Vacation Rentals in St. Charles County

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Top Cities in St. Charles County

Our top choices for St. Charles County vacation rentals

Adorable Augusta Cabin

Adorable Augusta Cabin
Augusta
8.4 out of 10, Very Good, (18 reviews)
"We only stayed one day and did not spend a whole lot of time in the cabin, but it was quaint and comfortable. In a perfect world it would have been priced a bit less (since it was the off season for wine country) but we enjoyed it either way."
United States
Doug S.
$200 nightly
The price is $223
May 14 - May 15
Total with taxes and fees
Adorable Augusta Cabin

Rustic Augusta Wood Cabin

Rustic Augusta Wood Cabin
Augusta
9.6 out of 10, Exceptional, (7 reviews)
"I booked this place wit spend some homely time with my kids and it was amazing, the place was clean they even dropped off some extra towels without us having to ask, it was truly amazing. Will definitely stay there again. "
United States
teresa s.
$286 nightly
The price is $319
May 14 - May 15
Total with taxes and fees
Rustic Augusta Wood Cabin

Spacious 2 Bedroom Townhome

Spacious 2 Bedroom Townhome
Saint Charles
8.2 out of 10, Very Good, (15 reviews)
"This property was perfect for our needs. We enjoyed our stay and thank you for a seamless transaction! Much appreciated!"
United States
Elizabeth
$259 nightly
The price is $285
May 14 - May 15
Total with taxes and fees
Spacious 2 Bedroom Townhome

WELCOME TO THE OWL'S NEST - 2 BEDROOM HOME IN AUGUSTA, WINERIES & THE KATY TRAIL

WELCOME TO THE OWL'S NEST - 2 BEDROOM HOME IN AUGUSTA, WINERIES & THE KATY TRAIL
Augusta
10.0 out of 10, Exceptional, (32 reviews)
"Adorable place to stay!"
United States
Amy F.
$274 nightly
The price is $292
May 14 - May 15
Total with taxes and fees
WELCOME TO THE OWL'S NEST - 2 BEDROOM HOME IN AUGUSTA, WINERIES & THE KATY TRAIL

The Blake Cottage Wine Country Home

The Blake Cottage Wine Country Home
Augusta
8.2 out of 10, Very Good, (10 reviews)
"It was a wonderful location for our girls' night! Plenty of room for our group and within walking distance of the wineries. "
United States
Deana T.
$357 nightly
The price is $398
May 14 - May 15
Total with taxes and fees
The Blake Cottage Wine Country Home

Walk to St. Charles Entertainment

Walk to St. Charles Entertainment
Saint Charles
9.0 out of 10, Wonderful, (10 reviews)
"We really enjoyed our stay. The house was clean, spacious, and very accommodating. We stayed for a dance competition and the proximity to the convention center was unbeatable. "
United States
Chloe
$277 nightly
The price is $305
May 17 - May 18
Total with taxes and fees
Walk to St. Charles Entertainment

Stay on Main Historic Studio

Stay on Main Historic Studio
St. Charles Historic District
9.0 out of 10, Wonderful, (34 reviews)
"From the welcome email with clear concise directions on how to enter with door codes to a dwelling that had everything I needed with a very comfortable bed, it was a great stay and I wanted for nothing."
United States
Jacob G.
$196 nightly
The price is $216
May 18 - May 19
Total with taxes and fees
Stay on Main Historic Studio

Duplex Hideaway in St. Charles, MO

Duplex Hideaway in St. Charles, MO
St. Charles Historic District
10.0 out of 10, Exceptional, (5 reviews)
"I will stay here again. It was a great location for my visit. Lots of room and amenities. Highly recommend this location if you are visiting the St Louis area. Barely a mile to get to Hwy 70, so easy access to St Louis, St Peter's, Wentzville etc. Maybe two blocks from Historic St Charles and Ameristar Casino."
United States
Karen M.
$243 nightly
The price is $268
May 17 - May 18
Total with taxes and fees
Duplex Hideaway in St. Charles, MO

Aunt Doodle’s House 8 blocks from Historic Main Street.. Convenient location!

