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Find hotels in Eastern South Dakota, SD from $63

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Compare 829 hotels, room rates, hotel reviews and availability. Most hotels are fully refundable.

Our top choices for Eastern South Dakota hotels

AeroStay Hotel
Front of property

AeroStay Hotel

2.5 star property
8.8 out of 10, Excellent, (1004)
"Perfect hotel for a few overnights. "
$132 nightly
The price is $147
Sep 2 - Sep 3
Total with taxes and fees
AeroStay Hotel
AmericInn by Wyndham Hartford SD
Exterior

AmericInn by Wyndham Hartford SD

2.5 star property
9.2 out of 10, Wonderful, (744)
"Very nice hotel, good breakfast, clean, and friendly staff!"
$88 nightly
The price is $95
Sep 14 - Sep 15
Total with taxes and fees
AmericInn by Wyndham Hartford SD
Comfort Inn & Suites at Sanford Sports Complex
Exterior

Comfort Inn & Suites at Sanford Sports Complex

2.5 star property
9.6 out of 10, Exceptional, (698)
"Great stay"
$103 nightly
The price is $115
Sep 14 - Sep 15
Total with taxes and fees
Comfort Inn & Suites at Sanford Sports Complex
Clarion Pointe Sioux Falls Airport
Lobby lounge

Clarion Pointe Sioux Falls Airport

2.5 star property
8.8 out of 10, Excellent, (1029)
"Staff was amazing!!"
$99 nightly
The price is $110
Sep 14 - Sep 15
Total with taxes and fees
Clarion Pointe Sioux Falls Airport
Grandstay Hotel And Suites Luverne
Indoor pool

Grandstay Hotel And Suites Luverne

2.5 star property
9.2 out of 10, Wonderful, (710)
"Great town enjoyed our stay! Great pool area!"
$109 nightly
The price is $120
Sep 7 - Sep 8
Total with taxes and fees
Grandstay Hotel And Suites Luverne
Best Western Vermillion Inn
Suite, 1 King Bed, Non Smoking, Refrigerator & Microwave (Walk-in Shower;with Sofabed) | 1 bedroom, in-room safe, laptop workspace, iron/ironing board

Best Western Vermillion Inn

2.5 star property
8.8 out of 10, Excellent, (534)
"Best place I’ve stayed in Vermillion. "
$96 nightly
The price is $106
Sep 14 - Sep 15
Total with taxes and fees
Best Western Vermillion Inn
Royal River Casino and Hotel
Lobby sitting area

Royal River Casino and Hotel

3.0 star property
8.6 out of 10, Excellent, (521)
"Always a good place to stay"
$105 nightly
The price is $120
Sep 1 - Sep 2
Total with taxes and fees
Royal River Casino and Hotel
Days Inn by Wyndham Sioux Falls Airport
Desk, blackout drapes, soundproofing, iron/ironing board

Days Inn by Wyndham Sioux Falls Airport

2.0 star property
7.2 out of 10, Good, (1028)
"Hotel was clean and quiet."
$60 nightly
The price is $67
Sep 21 - Sep 22
Total with taxes and fees
Days Inn by Wyndham Sioux Falls Airport
Super 8 by Wyndham Brookings
Exterior

Super 8 by Wyndham Brookings

2.0 star property
8.8 out of 10, Excellent, (1006)
"Great place for a quick stop over. "
$76 nightly
The price is $84
Sep 7 - Sep 8
Total with taxes and fees
Super 8 by Wyndham Brookings
Gateway Park Hotel and Suites
Indoor pool

Gateway Park Hotel and Suites

2.5 star property
9.2 out of 10, Wonderful, (1006)
"Check in was fast, the staff was very friendly and the place was very clean."
$109 nightly
The price is $118
Sep 1 - Sep 2
Total with taxes and fees
Gateway Park Hotel and Suites
Country Inn & Suites by Radisson, Brookings, SD
Premium bedding, desk, laptop workspace, blackout drapes

Country Inn & Suites by Radisson, Brookings, SD

2.5 star property
8.4 out of 10, Very Good, (781)
"Property was clean and staff was friendly "
$93 nightly
The price is $103
Sep 21 - Sep 22
Total with taxes and fees
Country Inn & Suites by Radisson, Brookings, SD
Crossroads Hotel at Huron Event Center
Reception

Crossroads Hotel at Huron Event Center

2.5 star property
7.8 out of 10, Good, (543)
"Comfortable beds, quiet, clean, friendly staff, restaurant in hotel, has elevator to floors, breakfast provided, has ample parking, conveniently located to downtown within walking distance"
$91 nightly
The price is $101
Sep 14 - Sep 15
Total with taxes and fees
Crossroads Hotel at Huron Event Center
Thunderbird Lodge
Front of property

Thunderbird Lodge

2.0 star property
8.4 out of 10, Very Good, (1217)
"Excellent staff and room was nice and clean."
$70 nightly
The price is $78
Sep 10 - Sep 11
Total with taxes and fees
Thunderbird Lodge
Comfort Inn & Suites Mitchell I-90
Lobby

