$624 Cheap Flights from Chicago (MDW) to Reynosa (REX)

View $624 flight on Sat, Nov 15, 2025Opens in a new window

Popular airlines from Chicago Midway Airport (MDW) to Reynosa, Tamaulipas (REX-General Lucio Blanco Intl.)

Cheap Flights from Chicago to Reynosa (MDW-REX)

Prices were available within the past 7 days and start at $624 for one-way flights and $1,165 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Aeromexico
Sat, Nov 15 - Sat, Nov 22
MDW
Chicago
REX
Reynosa
$1,165 Roundtrip, found 2 days ago
$1,165
Roundtrip
found 2 days ago
Select Aeromexico flight, departing Sat, Nov 15 from Chicago to Reynosa, returning Sat, Nov 22, priced at $1,165 found 2 days ago
Aeromexico
Sat, Nov 8 - Tue, Nov 11
MDW
Chicago
REX
Reynosa
$1,168 Roundtrip, found 5 hours ago
$1,168
Roundtrip
found 5 hours ago
Select Aeromexico flight, departing Sat, Nov 8 from Chicago to Reynosa, returning Tue, Nov 11, priced at $1,168 found 5 hours ago
Aeromexico
Sat, Nov 15 - Sat, Nov 22
MDW
Chicago
REX
Reynosa
$1,235 Roundtrip, found 2 days ago
$1,235
Roundtrip
found 2 days ago
Select Aeromexico flight, departing Sat, Nov 15 from Chicago to Reynosa, returning Sat, Nov 22, priced at $1,235 found 2 days ago
Aeromexico
Sat, Nov 8 - Tue, Nov 11
MDW
Chicago
REX
Reynosa
$1,241 Roundtrip, found 5 hours ago
$1,241
Roundtrip
found 5 hours ago
Select Aeromexico flight, departing Sat, Nov 8 from Chicago to Reynosa, returning Tue, Nov 11, priced at $1,241 found 5 hours ago
Aeromexico
Sat, Nov 15 - Sat, Nov 22
MDW
Chicago
REX
Reynosa
$1,337 Roundtrip, found 2 days ago
$1,337
Roundtrip
found 2 days ago
Select Aeromexico flight, departing Sat, Nov 15 from Chicago to Reynosa, returning Sat, Nov 22, priced at $1,337 found 2 days ago
Aeromexico
Sat, Nov 15 - Sat, Nov 22
MDW
Chicago
REX
Reynosa
$1,392 Roundtrip, found 2 days ago
$1,392
Roundtrip
found 2 days ago
Select Aeromexico flight, departing Sat, Nov 15 from Chicago to Reynosa, returning Sat, Nov 22, priced at $1,392 found 2 days ago
Aeromexico
Sat, Nov 15 - Sat, Nov 22
MDW
Chicago
REX
Reynosa
$1,442 Roundtrip, found 2 days ago
$1,442
Roundtrip
found 2 days ago
Select Aeromexico flight, departing Sat, Nov 15 from Chicago to Reynosa, returning Sat, Nov 22, priced at $1,442 found 2 days ago
Aeromexico
Sat, Nov 8 - Tue, Nov 11
MDW
Chicago
REX
Reynosa
$1,480 Roundtrip, found 5 hours ago
$1,480
Roundtrip
found 5 hours ago
Select Aeromexico flight, departing Sat, Nov 8 from Chicago to Reynosa, returning Tue, Nov 11, priced at $1,480 found 5 hours ago
Aeromexico
Sat, Nov 15 - Sat, Nov 22
MDW
Chicago
REX
Reynosa
$1,520 Roundtrip, found 2 days ago
$1,520
Roundtrip
found 2 days ago
Select Aeromexico flight, departing Sat, Nov 15 from Chicago to Reynosa, returning Sat, Nov 22, priced at $1,520 found 2 days ago
Aeromexico
Sat, Nov 8 - Tue, Nov 11
MDW
Chicago
REX
Reynosa
$1,630 Roundtrip, found 5 hours ago
$1,630
Roundtrip
found 5 hours ago
Select Aeromexico flight, departing Sat, Nov 8 from Chicago to Reynosa, returning Tue, Nov 11, priced at $1,630 found 5 hours ago

Alternative airports near Reynosa

Prices were available within the past 7 days. Prices and availability are subject to change.

