Find hotels near UnityPoint Health St. Luke's, Sioux City from $51

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Compare 108 hotels close to UnityPoint Health St. Luke's with room rates, reviews, and availability. Most hotels are fully refundable.

The Warrior Hotel, Autograph Collection

5.0 star property
1.6 mi from UnityPoint Health St. Luke's
9.0 out of 10, Wonderful, (500)
"Wonderful hotel! We will stay again!"
United States
Amanda
$94 nightly
The price is $105
Dec 7 - Dec 8
Total with taxes and fees
The Warrior Hotel, Autograph Collection

Hard Rock Hotel & Casino Sioux City

4.0 star property
1.8 mi from UnityPoint Health St. Luke's
9.2 out of 10, Wonderful, (1000)
"Room was very clean, check in was great and staff was very friendly and helpful "
United States
Cheri
$139 nightly
The price is $156
Dec 4 - Dec 5
Total with taxes and fees
Hard Rock Hotel & Casino Sioux City

Stoney Creek Hotel Sioux City

2.5 star property
1.8 mi from UnityPoint Health St. Luke's
9.0 out of 10, Wonderful, (2389)
"Yess everything clean and staff fantastic "
United States
Leonardo
$85 nightly
The price is $95
Jan 1 - Jan 2, 2026
Total with taxes and fees
Stoney Creek Hotel Sioux City

Courtyard by Marriott Sioux City Downtown/Convention Center

3.0 star property
1.8 mi from UnityPoint Health St. Luke's
9.0 out of 10, Wonderful, (598)
"Excellent place to stay!!"
United States
Robert
$93 nightly
The price is $104
Dec 26 - Dec 27
Total with taxes and fees
Courtyard by Marriott Sioux City Downtown/Convention Center

DoubleTree by Hilton Sioux City

4.0 star property
2 mi from UnityPoint Health St. Luke's
9.4 out of 10, Exceptional, (120)
"Clean room and staff was great "
United States
timothy
$91 nightly
The price is $102
Dec 11 - Dec 12
Total with taxes and fees
DoubleTree by Hilton Sioux City

avid hotel Sioux City - Downtown by IHG

2.5 star property
2 mi from UnityPoint Health St. Luke's
8.6 out of 10, Excellent, (428)
"Staff at the front were very friendly. "
United States
Maria
$89 nightly
The price is $99
Dec 8 - Dec 9
Total with taxes and fees
avid hotel Sioux City - Downtown by IHG

Hilton Garden Inn Sioux City Riverfront

3.0 star property
2.2 mi from UnityPoint Health St. Luke's
8.8 out of 10, Excellent, (1000)
"Service at the desk and in the restaurant was excellent."
United States
Todd E
$89 nightly
The price is $99
Dec 26 - Dec 27
Total with taxes and fees
Hilton Garden Inn Sioux City Riverfront

South Sioux City Marriott Riverfront

3.0 star property
2.4 mi from UnityPoint Health St. Luke's
8.8 out of 10, Excellent, (1000)
"Clean hotel, updated rooms, comfortable beds and pillows. Beautiful location."
United States
Jenna
$101 nightly
The price is $113
Dec 13 - Dec 14
Total with taxes and fees
South Sioux City Marriott Riverfront

Super 8 by Wyndham Sioux City/Morningside Area

2.0 star property
3.9 mi from UnityPoint Health St. Luke's
6.2 out of 10, (834)
"Easy check in"
United States
Walter D.
$48 nightly
The price is $54
Dec 7 - Dec 8
Total with taxes and fees
Super 8 by Wyndham Sioux City/Morningside Area

Days Inn by Wyndham North Sioux City

2.0 star property
4.9 mi from UnityPoint Health St. Luke's
6.6 out of 10, (591)
"love this place my favorite place in town had a great price"
United States
Bryan
$47 nightly
The price is $51
Dec 7 - Dec 8
Total with taxes and fees
Days Inn by Wyndham North Sioux City

Motel 6 North Sioux City, SD – I-29 North

2.0 star property
4.9 mi from UnityPoint Health St. Luke's
6.4 out of 10, (365)
"Great room and pet friendly! Does not charge for pets!"
United States
Pam
$60 nightly
The price is $65
Dec 4 - Dec 5
Total with taxes and fees
Motel 6 North Sioux City, SD – I-29 North

Quality Inn & Suites Sioux City Southeast

2.5 star property
6.3 mi from UnityPoint Health St. Luke's
6.6 out of 10, (562)
"Especially liked the handicapped parking next to the front entrance!"
United States
Rachel
$67 nightly
The price is $75
Dec 7 - Dec 8
Total with taxes and fees
Quality Inn & Suites Sioux City Southeast

