Photo by JG Morris

Find Vacation Homes in St. Charles County, MO from $139

Compare and save

Start date: Check-in selected.
To Date
End date: Check-out
  • Bundle & Save

    Get more, spend less whenever you see Bundle & Save deals
  • OneKeyCash

    Earn OneKeyCash on all your eligible bookings
  • Upfront pricing

    We are not like the others - we include taxes and fees

Check prices for these dates

In two weeks
In two months
In three months
In four months

Top Cities in St. Charles County

Vacation Homes in St. Charles County

Stunning 1890's Home - Sleeps 8!

St. Charles Historic District
10.0 out of 10, Exceptional, (99)
"Check-in was easy and the house was lovely "
United States
Delfino A.
$314 nightly
The price is $320
Dec 23 - Dec 24
Total with taxes and fees
Stunning 1890's Home - Sleeps 8!

Cozy Studio Cottage on "The Hill," walkably close to everything! The Zoo, Park!!

The Hill
9.8 out of 10, Exceptional, (160)
"Very clean, check in was easy, great neighborhood with lots of food close. "
United States
Laura H.
$136 nightly
The price is $139
Dec 9 - Dec 10
Total with taxes and fees
Cozy Studio Cottage on "The Hill," walkably close to everything! The Zoo, Park!!

Centrally located in the Tower Grove East neighborhood!

Tower Grove East
9.8 out of 10, Exceptional, (136)
"Very cute property in historic neighborhood. We enjoyed our stay!"
United States
Jo L.
$143 nightly
The price is $168
Dec 9 - Dec 10
Total with taxes and fees
Centrally located in the Tower Grove East neighborhood!

Private House - Sleeps 8 - 13 Min to Downtown STL

Caseyville
9.6 out of 10, Exceptional, (10)
"Very clean and quiet house to spend the weekend in! "
United States
Drew S.
Private House - Sleeps 8 - 13 Min to Downtown STL

Home Near Main Street-Covered Patio-Hot Tub!

Saint Charles
9.8 out of 10, Exceptional, (26)
"The place was great! "
United States
Melissa I.
$468 nightly
The price is $478
Dec 9 - Dec 10
Total with taxes and fees
Home Near Main Street-Covered Patio-Hot Tub!

Entire 4BR Home near Lafayette Square

The Gate
9.8 out of 10, Exceptional, (85)
"What a great stay! We had everything we needed and the owners even went out of their way to accommodate an easier way to get into the house for a family member who had a recent surgery. "
United States
Linda L.
$284 nightly
The price is $294
Dec 21 - Dec 22
Total with taxes and fees
Entire 4BR Home near Lafayette Square

Charming Escape in Grafton!

Grafton
10.0 out of 10, Exceptional, (22)
"The house is wonderful! Clean, modern and close to everything! Wonderful little town. "
United States
Tabbatha H.
Charming Escape in Grafton!

Honky Tonk Hideaway

St. Charles Historic District
8.8 out of 10, Excellent, (12)
"Great location close to historic district."
United States
Hugh S.
$279 nightly
The price is $285
Dec 11 - Dec 12
Total with taxes and fees
Honky Tonk Hideaway

Artsy Creative Haven Home St. Louis Art District

Grand Center
9.8 out of 10, Exceptional, (6)
"This was a really nice place that’s just a few minutes away from every attraction and restaurant we wanted to visit. Plenty of room and beds for a large crowd. We liked that there private off the street parking, too."
United States
Randy M.
Artsy Creative Haven Home St. Louis Art District

Tamm Ave 3-BR Retreat

Dogtown
9.6 out of 10, Exceptional, (48)
"The host was amazing with communication and checking in on how things were going. Property is in a good location and not too far from major attractions. Street of residence is a pretty narrow two way street so vehicles larger than a sedan may have some challenges coming and going. Overall a nice, quiet place to stay!"
United States
Yashika T.
Tamm Ave 3-BR Retreat

Entire Dogtown House near Zoo, Forest Park and Wash U

Dogtown
10.0 out of 10, Exceptional, (221)
"The house was amazing and very clean "
United States
John
Entire Dogtown House near Zoo, Forest Park and Wash U

Escape the city to quiet and picturesque Golden Eagle, IL..

Golden Eagle
10.0 out of 10, Exceptional, (361)
"Another great stay at the Barn for us. I highly recommend the Barn! Great hosts, very clean and comfortable and the rolling hills is such a view! "
United States
Jeremy T.
Escape the city to quiet and picturesque Golden Eagle, IL..

