Photo by Serendipity Trip

Find Business Hotels in Southeastern Indiana

Start date: Check-in selected.
To Date
End date: Check-out

Check availability on Southeastern Indiana Business Hotels

Tonight
Dec 7 - Dec 8
Tomorrow
Dec 8 - Dec 9
Next weekend
Dec 12 - Dec 14
In two weeks
Dec 19 - Dec 21

Top Southeastern Indiana Business Hotels

Exterior
Holiday Inn Express Corydon by IHG

Holiday Inn Express Corydon by IHG

2.5 star property
Corydon
8.6 out of 10, Excellent, (359)
"Very clean and great staff!"
United States
Donna
$90 nightly
The price is $100
Dec 14 - Dec 15
Total with taxes and fees
Holiday Inn Express Corydon by IHG
Exterior
Comfort Inn Madison near Clifty Falls

Comfort Inn Madison near Clifty Falls

2.5 star property
Madison
8.8 out of 10, Excellent, (660)
"Great stay, clean, and comfy bed!"
United States
cheryl
$93 nightly
The price is $107
Dec 14 - Dec 15
Total with taxes and fees
Comfort Inn Madison near Clifty Falls
2 restaurants, breakfast served
Tempo By Hilton Louisville Downtown Nulu

Tempo By Hilton Louisville Downtown Nulu

3.5 star property
Downtown Louisville
9.4 out of 10, Exceptional, (815)
"Love the hotel and will always stay there when visiting "
United States
Jeremy
$95 nightly
The price is $112
Dec 23 - Dec 24
Total with taxes and fees
Tempo By Hilton Louisville Downtown Nulu
Meeting facility
Fairfield Inn & Suites Madison Historic Eagle Cotton Mill

Fairfield Inn & Suites Madison Historic Eagle Cotton Mill

2.5 star property
Madison
9.8 out of 10, Exceptional, (392)
"Beautiful hotel, rooms were exceptionally clean, service was so friendly. Love this place and will return."
United States
Paul
$135 nightly
The price is $155
Jan 1 - Jan 2, 2026
Total with taxes and fees
Fairfield Inn & Suites Madison Historic Eagle Cotton Mill
Exterior
Belterra Casino Resort

Belterra Casino Resort

3.5 star property
Florence
8.6 out of 10, Excellent, (1002)
"Room was clean and the staff was good."
United States
Gary
$129 nightly
The price is $145
Dec 14 - Dec 15
Total with taxes and fees
Belterra Casino Resort
Free daily on-the-go breakfast
Hampton Inn Corydon

Hampton Inn Corydon

2.5 star property
Corydon
8.8 out of 10, Excellent, (600)
"Excellent place to stay"
United States
Tera
$103 nightly
The price is $115
Dec 11 - Dec 12
Total with taxes and fees
Hampton Inn Corydon
4 restaurants, breakfast, lunch, dinner served; American cuisine
Galt House Hotel Trademark Collection by Wyndham

Galt House Hotel Trademark Collection by Wyndham

4.0 star property
Downtown Louisville
9.0 out of 10, Wonderful, (3834)
"Beautiful room and great hospitality. "
United States
Chase
$133 nightly
The price is $157
Dec 16 - Dec 17
Total with taxes and fees
Galt House Hotel Trademark Collection by Wyndham
Property amenity
Hillside Inn

Hillside Inn

2.5 star property
Madison
8.6 out of 10, Excellent, (1002)
"Great view, friendly staff."
United States
Roy
$80 nightly
The price is $92
Jan 1 - Jan 2, 2026
Total with taxes and fees
Hillside Inn
Lobby
The Brown Hotel

The Brown Hotel

4.5 star property
Downtown Louisville
9.4 out of 10, Exceptional, (1145)
"I loved everything about this place"
United States
Steven
$168 nightly
The price is $198
Dec 21 - Dec 22
Total with taxes and fees
The Brown Hotel
Exterior
Hilton Garden Inn Jeffersonville Louisville North

Hilton Garden Inn Jeffersonville Louisville North

3.0 star property
Jeffersonville
9.6 out of 10, Exceptional, (399)
"The staff was very friendly and helpful. The facility was clean, safe and well maintained. "
United States
Bianca
$103 nightly
The price is $117
Dec 14 - Dec 15
Total with taxes and fees
Hilton Garden Inn Jeffersonville Louisville North
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Top Southeastern Indiana Hotel Reviews

Radisson Hotel Louisville North

Radisson Hotel Louisville North

10/10 Excellent
"Great, will book again !"
RaSean 2-night trip
Posted 1 day ago
Radisson Hotel Louisville North

