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Depew Vacation Rentals

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Our top choices for Depew vacation rentals

Tiny Spa Cottage Retreat

Tiny Spa Cottage Retreat
Alden
9.8 out of 10, Exceptional, (124 reviews)
"Everything about this tiny cottage was perfect. I was looking for a quiet relaxing long weekend away from work & couldnt have asked for more."
United States
MELODY K.
$182 nightly
The price is $203
Jun 21 - Jun 22
Total with taxes and fees
Tiny Spa Cottage Retreat

Studio 6 Buffalo|Cozy 2 Full Beds,Nsmk|Kitchen

Studio 6 Buffalo|Cozy 2 Full Beds,Nsmk|Kitchen
Buffalo NY
10.0 out of 10, Exceptional, (48 reviews)
$93 nightly
The price is $106
Jul 21 - Jul 22
Total with taxes and fees
Studio 6 Buffalo|Cozy 2 Full Beds,Nsmk|Kitchen

Studio 6 Buffalo|1 Queen Bed,Nsmk|Kitchen

Studio 6 Buffalo|1 Queen Bed,Nsmk|Kitchen
Buffalo NY
10.0 out of 10, Exceptional, (43 reviews)
"Good place to stay"
United States
Anonymous traveler
$88 nightly
The price is $100
Jul 13 - Jul 14
Total with taxes and fees
Studio 6 Buffalo|1 Queen Bed,Nsmk|Kitchen

Cozy Cuddler's Cottage

Cozy Cuddler's Cottage
West Falls
9.8 out of 10, Exceptional, (11 reviews)
"Awesome location. Friendly staff. Great value and close to family!!"
United States
Bill
$227 nightly
The price is $254
Jun 25 - Jun 26
Total with taxes and fees
Cozy Cuddler's Cottage

Don’t miss out on the opportunity to stay in the 12thManMisfitzManor

Don’t miss out on the opportunity to stay in the 12thManMisfitzManor
Orchard Park
9.8 out of 10, Exceptional, (29 reviews)
"Such a fun spot! "
United States
Jamie F.
$263 nightly
The price is $294
Jun 22 - Jun 23
Total with taxes and fees
Don’t miss out on the opportunity to stay in the 12thManMisfitzManor

Luxury Villa

Luxury Villa
Lancaster
9.8 out of 10, Exceptional, (16 reviews)
"Really enjoyed my stay! They made us very comfortable and let us check in early due to our early flight 10/10 come check it out "
United States
Da’Lisha P.
$175 nightly
The price is $195
Jun 28 - Jun 29
Total with taxes and fees
Luxury Villa

*Perfect Vacation* Cozy Lancaster Village Bungalow

*Perfect Vacation* Cozy Lancaster Village Bungalow
Lancaster
10.0 out of 10, Exceptional, (1 review)
"No concerns. Everything as stated. "
United States
Ronald F.
$360 nightly
The price is $365
Jun 22 - Jun 23
Total with taxes and fees
*Perfect Vacation* Cozy Lancaster Village Bungalow

Regency Retreat

Regency Retreat
3.0 star property
Lockport
$386 nightly
The price is $437
Jul 2 - Jul 3
Total with taxes and fees
Regency Retreat

Niagara Falls is only 30minutes away.Airport 4 min away. Family & pet friendly!

Niagara Falls is only 30minutes away.Airport 4 min away. Family & pet friendly!
Buffalo
9.8 out of 10, Exceptional, (28 reviews)
"Nice accommodation for the cost with host being responsive with any questions we had along with any requests.We would recommend to anyone and will stay again when in the area."
United States
Aimee R.
$180 nightly
The price is $201
Jun 24 - Jun 25
Total with taxes and fees
Niagara Falls is only 30minutes away.Airport 4 min away. Family & pet friendly!

