Santo Domingo

Travel Guide

Hotel Faranda Guayacanes, a member of Radisson Individuals

Hotel Faranda Guayacanes, a member of Radisson Individuals

3 out of 5
Via Circunvalacion S/n Chitre Herrera
$77 nightly
The price is $84 total per night from Oct 1 to Oct 2
$84 total
Oct 1 - Oct 2
Total with taxes and fees
Book a stay at this family-friendly hotel in Chitre. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular ...
8/10 Very Good! (358 reviews)
"en la habitación, cre deben poaner más atención en los baños, como colocar la toalla del piso al salir de la ducha, colocar toalla para las manos, si saben cuantas personas están en la habitación, colocar la cantidad correcta de toallas, no había Klinnex, son detalles básicos de cualquier hotel, ..."

Reviewed on Sep 29, 2026

Hotel Faranda Guayacanes, a member of Radisson Individuals
Casa Lajagua

Casa Lajagua

3 out of 5
Calle principal de Pedasi Pedasí Panama
$85 nightly
The price is $94 total per night from Oct 1 to Oct 2
$94 total
Oct 1 - Oct 2
Total with taxes and fees
Stay at this B&B in Pedasí. Enjoy free breakfast, free parking, and an outdoor pool. Popular attractions Playa El Arenal and Playa El Toro are located ...
9.2/10 Wonderful! (93 reviews)
"Room was very clean and spacious. Lots of room in the showers, though controlling the temp was a little challenging. Beto (owner) was very nice, hospitable, and helpful. Lots of fruit trees on property along with 3 friendly pups. Breakfast was fantastic. Best we had in Panama. When arriving, you ..."

Reviewed on Sep 12, 2026

Casa Lajagua
Alaya Panama – Private Retreat & Wellness Resort

Alaya Panama – Private Retreat & Wellness Resort

4 out of 5
Venao Canas Los Santos
$272 nightly
The price is $299 total per night from Oct 1 to Oct 2
$299 total
Oct 1 - Oct 2
Total with taxes and fees
Stay at this hotel in Canas. Enjoy free breakfast, free WiFi, and free parking. Popular attraction Venao Beach is located nearby.
9.4/10 Exceptional! (18 reviews)
"Fantastic place to stay. Everything was premium. Bed was spectacular left after two years feeling super replaced. Would recommend highly."

Reviewed on Feb 10, 2026

Alaya Panama – Private Retreat & Wellness Resort
See all 71 properties in Santo Domingo
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
DRONES PEDASI RANCH - BEACHFRONT, POOL, 3BRM - 5BATH + Whales Watching & Fishing

DRONES PEDASI RANCH - BEACHFRONT, POOL, 3BRM - 5BATH + Whales Watching & Fishing

Pedasi Los Santos
Book a stay at this beach villa in Pedasí. Enjoy free WiFi, a beach locale, and breakfast (surcharge). Popular attractions Playa El Toro and Playa El Arenal ...
9/10 Wonderful! (4 reviews)
"Welcoming host, great location, quick response to questions."

Reviewed on Mar 1, 2026

DRONES PEDASI RANCH - BEACHFRONT, POOL, 3BRM - 5BATH + Whales Watching & Fishing
1st Floor Beach House Apartment just steps from the beach!

1st Floor Beach House Apartment just steps from the beach!

Las Tablas Los Santos
Stay at this apartment in Las Tablas. Enjoy free WiFi, a garden, and laundry facilities. Popular attractions El Uverito Beach and Cerro La Teta are located ...
9.6/10 Exceptional! (7 reviews)
"Beautiful location. Fully stocked kitchen with all the dishes and utensils one could every need. Comfortable bed and pillows. The host is very responsive. The unit is as advertised. My husband and I had a wonderful stay. Absolutely recommend."

