5/5 - Excellent
Verified traveler
My fiancé’s hometown area. We had a wonderful time.
Depew, NY
Travel Guide
Visit Depew
Buffalo Airport Hotel
4600 Genesee St Buffalo NY
Fully refundableReserve now, pay when you stay
$90 nightly
The price is $102 total per night from Feb 8 to Feb 9
$102 total
Feb 8 - Feb 9
Total with taxes and fees
Book a stay at this business-friendly hotel in Buffalo. Enjoy free WiFi, free parking, and a free airport shuttle. Our guests praise the restaurant and the helpful ...
7.8/10 Good! (2,878 reviews)
Very well located, spacious and clean rooms and very good price. Unfortunately, they do not have breakfast included.
Reviewed on Feb 2, 2026
Garden Place Hotel
6615 Transit Road Buffalo NY
$89 nightly
The price is $102 total per night from Feb 17 to Feb 18
$102 total
Feb 17 - Feb 18
Total with taxes and fees
Book a stay at this business-friendly hotel in Buffalo. Enjoy free parking, breakfast (surcharge), and a free airport shuttle. Our guests praise the helpful ...
7.6/10 Good! (2,251 reviews)
Always an enjoyable stay. Staff are very nice.
Reviewed on Feb 5, 2026
Hyatt Regency Buffalo / Hotel and Conference Center
Two Fountain Plaza Buffalo NY
$140 nightly
The price is $163 total per night from Feb 9 to Feb 10
$163 total
Feb 9 - Feb 10
Total with taxes and fees
Book a stay at this business-friendly hotel in Buffalo. Enjoy free WiFi, breakfast (surcharge), and a 24-hour fitness center. Our guests praise the helpful staff ...
8/10 Very Good! (1,739 reviews)
Need express check in option. Breakfast is way too expensive. If you're going to charge that much, at least have staff that serves me. Buffett is not acceptable at that price.
Reviewed on Feb 2, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Cozy 3-bedroom house in charming Buffalo with WiFi, AC
Buffalo NY
Stay at this apartment in Buffalo. Enjoy air conditioning. Popular attractions Walden Galleria Mall and KeyBank Center are located nearby.
8.4/10 Very Good! (15 reviews)
Small but definitely perfect for a quick trip! Communication with owner was great and accommodating! Would book again!
Reviewed on Nov 25, 2025
Right On the Niagara River - River Access Dock - Pool - Hot Tub - Firepit...more
Grand Island NY
Book a stay at this beach vacation home in Grand Island. Enjoy free WiFi, private pools, and a beach locale. Popular attractions Riviera Theatre and Performing ...
9.8/10 Exceptional! (126 reviews)
Definitely a family friendly location. We wish we could've stayed an extra day just to enjoy the house.
Reviewed on Oct 8, 2025
Tiny Spa Cottage Retreat
Alden NY
Stay at this cottage in Alden. Enjoy free WiFi, a water park, and laundry facilities. Popular attractions Six Flags Darien Lake and Darien Lakes State Park are ...
9.8/10 Exceptional! (115 reviews)
Loved it . So cute and had everything we needed. Host was very responsive. We will be back.
Reviewed on Jan 1, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Popular places to visit
University At Buffalo - North Campus
Enjoy the collegiate vibe when you visit University At Buffalo - North Campus, during your trip to Amherst. Experience the area's acclaimed theater scene and great live music.
KeyBank Center
Catch an event at KeyBank Center during your trip to Buffalo. Experience the area's great live music and acclaimed theater scene.
Highmark Stadium
Catch an event at Highmark Stadium during your trip to Orchard Park. Experience the area's entertainment choices and great live music.
Walden Galleria Mall
You can enjoy retail therapy at Walden Galleria Mall during your trip to Cheektowaga. Experience the area's entertainment choices and great live music.
Buffalo Zoo
See more than 1,200 animals at this small zoo in Buffalo’s Delaware Park. Explore the rainforest building or see the big cats of the African plains.
Canalside
Explore the great outdoors at Canalside, a lovely green space in Buffalo. Experience the entertainment choices and great live music in this family-friendly area.
Things to do
Theodore Roosevelt Inaugural National Historic Site Admission and Guided Tour
$13
per adult
100% of travellers recommend
Buffalo Sabres Ice Hockey Game at Keybank Center
$94
per adult
Niagara Falls Self-Guided Driving Audio Tour from Toronto
$17
per traveler
Niagara Falls USA: Full-Day Scenic Tour from Buffalo!
$151
per adult
Niagara Falls, USA: Guided Tour & Optional Maid of the Mist
$60
per adult
Niagara Falls USA: Night Illumination Tour & Optional Maid of the Mist
$54
per adult
Reviews of Depew
3.8
Guest rating
Explore a world of travel with Expedia
- Hotels near Reinstein Woods Nature Preserve and Environmental Education Center
- Hotels near Buffalo-Depew Station
- Hotels near Buffalo Niagara Intl.