Rodeway Inn Sergeant Bluff - Sioux City

2.0 star property
8.6 mi from UnityPoint Health St. Luke's
5.8 out of 10, (205)
"I never was available to check in lobby door lock and mobile open the door I was ringing for over 45 minutes "
United States
Adalberto
$54 nightly
The price is $60
Dec 10 - Dec 11
Total with taxes and fees
Rodeway Inn Sergeant Bluff - Sioux City

Holiday Inn Express & Suites Sioux City North-Event Center by IHG

2.5 star property
4.4 mi from UnityPoint Health St. Luke's
9.4 out of 10, Exceptional, (749)
"Everything was excellent here really appreciated the property"
United States
Zeretta
$102 nightly
The price is $107
Dec 14 - Dec 15
Total with taxes and fees
Holiday Inn Express & Suites Sioux City North-Event Center by IHG

Country Inn & Suites by Radisson, Dakota Dunes, SD

3.0 star property
4.7 mi from UnityPoint Health St. Luke's
8.8 out of 10, Excellent, (1011)
"Fast check in, clean, decent coffee"
Canada
Robert
$89 nightly
The price is $93
Dec 26 - Dec 27
Total with taxes and fees
Country Inn & Suites by Radisson, Dakota Dunes, SD

Hampton Inn North Sioux City

2.5 star property
4.9 mi from UnityPoint Health St. Luke's
9.0 out of 10, Wonderful, (822)
"close to Interstate"
United States
Judith
$85 nightly
The price is $92
Dec 11 - Dec 12
Total with taxes and fees
Hampton Inn North Sioux City

Cottonwood Inn and Conference Center

2.5 star property
5.1 mi from UnityPoint Health St. Luke's
8.4 out of 10, Very Good, (1015)
"Great little area, cozy rooms."
Canada
Lynn
$63 nightly
The price is $71
Dec 9 - Dec 10
Total with taxes and fees
Cottonwood Inn and Conference Center

New Victorian Inn & Suites in Sioux City, IA

2.5 star property
6.1 mi from UnityPoint Health St. Luke's
8.8 out of 10, Excellent, (1013)
"Great place to stay. Will stay there again ."
United States
Elnora
$75 nightly
The price is $84
Dec 7 - Dec 8
Total with taxes and fees
New Victorian Inn & Suites in Sioux City, IA

Super 8 by Wyndham North Sioux City

2.0 star property
4.9 mi from UnityPoint Health St. Luke's
7.2 out of 10, Good, (624)
"it was good and breakfast serve on time.clean room."
United States
Estela
$52 nightly
The price is $57
Dec 5 - Dec 6
Total with taxes and fees
Super 8 by Wyndham North Sioux City

Hampton Inn & Suites Sioux City South

2.5 star property
6.2 mi from UnityPoint Health St. Luke's
9.2 out of 10, Wonderful, (997)
"It was a great stay"
United States
Jamie
$84 nightly
The price is $95
Dec 20 - Dec 21
Total with taxes and fees
Hampton Inn & Suites Sioux City South
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

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Frequently asked questions

What's the area like around UnityPoint Health St. Luke's?
UnityPoint Health St. Luke's is located in Sioux City. Travelers like this family-friendly area for its sporting events and live music. You'll find 61 hotels and other accommodations within a few miles for a convenient home base.
What's the best hotel to stay near UnityPoint Health St. Luke's?
Stoney Creek Hotel Sioux City is one of the top choices for your stay based on our traveler data, and this hotel offers free breakfast and an outdoor pool. It's located 1.8 mi (3 km) from UnityPoint Health St. Luke's. Other good choices within 5 miles include The Warrior Hotel, Autograph Collection and Hard Rock Hotel & Casino Sioux City.
How many hotels can I expect to find close to UnityPoint Health St. Luke's?
Expedia has 61 hotels and other accommodations a few miles from UnityPoint Health St. Luke's.
If I need to cancel the hotel reservation for my stay near UnityPoint Health St. Luke's, will I receive a refund?
Yes! Most hotel bookings are fully refundable provided that you cancel prior to the accommodation's cancellation deadline, which is often 24 or 48 hours before your check-in date. If you booked a non-refundable reservation, it might still be possible to cancel it and be given a refund within 24 hours of booking. Add dates, click "Search", then you can filter by "fully refundable" to review the best options available near UnityPoint Health St. Luke's.
Where can I learn more about changing or cancelling my trip in the area near UnityPoint Health St. Luke's?
For more details about picking new dates or cancelling your stay near UnityPoint Health St. Luke's, click here.
What can I see and do near UnityPoint Health St. Luke's?
You'll want to browse the collections at The Sioux City Lewis and Clark Interpretive Center, Sergeant Floyd River Museum and Welcome Center, and Dorothy Pecaut Nature Center. You can watch performances at Briar Cliff University Theater, Orpheum Theatre, and Klinger-Neal Theatre if you're interested in local theater. Enjoy the outdoors at Scenic Park, Jeffrey Dibble Sports Complex, or Klasey Park.