Select flight to Miller Intl. MFE. Cheapest option available. Average driving time to city center is 1 hour 3 minutes. Flights from $773
MFE
Miller Intl.
Cheapest
Average driving time to city center1 h 3 min
Flights from $773

Frequently asked questions

How much does a flight from Midway Intl. Airport (MDW) to General Lucio Blanco Intl. Airport (REX) cost?
Get a cheap one-way flight from $624 or cheap return flight from $1,165 from Midway Intl. Airport (MDW) to General Lucio Blanco Intl. Airport (REX) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to find our cheapest flight offers on this route.
What is the cheapest month to fly from Midway Intl. Airport (MDW) to General Lucio Blanco Intl. Airport (REX)?
Planning your trip for November can help you save, as it's the cheapest month for flights between MDW and REX. You'll usually find the lowest prices during the off-season.
What is the cheapest airline that flies from Midway Intl. Airport (MDW) to General Lucio Blanco Intl. Airport (REX)?
To find the cheapest airline that'll fly you from MDW to REX, use Expedia's filter tool. Tailor your search based on what matters most to you, such as preferred carriers and cabin class. You can then sort your results by "Price (lowest to highest)" to discover the cheapest flight right away.
How many flights per day from Midway Intl. Airport (MDW) to General Lucio Blanco Intl. Airport (REX)?
There are no daily nonstop flights from Midway Intl. Airport (MDW) to General Lucio Blanco Intl. Airport (REX). But you can book flights with layovers. Filter your search on Expedia to include one or more stops, and you'll be cruising above the clouds in no time.
What day of the week has the most flights from MDW to REX?
Typically you'll find the largest variety of flight choices on a Friday. Tuesdays tend to be the quietest.* However, this can change based on the season, carrier and other factors.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Midway Intl. Airport (MDW) to General Lucio Blanco Intl. Airport (REX)?
To reach General Lucio Blanco Intl. Airport (REX) on schedule, opt for a flight that leaves Midway Intl. Airport (MDW) before 3 PM. The likelihood of cancellations is 22% higher, on average, for departures after this hour.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from Midway Intl. Airport (MDW) to General Lucio Blanco Intl. Airport (REX) last-minute?
Last-minute fares from MDW to REX are usually more expensive. To lock in the lowest prices, start looking for flights as early as possible. That being said, if you're flexible with your travel dates, you may find a cheap ticket right before your journey.
Is it cheaper to book a MDW to REX flight and hotel package?
You can save money by securing a MDW to REX flight and hotel package compared to booking separately. In fact, travelers could save hundreds of dollars by bundling with Expedia. And it's easy to manage everything in one place. Once you've selected your preferred accommodations and flights, you can add extras such as activities, tours and car rentals.
Can I cancel or change the date of my flight from Midway Intl. Airport (MDW) to General Lucio Blanco Intl. Airport (REX)?
Generally, it's possible to reschedule or cancel your MDW to REX flight. However, if it's been more than 24 hours since booking, additional fees may apply. Check your airline's policies in your itinerary to see what changes are possible and whether any costs are involved. You'll also find more details on our Customer Service portal.

Travel information

Travel information

Origin airport
Midway Intl.
Destination airport
General Lucio Blanco Intl.
Roundtrip price
$1,164
Distance
1242 mi

Book with confidence

Book with confidence

Chicago to Reynosa Flights

The cheapest times to fly from Chicago to Reynosa

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Chicago to Reynosa are during the month of November. You can find some of the cheapest flights from Chicago to Reynosa with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Chicago to Reynosa

Sunday is one of the best days to book for cheap flights from Chicago to Reynosa: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Chicago to Reynosa

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Chicago to Reynosa in 2025. You can also book with separate airlines for your outbound and return journeys, from $624 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Chicago to Reynosa flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Chicago to Reynosa airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Chicago to Reynosa Flights

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*Available to One Key members.