Find 5 Star Hotels in Hyannis, MA from $130

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Our top choices for Hyannis 5-star hotels

Seasonal outdoor pool
Chatham Bars Inn

Chatham Bars Inn

5.0 star property
Chatham
9.2 out of 10, Wonderful, (797)
"Great accommodation and staff."
United States
Michael
$273 nightly
The price is $312
Dec 14 - Dec 15
Total with taxes and fees
Chatham Bars Inn
Beach bar
Wequassett Resort and Golf Club

Wequassett Resort and Golf Club

5.0 star property
Harwich
9.4 out of 10, Exceptional, (241)
"Our Room looked over the beautiful gardens and out to the cove where small boats were bouyed. Very nicely appointed Room and superb weather during our stay. "
United States
Charles
$368 nightly
The price is $421
Dec 25 - Dec 26
Total with taxes and fees
Wequassett Resort and Golf Club
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Explore similar 4-star hotels

Many 4-star hotels have the same amenities as 5-star hotels. See all 4-star hotels in Hyannis.
Margaritaville Resort Cape Cod

Margaritaville Resort Cape Cod

1225 Iyannough Rd Hyannis MA
$194 nightly
The price is $222 total per night from Jan 5 to Jan 6
$222 total
Jan 5 - Jan 6, 2026
Total with taxes and fees
8.6/10 Excellent! (409 reviews)
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Learn more about Hyannis

Stroll the bustling harbor and hop aboard a ferry to Martha's Vineyard or Nantucket for a day trip. Visit the John F. Kennedy Hyannis Museum to learn about the president's connection to Cape Cod's summer playground.

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Hyannis showing a marina and a bay or harbor

Top Hyannis Hotel Reviews

Find out more about Hyannis

There's nothing wrong with enjoying the finer things in life. Treat your every whim on your impending break. There's no reason to delay a getaway to Hyannis any longer. You'll join the multitudes of vacationers who have made Hyannis so fashionable in the last year. The hotels in Hyannis also offer great customer service, averaging 3.7 in our ranking system, giving you a lot to look forward to. Don't wait any longer. Reserve one of our 5-star hotels in Hyannis and indulge in the finer things in life for a while.

Get a Great Deal on 5-Star Hotels in Hyannis

You can expect superior customer service from your hotel. Excellent customer care, luxurious bedding, and fabulous spa offerings are waiting for you. You're sure to find exactly the accommodation you need. You'll be pleased to note that the hotels in Hyannis offer great customer service, averaging 3.7 in our ranking system, setting you up for a truly relaxing getaway. How do you want to relax? 24-hour room service, so you can order that filet mignon in the wee hours of the morning? A body scrub that will leave you feeling outstanding? Butler services? No matter what you want on a perfect getaway, you're bound to find it here. Don't want to take our word for it? Then explore the 551 reviews various guests have left on Expedia and get to know these places.

Yearning for experiences outside your hotel room? We've got you covered. From doing a bit of shopping to embracing the great outdoors, you'll never be bored on this retreat. No matter what you end up doing, the 5-star hotels in Hyannis are waiting for you to relax after an exciting day.

Make Your Escape

The results are in, and Hyannis 5-star hotels are the place to be when you book your next vacation. Many visitors recommend a trip to this location, so don't wait any longer. Don't put off your dream vacation any longer -- Expedia can help you land a great deal on accommodation. Opt for one of our Hyannis 5-star hotels today and decompress in complete comfort when you're ready.

Frequently asked questions

How much does it cost to stay in a 5-star hotel in Hyannis?
The amount you pay for a 5-star hotel in Hyannis can vary depending on when you prefer to travel and how long you plan to stay, among other factors. Use our price per night filter and other search tools to find the best rate on a plush stay.

  • Search for the lowest price per night from $130

What makes a hotel 5 stars in Hyannis?
Exemplary guest service is the hallmark of every 5-star hotel in Hyannis. From the minute you arrive, staff cater to your every whim, whether recommending activities or providing in-room beauty treatments. What's more, hotels must offer top-rate conveniences to be eligible for a 5-star rating. These can include luxury baths, spas or saunas, swimming pools, fine dining restaurants and knowledgeable concierge.
Are there any 5-star all-inclusive resorts in Hyannis?
Expedia's filter tool is the quickest way to find exactly what you want. Select "5-star" and "All inclusive" to see the most luxurious resorts in Hyannis where your accommodations, meals, activities and entertainment are included in the upfront price. At these getaways, your trip is absolute indulgence from the moment you pull up to the entrance.

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