
Southeastern Indiana Vacations from $394
Book a Hotel + Flight or Car together to unlock savings
- Plan, book, travel with confidence
- Better togetherSave up to $1,045 when you book a flight and hotel together*
- Find the right fitWith over 300,000 hotels worldwide, it's easy to create a perfect package
- Rest easyPlan, book, and manage your trip all in one place
Your Southeastern Indiana Vacation
Head off on your next big adventure with a Southeastern Indiana vacation package, and leave knowing all the details are organized. And with the ability to customize your getaway, you know it'll be one to remember. Your trip to Southeastern Indiana wouldn't be complete without getting to some of its most well-known cities, starting with Louisville. A couple of the top attractions here include KFC Yum Center and Kentucky Kingdom. Radcliff should also be on the itineraries of all Southeastern Indiana travelers. Visitors to this exciting city love Freeman Lake Park and General George Patton Museum. Whether you're planning to travel for a few days or a few weeks, Expedia are here to help you tailor-make your next dream Southeastern Indiana vacation.
The Latest Southeastern Indiana vacation packages

Radisson Hotel Cincinnati Riverfront
Reviewed on Apr 11, 2026

Hotel Covington Cincinnati Riverfront
Reviewed on Apr 3, 2026

Embassy Suites by Hilton Cincinnati RiverCenter
Reviewed on Apr 11, 2026

Holiday Inn Express & Suites Cincinnati Riverfront by IHG
Reviewed on Apr 5, 2026

Belterra Casino Resort
Reviewed on Apr 7, 2026
Where to stay in Southeastern Indiana

West Main Historic District
Boasting the largest collection of cast iron façades outside New York's SoHo district, this historic area features "Museum Row" with attractions like the Louisville Slugger Museum and Muhammad Ali Center.
Discover the most popular places to visit in Southeastern Indiana

KFC Yum Center
Catch an event at KFC Yum Center during your trip to Louisville. Stroll along the riverfront or attend a sporting event in the area.

Louisville Slugger Museum
Baseball is part of the American fabric. See where one important tool for this sport is produced in the factory that makes ball games possible.

Whiskey Row
Find out about the history of Louisville when you spend time at Whiskey Row. Attend a sporting event or simply enjoy the lively bars while you're in the area.
Southeastern Indiana Hotel Deals

Radisson Hotel Louisville North
Yes
Reviewed on Apr 10, 2026

Derby Hotel & Suites
Yes us and the kids loved the pool area and had a blast on our trip.
Reviewed on Mar 31, 2026

Motel 6 Jeffersonville, In - Louisville
While staff were respectful, the desk manager absolutely refused to budge on a deposit fee. I understand that they have policies, but the entire conversation was purely transactional, not customer oriented. I had forgotten about the deposit fee and had spent essentially my last dollar to bring my ...
Reviewed on Apr 6, 2026
Find the Best Southeastern Indiana Vacation Packages
Southeastern Indiana Essential Information
Language | English |
|---|---|
Currency | U.S dollars |
Closest Airport | O'Hare Intl. Airport (ORD) |






