Reviewed on May 30, 2026

1st Floor Beach House Apartment just steps from the beach!
La Placita - Apartamentos

La Placita - Apartamentos

2 out of 5
Agustin Cano Castillero Las Tablas Provincia de Los Santos
Stay at this apartment in Las Tablas. Popular attractions Museo Belisario Porras and Iglesia Santa Librada are located nearby.
8.4/10 Very Good! (5 reviews)
"Muy lindo el lugar y céntrico"

Reviewed on Sep 26, 2026

La Placita - Apartamentos
See all properties in Santo Domingo
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Stay near popular Santo Domingo attractions

Cerro La Teta

7.6/10 (5 reviews)
Find out about the history of Santo Domingo when you spend time at Cerro La Teta. Wander the beaches and seaside while you're in the area.
See properties

Frequently asked questions

Is Santo Domingo worth visiting?
Santo Domingo is worth visiting for its unique natural attractions, such as Cerro La Teta, which offers travelers scenic experiences. The destination also features a flavorful culinary scene, with diverse options ranging from Latin American specialties to classic Italian dishes.
When is the best time to visit Santo Domingo?
The best time to visit Santo Domingo is from August through December, when the climate is generally pleasant for exploring. For travelers seeking fewer crowds and better value, the quieter months of February through May are a good option, offering a similarly enjoyable climate with a more relaxed atmosphere.
What is Santo Domingo known for?
Santo Domingo is known for Cerro La Teta, a prominent mountain that stands out in the landscape. This city in Panama also offers travelers a rich Latin American food culture, with many diverse culinary experiences to discover.
What is a good itinerary length for Santo Domingo?
A good itinerary length for Santo Domingo is one to two days to explore Cerro La Teta and enjoy the local Latin American, Italian, and Asian cuisine. An extended stay of three days allows for a more relaxed pace and deeper enjoyment of the area.
What are the top things to do in and around Santo Domingo?
In Santo Domingo, travelers can explore Cerro La Teta, a natural point of interest.
What cuisines can you find in Santo Domingo?
In Santo Domingo, you can find Caribbean cuisine, with dishes like sancocho, mangú, and fried plantains. Travelers can also enjoy other Latin American flavors, including Mexican and South American options, as well as Italian, Asian, and European dishes, and a variety of fresh seafood.
Can I book a refundable hotel in Santo Domingo?
Yes, Expedia offers many flexible booking options, and you can look for refundable hotels in Santo Domingo by entering your dates and using the refundable or fully refundable filter. Always check the hotel's cancellation policy before you book, since terms can vary by hotel, and visit Expedia help center for further details.
Why book a trip to Santo Domingo with Expedia?
Expedia makes it easier to plan your Santo Domingo trip with travel tools, flexible search options, and bookable trip components all in one place. You can organize your plans in one account and use Expedia to help build a trip that fits your budget and travel style. Find out more about how by visiting Expedia's Trip Planner page.
Should I stay in a hotel or vacation rental in Santo Domingo?
The best choice depends on your travel style. Hotels in Santo Domingo can be a good fit for convenience, on-site amenities, and shorter stays, while vacation rentals may offer more space, privacy, and home-style amenities for longer trips, families, or groups. With Expedia, you can compare both options side by side, read traveler reviews, and filter by amenities to find the right fit for your trip.
How can I manage my Santo Domingo trip on Expedia?
Once you've booked your Santo Domingo trip, you can manage it through your Expedia account or the Expedia app. You can view your itinerary, access booking details, make eligible changes, and check for updates in My Trips. The Expedia app can also help you stay organized while you travel.
What if I need help during my Santo Domingo trip?
Expedia offers customer support before, during, and after your Santo Domingo trip. If your plans change or something unexpected happens, you can review your booking in My Trips and use Expedia help center channels for help with eligible changes, cancellations, or travel issues.
How can Expedia help me plan my first trip to Santo Domingo?
If it's your first trip to Santo Domingo, Expedia can help you plan by bringing together stays, flights, activities, traveler reviews, and trip-planning tools in one place. With Expedia's Trip Planner you can compare options, read reviews from other travelers, and build an itinerary that matches your interests and budget.
How can I save on my Santo Domingo hotel booking with Expedia?
Join One Key™ for free to unlock instant discounts with Member Prices on select hotels. You can also earn and use OneKeyCash™* on eligible bookings on Expedia. Booking in advance is usually another great way to save on your Santo Domingo hotel.

*Excludes taxes and fees. OneKeyCash is not redeemable for cash and can only be used on Expedia and other participating brands.

Cities near Santo Domingo

A sandy beach with clear turquoise water, two rocky outcrops, and a clear sky.

Las Tablas

Explore a world of travel with Expedia