Aunt Doodle’s House 8 blocks from Historic Main Street.. Convenient location!
St. Charles Historic District
9.6 out of 10, Exceptional, (76 reviews)
"Great communication from host, cute house in an awesome location. Will definitely be staying again!"
United States
Sydney W.
$228 nightly
The price is $244
May 25 - May 26
Total with taxes and fees
Aunt Doodle’s House 8 blocks from Historic Main Street.. Convenient location!

Amazing Renovated Historic Loft on Main Street

Amazing Renovated Historic Loft on Main Street
St. Charles Historic District
10.0 out of 10, Exceptional, (59 reviews)
"Lovely accommodations, very clean, well equipped, great location. "
United States
Emily B.
$258 nightly
The price is $276
May 14 - May 15
Total with taxes and fees
Amazing Renovated Historic Loft on Main Street

Romantic Augusta Cottage w/ hot tub

Romantic Augusta Cottage w/ hot tub
Augusta
9.8 out of 10, Exceptional, (40 reviews)
"Great little place. Nice and relaxing!"
United States
Chris R.
$296 nightly
The price is $312
May 20 - May 21
Total with taxes and fees
Romantic Augusta Cottage w/ hot tub

The Lofts of North Main Street

The Lofts of North Main Street
St. Charles Historic District
9.6 out of 10, Exceptional, (169 reviews)
"Host was very responsive and location was perfect"
United States
Peggy K.
$242 nightly
The price is $259
May 20 - May 21
Total with taxes and fees
The Lofts of North Main Street

Charming open 4bd and screen-in porch! Sleeps 10!

Charming open 4bd and screen-in porch! Sleeps 10!
Saint Charles
9.2 out of 10, Wonderful, (39 reviews)
"House had everything we needed, and was very well organized! Would definitely recommend!"
United States
Tim W.
$443 nightly
The price is $501
May 18 - May 19
Total with taxes and fees
Charming open 4bd and screen-in porch! Sleeps 10!

Cozy 3 Bedroom/ Family Comfort & Convenient Location

Cozy 3 Bedroom/ Family Comfort & Convenient Location
Wentzville
10.0 out of 10, Exceptional, (4 reviews)
"It was a very comfortable place to stay."
United States
Vickie M.
$331 nightly
The price is $356
May 20 - May 21
Total with taxes and fees
Cozy 3 Bedroom/ Family Comfort & Convenient Location

Cottage on Main st- Low Cleaning Fee

Cottage on Main st- Low Cleaning Fee
St. Charles Historic District
10.0 out of 10, Exceptional, (8 reviews)
"Good location. Decorated very nicely. "
United States
Debbie A.
$274 nightly
The price is $293
May 18 - May 19
Total with taxes and fees
Cottage on Main st- Low Cleaning Fee

Historic 1908 Frenchtown Home

Historic 1908 Frenchtown Home
St. Charles Historic District
8.6 out of 10, Excellent, (20 reviews)
"Very clean, older 2-bedroom home. Close to all the Main Street action. House had all the amenities we needed."
United States
Michele S.
$302 nightly
The price is $332
Jun 1 - Jun 2
Total with taxes and fees
Historic 1908 Frenchtown Home

Historic Main St. Customs House Upstairs Apartment

Historic Main St. Customs House Upstairs Apartment
St. Charles Historic District
9.6 out of 10, Exceptional, (37 reviews)
"Lovely place to stay!"
United States
Margaret A.
$340 nightly
The price is $375
May 17 - May 18
Total with taxes and fees
Historic Main St. Customs House Upstairs Apartment

The Historic Bricks on Main

The Historic Bricks on Main
St. Charles Historic District
9.0 out of 10, Wonderful, (17 reviews)
"Had a wonderful stay. Host was very responsive. Great stay in the middle of everything- so we could walk out and shop or grab a bite to eat. "
United States
Alison C.
$245 nightly
The price is $269
May 31 - Jun 1
Total with taxes and fees
The Historic Bricks on Main

