Cheap Flights from Knoxville (TYS) to Muscle Shoals (MSL)

Popular airlines from McGhee Tyson Airport (TYS) to Muscle Shoals, AL (MSL-Northwest Alabama Regional)

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Frequently asked questions

How much does a flight from McGhee Tyson Airport (TYS) to Northwest Alabama Regional Airport (MSL) cost?
Lock in a cheap one-way flight or cheap return flight from McGhee Tyson Airport (TYS) to Northwest Alabama Regional Airport (MSL) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to see our cheapest flight offers on this route.
What is the cheapest month to fly from McGhee Tyson Airport (TYS) to Northwest Alabama Regional Airport (MSL)?
The cheapest month to fly from TYS to MSL is , when there's less demand. Off-peak months are generally when airlines offer lower prices between these airports.
What is the cheapest airline that flies from McGhee Tyson Airport (TYS) to Northwest Alabama Regional Airport (MSL)?
Expedia's filter tool lets you easily compare different airlines, flight durations and fares all in one place. Tailor the search to your trip, then sort by "Price (lowest to highest)" to see which carrier offers the cheapest TYS to MSL flight.
How many flights per day from McGhee Tyson Airport (TYS) to Northwest Alabama Regional Airport (MSL)?
You'll need to hop on a flight with a layover if you're traveling from McGhee Tyson Airport (TYS) to Northwest Alabama Regional Airport (MSL). There are no daily direct flights on this route. However, simply filter your search to include one or more stops to find the best option for your trip.
What day of the week has the most flights from TYS to MSL?
Typically you'll find the largest variety of flight choices on a Friday. Tuesdays are often the quietest.* However, this can vary depending on the season, carrier and other factors.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from McGhee Tyson Airport (TYS) to Northwest Alabama Regional Airport (MSL)?
To reach Northwest Alabama Regional Airport (MSL) without delays, select a flight that takes off from McGhee Tyson Airport (TYS) before 3 PM. The chance of cancellations is 22% higher, on average, for departures after this hour.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from McGhee Tyson Airport (TYS) to Northwest Alabama Regional Airport (MSL) last-minute?
Booking your plane ticket from TYS to MSL shortly before your getaway is typically more expensive. However, if there's some wiggle room with your travel times and dates, you could bag a cheap last-minute fare.
Is it cheaper to book a TYS to MSL flight and hotel package?
You'll generally save money by securing a TYS to MSL flight and hotel package compared to booking separately. In fact, you could save hundreds of dollars by bundling with Expedia. And it's simple to manage it all in one convenient place. After choosing your preferred flights and accommodations, you can add extras like activities, tours and car rentals.
Can I cancel or change the date of my flight from McGhee Tyson Airport (TYS) to Northwest Alabama Regional Airport (MSL)?
If you reserved your TYS to MSL flight in the last 24 hours, you may be able to cancel or modify it without fees. Depending on the airline and the type of fare you purchased, additional charges may apply for changes beyond this timeframe. Airline policies and contact information can be found in your itinerary or confirmation email. Or, visit our Customer Service portal for more information.

Travel information

Origin airport
McGhee Tyson
Destination airport
Northwest Alabama Regional
Distance
217 mi

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Knoxville to Muscle Shoals Flights

The cheapest times to fly from Knoxville to Muscle Shoals

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Knoxville to Muscle Shoals are during the month of . You can find some of the cheapest flights from Knoxville to Muscle Shoals with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Knoxville to Muscle Shoals

Sunday is one of the best days to book for cheap flights from Knoxville to Muscle Shoals: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Knoxville to Muscle Shoals

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Knoxville to Muscle Shoals in 2026. You can also book with separate airlines for your outbound and return journeys, from one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Knoxville to Muscle Shoals flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Knoxville to Muscle Shoals airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Knoxville to Muscle Shoals Flights

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