Santo Domingo Vacations from $861
Book a Hotel + Flight or Car together to unlock savings
- Plan, book, travel with confidence
- Better togetherSave up to $2,000 when you book a flight and hotel together*
- Find the right fitWith over 300,000 hotels worldwide, it's easy to create a perfect package
- Rest easyPlan, book, and manage your trip all in one place
Your Santo Domingo Vacation
Memorable adventures await when you book a Santo Domingo vacation package. Whether you're a foodie, history enthusiast or just a traveler who loves discovering new places, there's something for everyone in this interesting city. If your trip to Santo Domingo includes some sightseeing, don't miss well-known attractions like El Uverito Beach, Belisario Porras Park and Playa Las Comadres. That dream Santo Domingo vacation is just clicks away. Browse flights, hotels and more on Expedia for a getaway that's tailored to suit your travel style.
The Latest Santo Domingo vacation packages
Price found within the past 48 hours. Click for updated prices.
Riande Aeropuerto Hotel & Casino
Tocumen Airport
$865
per person
Nov 25 - Dec 2
found 1 day ago
Roundtrip flight included
Bridgetown (BGI) to Panama City (PTY)
8.6/10 Excellent! (1,811 reviews)
The hotel room didn’t have an iron and ironing board. There was no coffee maker or kettle, these are essentials and expected as a minimum. The name of the hotel includes a casino but there is none on property.
Apart from that all else went well.
Reviewed on Sep 14, 2026
Don't see what you're looking for?
See all available trips from Columbus to Santo Domingo
View all tripsStay near popular Santo Domingo attractions
Cerro La Teta
7.6/10 (5 reviews)
Find out about the history of Santo Domingo when you spend time at Cerro La Teta. Wander the beaches and seaside while you're in the area.
Santo Domingo Hotel Deals
Hotel Faranda Guayacanes, a member of Radisson Individuals
Via Circunvalacion S/n Chitre Herrera
Fully refundableReserve now, pay when you stay
$79 nightly
$87 total
Sep 17 - Sep 18
Total with taxes and fees
8/10 Very Good! (353 reviews)
"Muy bonito el hotel, ese detalle entre la naturaleza muy bueno, el puente en el estanque les encantó a mis hijos. El desayuno incluido de primera y la atención excelente!"
Reviewed on Sep 14, 2026
Casa Lajagua
Calle principal de Pedasi Pedasí Panama
$85 nightly
$94 total
Sep 17 - Sep 18
Total with taxes and fees
9.2/10 Wonderful! (93 reviews)
"Room was very clean and spacious. Lots of room in the showers, though controlling the temp was a little challenging. Beto (owner) was very nice, hospitable, and helpful. Lots of fruit trees on property along with 3 friendly pups. Breakfast was fantastic. Best we had in Panama. When arriving, you ..."
Reviewed on Sep 12, 2026
Hotel Presidente
Calle Moises Espino Las Tablas
$80 nightly
$88 total
Sep 17 - Sep 18
Total with taxes and fees
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Find the Best Santo Domingo Vacation Packages
Santo Domingo Essential Information
Language | Spanish |
|---|---|
Currency | Panamanian balboas |
Local Welcome | ¡Hola! |
Local Goodbye | Adiós |
Closest Airport | Chitre (CTD-Alonso Valderrama) |
Population | 1,750 |
Top Sights | El Uverito Beach, Playa Las Comadres and Refugio de Vida Silvestre Isla Iguana |
More vacations you might like
Frequently asked questions
How much does a Santo Domingo vacation package cost?
Offering great value package deals from $861 on Expedia, you'll be pleasantly surprised at how much a vacation to Santo Domingo costs! Expedia's packages make travel planning easier and save you more.
What are the cheapest months to go to Santo Domingo?
If you're hoping to book a cheap Santo Domingo vacation package, consider planning a trip in June, July and December. You'll usually find lower prices on flights and hotels during these quieter months — perfect for a budget-friendly getaway.
