Find 4 Star Hotels in Pickens, SC from $134

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Compare Pickens 4 Star Hotels with updated room rates, reviews, and availability. Most hotels are fully refundable.

Grand Bohemian Lodge Greenville, Autograph Collection

4.0 star property
Greenville Downtown
9.6 out of 10, Exceptional, (415)
"Absolutely one of the best hotels to stay at. "
United States
stephen
$295 nightly
The price is $324
Jan 4 - Jan 5, 2026
Total with taxes and fees
Grand Bohemian Lodge Greenville, Autograph Collection

The Westin Poinsett Greenville

4.0 star property
Greenville Downtown
9.2 out of 10, Wonderful, (1003)
"Awesome place "
United States
Dominick
$159 nightly
The price is $175
Dec 22 - Dec 23
Total with taxes and fees
The Westin Poinsett Greenville

The Shepherd Hotel Downtown Clemson

4.0 star property
Clemson
9.8 out of 10, Exceptional, (738)
"Wonderful staff, great location"
United States
Shelly
$157 nightly
The price is $175
Dec 14 - Dec 15
Total with taxes and fees
The Shepherd Hotel Downtown Clemson

Mint House Greenville - Downtown

4.0 star property
Greenville Downtown
9.2 out of 10, Wonderful, (772)
"Excellent stay as always! "
United States
Elena
$122 nightly
The price is $134
Dec 21 - Dec 22
Total with taxes and fees
Mint House Greenville - Downtown

The Abernathy of Clemson

4.0 star property
Clemson
9.6 out of 10, Exceptional, (555)
"location is amazing! "
United States
colleen
$145 nightly
The price is $161
Dec 9 - Dec 10
Total with taxes and fees
The Abernathy of Clemson

Park Place Apartments by Landing

4.0 star property
Greenville
7.6 out of 10, Good, (42)
"Loved the apartment! Very spacious, clean, brand new. Access to bike paths. Seemed like a quirky location but everything is close by car or bike. "
United States
Kathie
Park Place Apartments by Landing

The Station by Compo Hotels

4.0 star property
Travelers Rest
10.0 out of 10, Exceptional, (15)
"great place perfect for more privacy vs. a standard hotel"
United States
John
$268 nightly
The price is $295
Jan 5 - Jan 6, 2026
Total with taxes and fees
The Station by Compo Hotels

Hotel Domestique

4.0 star property
Travelers Rest
9.6 out of 10, Exceptional, (30)
"Overall it was an exceptional experience and would highly recommend to anyone looking for a quiet get away."
United States
Chuck
$275 nightly
The price is $303
Jan 8 - Jan 9, 2026
Total with taxes and fees
Hotel Domestique

Tuxedo Falls

4.0 star property
Zirconia
10.0 out of 10, Exceptional, (3)
"This is, by far, one of the greatest stays we have ever had! The cabin was brand new and was impeccable from the bathroom to the living space, to the pizza grill. The mini kitchenette was stocked with everything we would need, including beautiful local pottery and glassware. The porch was so spacious, and our girls (12 & 13) deemed this the best place to stay EVER. The hiking trails along the creeks and waterfalls were so beautiful! The owners were so responsive to any of our requests, including...
United States
rebecca
Tuxedo Falls

Liberty Hall Bed and Breakfast

4.0 star property
Pendleton
10.0 out of 10, Exceptional, (78)
"The owners are amazing. Comfy rooms, stellar breakfast and good people. "
United States
Renee
$189 nightly
The price is $209
Dec 20 - Dec 21
Total with taxes and fees
Liberty Hall Bed and Breakfast

Southern Sunshine Retreat

4.0 star property
Easley
Southern Sunshine Retreat

Lake Hartwell Frank Howard Home Clemson

4.0 star property
Anderson
$266 nightly
The price is $295
Dec 9 - Dec 10
Total with taxes and fees
Lake Hartwell Frank Howard Home Clemson

Belvedere

4.0 star property
Anderson
8.0 out of 10, Very Good, (1)
"Bring everything. Including hangers for your clothes, salt and pepper, etc. it is like staying at a place that has one purpose, to rent out. Beds are uncomfortable. Nice big closets with one wire hanger. Why??? "
United States
CANDACE
Belvedere

Pendleton

4.0 star property
Pendleton
Pendleton

Randall St , 202/204

4.0 star property
Greenville
Randall St , 202/204

Historic Miller's Bungalow

4.0 star property
Central
Historic Miller's Bungalow

140 Catlin Circle

4.0 star property
Greenville
140 Catlin Circle

34 Allen St

4.0 star property
Greenville
34 Allen St
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Learn more about Pickens

Nestled in the foothills of the Blue Ridge Mountains, this charming town offers a slice of small-town Americana. Hike the trails at Table Rock State Park, then explore the Hagood Mill Historic Site to experience local heritage and traditional bluegrass music.

Table Rock State Park South Carolina Blue Ridge Mountains Landscape sunrise morning scenic photography

Top Pickens Hotel Reviews

Find out more about Pickens

Pickens Four Star Hotel Information

When you need to book a room with luxurious amazing amenities and the best rates, the 4 star hotels in Pickens, South Carolina are incredible options. Known for their extra perks, first-rate service, and fantastic locations, each of the Pickens 4 star hotels offers the ultimate experience for globe-trotting travelers. Relax in your expertly designed room. Kick back with around-the-clock room service.

Get a good night’s sleep with the ultra-plush bedding, and freshen up in the morning with designer-inspired body products. It’s all available when you stay at one of the top book a four star hotels in Pickens. What’s more, thanks to Expedia you might even score a cheap great deal on a 4 star hotel in Pickens, South Carolina, areas near the hottest attractions, so you can plan a sightseeing adventure and take advantage of unbeatable discounts in one fell swoop.

Whether you’re putting together a serene getaway or want to revel in the most vibrant entertainment district, 4 star Pickens hotels offer everything your heart desires.

Frequently asked questions

How much does it cost to stay in a 4-star hotel in Pickens?
Expedia can help you easily find the ideal 4-star hotel for your vacation in Pickens. Use our handy filter tool to tailor your search by things like price, amenities and hotel star rating and get access to fabulous deals in a couple of clicks.

  • Search for the lowest price from $134

What's the difference between 5-star and 4-star hotels in Pickens?
If you choose to book a stay at a 4-star hotel in Pickens, you'll typically find plenty of amenities to make sure you're relaxed, such as a restaurant, pool and gym. You can enjoy top-quality service and upmarket accommodations. Go for a 5-star hotel and you'll get a few extra perks — think on-site spas, 24-hour front desk and nightly turndown services. You're likely to get extra amenities and premium services at a 5-star getaway, but both are awesome options for luxury guests.
Does Pickens have any 4-star all-inclusive resorts?
Use our "All inclusive" filter to find your next dream getaway in Pickens where everything is taken care of, from your accommodations to your meals, entertainment and activities. We can also help you find standard 4-star stays in and around this popular destination.

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