- Hotels near Stiglmeier Park
- Hotels near Lancaster Opera House
- Hotels near Diamond Hawk Golf Course
- Hotels near Holiday Twin Rinks
- Cheektowaga Hotels
- Cheap Hotels in Cheektowaga
- Motels in Cheektowaga
- Hotels with an Indoor Pool in Cheektowaga
- Hotels with Restaurants in Cheektowaga
- Marriott Hotels & Resorts in Cheektowaga
- Pet-friendly Hotels in Cheektowaga
- Red Roof Inn Hotels in Cheektowaga
- B&B in Cheektowaga
- Extended Stay Hotels in Cheektowaga
- Luxury Hotels in Cheektowaga
- Hotel Wedding Venues Hotels in Cheektowaga
- Hotels with Kitchenettes in Cheektowaga
- Casino Hotels in Cheektowaga
- 4 Star Hotels in Cheektowaga
- Hotels with Hot Tubs in Cheektowaga
- Hotels with Connecting Rooms in Cheektowaga
- Historic Hotels in Cheektowaga
- Romantic Hotels in Cheektowaga
- Cabin Rentals in Cheektowaga
- La Quinta Inn & Suites Hotels in Cheektowaga
- Hotels with Free Breakfast in Cheektowaga
- Hotels with an Outdoor Pool in Cheektowaga
- Best Western Hotels in Cheektowaga
- Flights from New York (JFK) to Buffalo (BUF)
- Flights from Buffalo Niagara Intl.
- Flights from Atlanta (ATL) to Buffalo (BUF)
- Flights from Boston (BOS) to Buffalo (BUF)
- Flights from Orlando (MCO) to Buffalo (BUF)
- Flights from Dallas (DFW) to Buffalo (BUF)
- Flights from Los Angeles (LAX) to Buffalo (BUF)
- Flights from Tampa (TPA) to Buffalo (BUF)
- Flights from Chicago (ORD) to Buffalo (BUF)
- Flights from Charlotte (CLT) to Buffalo (BUF)
- Flights from Philadelphia (PHL) to Buffalo (BUF)
- Flights from Washington (DCA) to Buffalo (BUF)
- Flights from Raleigh (RDU) to Buffalo (BUF)
- Flights from Houston (HOU) to Buffalo (BUF)
- Flights from Fort Lauderdale (FLL) to Buffalo (BUF)
- Flights from Phoenix (PHX) to Buffalo (BUF)
- Flights from Denver (DEN) to Buffalo (BUF)
- Flights from New York (LGA) to Buffalo (BUF)
- Flights from San Francisco (SFO) to Buffalo (BUF)
- Flights from Minneapolis (MSP) to Buffalo (BUF)
- Flights from Baltimore (BWI) to Buffalo (BUF)
- Flights from Pittsburgh (PIT) to Buffalo (BUF)
- Flights from Miami (MIA) to Buffalo (BUF)
- Flights from Las Vegas (LAS) to Buffalo (BUF)
- Flights from Detroit (DTW) to Buffalo (BUF)
- Flights from Seattle (SEA) to Buffalo (BUF)
- Flights from Albany (ALB) to Buffalo (BUF)
- Flights from New York (NYC) to Buffalo (BUF)
- Flights from Hartford (BDL) to Buffalo (BUF)
- Flights from Austin (AUS) to Buffalo (BUF)
- Flights from Jacksonville (JAX) to Buffalo (BUF)
- Flights from Toronto (YYZ) to Buffalo (BUF)
- Flights from Fort Myers (RSW) to Buffalo (BUF)
- Flights from San Diego (SAN) to Buffalo (BUF)
- Flights from Nashville (BNA) to Buffalo (BUF)
- Flights from Rochester (ROC) to Buffalo (BUF)
- Flights from Cleveland (CLE) to Buffalo (BUF)
- Flights from Salt Lake City (SLC) to Buffalo (BUF)
- Flights from Kansas City (MCI) to Buffalo (BUF)
- Flights from Columbus (CMH) to Buffalo (BUF)
- Flights from Syracuse (SYR) to Buffalo (BUF)
- Flights from Cincinnati (CVG) to Buffalo (BUF)
- Flights from Indianapolis (IND) to Buffalo (BUF)
- Flights from White Plains (HPN) to Buffalo (BUF)
- Flights from Richmond (RIC) to Buffalo (BUF)
- Flights to Cheektowaga
- Flights from West Palm Beach (PBI) to Buffalo (BUF)
- Flights from Islip (ISP) to Buffalo (BUF)
- Flights from Washington (IAD) to Buffalo (BUF)
- Flights from St. Louis (STL) to Buffalo (BUF)
- Flights from Cheektowaga
- Car rental Buffalo Airport (BUF)
- Car rentals near Bellevue
- Car rentals near Cheektowaga
- Budget Rental Cars in Buffalo Niagara Intl.
- Hertz Rental Cars in Buffalo Niagara Intl.
- Enterprise Rental Cars in Cheektowaga
- Hertz Rental Cars in Cheektowaga
- Budget Rental Cars in Cheektowaga
- Advantage Rent-A-Car Rental Cars in Cheektowaga
- University At Buffalo - North Campus
- KeyBank Center
- Highmark Stadium
- Six Flags Darien Lake
- Walden Galleria Mall
- Fashion Outlets of Niagara Falls
- Buffalo Niagara Convention Center
- Buffalo Zoo
- Shea's Performing Arts Center
- University at Buffalo - South Campus
- Canalside
- Buffalo State College
- Sahlen Field
- Hamburg Fairgrounds
- Niagara Square
- Roswell Park Cancer Institute
- Darien Lake Performing Arts Center
- Canisius College
- Buffalo AKG Art Museum
- Peace Bridge
- Buffalo and Erie County Naval and Military Park
- Eternal Flame Falls
- University at Buffalo - Downtown Campus
- Burt Flickinger Athletic Center
- Buffalo Museum of Science
- Kleinhans Music Hall
- Buffalo City Hall
- Millard Fillmore Suburban Hospital
- Buffalo and Erie County Botanical Gardens
