Distrito Colón Vacations & Trips from $774
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Your Distrito Colón Vacation
Set off on your next thrilling adventure with a Distrito Colón vacation package, and leave relaxed knowing the finer details are organized. And with the ability to tailor your escape, you know it'll be one to remember. A trip to Distrito Colón wouldn't be complete without spending a day or two in Colon. This city is among the top places to visit here. Expedia is a one-stop shop for organizing your Distrito Colón vacation. From hotels and flights, to activities and more, we know how to curate a travel experience like no other.
The Latest Distrito Colón Vacation Packages
Price found within the past 48 hours. Click for updated prices.
Yoo by Wynwood House
Calidonia
$774
per person
Oct 19 - Oct 23
found 1 day ago
Roundtrip flight included
Miami (MIA) to Panama City (PTY)
9.4/10 Exceptional! (6 reviews)
Unfortunately the name of the property was not Yoo by Wynwood. It is P. H. Yoo Panama & Arts Tower. This detail that was incorrect cost us time, money and stress at the beginning of our trip. We weren't able to get in touch with anyone at the property or at expedia and we ended up having to cross reference google photos to figure out the correct name and address of the location. This took us about an hour to do in a Country that we had never been to. We are very displeased with Expedia about this. We still have not been contacted by anyone.
Reviewed on Jul 26, 2025
Central Hotel Panama Casco Viejo
Casco Viejo
$1,095
per person
Nov 5 - Nov 10
found 1 day ago
Roundtrip flight included
Newark Liberty Intl. Airport (EWR) to Panama City (PTY)
9.2/10 Wonderful! (1,001 reviews)
Beautiful historic hotel we stayed there for 5 nights with a group of 33 people celebrating my brother’s 50 th birthday. very central, you can walk to go shopping or eating and dining at the roof top restaurants in the hotel or around Casco.
The cocktails at the bar delicious and the breakfast was great variety, food was fresh. I’d rate the hotel Uber from there quick and cheap…….,10/10 great experience. The staff was also nice and very accommodating.
Reviewed on Sep 2, 2026
Find the Best Distrito Colón Vacation Packages
Distrito Colón Essential Information
Language | Spanish |
|---|---|
Currency | Panamanian balboas |
Local Welcome | ¡Hola! |
Local Goodbye | Adiós |
Distrito Colón Hotel Deals
Gamboa Rainforest Reserve
Corregimiento de Cristobal, IA 5 Colon Colon
Fully refundableReserve now, pay when you stay
$137 nightly
$151 total
Sep 28 - Sep 29
Total with taxes and fees
8/10 Very Good! (804 reviews)
"We recently stayed at the Gamboa Rainforest Reserve, and the hotel is ideally located right in the heart of the rainforest. There are plenty of activities available, and you can easily sign up for tours and excursions during your stay. The staff were excellent. We had originally booked three nights ..."
Reviewed on Sep 3, 2026
Hotel Riu Plaza Panama
Calle 50, Urb. Marbella Panama City Panama
Fully refundableReserve now, pay when you stay
$123 nightly
$135 total
Sep 28 - Sep 29
Total with taxes and fees
9/10 Wonderful! (5,910 reviews)
"The hotel was constantly crowded"
Reviewed on Sep 3, 2026
Central Hotel Panama Casco Viejo
Plaza de la Independencia Casco Viejo Panama City Panama
Fully refundableReserve now, pay when you stay
$183 nightly
$202 total
Oct 3 - Oct 4
Total with taxes and fees
9/10 Wonderful! (1,004 reviews)
"Beautiful historic hotel we stayed there for 5 nights with a group of 33 people celebrating my brother’s 50 th birthday. very central, you can walk to go shopping or eating and dining at the roof top restaurants in the hotel or around Casco. The cocktails at the bar delicious and the breakfast was ..."
Reviewed on Sep 2, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Stay near popular Distrito Colón attractions
Fort San Lorenzo
8.4/10 (36 reviews)
You can learn about the history of Colon with a stop at Fort San Lorenzo. Stroll along this relaxing area's lakeside, or simply enjoy its restaurants.
Colon 2000
7.6/10 (88 reviews)
During your visit to Colon, you can search for that perfect souvenir at Colon 2000. Stroll along this relaxing area's lakeside, or simply enjoy its restaurants.
Colon Free Zone
7.8/10 (127 reviews)
During your trip to Colon, you can search for that perfect souvenir at Colon Free Zone.
Gamboa Rainforest Resort
8.4/10 (571 reviews)
Explore the great outdoors at Gamboa Rainforest Resort, a lovely green space in Gamboa. While you're here, you can savor the top-notch restaurants.
Gatun Locks
8.6/10 (61 reviews)
After visiting Gatun Locks, make a plan to see the other sights and activities in Colon. Stroll along this relaxing area's lakeside, or simply enjoy its restaurants.
Galeta Island Marine Education Center
8.2/10 (21 reviews)
You can spend an afternoon browsing the exhibits at Galeta Island Marine Education Center during your trip to Colon. Stroll along this relaxing area's lakeside, or simply enjoy its restaurants.
Canal Expansion Observation Center
9.2/10 (34 reviews)
You can spend time exploring the galleries in Canal Expansion Observation Center during your trip to Colon. Stroll along this relaxing area's lakeside, or simply enjoy its restaurants.
Monument to Christopher Columbus
8.2/10 (21 reviews)
You can learn about the history of Colon with a stop at Monument to Christopher Columbus. Stroll along this relaxing area's lakeside, or simply enjoy its restaurants.
What to do in Distrito Colón
Monkey and Sloth Jungle Habitat Panama Tour
$42
per adult
96% of travellers recommend
Monkey Watch and Gatun Lake Wildlife Safari Private Tour
$75
per adult
Explore Panama Canal and Gatun Lake with Rainforest Jungle Walk
$109
per adult
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