$254 Cheap Flights from Gainesville (GNV) to Louisville (SDF)

View $254 flight on Sun, Jan 4, 2026Opens in a new window

Popular airlines from Gainesville Regional Airport (GNV) to Louisville Intl. Airport (SDF)

Cheap Flights from Gainesville to Louisville (GNV-SDF)

Prices were available within the past 7 days and start at $254 for one-way flights and $337 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

American Airlines
Wed, Apr 29 - Sat, May 2
GNV
Gainesville
SDF
Louisville
$337 Roundtrip, found 8 hours ago
$337
Roundtrip
found 8 hours ago
Select American Airlines flight, departing Wed, Apr 29 from Gainesville to Louisville, returning Sat, May 2, priced at $337 found 8 hours ago
Delta
Tue, Jan 13 - Sun, Jan 18
GNV
Gainesville
SDF
Louisville
$347 Roundtrip, found 8 hours ago
$347
Roundtrip
found 8 hours ago
Select Delta flight, departing Tue, Jan 13 from Gainesville to Louisville, returning Sun, Jan 18, priced at $347 found 8 hours ago
Delta
Mon, Nov 24 - Thu, Nov 27
GNV
Gainesville
SDF
Louisville
$357 Roundtrip, found 8 hours ago
$357
Roundtrip
found 8 hours ago
Select Delta flight, departing Mon, Nov 24 from Gainesville to Louisville, returning Thu, Nov 27, priced at $357 found 8 hours ago
American Airlines
Tue, Nov 18 - Tue, Nov 25
GNV
Gainesville
SDF
Louisville
$362 Roundtrip, found 8 hours ago
$362
Roundtrip
found 8 hours ago
Select American Airlines flight, departing Tue, Nov 18 from Gainesville to Louisville, returning Tue, Nov 25, priced at $362 found 8 hours ago
Delta
Tue, Nov 18 - Mon, Nov 24
GNV
Gainesville
SDF
Louisville
$372 Roundtrip, found 13 hours ago
$372
Roundtrip
found 13 hours ago
Select Delta flight, departing Tue, Nov 18 from Gainesville to Louisville, returning Mon, Nov 24, priced at $372 found 13 hours ago
Delta
Tue, Dec 23 - Tue, Jan 6
GNV
Gainesville
SDF
Louisville
$376 Roundtrip, found 3 days ago
$376
Roundtrip
found 3 days ago
Select Delta flight, departing Tue, Dec 23 from Gainesville to Louisville, returning Tue, Jan 6, priced at $376 found 3 days ago
Delta
Tue, Nov 25 - Thu, Nov 27
GNV
Gainesville
SDF
Louisville
$382 Roundtrip, found 2 days ago
$382
Roundtrip
found 2 days ago
Select Delta flight, departing Tue, Nov 25 from Gainesville to Louisville, returning Thu, Nov 27, priced at $382 found 2 days ago
Delta
Sat, Dec 20 - Thu, Jan 1
GNV
Gainesville
SDF
Louisville
$386 Roundtrip, found 3 days ago
$386
Roundtrip
found 3 days ago
Select Delta flight, departing Sat, Dec 20 from Gainesville to Louisville, returning Thu, Jan 1, priced at $386 found 3 days ago
Delta
Tue, Nov 18 - Sun, Nov 23
GNV
Gainesville
SDF
Louisville
$387 Roundtrip, found 13 hours ago
$387
Roundtrip
found 13 hours ago
Select Delta flight, departing Tue, Nov 18 from Gainesville to Louisville, returning Sun, Nov 23, priced at $387 found 13 hours ago
American Airlines
Fri, Nov 21 - Sat, Nov 22
GNV
Gainesville
SDF
Louisville
$392 Roundtrip, found 13 hours ago
$392
Roundtrip
found 13 hours ago
Select American Airlines flight, departing Fri, Nov 21 from Gainesville to Louisville, returning Sat, Nov 22, priced at $392 found 13 hours ago

Alternative airports near Louisville

Prices were available within the past 7 days. Prices and availability are subject to change.

