Title: Doe Run Vacation Packages 2026 from $869 | Expedia.com [Doe Run Travel Guide](https://expedia.com/Doe-Run.dx3000349343)[Hotels in Doe Run](https://expedia.com/Doe-Run-Hotels.d3000349343.Travel-Guide-Hotels)[Vacation Rentals in Doe Run](https://expedia.com/Doe-Run-Vacation-Rentals.d3000349343.Travel-Guide-VacationRentals)[Flights to Doe Run](https://expedia.com/Cheap-Flights-To-Doe-Run.d3000349343.Travel-Guide-Flights)[Car Rentals in Doe Run](https://expedia.com/Car-Rentals-In-Doe-Run.d3000349343.Car-Rental-Guide) ![](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_packages.jpeg?impolicy=fcrop&w=1200&h=300&q=medium) # Doe Run Vacations from $869 ## Book a Hotel + Flight or Car together to unlock savings - ## Plan, book, travel with confidence - ### Better together Save up to $1,045 when you book a flight and hotel together\* - ### Find the right fit With over 300,000 hotels worldwide, it's easy to create a perfect package - ### Rest easy Plan, book, and manage your trip all in one place ## Your Doe Run Vacation Take the stress out of organizing your next big adventure with a Doe Run vacation package. Whether you're visiting for its history, food or something else, this city offers limitless opportunities for discovery. Looking for some sightseeing inspiration for your trip to Doe Run? [St. Joe State Park](https://www.expedia.com/St-Joe-State-Park-Missouri.d553248621532648468.Vacation-Attraction) and [Crown Pointe Golf Club](https://www.expedia.com/Crown-Pointe-Golf-Club-Farmington.d553248623407989977.Vacation-Attraction) are two leading attractions here. Browse Expedia's wide range of travel options and start organizing your dream vacation to Doe Run today. ## The Latest Doe Run vacation packages Price found within the past 48 hours. Click for updated prices. ![EC Reed's Mercantile and Hotel](https://images.trvl-media.com/lodging/75000000/74670000/74660800/74660768/fc288d3b_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### EC Reed's Mercantile and Hotel $869 per person Apr 10 - Apr 12 found 12 hours ago Roundtrip flight included Fresno (FAT) to Cape Girardeau (CGI) 9.6/10 Exceptional! (82 reviews) Clean rooms, great value. Reviewed on Nov 28, 2025 ![Drury Plaza Hotel Cape Girardeau Conference Center](https://images.trvl-media.com/lodging/18000000/17270000/17270000/17269948/742aaf1e_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Drury Plaza Hotel Cape Girardeau Conference Center $923 per person Apr 10 - Apr 12 found 12 hours ago Roundtrip flight included Fresno (FAT) to Cape Girardeau (CGI) 9.6/10 Exceptional! (1,003 reviews) Lovely room..bed so bet comfy..but we had very loud toilet ! Reviewed on Feb 28, 2026 ![Drury Inn & Suites Cape Girardeau](https://images.trvl-media.com/lodging/1000000/50000/40900/40831/4b521966_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Drury Inn & Suites Cape Girardeau $921 per person Apr 10 - Apr 12 found 12 hours ago Roundtrip flight included Fresno (FAT) to Cape Girardeau (CGI) 9.4/10 Exceptional! (1,000 reviews) Everything above was excellent Reviewed on Feb 27, 2026 ![Drury Inn & Suites Jackson MO](https://images.trvl-media.com/lodging/1000000/50000/41100/41077/8996a36d_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Drury Inn & Suites Jackson MO $912 per person Apr 10 - Apr 12 found 12 hours ago Roundtrip flight included Fresno (FAT) to Cape Girardeau (CGI) 9.6/10 Exceptional! (1,003 reviews) The best all around hotel experience I’ve had Reviewed on Feb 27, 2026 ![The Riverview](https://images.trvl-media.com/lodging/106000000/105090000/105081400/105081384/d68c9046_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### The Riverview $934 per person Apr 10 - Apr 12 found 12 hours ago Roundtrip