Depew Vacation Rentals

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Our top choices for Depew vacation rentals

3-bedroom house in close to the airport Buffalo family- friendly no pets allowed

3-bedroom house in close to the airport Buffalo family- friendly no pets allowed
Depew
2.0 out of 10, (1 review)
"Host super disrespectful "
United States
Celeste J.
$239 nightly
The price is $267
May 7 - May 8
Total with taxes and fees
3-bedroom house in close to the airport Buffalo family- friendly no pets allowed

Tiny Spa Cottage Retreat

Tiny Spa Cottage Retreat
Alden
9.8 out of 10, Exceptional, (117 reviews)
"Excllent, clean and cozy space to spend the night!"
United States
John A.
$182 nightly
The price is $203
May 7 - May 8
Total with taxes and fees
Tiny Spa Cottage Retreat

Cozy Cuddler's Cottage

Cozy Cuddler's Cottage
West Falls
9.8 out of 10, Exceptional, (7 reviews)
"This was a perfect place for our family to stay for the weekend and the owner was so helpful!!"
United States
Nicole H.
$226 nightly
The price is $253
May 7 - May 8
Total with taxes and fees
Cozy Cuddler's Cottage

Luxury Villa

Luxury Villa
Lancaster
9.8 out of 10, Exceptional, (11 reviews)
"Really enjoyed my stay! They made us very comfortable and let us check in early due to our early flight 10/10 come check it out "
United States
Da’Lisha P.
$143 nightly
The price is $160
May 11 - May 12
Total with taxes and fees
Luxury Villa

Don’t miss out on the opportunity to stay in the 12thManMisfitzManor

Don’t miss out on the opportunity to stay in the 12thManMisfitzManor
Orchard Park
9.8 out of 10, Exceptional, (28 reviews)
"Such a fun spot! "
United States
Jamie F.
$233 nightly
The price is $260
May 20 - May 21
Total with taxes and fees
Don’t miss out on the opportunity to stay in the 12thManMisfitzManor

Spacious kid friendly apt near East Aurora

Spacious kid friendly apt near East Aurora
West Falls
10.0 out of 10, Exceptional, (10 reviews)
"Great stay in a great location. "
United States
Anonymous traveler
$254 nightly
The price is $284
May 11 - May 12
Total with taxes and fees
Spacious kid friendly apt near East Aurora

Whimsical Yurt near Niagara Falls and Buffalo

Whimsical Yurt near Niagara Falls and Buffalo
Tonawanda
10.0 out of 10, Exceptional, (63 reviews)
"Love staying here….Have booked it 2x and never disappointed…close to everything you need "
United States
Melisa R.
$198 nightly
The price is $221
May 14 - May 15
Total with taxes and fees
Whimsical Yurt near Niagara Falls and Buffalo

Peaceful one bedroom in university district

Peaceful one bedroom in university district
University Heights
8.8 out of 10, Excellent, (5 reviews)
"Quick weekend up in Buffalo. This place got the job done. Good size and the host was great!"
United States
Brandon W.
$145 nightly
The price is $166
May 7 - May 8
Total with taxes and fees
Peaceful one bedroom in university district

Nice house with king bed 25min to Niagara falls

Nice house with king bed 25min to Niagara falls
Broadway - Fillmore
9.0 out of 10, Wonderful, (28 reviews)
"Very nice stay highly recommend "
United States
Alexander
$256 nightly
The price is $264
May 19 - May 20
Total with taxes and fees
Nice house with king bed 25min to Niagara falls

*Perfect Vacation* Cozy Lancaster Village Bungalow

*Perfect Vacation* Cozy Lancaster Village Bungalow
Lancaster
10.0 out of 10, Exceptional, (1 review)
"No concerns. Everything as stated. "
United States
Ronald F.
$323 nightly
The price is $327
May 7 - May 8
Total with taxes and fees
*Perfect Vacation* Cozy Lancaster Village Bungalow

The Victorian on South Park • Sleeps 6

The Victorian on South Park • Sleeps 6
Triangle
9.0 out of 10, Wonderful, (22 reviews)
"Very clean good location, quiet."
United States
Gail S.
$207 nightly
The price is $238
May 13 - May 14
Total with taxes and fees
The Victorian on South Park • Sleeps 6

Charming 2-bedroom apartment in Pleasant Blasdell with morning breakfast.