Spacious kid friendly apt near East Aurora

Spacious kid friendly apt near East Aurora
West Falls
10.0 out of 10, Exceptional, (11 reviews)
"Great stay in a great location. "
United States
Anonymous traveler
$256 nightly
The price is $286
Jun 30 - Jul 1
Total with taxes and fees
Spacious kid friendly apt near East Aurora

420 Friendly 3 bedroom upstairs apartment. Street parking only.

420 Friendly 3 bedroom upstairs apartment. Street parking only.
Seneca
9.4 out of 10, Exceptional, (73 reviews)
"Excellent stay! All the things we needed and then some :) highly recommend! Will be staying here anytime I am in the area!"
United States
Kerry G.
$179 nightly
The price is $182
Jul 8 - Jul 9
Total with taxes and fees
420 Friendly 3 bedroom upstairs apartment. Street parking only.

Delightful dwelling

Delightful dwelling
Elmwood Bidwell
10.0 out of 10, Exceptional, (2 reviews)
"The host is very friendly and accommodating. The unit is very nice, private and quite. The neighborhood is safe with resturants and shops within 15 minutes walk. Highly recommend this unit."
United States
Nasser K.
$274 nightly
The price is $314
Jun 21 - Jun 22
Total with taxes and fees
Delightful dwelling

2-bedroom House in beautiful Grand Island,NY! 4 miles from Niagara Falls!

2-bedroom House in beautiful Grand Island,NY! 4 miles from Niagara Falls!
Grand island
9.8 out of 10, Exceptional, (18 reviews)
"Accomodations were great"
United States
Ginny A.
$229 nightly
The price is $256
Jun 21 - Jun 22
Total with taxes and fees
2-bedroom House in beautiful Grand Island,NY! 4 miles from Niagara Falls!

Pet-Friendly Lancaster Home 13 Mi to Dtwn Buffalo

Pet-Friendly Lancaster Home 13 Mi to Dtwn Buffalo
Lancaster
10.0 out of 10, Exceptional, (31 reviews)
"It was great stay"
United States
Vomshankar R.
$401 nightly
The price is $445
Jul 6 - Jul 7
Total with taxes and fees
Pet-Friendly Lancaster Home 13 Mi to Dtwn Buffalo

Charming 2-bedroom apartment in Pleasant Blasdell with morning breakfast.

Charming 2-bedroom apartment in Pleasant Blasdell with morning breakfast.
Blasdell
9.8 out of 10, Exceptional, (8 reviews)
"The place was fairly clean. Well stocked and the hosts were incredibly nice! "
United States
Matthew
$258 nightly
The price is $288
Jun 21 - Jun 22
Total with taxes and fees
Charming 2-bedroom apartment in Pleasant Blasdell with morning breakfast.

Cozy 1-bedroom house in lovely Lockport with AC

Cozy 1-bedroom house in lovely Lockport with AC
Lockport
8.0 out of 10, Very Good, (1 review)
"Property was in nice neighborhood and good location in town. Staying here was better than at a hotel. Even though host bought new mattress, there was no box springs so bed was very low to floor, hard to get out of bed. Other than that stay was enjoyable."
United States
TERRI C.
$157 nightly
The price is $178
Jun 23 - Jun 24
Total with taxes and fees
Cozy 1-bedroom house in lovely Lockport with AC

4-Guest Suite in Beautiful Grand Island, NY! 4 miles from Niagara Falls!

4-Guest Suite in Beautiful Grand Island, NY! 4 miles from Niagara Falls!
Grand island
10.0 out of 10, Exceptional, (10 reviews)
"Nice welcoming amenities, is walking distance to a restaurant, and only a few minute drive to Casino and Niagara Falls. "
United States
Denise P.
$169 nightly
The price is $189
Jun 21 - Jun 22
Total with taxes and fees
4-Guest Suite in Beautiful Grand Island, NY! 4 miles from Niagara Falls!

Pet-friendly Lancaster Home 13 Mi to Dtwn Buffalo

Pet-friendly Lancaster Home 13 Mi to Dtwn Buffalo
3.0 star property
Lancaster
$397 nightly
The price is $444
Jul 6 - Jul 7
Total with taxes and fees
Pet-friendly Lancaster Home 13 Mi to Dtwn Buffalo

Suite Retreat: Cozy Walkable Akron Village Getaway

Suite Retreat: Cozy Walkable Akron Village Getaway
Akron
10.0 out of 10, Exceptional, (11 reviews)
"Easy check in process, very clean property with thoughtful touches and amenities that exceed expectations."
United States
Kellerie
$351 nightly
The price is $381
Jun 22 - Jun 23
Total with taxes and fees
Suite Retreat: Cozy Walkable Akron Village Getaway

11 min from BUF Airport, 19 min from Bills Stadium, 35 min from Niagara Falls!