Select flight to Louisville Intl. SDF. Cheapest and Closest option available. Average driving time to city center is 9 minutes. Flights from $407
SDF
Louisville Intl.
CheapestClosest
Average driving time to city center9 min
Flights from $407

Frequently asked questions

How much does a flight from Gainesville Regional Airport (GNV) to Louisville Intl. Airport (SDF) cost?
Secure a cheap one-way flight from $254 or cheap return flight from $337 from Gainesville Regional Airport (GNV) to Louisville Intl. Airport (SDF) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to find our cheapest flight offers on this route.
What is the cheapest month to fly from Gainesville Regional Airport (GNV) to Louisville Intl. Airport (SDF)?
Traveling in April may help you find better deals, as it's the cheapest month for flights between GNV and SDF. You'll often find the lowest prices during the off-season.
What is the cheapest airline that flies from Gainesville Regional Airport (GNV) to Louisville Intl. Airport (SDF)?
Use the filters on Expedia to compare airlines and find the most affordable carrier that'll fly you from GNV to SDF. Then, sort your results by "Price (lowest to highest)" to snag a great deal.
How many flights per day from Gainesville Regional Airport (GNV) to Louisville Intl. Airport (SDF)?
Nonstop flights from Gainesville Regional Airport (GNV) to Louisville Intl. Airport (SDF) aren't available daily, so you'll have to take a flight with a layover. Explore your options with our filter tool. Enter your dates and click on either "1 Stop" or "2+ Stops."
What day of the week has the most flights from GNV to SDF?
Usually you'll find the greatest selection of flight options on a Friday. Tuesdays are often the quietest.* However, this can vary depending on the season, airline and other factors.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Gainesville Regional Airport (GNV) to Louisville Intl. Airport (SDF)?
To avoid possible delays on the Gainesville Regional Airport (GNV) to Louisville Intl. Airport (SDF) route, fly before 3 PM. Departures after this time have a 22% higher chance of being canceled.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from Gainesville Regional Airport (GNV) to Louisville Intl. Airport (SDF) last-minute?
Last-minute bookings from GNV to SDF are typically more expensive. To lock in the best rates, start looking for flights as soon as possible. That being said, if you're flexible with your travel dates, you may land a cheap fare right before your trip.
Is it cheaper to book a GNV to SDF flight and hotel package?
Compared with arranging hotels and flights separately, booking a GNV to SDF flight and hotel package with Expedia could lead to significant savings. Better still, having everything in one convenient place will take the hassle out of planning your trip. Just pick your flights and choose from our wide range of hotels, then tailor your trip with other add-ons like activities and car rentals.
Can I cancel or change the date of my flight from Gainesville Regional Airport (GNV) to Louisville Intl. Airport (SDF)?
If you reserved your GNV to SDF flight in the last 24 hours, you may be able to cancel or modify it at no cost. Depending on the airline and the type of fare you purchased, additional charges may apply for changes beyond this timeframe. Airline policies and contact information can be found in your itinerary or confirmation email. Or, head to our Customer Service portal for more information.

Travel information

Origin airport
Gainesville Regional
Destination airport
Louisville Intl.
Airlines serving
American Airlines, Delta
Roundtrip price
$336
Distance
619 mi

Book with confidence

Gainesville to Louisville Flights

The cheapest times to fly from Gainesville to Louisville

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Gainesville to Louisville are during the month of April. You can find some of the cheapest flights from Gainesville to Louisville with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Gainesville to Louisville

Sunday is one of the best days to book for cheap flights from Gainesville to Louisville: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Gainesville to Louisville

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Gainesville to Louisville in 2025. You can also book with separate airlines for your outbound and return journeys, from $254 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Gainesville to Louisville flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Gainesville to Louisville airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Gainesville to Louisville Flights

Explore a world of travel with Expedia

*Available to One Key members.