$260 Cheap Flights from Guayaquil (GYE) to Santo Domingo (SDQ)

View $260 flight on Thu, Nov 20, 2025Opens in a new window

Popular airlines from Jose Joaquin de Olmedo Intl. Airport (GYE) to Las Americas Intl. Airport (SDQ)

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Cheap Flights from Guayaquil to Santo Domingo (GYE-SDQ)

Prices were available within the past 7 days and start at $260 for one-way flights and $418 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Copa
Fri, Dec 5 - Tue, Dec 9
GYE
Guayaquil
SDQ
Santo Domingo
$418 Roundtrip, found 13 hours ago
$418
Roundtrip
found 13 hours ago
Select Copa flight, departing Fri, Dec 5 from Guayaquil to Santo Domingo, returning Tue, Dec 9, priced at $418 found 13 hours ago
Copa
Fri, Dec 5 - Tue, Dec 9
GYE
Guayaquil
SDQ
Santo Domingo
$430 Roundtrip, found 13 hours ago
$430
Roundtrip
found 13 hours ago
Select Copa flight, departing Fri, Dec 5 from Guayaquil to Santo Domingo, returning Tue, Dec 9, priced at $430 found 13 hours ago
Copa
Fri, Dec 5 - Tue, Dec 9
GYE
Guayaquil
SDQ
Santo Domingo
$439 Roundtrip, found 13 hours ago
$439
Roundtrip
found 13 hours ago
Select Copa flight, departing Fri, Dec 5 from Guayaquil to Santo Domingo, returning Tue, Dec 9, priced at $439 found 13 hours ago
Copa
Fri, Jan 9 - Sun, Jan 11
GYE
Guayaquil
SDQ
Santo Domingo
$442 Roundtrip, found 1 day ago
$442
Roundtrip
found 1 day ago
Select Copa flight, departing Fri, Jan 9 from Guayaquil to Santo Domingo, returning Sun, Jan 11, priced at $442 found 1 day ago
Copa
Fri, Dec 5 - Tue, Dec 9
GYE
Guayaquil
SDQ
Santo Domingo
$451 Roundtrip, found 13 hours ago
$451
Roundtrip
found 13 hours ago
Select Copa flight, departing Fri, Dec 5 from Guayaquil to Santo Domingo, returning Tue, Dec 9, priced at $451 found 13 hours ago
Copa
Mon, Jan 5 - Sat, Jan 17
GYE
Guayaquil
SDQ
Santo Domingo
$452 Roundtrip, found 13 hours ago
$452
Roundtrip
found 13 hours ago
Select Copa flight, departing Mon, Jan 5 from Guayaquil to Santo Domingo, returning Sat, Jan 17, priced at $452 found 13 hours ago
Copa
Mon, Feb 9 - Mon, Mar 2
GYE
Guayaquil
SDQ
Santo Domingo
$454 Roundtrip, found 3 days ago
$454
Roundtrip
found 3 days ago
Select Copa flight, departing Mon, Feb 9 from Guayaquil to Santo Domingo, returning Mon, Mar 2, priced at $454 found 3 days ago
avianca
Tue, Feb 24 - Tue, Mar 10
GYE
Guayaquil
SDQ
Santo Domingo
$477 Roundtrip, found 8 hours ago
$477
Roundtrip
found 8 hours ago
Select avianca flight, departing Tue, Feb 24 from Guayaquil to Santo Domingo, returning Tue, Mar 10, priced at $477 found 8 hours ago
JetBlue Airways
Tue, Nov 18 - Sun, Nov 23
GYE
Guayaquil
SDQ
Santo Domingo
$771 Roundtrip, found 2 days ago
$771
Roundtrip
found 2 days ago
Select JetBlue Airways flight, departing Tue, Nov 18 from Guayaquil to Santo Domingo, returning Sun, Nov 23, priced at $771 found 2 days ago
American Airlines
Tue, Feb 24 - Tue, Mar 10
GYE
Guayaquil
SDQ
Santo Domingo
$1,154 Roundtrip, found 8 hours ago
$1,154
Roundtrip
found 8 hours ago
Select American Airlines flight, departing Tue, Feb 24 from Guayaquil to Santo Domingo, returning Tue, Mar 10, priced at $1,154 found 8 hours ago

Find the cheapest month to fly from Guayaquil (GYE) to Santo Domingo (SDQ)

March is typically the cheapest month to fly

From $323 - $577 per traveler.

Alternative airports near Santo Domingo

Prices were available within the past 7 days. Prices and availability are subject to change.