How many days is enough for Santo Domingo?
Generally, a handful of days is enough to see the major sights during your Santo Domingo vacation. However, if you want to have time to kick back or take day trips, think about extending your itinerary.
How to find the best Santo Domingo package deals?
Finding a cheap Santo Domingo package deal is a cinch with Expedia. Once you've entered your destination and travel dates under our "Packages" tab, set your budget range, add some filters and see what's available. You can tailor your search by "Amenities," "Property type," "Popular locations" and more. Sort the results by "Price: low to high" to view the most economical Santo Domingo package deals. Want a simple trick to score the biggest savings? Have some flexibility with your departure dates and consider traveling on a weekday, when prices are usually lower.
Is it cheaper to book a Santo Domingo vacation as a package?
An Expedia vacation package could land you considerable savings when compared to booking hotels and flights individually. Better still, you can customize your Santo Domingo getaway to fit your exact needs. Pick your preferred flight time, select the hotel type and add a car rental. Check out our great deals to see how much you can save.
When to book a vacation package to Santo Domingo?
Land incredible bargains by reserving your flights ahead of time with Expedia. If spontaneity is more your style, take advantage of our last-minute deals for an impromptu Santo Domingo getaway.
Does Expedia offer Book Now, Pay Later Santo Domingo vacation packages?
Secure your dream escape to Santo Domingo with help from Expedia's Book Now, Pay Later vacations. No need to save up or wait until the next payday — we've joined forces with online lender Affirm to give you flexibility with your finances. Our vacation packages with payment plans mean you can spread the cost over 3, 6 or 12 months. With no late payment fees or extra charges, you can easily stick to your budget and snap up cheap deals while they last.
Explore a world of travel with Expedia
- Pool in Las Tablas
- Bar in Las Tablas
- Hotels in Pocrí
- Apartments in Guarare
- 5 Star Hotels in Guarare
- 2 Star Hotels in Pocrí
- Romantic in Las Tablas
- Family Friendly in Las Tablas
- Dining in Las Tablas
- 5 Star Hotels in Las Tablas
- Bedandbreakfast in Las Tablas
- Apartments in Las Tablas
- Beach in Las Tablas
- Hostels in Guarare
- Budget in Las Tablas
- Hotels in Las Tablas
- Hotels in Santo Domingo
- Pet Friendly in Las Tablas
- Privatevacationhomes in Las Tablas
- 3 Star Hotels in Pocrí
- Independent Hotels in Guarare
- Resorts in Guarare
- Hotels in Guarare
- Independent Hotels in Pocrí
- 3 Star Hotels in Guarare
- Hotels in La Palma
- 2 Star Hotels in Las Tablas
- 5 Star Hotels in Santo Domingo
- Hostels in Las Tablas
- Dollar Rent A Car Rental Cars in Las Tablas
- Avis Rental Cars in Las Tablas
- Enterprise Rental Cars in Las Tablas
- Right-Cars Rental Cars in Las Tablas
- Auto Rent Rental Cars in Las Tablas
- Car rentals in La Palma
- Car rentals in Guarare
- Car rentals in Las Tablas
- Discount Quebec Rental Cars in Las Tablas
- Budget Israel Rental Cars in Las Tablas
- Hertz Rental Cars in Las Tablas
- Discount Car Rentals Rental Cars in Las Tablas
- Goldcar Rental Cars in Las Tablas
- Unidas Rental Cars in Las Tablas
- Drive on Holidays Rental Cars in Las Tablas
- Get Your Car Rental Cars in Las Tablas
- Hawk Rental Cars in Las Tablas
- Whiz Rental Cars in Las Tablas
- Europcar Rental Cars in Las Tablas
- Drive Car Rental Cars in Las Tablas
- Firefly EU Rental Cars in Las Tablas
- Thrifty Car Rental Cars in Las Tablas
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.
