Find Adults Only Resorts & Hotels in Downtown Panama City, FL from $69

Start date: Check-in selected.
To Date
End date: Check-out
  • Upfront pricing

    Our total price for your stay includes taxes and fees
  • Treat yourself

    Save 10% or more on over 100,000 hotels worldwide with Member Prices
  • Be picky

    Search almost a million properties worldwide

Check availability on Downtown Panama City Adults Only Resorts & Hotels

No exact matches found, but these alternatives could be just right

Recommended hotels in Downtown Panama City

Hotel Indigo Panama City Marina by IHG

Hotel Indigo Panama City Marina by IHG
3.5 star property
Downtown Panama City
9.6 out of 10, Exceptional, (336)
"Great place "
United States
Kaniesha
$128 nightly
The price is $144
Dec 14 - Dec 15
Total with taxes and fees
Hotel Indigo Panama City Marina by IHG

Seas The Day Regency Towers 1122-Beachfront-Renovated! Fantastic Views!

Seas The Day Regency Towers 1122-Beachfront-Renovated! Fantastic Views!
Downtown Panama City
9.0 out of 10, Wonderful, (21)
"This property exceeded our expectations and we will be booking again!"
United States
SaMone' S.
$360 nightly
The price is $400
Dec 11 - Dec 12
Total with taxes and fees
Seas The Day Regency Towers 1122-Beachfront-Renovated! Fantastic Views!

Hyatt Place Panama City Beach

Hyatt Place Panama City Beach
3.0 star property
Panama City Beach
9.4 out of 10, Exceptional, (1468)
"Great hotel! "
United States
Demetrius
$84 nightly
The price is $95
Dec 14 - Dec 15
Total with taxes and fees
Hyatt Place Panama City Beach

Holiday Inn Resort Panama City Beach by IHG

Holiday Inn Resort Panama City Beach by IHG
3.5 star property
Panama City Beach
9.2 out of 10, Wonderful, (1240)
"The resort was beautiful "
United States
Esther Castellano
$137 nightly
The price is $155
Dec 14 - Dec 15
Total with taxes and fees
Holiday Inn Resort Panama City Beach by IHG

Hampton Inn & Suites Panama City Beach-Beachfront

Hampton Inn & Suites Panama City Beach-Beachfront
2.5 star property
Panama City Beach
8.8 out of 10, Excellent, (2216)
"Great staff, amazing view"
United States
Amy
$75 nightly
The price is $85
Dec 18 - Dec 19
Total with taxes and fees
Hampton Inn & Suites Panama City Beach-Beachfront

Tru By Hilton Panama City Beach

Tru By Hilton Panama City Beach
2.5 star property
Panama City Beach
8.6 out of 10, Excellent, (410)
"Very nice rooms, easy check in, good breakfast options, staff was very friendly! Would definitely stay here again. "
United States
Lisa
$62 nightly
The price is $69
Dec 21 - Dec 22
Total with taxes and fees
Tru By Hilton Panama City Beach

Homewood Suites by Hilton Panama City Beach

Homewood Suites by Hilton Panama City Beach
3.0 star property
Panama City Beach
9.4 out of 10, Exceptional, (622)
"Friendly staff, clean room, good breakfast."
United States
Brian
$99 nightly
The price is $111
Jan 2 - Jan 3, 2026
Total with taxes and fees
Homewood Suites by Hilton Panama City Beach

SpringHill Suites by Marriott Panama City Beach Beachfront

SpringHill Suites by Marriott Panama City Beach Beachfront
2.5 star property
Panama City Beach
9.0 out of 10, Wonderful, (1069)
"Staff was very friendly. Would stay here again"
United States
YVONNE Maria
$89 nightly
The price is $101
Dec 15 - Dec 16
Total with taxes and fees
SpringHill Suites by Marriott Panama City Beach Beachfront

Hilton Garden Inn Panama City Airport

Hilton Garden Inn Panama City Airport
3.0 star property
Panama City
9.4 out of 10, Exceptional, (671)
"Food is great people are very friendly and helpful "
United States
Stephanie
$100 nightly
The price is $107
Jan 1 - Jan 2, 2026
Total with taxes and fees
Hilton Garden Inn Panama City Airport

Holiday Inn Express & Suites Panama City Beach - Beachfront by IHG

Holiday Inn Express & Suites Panama City Beach - Beachfront by IHG
3.0 star property
Panama City Beach
9.4 out of 10, Exceptional, (1138)
"Beautiful, great value, amazing free breakfast "
United States
Eric
$118 nightly
The price is $133
Dec 21 - Dec 22
Total with taxes and fees
Holiday Inn Express & Suites Panama City Beach - Beachfront by IHG
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find out more about Downtown Panama City

Discover top Downtown Panama City attractions

In Downtown Panama City, families and adventure-seekers alike can explore a wealth of activities. Start your day at the Panama City Marina, where you can rent a boat or take a scenic cruise to soak in the beautiful coastal views. Just a short stroll away, the Science and Discovery Center offers interactive exhibits that captivate both kids and adults, making it a perfect educational stop. For those looking to indulge in local culture, the historic district presents a vibrant array of shops and art galleries, showcasing the creativity of local artisans. Enjoy an afternoon at the picturesque Oaks by the Bay Park, featuring winding trails and playgrounds for the children to enjoy while you relax under the shade of towering trees. As the sun sets, head to the renowned Captain Anderson's Restaurant for a memorable dining experience, famous for its fresh seafood and waterfront views. When it comes to accommodations, Downtown Panama City's hotels offer a blend of modern luxury and attentive service, ensuring that every guest feels pampered. Many properties feature spacious family suites, rooftop pools with stunning city views, and easy access to the area's attractions, making your stay both convenient and comfortable.

Top Downtown Panama City Hotel Reviews

Explore a world of travel with Expedia