Urban Oasis in the Heart of St. Louis

Carondelet
10.0 out of 10, Exceptional, (3)
"Great stay. All of the amenities and very comfortable. Loved all the personal touches. Thank you, Daniel! "
United States
Lillie H.
Urban Oasis in the Heart of St. Louis

Historic luxury retreat

Lafayette Square
9.8 out of 10, Exceptional, (162)
"Excellent spot for a family trip to St Louis. Great location and very responsive to all needs!!"
United States
Liz S.
Historic luxury retreat

Guest House 632 Summit Street

Alton
10.0 out of 10, Exceptional, (202)
"Beautiful historic home! Fantastic location with amazing views! Very clean with all the amenities needed for a great stay. "
United States
Jessica W.
Guest House 632 Summit Street

Historic Walkable Location! 3BR Home

Benton Park
9.8 out of 10, Exceptional, (30)
"Great location, a little musty older home but with a lot of modern additions. Host was very nice and helpful.Overall nice experience and I would stay there again. "
United States
Mary E R.
Historic Walkable Location! 3BR Home

Modern Downtown Getaway w/ Yard & Grill

Shaw
10.0 out of 10, Exceptional, (67)
"Fabulous location with all amenities. Would stay there again. Many Thanks. "
United States
Marion W.
Modern Downtown Getaway w/ Yard & Grill

Stunning Lakeside Retreat at Innsbrook w/ Swing, Canoe and 3 Kayaks

Wright City
10.0 out of 10, Exceptional, (55)
"Second time staying here, the family of 11 finds it very accommodating for everyone."
United States
Ruth Anne F.
Stunning Lakeside Retreat at Innsbrook w/ Swing, Canoe and 3 Kayaks

Tower Grove -near restaurants & Park- crib, highchair, & fenced back yard

Tower Grove South
9.8 out of 10, Exceptional, (13)
"I enjoyed the stay!"
United States
Rhonda J.
Tower Grove -near restaurants & Park- crib, highchair, & fenced back yard

Pet Friendly 3-bedroom house in Pacific

2.0 star property
Pacific
8.0 out of 10, Very Good, (1)
$331 nightly
The price is $331
Dec 9 - Dec 10
Total with taxes and fees
Pet Friendly 3-bedroom house in Pacific
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Save an average of 15% on thousands of hotels when you're signed in

Top St. Charles County Hotel Reviews

Find out more about St. Charles County

Booking Tips to Find the Best St. Charles County Vacation Homes


How much does it cost to rent a vacation home in St. Charles County?

You can find incredible St. Charles County vacation homes for all types of budgets: between $139 and $478 per night. The more amenities the rental has, and its proximity to popular places, the higher the price.


What is the best time to stay in a vacation home in St. Charles County?

If you are looking for a great deal on your vacation home in St. Charles County, consider visiting in , when prices are usually cheaper.


How many vacation homes are available for rent in St. Charles County?

There are 693 rental houses to choose from for your trip. You’ll find holiday homes located throughout the city, near sightseeing spots, and close to local nature areas.


How do I find the best deal for a vacation home in St. Charles County?

Begin by entering your trip dates to see what type of St. Charles County rental houses are available. Use the map to zoom closer into the areas or zoom out to include more locations. Use the filters on the left side of your search results to narrow down by star rating, price, number of bedrooms, amenities, and more—Expedia makes it easy to score the best deal for your budget.


Why should I rent a vacation home in St. Charles County?

Booking St. Charles County vacation home rentals is the perfect way to spend a vacation because of the privacy, variety of amenities, and comfort you’ll have in your own space.


What amenities are available in a private vacation home?

When thinking about what you want in your St. Charles County rental house, dream big! Depending on your budget and the area, you’ll find amenities like a private pool, hot tub, free parking, fully-equipped kitchen, in-home washer and dryer, Wi-Fi, and a beautiful view or easy access to local sightseeing spots. You can even filter your search results by accessibility to ensure that everyone in your party will be comfortable.


Why should I book a vacation home with Expedia?

Expedia has some of the best selection and deals on available vacation homes in the area—and all in one place. We reward you with members points back on every booking and ensure you get the right accommodation for the best price. And you’ll save big when you bundle your travel together, like booking a car rental in St. Charles County along with your vacation property, into a St. Charles County vacation package.


Can I cancel my vacation home with Expedia?

Some accommodations are free to cancel and refundable if done so by a specific date, while others may be non-refundable. To make sure that you can get your money back on cancellations, use the “free cancellation” filter during your search. Contact our customer service portal if you need help.

St. Charles County Vacation Homes information

Number of reviews
1,665
Accommodation
693 Vacation Homes
Lowest Price
$139
Highest Price
$478

Explore a world of travel with Expedia