes, a member of Radisson Individuals

Via Circunvalacion S/n Chitre Herrera
Fully refundableReserve now, pay when you stay
$69 nightly
$74 total
Sep 9 - Sep 10
Total with taxes and fees
8/10 Very Good! (349 reviews)
"Habitación muy bien, cama acogedora, las almohadas un sueño. Desayuno completo, variado y sufiente. Parking disponibles. Lo único es el restaurante, se demoran demasiado por atenderte (y estaba vacío) y así mismo se demoró en llevarte los alimentos."

Reviewed on Aug 22, 2026

Hotel Faranda Guayacanes, a member of Radisson Individuals
Casa Magna Panama

Casa Magna Panama

Agustin Cano Castillero Las Tablas Provincia de Los Santos
$55 nightly
$60 total
Sep 29 - Sep 30
Total with taxes and fees
9.8/10 Exceptional! (10 reviews)
"Everything was great, and my family will surely stay there again when we visit Las Tablas. After staying in many hotels in town over the years, Magna has to be the best hotel at a competitive price. Being overly critical, the bathroom sink and shower needed towels to help soak up some water leaks. ..."

Reviewed on Aug 9, 2026

Casa Magna Panama
Casa Lajagua

Casa Lajagua

Calle principal de Pedasi Pedasí Panama
$85 nightly
$94 total
Sep 8 - Sep 9
Total with taxes and fees
9.2/10 Wonderful! (92 reviews)
"A wonderful stay in a very convenient location. Looking forward to a return visit ."

Reviewed on Jun 24, 2026

Casa Lajagua
See all 71 properties in Santo Domingo
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find the Best Santo Domingo Vacation Packages

Santo Domingo Essential Information

Language
Spanish
Currency
Panamanian balboas
Local Welcome
¡Hola!
Local Goodbye
Adiós
Closest Airport
Chitre (CTD-Alonso Valderrama)
Population
1,750
Top Sights
El Uverito Beach, Playa Las Comadres and Refugio de Vida Silvestre Isla Iguana

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Frequently asked questions

How much does a Santo Domingo vacation package cost?
Offering great value package deals from $894 on Expedia, you'll be pleasantly surprised at how much a vacation to Santo Domingo costs! Expedia's packages make travel planning easier and save you more.
What are the cheapest months to go to Santo Domingo?
If you're hoping to book a cheap Santo Domingo vacation package, consider planning a trip in June, July and December. You'll usually find lower prices on flights and hotels during these quieter months — perfect for a budget-friendly getaway.
How many days is enough for Santo Domingo?
Generally, a handful of days is enough to see the major sights during your Santo Domingo vacation. However, if you want to have time to kick back or take day trips, think about extending your itinerary.
How to find the best Santo Domingo package deals?
Finding a cheap Santo Domingo package deal is a cinch with Expedia. Once you've entered your destination and travel dates under our "Packages" tab, set your budget range, add some filters and see what's available. You can tailor your search by "Amenities," "Property type," "Popular locations" and more. Sort the results by "Price: low to high" to view the most economical Santo Domingo package deals. Want a simple trick to score the biggest savings? Have some flexibility with your departure dates and consider traveling on a weekday, when prices are usually lower.
Is it cheaper to book a Santo Domingo vacation as a package?
An Expedia vacation package could land you considerable savings when compared to booking hotels and flights individually. Better still, you can customize your Santo Domingo getaway to fit your exact needs. Pick your preferred flight time, select the hotel type and add a car rental. Check out our great deals to see how much you can save.
When to book a vacation package to Santo Domingo?
Land incredible bargains by reserving your flights ahead of time with Expedia. If spontaneity is more your style, take advantage of our last-minute deals for an impromptu Santo Domingo getaway.
Does Expedia offer Book Now, Pay Later Santo Domingo vacation packages?
Secure your dream escape to Santo Domingo with help from Expedia's Book Now, Pay Later vacations. No need to save up or wait until the next payday — we've joined forces with online lender Affirm to give you flexibility with your finances. Our vacation packages with payment plans mean you can spread the cost over 3, 6 or 12 months. With no late payment fees or extra charges, you can easily stick to your budget and snap up cheap deals while they last.

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* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.