11 min from BUF Airport, 19 min from Bills Stadium, 35 min from Niagara Falls!
Buffalo
10.0 out of 10, Exceptional, (10 reviews)
"Very clean and accomadating"
United States
Francis c.
$165 nightly
The price is $184
Jun 29 - Jun 30
Total with taxes and fees
11 min from BUF Airport, 19 min from Bills Stadium, 35 min from Niagara Falls!
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Depew Hotel Reviews

Find out more about Depew

Everything you need to know about Depew vacation rentals

Whether you’re excited for the perfect family vacation, a romantic getaway for two, or the ultimate city break, we’ve got the Depew vacation rental for you. At Expedia, you can take your pick from private vacation homes, apartments, condos, resorts, cabins, villas, motels. The list goes on, and on …and on.

There’s just as wide a choice of amenities, too. Maybe you’re dreaming of your own pool, long evenings in a hot tub, or watching the kids laugh through the day at a waterpark. Maybe you just want a quiet retreat in a pet-friendly apartment. Well, we can help you find it. Hunt out the perfect Depew vacation rental for you by simply entering your desired dates. Then check your favorite filters to narrow down your search.

Depew vacation rentals: An excellent choice for every season

Whenever you want to travel, a warm welcome awaits you in Depew. If you’re looking for a little peace, consider booking during the quieter low season months. For more hustle and bustle, you may prefer to visit Depew in high season.

Prices vary throughout the year. Your chosen location, property type, and amenities will impact the cost of your trip, too. The selection of properties we have chosen for you start as low as $100 per night. Rates vary depending on your travel dates, location, and amenities so make a search and you might find even better deals!

How to find incredible deals on Depew rentals

At Expedia, we put the best Depew vacation rentals in one place. All you need to do is take your pick. And as we offer book now, pay later options, as well as free cancellation on some properties, you can plan your trip with total peace of mind. You’ll always find a great deal with Expedia.

To find some top Depew rental deals, enter your travel dates, and sort your search results by price. You can also filter by budget, so you only see accommodation in your ballpark. Next, add any filters you want—and just like that, you’ve built your dream Depew vacation.

If you’re looking for a little inspiration, browse our latest incredible offers, or use the map to view all accommodation in and around Depew. And to unlock even more fantastic deals, bundle your accommodation, flights, and car rental together to save and book with Expedia in complete confidence.

Explore a world of travel with Expedia

Frequently asked questions

Can I find vacation rentals in Depew?

Yes, we have vacation rentals near well known sights in Depew, or you can choose a secluded option if you're looking for relaxation. Depew is known for its shopping and restaurants. Make sure you have time to check out the sporting events and waterfalls during your trip.

What are some of the best vacation home rentals in Depew?

HTR Niagara: Visitors like this Depew vacation home rental. It is on the riverwalk and equipped with air-conditioning and free WiFi to help you feel perfectly comfortable in your new surroundings. Amenities like a coffee maker and free parking are also available for your convenience.

How many vacation rentals will I find in Depew?

Choose from 6 Expedia vacation rentals in Depew for a memorable vacation.

What can I see and do in Depew?

While exploring the area, visit family-friendly sights like Six Flags Darien Lake, or get outside and enjoy nature at Glen Falls. Highmark Stadium and Holiday Twin Rinks are a couple of places you'll find in the larger area.

What are vacation rentals like in Depew?

Vacation rentals are private accommodations you can reserve for several days or more in Depew. Vacation rentals feature extras like WiFi and washers and dryers so you'll have everything you want. If you're concerned about a sanitized environment, a vacation rental can provide a sense of safety away from shared hotel elevators and busy lobbies while still allowing you a great travel experience. You'll also find more space in a vacation rental than in a standard hotel, which makes a vacation rental a great option for a family trip.