$114 Cheap Flights from Des Moines (DSM) to Indianapolis (IND)

View $114 flight on Thu, Sep 4, 2025Opens in a new window

Popular airlines from Des Moines International Airport (DSM) to Indianapolis Intl. Airport (IND)

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Cheap Flights from Des Moines to Indianapolis (DSM-IND)

Prices were available within the past 7 days and start at $114 for one-way flights and $208 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Frontier Airlines
Fri, Oct 31 - Thu, Dec 4
DSM
Des Moines
IND
Indianapolis
$208 Roundtrip, found 4 days ago
$208
Roundtrip
found 4 days ago
Select Frontier Airlines flight, departing Fri, Oct 31 from Des Moines to Indianapolis, returning Thu, Dec 4, priced at $208 found 4 days ago
United
Wed, Sep 3 - Fri, Sep 5
DSM
Des Moines
IND
Indianapolis
$227 Roundtrip, found 20 hours ago
$227
Roundtrip
found 20 hours ago
Select United flight, departing Wed, Sep 3 from Des Moines to Indianapolis, returning Fri, Sep 5, priced at $227 found 20 hours ago
American Airlines
Wed, Sep 3 - Fri, Sep 5
DSM
Des Moines
IND
Indianapolis
$227 Roundtrip, found 20 hours ago
$227
Roundtrip
found 20 hours ago
Select American Airlines flight, departing Wed, Sep 3 from Des Moines to Indianapolis, returning Fri, Sep 5, priced at $227 found 20 hours ago
American Airlines
Wed, Sep 3 - Fri, Sep 5
DSM
Des Moines
IND
Indianapolis
$230 Roundtrip, found 20 hours ago
$230
Roundtrip
found 20 hours ago
Select American Airlines flight, departing Wed, Sep 3 from Des Moines to Indianapolis, returning Fri, Sep 5, priced at $230 found 20 hours ago
United
Thu, Nov 27 - Tue, Dec 2
DSM
Des Moines
IND
Indianapolis
$232 Roundtrip, found 13 hours ago
$232
Roundtrip
found 13 hours ago
Select United flight, departing Thu, Nov 27 from Des Moines to Indianapolis, returning Tue, Dec 2, priced at $232 found 13 hours ago
United
Thu, Nov 27 - Tue, Dec 2
DSM
Des Moines
IND
Indianapolis
$234 Roundtrip, found 13 hours ago
$234
Roundtrip
found 13 hours ago
Select United flight, departing Thu, Nov 27 from Des Moines to Indianapolis, returning Tue, Dec 2, priced at $234 found 13 hours ago
Delta
Wed, Sep 3 - Fri, Sep 5
DSM
Des Moines
IND
Indianapolis
$235 Roundtrip, found 20 hours ago
$235
Roundtrip
found 20 hours ago
Select Delta flight, departing Wed, Sep 3 from Des Moines to Indianapolis, returning Fri, Sep 5, priced at $235 found 20 hours ago
Delta
Wed, Sep 17 - Tue, Sep 30
DSM
Des Moines
IND
Indianapolis
$237 Roundtrip, found 7 hours ago
$237
Roundtrip
found 7 hours ago
Select Delta flight, departing Wed, Sep 17 from Des Moines to Indianapolis, returning Tue, Sep 30, priced at $237 found 7 hours ago
American Airlines
Mon, Oct 27 - Fri, Oct 31
DSM
Des Moines
IND
Indianapolis
$238 Roundtrip, found 5 days ago
$238
Roundtrip
found 5 days ago
Select American Airlines flight, departing Mon, Oct 27 from Des Moines to Indianapolis, returning Fri, Oct 31, priced at $238 found 5 days ago
Southwest Airlines
Wed, Nov 5 - Wed, Dec 3
DSM
Des Moines
IND
Indianapolis
$242 Roundtrip, found 3 days ago
$242
Roundtrip
found 3 days ago
Select Southwest Airlines flight, departing Wed, Nov 5 from Des Moines to Indianapolis, returning Wed, Dec 3, priced at $242 found 3 days ago

Find the cheapest month to fly from Des Moines (DSM) to Indianapolis (IND)

November is typically the cheapest month to fly

From $128 - $434 per traveler.