Charming 2-bedroom apartment in Pleasant Blasdell with morning breakfast.
Blasdell
9.8 out of 10, Exceptional, (7 reviews)
"The place was fairly clean. Well stocked and the hosts were incredibly nice! "
United States
Matthew
$256 nightly
The price is $286
May 7 - May 8
Total with taxes and fees
Charming 2-bedroom apartment in Pleasant Blasdell with morning breakfast.

11 min from BUF Airport, 19 min from Bills Stadium, 35 min from Niagara Falls!

11 min from BUF Airport, 19 min from Bills Stadium, 35 min from Niagara Falls!
Buffalo
10.0 out of 10, Exceptional, (9 reviews)
"Very clean and accomadating"
United States
Francis c.
$165 nightly
The price is $184
May 7 - May 8
Total with taxes and fees
11 min from BUF Airport, 19 min from Bills Stadium, 35 min from Niagara Falls!

Delightful dwelling

Delightful dwelling
Elmwood Bidwell
10.0 out of 10, Exceptional, (2 reviews)
"The host is very friendly and accommodating. The unit is very nice, private and quite. The neighborhood is safe with resturants and shops within 15 minutes walk. Highly recommend this unit."
United States
Nasser K.
$277 nightly
The price is $317
May 7 - May 8
Total with taxes and fees
Delightful dwelling

Nice house with private parking, king bed fenced yard

Nice house with private parking, king bed fenced yard
West Seneca
8.8 out of 10, Excellent, (10 reviews)
"Yes suitable for pets. Kitchen had what we needed. We very much enjoyed our stay, immaculate condition. "
United States
Sean
$283 nightly
The price is $328
May 26 - May 27
Total with taxes and fees
Nice house with private parking, king bed fenced yard

Niagara Falls, Highmark, Buffalo Vacation House

Niagara Falls, Highmark, Buffalo Vacation House
Cheektowaga
10.0 out of 10, Exceptional, (4 reviews)
"Very affordable and close to everything in buffalo i loved it!!!!"
United States
Hunter
$293 nightly
The price is $327
May 10 - May 11
Total with taxes and fees
Niagara Falls, Highmark, Buffalo Vacation House

Down town Buffalo oasis, 20 minutes from the Niagara Falls

Down town Buffalo oasis, 20 minutes from the Niagara Falls
Downtown Buffalo
10.0 out of 10, Exceptional, (33 reviews)
"We had a great stay at this home in Buffalo. The space was beautifully decorated with thoughtful art pieces throughout, which made it feel warm and inviting. There was plenty of room to spread out, and everything was comfortable and well laid out. We would definitely stay here again and recommend it to others visiting the area, especially with a group!"
United States
Sanja D.
$221 nightly
The price is $254
May 12 - May 13
Total with taxes and fees
Down town Buffalo oasis, 20 minutes from the Niagara Falls

Charming 3-bedroom house in delightful Orchard Park with WiFi, AC

Charming 3-bedroom house in delightful Orchard Park with WiFi, AC
Orchard Park
9.8 out of 10, Exceptional, (21 reviews)
"This was a great place -- the house is very clean and the location is perfect!"
United States
Tony C.
$421 nightly
The price is $470
May 7 - May 8
Total with taxes and fees
Charming 3-bedroom house in delightful Orchard Park with WiFi, AC

2-bedroom House in beautiful Grand Island,NY! 4 miles from Niagara Falls!