Frequently asked questions

How much do business-friendly hotels in Southeastern Indiana cost?
You'll pay between $92 and $198 per night for business-friendly hotels in Southeastern Indiana. Epic deals on properties that cater to work-related travelers are only a click away on Expedia. These prices were available on Expedia within the past 7 days, for a hotel booking with a check-in date within the next year. Prices reflect current offers and availability is subject to change. Additional terms may apply.
What are the best business-friendly hotels in Southeastern Indiana?
That depends on where in Southeastern Indiana you're headed. Many business travelers to Louisville like to base themselves at Residence Inn by Marriott Louisville East/Oxmoor. This 3-stars property has designer toiletries and a terrace. Hilton Garden Inn Louisville Mall of St. Matthews is another in-demand option if you're attending a corporate event or working remotely in Louisville. A terrace and a firepit are among the handy amenities at this 3-stars retreat. You can choose from multiple business-friendly hotels in Southeastern Indiana that have a total average guest review rating of 8.9.
How many business-friendly hotels are there in Southeastern Indiana?
Choose from 69 business-friendly hotels in Southeastern Indiana. Wherever your job is taking you, Expedia can help you find the perfect space with the amenities you need.
What are the best cheap business-friendly hotels in Southeastern Indiana?
When work is taking you on the road in Southeastern Indiana, Expedia will help you find the ideal business-friendly hotel. Holiday Inn Express & Suites Louisville Downtown, an IHG Hotel is a popular budget option in Louisville. Hypo-allergenic bedding and an electric car charging station are among its many amenities. In search of inexpensive properties in Jeffersonville - Clarksville? TownePlace Suites by Marriott Louisville North is rated highly with corporate guests. It has conveniences that make it easy to both work and feel at home, such as a barbecue grill and a swimming pool. Business-friendly hotels in Southeastern Indiana start at just $92 a night. Mix business with leisure by visiting a few fabulously free attractions on your upcoming work trip in Southeastern Indiana. Louisville Waterfront Park in Louisville is one for your list. If you're headed to Jeffersonville - Clarksville, you won't have to spend a penny when visiting Louisville Waterfront Park. This price was available on Expedia within the past 7 days, for a hotel booking with a check-in date within the next year. Prices reflect current offers and availability is subject to change. Additional terms may apply.
What are the top business-friendly motels in Southeastern Indiana?
Cost-effective and comfortable, motels are a great choice for your next business trip in Southeastern Indiana. If an event or a meeting is taking you to Louisville, check out the availability at Days Inn by Wyndham Louisville Airport Fair and Expo Center. It's around 7 miles south of downtown and features amenities such as individually decorated rooms and blackout curtains. Super 8 by Wyndham Louisville Airport also welcomes corporate guests. It has blackout curtains and WiFi and is located about 6 miles south of the center of Louisville.Louisville offers all manner of fantastic attractions to keep you entertained. Be sure to stop by Louisville Slugger Museum and Kentucky Kingdom during your free time.
Are there any family-friendly hotels in Southeastern Indiana that are also business friendly?
If you're traveling for business in Southeastern Indiana and bringing your family along for the ride, Expedia is here to help you find a cozy and convenient stay. Residence Inn by Marriott Louisville East/Oxmoor in Louisville is the perfect option for those combining work and leisure. This 3-stars property offers all the necessary amenities, like complimentary breakfast and laundry facilities. Hilton Garden Inn Louisville Mall of St. Matthews is another fantastic choice in Louisville. You'll be able to combine corporate travel and quality time with your family at this 3-stars property. Laundry facilities and WiFi are among the conveniences here. Louisville has lots of family-friendly attractions when you're ready to tour the sights. Louisville Slugger Museum and Kentucky Kingdom promise fun for everyone.
Are there any 5-star business-friendly hotels in Southeastern Indiana?
In Southeastern Indiana, 5-star business-friendly hotels are hard to come by. However, there are some 4-star options that are ideal for corporate travelers. If you're making tracks to Louisville for work, base yourself at Hotel Distil, Autograph Collection. It comes with handy amenities including pillow top mattresses and a firepit. Or, kick back after a busy day of meetings at Omni Louisville Hotel, also in Louisville. Make the most of its conveniences including a terrace and spa facilities.
Why book your business-friendly hotel in Southeastern Indiana with Expedia?
With top amenities like meeting rooms, housekeeping and on-site restaurants, our business-friendly properties come with everything you'll need to complete the job — and then relax in the comfort of your room. Enter your travel destination and preferred dates and Expedia will help you do the rest.
How can I find cheap business-friendly hotels in Southeastern Indiana?
When you're traveling for work in Southeastern Indiana, our "business friendly" filter will help you find the ideal hotel. From included breakfast and free WiFi to conference spaces and in-room desks, they have the amenities you need to get the job done. You can also narrow your search by your preferred star rating and budget to see the cheapest properties.
What is there to do in Southeastern Indiana near my business-friendly hotel?
One of the best travel accessories for your Southeastern Indiana business journey is an awesome itinerary for when you have time to spare! Louisville Slugger Museum, Louisville Waterfront Park and Louisville Palace are some of the leading sights if you're bound for Louisville. Jeffersonville - Clarksville also offers many fantastic attractions, such as Louisville Slugger Museum, Louisville Waterfront Park and Muhammad Ali Center.