Title: Depew Vacation Packages 2026 from $282 | Expedia.com [Depew Travel Guide](https://expedia.com/Depew.dx6338362)[Hotels in Depew](https://expedia.com/Depew-Hotels.d6338362.Travel-Guide-Hotels)[Vacation Rentals in Depew](https://expedia.com/Depew-Vacation-Rentals.d6338362.Travel-Guide-VacationRentals)[Flights to Depew](https://expedia.com/Cheap-Flights-To-Depew.d6338362.Travel-Guide-Flights)[Things to do in Depew](https://expedia.com/Things-To-Do-In-Depew.d6338362.Travel-Guide-Activities)[Car Rentals in Depew](https://expedia.com/Car-Rentals-In-Depew.d6338362.Car-Rental-Guide) ![](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_packages.jpeg?impolicy=fcrop&w=1200&h=300&q=medium) # Depew Vacations from $282 ## Book a Hotel + Flight or Car together to unlock savings - ## Plan, book, travel with confidence - ### Better together Save up to $1,045 when you book a flight and hotel together\* - ### Find the right fit With over 300,000 hotels worldwide, it's easy to create a perfect package - ### Rest easy Plan, book, and manage your trip all in one place ## Your Depew Vacation A great way to experience this interesting city is with a customized Depew vacation package. Base yourself in the neighborhood of Downtown Buffalo, which is great for nightlife, shopping and bars and pubs or choose someplace else β€” our packages are all about you. Make your trip to Depew even more fulfilling by going sightseeing. [Walden Galleria Mall](https://www.expedia.com/Walden-Galleria-Mall-Buffalo.d6129205.Vacation-Attraction), [Holiday Twin Rinks](https://www.expedia.com/Holiday-Twin-Rinks-Buffalo.d6207411.Vacation-Attraction) and [Eastern Hills Mall](https://www.expedia.com/Eastern-Hills-Mall-Harris-Hill.d6129207.Vacation-Attraction) are some of the popular attractions you'll want to explore. Whoever you're taking time off with and whatever your bank balance, your ultimate Depew vacation is just clicks away with Expedia. ## The Latest Depew vacation packages Price found within the past 48 hours. Click for updated prices. ![Buffalo Airport Hotel](https://images.trvl-media.com/lodging/1000000/30000/26100/26001/90223c0d_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Buffalo Airport Hotel $282 per person Apr 17 - Apr 20 found 1 day ago Roundtrip flight included Atlanta (ATL) to Buffalo (BUF) 8/10 Very Good! (2,709 reviews) Very well located, spacious and clean rooms and very good price. Unfortunately, they do not have breakfast included. Reviewed on Feb 2, 2026 ![The Richardson Hotel](https://images.trvl-media.com/lodging/19000000/18140000/18136300/18136290/16863301_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### The Richardson Hotel Elmwood Bidwell Save 100% on your flight $543 per person Apr 17 - Apr 20 found 1 day ago Roundtrip flight included Atlanta (ATL) to Buffalo (BUF) 9/10 Wonderful! (1,002 reviews) The only real issue was you could only connect to one devise at a time for WiFi. Room was spotless, staff were very nice Reviewed on Feb 3, 2026 ![The Mansion On Delaware Ave](https://images.trvl-media.com/lodging/1000000/700000/692700/692610/1225a495_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### The Mansion On Delaware Ave Downtown Buffalo $461 per person Apr 17 - Apr 20 found 1 day ago Roundtrip flight included Atlanta (ATL) to Buffalo (BUF) 9.4/10 Exceptional! (1,002 reviews) Room upgrade. Pleasant staff. Reviewed on Feb 3, 2026 ![M Hotel Buffalo](https://images.trvl-media.com/lodging/1000000/20000/11300/11231/2c4d5593_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### M Hotel Buffalo $360 per person Apr 17 - Apr 20 found 1 day ago Roundtrip flight included Atlanta (ATL) to Buffalo (BUF) 7.4/10 Good! (2,426 reviews) Nice rooms but outdated Reviewed on Jan 25, 2026 ![Holiday Inn Express Grand Island - Niagara Falls by IHG](https://images.trvl-media.com/lodging/19000000/18570000/18567300/18567279/50c6a12d_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Holiday Inn Express Grand Island - Niagara Falls by IHG $556 per person Apr 30 - May 4 found 1 day ago Roundtrip non-stop flight included San Juan (SJU) to Buffalo (BUF) 8.8/10 Excellent! (1,542 reviews) Spacious, clean room. Brand new building. Excellent front desk service. Delicious breakfast. What more do you want? Reviewed on Feb 5, 2026 Don't see what you're looking for? See all available trips from Columbus to Depew [View all trips](https://expedia.com/go/package/search/FlightHotel/2026-03-05/2026-03-12/?FromAirport=Columbus,%20Ohio,%20United%20States%20of%20America&Destination=BUF&NumRoom=1&NumAdult=2&NumChild=0&paandie=true) ### Discover the most popular places to visit in Depew ![A beautiful sunset today at ub! At least there is one perk to being stuck on campus for 12 hours! πŸŒ…πŸŒ…πŸŒ… #ub #universityatbuffalo #buffalo #sunset #baridpoint #oozefestpits #springsemester #academicspine #campuslife ](https://images.trvl-media.com/place/6276889/6f4929dc-5220-42a3-b540-54ed4dcc34d4.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### University At Buffalo - North Campus Enjoy the collegiate vibe when you visit University At Buffalo - North Campus, during your trip to Amherst. Experience the area's acclaimed theater scene and great live music. [](https://expedia.com/University-At-Buffalo-North-Campus-Buffalo.d6175369.Vacation-Attraction) ![Downtown Buffalo NY](https://images.trvl-media.com/place/6064435/ddc94cc9-ad1a-4fc7-b3a1-f2ba87b4fb62.