Are there any 4-star casino hotels in Salem?

Use our convenient filter tool to narrow down your Salem search by amenities, star rating and more. Whether you're craving the complete casino resort experience or simply want to test out your luck while letting your hair down in 4-star style, you're sure to find a place that strikes just the right balance between entertainment and relaxation.

Lake Jocassee is a 7,500-acre, 300-foot deep reservoir located in northwest South Carolina created by the state in partnership with Duke Power in 1973. The lake is commonly known for the clean and cold Appalachian mountain rivers that feed the lake to keep its waters cool and clear year-round. I love kayaking here surrounded by mountains and several water fall around the lake.

Find 4 Star Hotels in Salem, SC from $149

Upfront pricing
Our total price for your stay includes taxes and fees
Treat yourself
Save 10% or more on over 100,000 hotels worldwide with Member Prices
Learn about One Key
Be picky
Search almost a million properties worldwide

Check availability on Salem 4 Star Hotels

Tonight

Tomorrow

This weekend

Next weekend

Our top choices for Salem 4-star hotels

The Shepherd Hotel Downtown Clemson

Clemson

Amanda R

$155 nightly

Dec 28 - Dec 29

Total with taxes and fees

Trailborn Highlands, Outdoor Collection by Marriott Bonvoy

Highlands

Stephen

$149 nightly

Dec 17 - Dec 18

Total with taxes and fees

The Abernathy of Clemson

Clemson

colleen

$134 nightly

Dec 31 - Jan 1, 2026

Total with taxes and fees

Liberty Hall Bed and Breakfast

Pendleton

Renee

$242 nightly

Jan 13 - Jan 14, 2026

Total with taxes and fees

Signature House, 4 Bedrooms, Patio | In-room dining

Lake Hartwell Frank Howard Home Clemson

Anderson

$283 nightly

Jan 1 - Jan 2, 2026

Total with taxes and fees

Family House, 4 Bedrooms, Patio, Courtyard View | Private kitchen | Fridge, microwave, oven, stovetop

Belvedere

Anderson

CANDACE

Superior Room, 1 King Bed, Balcony (Courtyard Superior King Bal Fireplace) | Deep soaking bathtub

Half-Mile Farm

Highlands Hills

Jodi

Comfort House, 3 Bedrooms, Non Smoking, Fireplace | Living room | 65-inch Smart TV with cable channels, fireplace, Netflix

Pendleton

Save an average of 15% on thousands of hotels when you're signed in

Learn more about Salem

Nestled along Lake Keowee, this small town offers peaceful fishing spots and scenic hiking trails in Devils Fork State Park. Rent a pontoon boat to explore the lake's hidden coves or visit nearby Oconee State Park for waterfall views.

See all hotels in Salem

Top Salem Hotel Reviews

The Shepherd Hotel Downtown Clemson

10/10 Excellent

"This hotel is wonderful and the location is perfect! "

Trailborn Highlands, Outdoor Collection by Marriott Bonvoy

10/10 Excellent

"Friendly staff. Great location. Large rooms. "

Find out more about Salem

Salem Four Star Hotel Information

When you need to book a room with luxurious amazing amenities and the best rates, the 4 star hotels in Salem, South Carolina are incredible options. Known for their extra perks, first-rate service, and fantastic locations, each of the Salem 4 star hotels offers the ultimate experience for globe-trotting travelers. Relax in your expertly designed room. Kick back with around-the-clock room service.

Get a good night’s sleep with the ultra-plush bedding, and freshen up in the morning with designer-inspired body products. It’s all available when you stay at one of the top book a four star hotels in Salem. What’s more, thanks to Expedia you might even score a cheap great deal on a 4 star hotel in Salem, South Carolina, areas near the hottest attractions, so you can plan a sightseeing adventure and take advantage of unbeatable discounts in one fell swoop.

Whether you’re putting together a serene getaway or want to revel in the most vibrant entertainment district, 4 star Salem hotels offer everything your heart desires.

Frequently asked questions

How much does it cost to stay in a 4-star hotel in Salem?

To lock in a 4-star hotel in Salem that matches your budget, take advantage of Expedia's sort and search filters. Take a look at the available options during your chosen dates and use our pricing filter to set your maximum rate. You can also sort your results by the most affordable retreat first.

Search for the lowest price from $149

What's the difference between 5-star and 4-star hotels in Salem?

Offering a welcoming traveler experience and upmarket surroundings, 4-star hotels are a wonderful option for your Salem trip. These kinds of accommodations generally feature lots of useful amenities that make it simple to kick back and relax — think complimentary bathrobes, pools and gyms. Or live the high life at a 5-star hotel designed to spoil you with exclusive perks and amenities. Round-the-clock concierge service, oversized bathrooms and world-class dining are typically included at these plush properties.

Does Salem have any 4-star all-inclusive resorts?

Enjoy a stress-free vacation experience where just about everything is included in the one rate by using our "All inclusive" filter. Sticking to your budget is simple when your room, food, activities and entertainment are already taken care of. After something different? Browse the amazing deals on our standard 4-star stays in and around Salem too.

Find 4 Star Hotels in Salem, SC from $149

Upfront pricing

Treat yourself

Be picky

Check availability on Salem 4 Star Hotels

Our top choices for Salem 4-star hotels

The Shepherd Hotel Downtown Clemson

Trailborn Highlands, Outdoor Collection by Marriott Bonvoy

The Abernathy of Clemson

Liberty Hall Bed and Breakfast

Lake Hartwell Frank Howard Home Clemson

Belvedere

Half-Mile Farm

Pendleton

Historic Miller's Bungalow

Learn more about Salem

Top Salem Hotel Reviews

The Shepherd Hotel Downtown Clemson

Trailborn Highlands, Outdoor Collection by Marriott Bonvoy

Find out more about Salem

Salem Four Star Hotel Information

Frequently asked questions

Explore a world of travel with Expedia