flight included Fresno (FAT) to Cape Girardeau (CGI) 9.4/10 Exceptional! (452 reviews) The room was perfect for the evening and occasion! Reviewed on Feb 21, 2026 Don't see what you're looking for? See all available trips from Boydton to Doe Run [View all trips](https://expedia.com/go/package/search/FlightHotel/2026-04-01/2026-04-08/?FromAirport=Boydton,%20Virginia,%20United%20States%20of%20America&Destination=null&NumRoom=1&NumAdult=2&NumChild=0&paandie=true) ![](https://forever.travel-assets.com/flex/flexmanager/images/2026/02/06/expedia-sale-2026-desktop-us-ca.jpg?impolicy=fcrop&w=1400&h=600&q=mediumHigh) ## The Annual Vacation Sale Members save up to 40% on hotels and homes. Plan this year’s big trip and save. [Book now](https://expedia.com/deals?rfrr=PKG_SPRING_PROMO_3000349343) ## Doe Run Hotel Deals ![16 Acres of beauty and relaxation ](https://images.trvl-media.com/lodging/93000000/92190000/92187000/92186937/6207afd7_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### 16 Acres of beauty and relaxation Park Hills MO 9.8/10 Exceptional! (20 reviews) Quiet peaceful and secluded. Exactly what the doctor ordered ! Reviewed on Feb 2, 2026 [Get rates](https://expedia.com/Hotel-Search?startDate=3%2F15%2F2026&endDate=3%2F16%2F2026&selected=92186937&PinnedHotelID=92186937&HadPinnedHotel=true®ionId=3000349343) [](https://expedia.com/Hotel-Search?startDate=3%2F15%2F2026&endDate=3%2F16%2F2026&selected=92186937&PinnedHotelID=92186937&HadPinnedHotel=true®ionId=3000349343) ![Baymont Inn and Suites by Wyndham Farmington, MO](https://images.trvl-media.com/lodging/1000000/20000/16200/16153/02759b26_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Baymont Inn and Suites by Wyndham Farmington, MO 1625 W Columbia St Farmington MO Fully refundableReserve now, pay when you stay $58 nightly $66 total Mar 8 - Mar 9 Total with taxes and fees 8/10 Very Good! (1,004 reviews) Clean room and hotel. Comfy bed as well. Great stay. Reviewed on Feb 28, 2026 [](https://expedia.com/Hotel-Search?startDate=3%2F8%2F2026&endDate=3%2F9%2F2026&selected=16153&PinnedHotelID=16153&HadPinnedHotel=true®ionId=3000349343) ### Postcard Cabins St Francois, Outdoor Collection by Marriott Bonvoy 7555 State Hwy Y French Village MO $109 nightly $117 total Mar 2 - Mar 3 Total with taxes and fees 9.8/10 Exceptional! (54 reviews) Everything stood out from the staff to the view. Our time there was the most peaceful and perfect. The staff was incredibly helpful with bring extra amenities and even brought us a cast iron skillet. The staff here goes the extra mile in every aspect. One of the best places I’ve ever had the pleasure ... Reviewed on Feb 24, 2026 [](https://expedia.com/Hotel-Search?startDate=3%2F2%2F2026&endDate=3%2F3%2F2026&selected=110550817&PinnedHotelID=110550817&HadPinnedHotel=true®ionId=3000349343) [See all 142 properties in Doe Run](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.Package&startDate=3%2F2%2F2026&endDate=3%2F3%2F2026®ionId=3000349343) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. ## Find the Best Doe Run Vacation Packages ## Doe Run Essential Information | Language | English | | ---------- | -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- | | Currency | U.S dollars | | Population | 920 | | Top Sights | [Twin Oaks Vineyard & Winery](https://www.expedia.com/Twin-Oaks-Vineyard-Winery-Farmington.d553248621532648471.Vacation-Attraction), [Sand Creek Winery](https://www.expedia.com/Sand-Creek-Winery-Farmington.d553248621532648472.Vacation-Attraction) and [Crown Pointe Golf Club](https://www.expedia.com/Crown-Pointe-Golf-Club-Farmington.d553248623407989977.Vacation-Attraction) | ## More vacations you might like 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