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### KeyBank Center Catch an event at KeyBank Center during your trip to Buffalo. Experience the area's great live music and acclaimed theater scene. [](https://expedia.com/KeyBank-Center-Buffalo.d6064435.Vacation-Attraction) ![NFL Salute to Service Buffalo Bills Ralph Wilson Stadium](https://images.trvl-media.com/place/6047844/967ffd8d-0ce5-4803-b2a8-0405cc2eb554.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Highmark Stadium Catch an event at Highmark Stadium during your trip to Orchard Park. Experience the area's entertainment choices and great live music. [](https://expedia.com/Highmark-Stadium-Buffalo.d6058007.Vacation-Attraction) ### What to do in Depew ![TR is waiting to greet you!](https://mediaim.expedia.com/localexpert/672820/ce030e1b-f8b5-41d2-a399-b3942bfe2fd7.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Theodore Roosevelt Inaugural National Historic Site Admission and Guided Tour $13 per adult **100%** of travellers recommend [](https://expedia.com/things-to-do/theodore-roosevelt-inaugural-national-historic-site-admission-and-guided-tour.a672820.activity-details) ![Buffalo Sabres Ice Hockey Game at Keybank Center](https://mediaim.expedia.com/localexpert/47587364/44132dfb-c136-4b5b-a87d-50293ca8e949.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Buffalo Sabres Ice Hockey Game at Keybank Center $94 per adult [](https://expedia.com/things-to-do/buffalo-sabres-ice-hockey-game-at-keybank-center.a47587364.activity-details) ![Niagara Falls Self-Guided Driving Audio Tour from Toronto](https://mediaim.expedia.com/localexpert/49289256/11eb9a03-8a54-418e-b42b-71b7c5463267.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Niagara Falls Self-Guided Driving Audio Tour from Toronto $17 per traveler [](https://expedia.com/things-to-do/niagara-falls-self-guided-driving-audio-tour-from-toronto.a49289256.activity-details) [See all activities in Depew](https://expedia.com/things-to-do/search?rid=6338362) ## Depew Hotel Deals ![Buffalo Airport Hotel](https://images.trvl-media.com/lodging/1000000/30000/26100/26001/90223c0d_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Buffalo Airport Hotel 4600 Genesee St Buffalo NY Fully refundableReserve now, pay when you stay $90 nightly $102 total Feb 8 - Feb 9 Total with taxes and fees 7.8/10 Good! (2,878 reviews) Very well located, spacious and clean rooms and very good price. Unfortunately, they do not have breakfast included. Reviewed on Feb 2, 2026 [](https://expedia.com/Hotel-Search?startDate=2%2F8%2F2026&endDate=2%2F9%2F2026&selected=26001&PinnedHotelID=26001&HadPinnedHotel=true®ionId=6338362) ![Garden Place Hotel](https://images.trvl-media.com/lodging/2000000/1070000/1060800/1060721/40afc3e4_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Garden Place Hotel 6615 Transit Road Buffalo NY Fully refundableReserve now, pay when you stay $95 nightly $108 total Feb 8 - Feb 9 Total with taxes and fees 7.6/10 Good! (2,237 reviews) Great front staff Reviewed on Jan 30, 2026 [](https://expedia.com/Hotel-Search?startDate=2%2F8%2F2026&endDate=2%2F9%2F2026&selected=1060721&PinnedHotelID=1060721&HadPinnedHotel=true®ionId=6338362) ![Hyatt Regency Buffalo / Hotel and Conference Center](https://images.trvl-media.com/lodging/1000000/30000/23200/23101/00561234_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Hyatt Regency Buffalo / Hotel and Conference Center Two Fountain Plaza Buffalo NY Fully refundableReserve now, pay when you stay $143 nightly $167 total Feb 9 - Feb 10 Total with taxes and fees 8/10 Very Good! (1,739 reviews) Need express check in option. Breakfast is way too expensive. If you're going to charge that much, at least have staff that serves me. Buffett is not acceptable at that price. Reviewed on Feb 2, 2026 [](https://expedia.com/Hotel-Search?startDate=2%2F9%2F2026&endDate=2%2F10%2F2026&selected=23101&PinnedHotelID=23101&HadPinnedHotel=true®ionId=6338362) [See all 880 properties in Depew](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.Package&startDate=2%2F6%2F2026&endDate=2%2F7%2F2026®ionId=6338362) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. ## Find the Best Depew Vacation Packages ## Depew Essential Information | Language | English | | --------------- | -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- | | Currency | U.S dollars | | Closest Airport | Buffalo Niagara Intl. Airport (BUF) | | Population | 15,100 | | Max Temp Winter | 30ΒΊF | | Max Temp Summer | 75ΒΊF | | Top Sights | [Buffalo Zoo](https://www.expedia.com/Buffalo-Zoo-North-Buffalo.d6064383.Vacation-Attraction), [Buffalo Museum of Science](https://www.expedia.com/Buffalo-Museum-Of-Science-Buffalo.d6064413.Vacation-Attraction) and [Albright - Knox Art Gallery](https://www.expedia.com/Albright-Knox-Art-Gallery-North-Buffalo.d6064379.Vacation-Attraction) | ## More vacations you might like ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/06/08/all-inclusive_holidays_US.jpeg?impolicy=fcrop&w=300&h=300&q=mediumHigh) All Inclusive Vacations [](https://expedia.com/lp/theme-vacations/all-inclusive-vacations?rfrr=editorial.All_Inclusive%20Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/10/17/XPC_Beach_Overview_HR_v3.