2-bedroom House in beautiful Grand Island,NY! 4 miles from Niagara Falls!
Grand island
9.8 out of 10, Exceptional, (17 reviews)
"Accomodations were great"
United States
Ginny A.
$231 nightly
The price is $258
May 10 - May 11
Total with taxes and fees
2-bedroom House in beautiful Grand Island,NY! 4 miles from Niagara Falls!

Brand new furniture with parking

Brand new furniture with parking
West Seneca
9.0 out of 10, Wonderful, (6 reviews)
"Clean rooms and well maintained property"
United States
Sal F.
$310 nightly
The price is $360
May 18 - May 19
Total with taxes and fees
Brand new furniture with parking
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Depew Hotel Reviews

Find out more about Depew

Everything you need to know about Depew vacation rentals

Whether you’re excited for the perfect family vacation, a romantic getaway for two, or the ultimate city break, we’ve got the Depew vacation rental for you. At Expedia, you can take your pick from private vacation homes, apartments, condos, resorts, cabins, villas, motels. The list goes on, and on …and on.

There’s just as wide a choice of amenities, too. Maybe you’re dreaming of your own pool, long evenings in a hot tub, or watching the kids laugh through the day at a waterpark. Maybe you just want a quiet retreat in a pet-friendly apartment. Well, we can help you find it. Hunt out the perfect Depew vacation rental for you by simply entering your desired dates. Then check your favorite filters to narrow down your search.

Depew vacation rentals: An excellent choice for every season

Whenever you want to travel, a warm welcome awaits you in Depew. If you’re looking for a little peace, consider booking during the quieter low season months. For more hustle and bustle, you may prefer to visit Depew in high season.

Prices vary throughout the year. Your chosen location, property type, and amenities will impact the cost of your trip, too. The selection of properties we have chosen for you start as low as $163 per night. Rates vary depending on your travel dates, location, and amenities so make a search and you might find even better deals!

How to find incredible deals on Depew rentals

At Expedia, we put the best Depew vacation rentals in one place. All you need to do is take your pick. And as we offer book now, pay later options, as well as free cancellation on some properties, you can plan your trip with total peace of mind. You’ll always find a great deal with Expedia.

To find some top Depew rental deals, enter your travel dates, and sort your search results by price. You can also filter by budget, so you only see accommodation in your ballpark. Next, add any filters you want—and just like that, you’ve built your dream Depew vacation.

If you’re looking for a little inspiration, browse our latest incredible offers, or use the map to view all accommodation in and around Depew. And to unlock even more fantastic deals, bundle your accommodation, flights, and car rental together to save and book with Expedia in complete confidence.

Frequently asked questions

Can I find vacation rentals in Depew?

Yes, we have vacation rentals near well known sights in Depew, or you can choose a secluded option if you're looking for relaxation. Depew is known for its shopping and restaurants. Make sure you have time to check out the sporting events and waterfalls during your trip.

What are some of the best vacation home rentals in Depew?

3-bedroom house in close to the airport Buffalo family- friendly no pets allowed: Visitors give good reviews to this Depew vacation home rental, which has air-conditioning and laundry facilities to help you feel perfectly comfortable in your new surroundings.

How many vacation rentals will I find in Depew?

Choose from 7 Expedia vacation rentals in Depew for a memorable vacation.

What can I see and do in Depew?

While exploring the area, visit family-friendly sights like Holiday Twin Rinks, or get outside and enjoy nature at Glen Falls. Walden Galleria Mall and Samuel’s Grande Manor are a couple of places you'll find in the larger area.

What are vacation rentals like in Depew?

Vacation rentals are private accommodations you can reserve for several days or more in Depew. Vacation rentals feature extras like WiFi and washers and dryers so you'll have everything you want. If you're concerned about a sanitized environment, a vacation rental can provide a sense of safety away from shared hotel elevators and busy lobbies while still allowing you a great travel experience. You'll also find more space in a vacation rental than in a standard hotel, which makes a vacation rental a great option for a family trip.