Santo Domingo Vacations from $512

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Your Santo Domingo Vacation

Memorable adventures await when you book a Santo Domingo vacation package. Whether you're a foodie, history enthusiast or just a traveler who loves discovering new places, there's something for everyone in this interesting city. If your trip to Santo Domingo includes some sightseeing, don't miss well-known attractions like El Uverito Beach, Belisario Porras Park and Playa Las Comadres. That dream Santo Domingo vacation is just clicks away. Browse flights, hotels and more on Expedia for a getaway that's tailored to suit your travel style.

The Latest Santo Domingo vacation packages

Price found within the past 48 hours. Click for updated prices.
Nowhere

Nowhere

3 out of 5
Save 100% on your flight
Price was $868, price is now $512 per person
$512
per person
Feb 4 - Feb 10
found 1 day ago
Roundtrip flight included
Miami (MIA) to Panama City (PTY)
9.2/10 Wonderful! (17 reviews)
Room was spotless and grounds were well maintained. It was a perfect little oasis in the jungle!

Reviewed on Nov 13, 2025

Central Hotel Panama Casco Viejo

Central Hotel Panama Casco Viejo

4 out of 5
Casco Viejo
Price was $2,512, price is now $1,074 per person
$1,074
per person
Jan 30 - Feb 6
found 1 day ago
Roundtrip flight included
Bridgetown (BGI) to Panama City (PTY)
9/10 Wonderful! (1,005 reviews)
Staffs were wonderful.

Reviewed on Oct 28, 2025

Central Hotel Bocas del Toro

Central Hotel Bocas del Toro

3 out of 5
Price was $3,084, price is now $1,381 per person
$1,381
per person
Feb 4 - Feb 10
found 1 day ago
Roundtrip flight included
Miami (MIA) to Panama City (PTY)
No reviews
Punta Caracol Acqua Lodge

Punta Caracol Acqua Lodge

3.5 out of 5
Punta Caracol
Save 100% on your flight
Price was $1,484, price is now $830 per person
$830
per person
Feb 4 - Feb 10
found 1 day ago
Roundtrip flight included
Miami (MIA) to Panama City (PTY)
8.8/10 Excellent! (149 reviews)
Loved this property, and will definitely return!

Reviewed on Aug 14, 2025

La Coralina Island House

La Coralina Island House

3.5 out of 5
Save 100% on your flight
Price was $2,147, price is now $1,327 per person
$1,327
per person
Feb 4 - Feb 10
found 1 day ago
Roundtrip flight included
Miami (MIA) to Panama City (PTY)
9.4/10 Exceptional! (91 reviews)
Everything was great , lovely and peaceful place.

Reviewed on Sep 29, 2025

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Discover the most popular places to visit in Santo Domingo

Cerro La Teta

4/5(1 review)

Find out about the history of Santo Domingo when you spend time at Cerro La Teta. Wander the beaches and seaside while you're in the area.

Cerro La Teta

Santo Domingo Hotel Deals

Hotel Faranda Guayacanes, a member of Radisson Individuals

Hotel Faranda Guayacanes, a member of Radisson Individuals

3 out of 5
Via Circunvalacion S/n, Chitre, Herrera
Fully refundable
$83 nightly
The price is $91 total per night from Dec 14 to Dec 15
$91 total
Dec 14 - Dec 15
Total with taxes and fees
7.8/10 Good! (282 reviews)
Rooms spotless & comfortable, great breakfast included though property is over rated especially the pool area 👍

Reviewed on Nov 5, 2025

Hotel Faranda Guayacanes, a member of Radisson Individuals
Casa Lajagua

Casa Lajagua

3 out of 5
Calle principal de Pedasi, Pedasí, Panama
$85 nightly
The price is $94 total per night from Nov 19 to Nov 20
$94 total
Nov 19 - Nov 20
Total with taxes and fees
9/10 Wonderful! (83 reviews)
Good value for cost. Clean, basic but comfortable rooms. Nice hot breakfast. Feel is more like B&B than Hotel, common areas feel real homey, quiet and safe little town in great location. great for an overnight

Reviewed on Sep 24, 2025

Casa Lajagua
Hotel Presidente

Hotel Presidente

3.5 out of 5
Calle Moises Espino, y Calle Pablo Arosemena, Las Tablas
$80 nightly
The price is $88 total per night from Nov 15 to Nov 16
$88 total
Nov 15 - Nov 16
Total with taxes and fees
9/10 Wonderful! (108 reviews)
Outstanding hotel!!! Excellent service!!! Great food!!!

Reviewed on Sep 21, 2025

Hotel Presidente
See all 57 properties in Santo Domingo
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find the Best Santo Domingo Vacation Packages

Santo Domingo Essential Information

Language
Spanish
Currency
Panamanian balboas
Local Welcome
¡Hola!
Local Goodbye
Adiós
Closest Airport
Chitre (CTD-Alonso Valderrama)
Population
1,750
Top Sights
El Uverito Beach, Playa Las Comadres and Refugio de Vida Silvestre Isla Iguana

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Frequently asked questions

How much does a Santo Domingo vacation package cost?
Offering great value package deals from $512 on Expedia, you'll be pleasantly surprised at how much a vacation to Santo Domingo costs! Expedia's packages make travel planning easier and save you more.
What are the cheapest months to go to Santo Domingo?
If you're hoping to book a cheap Santo Domingo vacation package, consider planning a trip in June, July and December. You'll usually find lower prices on flights and hotels during these quieter months — perfect for a budget-friendly getaway.
How many days is enough for Santo Domingo?
Generally, a handful of days is enough to see the major sights during your Santo Domingo vacation. However, if you want to have time to kick back or take day trips, think about extending your itinerary.
How to find the best Santo Domingo package deals?
Finding a cheap Santo Domingo package deal is a cinch with Expedia. Once you've entered your destination and travel dates under our "Packages" tab, set your budget range, add some filters and see what's available. You can tailor your search by "Amenities," "Property type," "Popular locations" and more. Sort the results by "Price: low to high" to view the most economical Santo Domingo package deals. Want a simple trick to score the biggest savings? Have some flexibility with your departure dates and consider traveling on a weekday, when prices are usually lower.
Is it cheaper to book a Santo Domingo vacation as a package?
An Expedia vacation package could land you considerable savings when compared to booking hotels and flights individually. Better still, you can customize your Santo Domingo getaway to fit your exact needs. Pick your preferred flight time, select the hotel type and add a car rental. Check out our great deals to see how much you can save.
When to book a vacation package to Santo Domingo?
Land incredible bargains by reserving your flights ahead of time with Expedia. If spontaneity is more your style, take advantage of our last-minute deals for an impromptu Santo Domingo getaway.
Does Expedia offer Book Now, Pay Later Santo Domingo vacation packages?
Secure your dream escape to Santo Domingo with help from Expedia's Book Now, Pay Later vacations. No need to save up or wait until the next payday — we've joined forces with online lender Affirm to give you flexibility with your finances. Our vacation packages with payment plans mean you can spread the cost over 3, 6 or 12 months. With no late payment fees or extra charges, you can easily stick to your budget and snap up cheap deals while they last.

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* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.