
Southeastern Indiana Vacations from $398
Book a Hotel + Flight or Car together to unlock savings
- Plan, book, travel with confidence
Better together
Find the right fit
Rest easy
Your Southeastern Indiana Vacation
Head off on your next big adventure with a Southeastern Indiana vacation package, and leave knowing all the details are organized. And with the ability to customize your getaway, you know it'll be one to remember. Your trip to Southeastern Indiana wouldn't be complete without getting to some of its most well-known cities, starting with Louisville. A couple of the top attractions here include KFC Yum Center and Kentucky Kingdom. Radcliff should also be on the itineraries of all Southeastern Indiana travelers. Visitors to this exciting city love Freeman Lake Park and General George Patton Museum. Whether you're planning to travel for a few days or a few weeks, Expedia are here to help you tailor-make your next dream Southeastern Indiana vacation.
The Latest Southeastern Indiana vacation packages


Hilton Cincinnati Netherland Plaza
Reviewed on Aug 2, 2025

Caesars Southern Indiana
Reviewed on Jul 25, 2025

The Cincinnatian Hotel Curio Collection by Hilton
Reviewed on Aug 2, 2025

21c Museum Hotel Cincinnati
Reviewed on Jul 28, 2025
Where to stay in Southeastern Indiana

West Main Historic District
Boasting the largest collection of cast iron façades outside New York's SoHo district, this historic area features "Museum Row" with attractions like the Louisville Slugger Museum and Muhammad Ali Center.
Discover the most popular places to visit in Southeastern Indiana

Louisville Slugger Museum
Baseball is part of the American fabric. See where one important tool for this sport is produced in the factory that makes ball games possible.

Whiskey Row
Find out about the history of Louisville when you spend time at Whiskey Row. Attend a sporting event or simply enjoy the top-notch restaurants while you're in the area.

Louisville Waterfront Park
After visiting Louisville Waterfront Park, make a plan to see the other sights and activities in Louisville. Stroll along the area's riverfront or experience its great live music.
Southeastern Indiana Hotel Deals

Radisson Hotel Louisville North
Reviewed on Aug 1, 2025

Comfort Inn & Suites Clarksville - Louisville North
Reviewed on Aug 1, 2025

Sheraton Louisville Riverside by Marriott
Reviewed on Jul 15, 2025