Prime Loft of Main Street

Prime Loft of Main Street
St. Charles Historic District
9.8 out of 10, Exceptional, (110 reviews)
"This was a wonderful place for our St Charles stay - right in the heart of the historic downtown. Very clean and with nice character (exposed brick walls, tastefully decorated, etc). We had plenty of room fo the three of us, and our almost 12 year old kiddo LOVED having the loft upstairs to herself. If you are looking for a place to stay outside of St Louis, I highly recommend this location."
United States
Julie
$258 nightly
The price is $276
May 17 - May 18
Total with taxes and fees
Prime Loft of Main Street

1 Bedroom | Pool & Gym. Free Breakfast

1 Bedroom | Pool & Gym. Free Breakfast
O'Fallon
8.6 out of 10, Excellent, (4 reviews)
"I loved the location of the property. The suite was spacious and cozy. Breakfast options were great."
United States
Barbara A.
$137 nightly
The price is $158
May 27 - May 28
Total with taxes and fees
1 Bedroom | Pool & Gym. Free Breakfast
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top St. Charles County Hotel Reviews

Find out more about St. Charles County

Discover your perfect St. Charles County vacation rental with Expedia

How many vacation rentals are available in St. Charles County?


Expedia has plenty of vacation rentals to choose from in and around  St. Charles County, so you’re guaranteed to find the right one for you. 


How much is a vacation rental in St. Charles County?


The selection of St. Charles County vacation rentals we have selected for you start as low as $120 per night. Entering your travel dates in the search wizard you might find even better deals!


What type of vacation rental can I get in St. Charles County?


Vacation rentals in St. Charles County come in all shapes and sizes, and your options depend on your chosen travel dates. You could entertain in a blissful vacation home, chill in a private apartment, or find family fun at a resort. Expedia offers a superb choice of St. Charles County vacation rentals to suit everyone. 


Why should I choose a vacation rental in St. Charles County?


Expedia’s vacation rentals provide cozy comforts you can sink into on your own schedule. You’ll enjoy your own space in a property with a kitchen, a pool, a garden etc. Maybe you’ll prefer somewhere with a spa or kids activities. A St. Charles County vacation rental often works out to be a fantastic, cost-effective option for groups and families visiting for a few nights or longer. And if a hotel room is just too small, get a vacation rental with multiple bedrooms and shared living spaces to kick back in. 


How do I find the best deal on a vacation rental in St. Charles County?


Find vacation rentals in St. Charles County by viewing Expedia’s latest deals, or enter your travel dates and use the filters to select by amenities, price, or rating. Dive into the reviews to get a true feeling of which is your favorite vacation rental in St. Charles County.  


What amenities are available in a vacation rental in St. Charles County?


The choice is yours! Perhaps you love cooking in a well-equipped kitchen. Or maybe a late breakfast and a swimming pool is more your thing. Of course, there’s always the treat of having your own hot tub. Expedia has a vast range of amenities in St. Charles County vacation rentals designed to suit every budget and trip type.


When is the best time to stay in a vacation rental in St. Charles County?   


Everytime is a great time to head to St. Charles County! Staying in a St. Charles County vacation rentals you will always find lots going on to keep you entertained. 


Why book a vacation rental with Expedia?


Expedia has locked in amazing deals on a huge selection of impressive vacation rentals in St. Charles County. We give you the information and inspiration you need all in one place. With so many properties to choose from, you know you can book your perfect St. Charles County vacation rental with confidence. ANd don’t forget, if you bundle with a flight or a car rental in St. Charles County, you can save even more.


Can I cancel my vacation rental through Expedia?  


Yes, you can cancel or change your St. Charles County vacation rental by contacting your property manager directly. Contact details are easy to find on your itinerary in Trips. For more information, check out our Customer Service Portal and we’ll help you get everything sorted.