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Beach Vacations 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[](https://expedia.com/lp/theme-vacations/adventure-vacations?rfrr=editorial.Adventure_Vacations.click) ![Vacations in Month](https://forever.travel-assets.com/flex/flexmanager/images/2023/05/10/mesog-34434-card-venice.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Where to go when [](https://expedia.com/lp/b/where-to-go-when?rfrr=editorial.Where_to%20go%20when.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2024/05/21/honeymoon_hawaii.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Honeymoon Vacations [](https://expedia.com/lp/theme-vacations/honeymoon-vacations?rfrr=editorial.Honeymoon_Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2024/05/23/Mountain-vacations.jpeg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Mountain Vacations [](https://expedia.com/lp/theme-vacations/mountain-vacations?rfrr=editorial.Mountain_Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2024/05/23/fishing-vacations-2.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Fishing Vacations [](https://expedia.com/lp/theme-vacations/fishing-vacations?rfrr=editorial.Fishing_Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2019/05/16/Hyatt%20Zilara%20Cancun%20-%20All%20Inclusive%20-%20Adults%20Only.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Adults Only Vacations [](https://expedia.com/lp/theme-vacations/adults-only-vacations?rfrr=editorial.Adults_Only%20Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2024/05/23/waterpark-vacations.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Waterpark Vacations [](https://expedia.com/lp/theme-vacations/waterpark-vacations?rfrr=editorial.Waterpark_Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2024/05/08/Caribean_scuba_diving.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Scuba Diving Vacations [](https://expedia.com/lp/theme-vacations/scuba-diving-vacations?rfrr=editorial.Scuba_Diving%20Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2024/05/08/aruba_yoga.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Yoga Vacations [](https://expedia.com/lp/theme-vacations/yoga-vacations?rfrr=editorial.Yoga_Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2023/04/04/EPS-RBC-SummerBeachVacations-AdobeStock_206356322.jpeg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Cheap Vacations [](https://expedia.com/lp/theme-vacations/cheap-vacations?rfrr=editorial.Cheap_Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2024/06/26/1175883311.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Solo Vacations [](https://expedia.com/lp/b/vacations/solo-vacations?rfrr=editorial.Solo_Vacations.click) ## Frequently asked questions ### How much does a Depew vacation package cost? ### What are the cheapest months to go to Depew? ### How many days is enough for Depew? ### How to find the best Depew package deals? ### Is it cheaper to book a Depew vacation as a package? ### When to book a vacation package to Depew? ### How to plan a trip to Depew? > 1. Choose when to get away: Check your schedule and get your bags packed. Your preferred time of year and the type of activities available will also help you decide when to escape to Depew. > 2. Plan your budget wisely: On top of the cost of your accommodations, you should factor in other expenses too. These include flights, food and transportation. Also, set aside some extra funds for unexpected costs that may crop up during your trip to Depew. > 3. Organize your Depew escape with our [trip planning tool](https://www.expedia.com/why/trip-planning): Look for and book accommodations and experiences all in one place. You can also collaborate with your group to plan an unforgettable trip to Depew together. > 4. Decide how many days away: Start by compiling a list of the attractions you'd like to get to in Depew. Then, estimate how long you'll need at each, as well as any travel time. > 5. Combine your flights and hotel: Awesome destination, check. Length of stay, check. All that's left is to choose a Depew vacation package that brings all your bookings together. > 6. Book any day trips or activities: Here's the fun part β€” organizing everything you want to see and do. Check out some of the top [things to do in Depew](https://www.expedia.com/Things-To-Do-In-Depew.d6338362.Travel-Guide-Activities) in Depew and reserve your tickets early to save time (and maybe some money too!). ### Does Expedia offer Book Now, Pay Later Depew vacation packages? \* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages. ![](https://a.travel-assets.com/mad-service/footer/bnaBanners/BEX_Footer.jpg) ## Go further with the Expedia app Save even more - get up to 20% on select hotels when you book on the app. Our app deals help you to save on trips so you can travel more and manage it all on the go. Scan the QR code with your device camera and download our app