Comfort Inn & Suites Mitchell I-90

2.5 star property
8.8 out of 10, Excellent, (944)
"Dining nearby, kids loved the pool "
$109 nightly
The price is $122
Sep 28 - Sep 29
Total with taxes and fees
Comfort Inn & Suites Mitchell I-90
My Place Hotel-Mitchell, SD
Front of property

My Place Hotel-Mitchell, SD

2.0 star property
9.4 out of 10, Exceptional, (356)
"A good place to stay!"
$105 nightly
The price is $116
Sep 28 - Sep 29
Total with taxes and fees
My Place Hotel-Mitchell, SD
Quality Inn Brookings - University
Flat-screen TV

Quality Inn Brookings - University

2.5 star property
8.0 out of 10, Very Good, (599)
"Great stay for what we needed in the area."
$65 nightly
The price is $72
Sep 14 - Sep 15
Total with taxes and fees
Quality Inn Brookings - University
My Place Hotel - Watertown, SD
Front of property

My Place Hotel - Watertown, SD

2.5 star property
9.4 out of 10, Exceptional, (906)
"Super clean and a great staff."
$92 nightly
The price is $103
Sep 1 - Sep 2
Total with taxes and fees
My Place Hotel - Watertown, SD
AmericInn by Wyndham Sioux Falls North
Exterior

AmericInn by Wyndham Sioux Falls North

2.5 star property
9.0 out of 10, Wonderful, (1418)
"Nice clean hotel."
$105 nightly
The price is $118
Sep 1 - Sep 2
Total with taxes and fees
AmericInn by Wyndham Sioux Falls North
Comfort Suites University
1 bedroom, premium bedding, individually decorated

Comfort Suites University

2.5 star property
9.4 out of 10, Exceptional, (708)
"Very nice rooms, beds were comfortable, and room was very clean! "
$107 nightly
The price is $118
Sep 28 - Sep 29
Total with taxes and fees
Comfort Suites University
GLō Best Western Dawley Farms In Sioux Falls
1 bedroom, premium bedding, pillowtop beds, laptop workspace

GLō Best Western Dawley Farms In Sioux Falls

3.0 star property
8.8 out of 10, Excellent, (728)
"Good place to stay."
$96 nightly
The price is $107
Sep 2 - Sep 3
Total with taxes and fees
GLō Best Western Dawley Farms In Sioux Falls
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Great weekend hotel deals in Eastern South Dakota, SD

Showing deals for:Sep 12 - Sep 14

Image gallery for Americas Best Value Inn & Suites Clear Lake

Lobby

Americas Best Value Inn & Suites Clear Lake

2.0 star property
Clear Lake
8.0/10Very Good (183 reviews)
20% off
$70 nightly
Price is $153
Total with taxes and fees
Americas Best Value Inn & Suites Clear Lake
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Check out pet-friendly hotels in Eastern South Dakota

AeroStay Hotel
Front of property

AeroStay Hotel

2.5 star property
8.8 out of 10, Excellent, (1004)
$132 nightly
The price is $147
Sep 2 - Sep 3
Total with taxes and fees
AeroStay Hotel

Hotels with a spa in Eastern South Dakota you'll enjoy

Hampton Inn & Suites Brookings
Exterior

Hampton Inn & Suites Brookings

2.5 star property
9.2 out of 10, Wonderful, (589)
$118 nightly
The price is $130
Sep 7 - Sep 8
Total with taxes and fees
Hampton Inn & Suites Brookings

These family-friendly hotels in Eastern South Dakota may fit your trip

Clarion Pointe Sioux Falls Airport
Lobby lounge

Clarion Pointe Sioux Falls Airport

2.5 star property
8.8 out of 10, Excellent, (1029)
$99 nightly
The price is $110
Sep 14 - Sep 15
Total with taxes and fees
Clarion Pointe Sioux Falls Airport
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Stay near popular Eastern South Dakota attractions

Falls Park
Sioux Falls featuring a park and a waterfall

Falls Park

Falls Park is just one of the places to see in Sioux Falls, so why not enjoy the other things to explore during your travels? Attend a sporting event or discover the area's beautiful waterfalls.

See properties in Falls Park
Corn Palace
Corn Palace

Corn Palace

After visiting Corn Palace, make a plan to see the other sights and activities in Mitchell. While in this family-friendly area, you can savor the top-notch restaurants.

See properties in Corn Palace

Learn more about Eastern South Dakota

Experience the family-friendly area of Eastern South Dakota—waterfalls, restaurants, and sights from Ingalls Homestead to Lake Thompson Recreation Area.

See all hotels in Eastern South Dakota
De Smet showing heritage elements and an administrative buidling
Photo by De Smet Development Corporation
Open Photo by De Smet Development Corporation

Top Eastern South Dakota Hotel Reviews

More cheap stays in Eastern South Dakota

More cheap stays in Eastern South Dakota

Days Inn by Wyndham Sioux Falls Empire

Days Inn by Wyndham Sioux Falls Empire

3401 Gateway Blvd, I-29 and 41st Street Exit 77, Sioux Falls, SD
$60 nightly
The price is $68 total per night from Sep 2 to Sep 3
$68 total
Sep 2 - Sep 3
Total with taxes and fees

Hotels in Eastern South Dakota with star-rating

Hotels in Eastern South Dakota with star-rating

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Explore a world of travel with Expedia