Select flight to Las Americas Intl. SDQ. Cheapest option available. Average driving time to city center is 22 minutes. Flights from $509
SDQ
Las Americas Intl.
Cheapest
Average driving time to city center22 min
Flights from $509

Frequently asked questions

How much does a flight from Jose Joaquin de Olmedo Intl. Airport (GYE) to Las Americas Intl. Airport (SDQ) cost?
Get a cheap one-way flight from $260 or cheap return flight from $418 from Jose Joaquin de Olmedo Intl. Airport (GYE) to Las Americas Intl. Airport (SDQ) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to see our cheapest flight deals on this route.
What is the cheapest month to fly from Jose Joaquin de Olmedo Intl. Airport (GYE) to Las Americas Intl. Airport (SDQ)?
December is the least expensive month to fly from GYE to SDQ. Traveling during quieter months is often the key to better flight prices.
What is the cheapest airline that flies from Jose Joaquin de Olmedo Intl. Airport (GYE) to Las Americas Intl. Airport (SDQ)?
To find the cheapest airline flying from GYE to SDQ, use Expedia's filter tool. Customize your search based on your travel needs, such as preferred carriers and flight duration. You can then sort your results by "Price (lowest to highest)" to discover the cheapest flight right away.
How many flights per day from Jose Joaquin de Olmedo Intl. Airport (GYE) to Las Americas Intl. Airport (SDQ)?
Nonstop flights from Jose Joaquin de Olmedo Intl. Airport (GYE) to Las Americas Intl. Airport (SDQ) aren't available daily, so you'll need to take a flight with a layover. Explore your options with our filter tool. Enter your travel details and pick either "1 Stop" or "2+ Stops."
What day of the week has the most flights from GYE to SDQ?
Friday is typically the busiest day for flights, while Tuesday tends to be the quietest.* Remember that flight schedules can change based on a number of factors, such as the time of year and carrier.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What airline has the least delays from GYE to SDQ?
Consider traveling with Arajet if you'd like to fly straight from Jose Joaquin de Olmedo Intl. Airport (GYE) to Las Americas Intl. Airport (SDQ) without any delays. This carrier has the strongest track record for punctuality, with an on-time score of 100%. Want to get notified of any changes? You can keep an eye on your flight status using the Expedia App.
What is the best time to fly from Jose Joaquin de Olmedo Intl. Airport (GYE) to Las Americas Intl. Airport (SDQ)?
To land at Las Americas Intl. Airport (SDQ) on schedule, book a flight that leaves Jose Joaquin de Olmedo Intl. Airport (GYE) before 3 PM. The chance of cancellations is 22% higher, on average, for departures after this hour.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from Jose Joaquin de Olmedo Intl. Airport (GYE) to Las Americas Intl. Airport (SDQ) last-minute?
Last-minute fares from GYE to SDQ are generally more expensive. To lock in the lowest rates, start searching for flights early. That said, if you're flexible with your travel plans, you may score a cheap ticket just before your departure.
Is it cheaper to book a GYE to SDQ flight and hotel package?
Booking a GYE to SDQ flight and hotel package is generally cheaper than booking separately. With Expedia, you can enjoy the convenience of organizing your trip all in one place. Pick from our wide range of hotels and then add activities, flights and car rentals to your booking. Bundle everything together, and you could save hundreds of dollars.
Can I cancel or change the date of my flight from Jose Joaquin de Olmedo Intl. Airport (GYE) to Las Americas Intl. Airport (SDQ)?
In most instances, you're able to cancel or reschedule your GYE to SDQ flight. However, additional charges may apply, especially if you booked more than 24 hours ago. Double-check your itinerary for the airline's policies and fees on flight changes, or if you need more details, visit our Customer Service portal.

Travel information

Origin airport
Jose Joaquin de Olmedo Intl.
Destination airport
Las Americas Intl.
Airlines serving
American Airlines, Copa, avianca
Roundtrip price
$417
Distance
1582 mi

Book with confidence

Guayaquil to Santo Domingo Flights

The cheapest times to fly from Guayaquil to Santo Domingo

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Guayaquil to Santo Domingo are during the month of December. You can find some of the cheapest flights from Guayaquil to Santo Domingo with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Guayaquil to Santo Domingo

Sunday is one of the best days to book for cheap flights from Guayaquil to Santo Domingo: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Guayaquil to Santo Domingo

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Guayaquil to Santo Domingo in 2025. You can also book with separate airlines for your outbound and return journeys, from $260 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Guayaquil to Santo Domingo flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Guayaquil to Santo Domingo airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Guayaquil to Santo Domingo Flights

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