Graph displaying average flight prices per month

Alternative airports near Indianapolis

Prices were available within the past 7 days. Prices and availability are subject to change.

Select flight to Indianapolis Intl. IND. Cheapest and Closest option available. Average driving time to city center is 19 minutes. Flights from $302
IND
Indianapolis Intl.
CheapestClosest
Average driving time to city center19 min
Flights from $302
Flights from Des Moines (DSM) to Indianapolis (IND)
Origin airport
Des Moines Intl.
Destination airport
Indianapolis Intl.
Airlines serving
American Airlines, Delta, Frontier Airlines, Southwest Airlines, United
Roundtrip price
$208
Distance
405 mi

Des Moines to Indianapolis Flights

The cheapest times to fly from Des Moines to Indianapolis

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Des Moines to Indianapolis are during the month of October. You can find some of the cheapest flights from Des Moines to Indianapolis with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Des Moines to Indianapolis

Sunday is one of the best days to book for cheap flights from Des Moines to Indianapolis: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Des Moines to Indianapolis

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Des Moines to Indianapolis in 2025. You can also book with separate airlines for your outbound and return journeys, from $114 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Des Moines to Indianapolis flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Des Moines to Indianapolis airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Frequently asked questions

How much does a flight from Des Moines Intl. Airport (DSM) to Indianapolis Intl. Airport (IND) cost?
Lock in a cheap one-way flight from $114 or cheap return flight from $208 from Des Moines Intl. Airport (DSM) to Indianapolis Intl. Airport (IND) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to see our cheapest flight offers on this route.
What is the cheapest month to fly from Des Moines Intl. Airport (DSM) to Indianapolis Intl. Airport (IND)?
Traveling in October can help you save, as it's the cheapest month for flights between DSM and IND. You'll usually find the lowest prices during the off-season.
What is the cheapest airline that flies from Des Moines Intl. Airport (DSM) to Indianapolis Intl. Airport (IND)?
Expedia's filter tool lets you easily compare different airlines, flight durations and fares all in one place. Choose your preferences, then sort by "Price (lowest to highest)" to see which carrier offers the cheapest DSM to IND flight.
How many flights per day from Des Moines Intl. Airport (DSM) to Indianapolis Intl. Airport (IND)?
Direct flights from Des Moines Intl. Airport (DSM) to Indianapolis Intl. Airport (IND) aren't available daily, so you'll have to take a flight with a layover. Explore your options with Expedia's filters. Enter your travel dates and pick either "1 Stop" or "2+ Stops."
What day of the week has the most flights from DSM to IND?
Friday is generally the busiest day for flights, while Tuesday is often the quietest.* Just remember that flight schedules can change depending on various factors, including the time of year and carrier.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Des Moines Intl. Airport (DSM) to Indianapolis Intl. Airport (IND)?
Select a flight from Des Moines Intl. Airport (DSM) to Indianapolis Intl. Airport (IND) that leaves before 3 PM to reduce the likelihood of delays and cancellations. Later departures have a 22% higher chance of being canceled, on average.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from Des Moines Intl. Airport (DSM) to Indianapolis Intl. Airport (IND) last-minute?
Booking your plane ticket from DSM to IND just before your getaway is typically more expensive. However, if there's some wiggle room with your departure times and dates, you could bag a cheap last-minute fare.
Is it cheaper to book a DSM to IND flight and hotel package?
Opting for a DSM to IND flight and hotel package tends to be cheaper than booking separately. With Expedia, you can enjoy the ease of organizing your travels all in one place. Pick from our extensive range of stays and then add activities, car rentals and flights to your booking. Bundle it all together, and you could save hundreds of dollars.
Can I cancel or change the date of my flight from Des Moines Intl. Airport (DSM) to Indianapolis Intl. Airport (IND)?
If you reserved your DSM to IND flight in the last 24 hours, you may be able to cancel or modify it without fees. Depending on the airline and the fare type you purchased, additional charges may apply for changes beyond this timeframe. Airline policies and contact information can be found in your itinerary or confirmation email. Or, go to our Customer Service portal if you want more information.

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*Available to One Key members.