Photo by Southernmost Illinois Tourism Bureau
Search Vacation Homes in Southern Illinois
- Bundle & SaveGet more, spend less whenever you see Bundle & Save deals
- OneKeyCashEarn OneKeyCash on all your eligible bookings
- Upfront pricingWe are not like the others - we include taxes and fees
Check prices for these dates
Next weekend
In two weeks
In one month
In two months
Vacation Homes in Southern Illinois

Vacation Home in Simpson
10.0 out of 10, Exceptional, (26)
$203 nightly
The price is $215
Dec 9 - Dec 10
Total with taxes and fees

Vacation Home in Greenup
10.0 out of 10, Exceptional, (59)
$131 nightly
The price is $138
Dec 9 - Dec 10
Total with taxes and fees

Vacation Home in Harrisburg
9.8 out of 10, Exceptional, (22)
$160 nightly
The price is $170
Dec 9 - Dec 10
Total with taxes and fees

Vacation Home in Eddyville
10.0 out of 10, Exceptional, (15)
$145 nightly
The price is $154
Dec 9 - Dec 10
Total with taxes and fees

Vacation Home in Mattoon
9.8 out of 10, Exceptional, (39)
$171 nightly
The price is $181
Dec 9 - Dec 10
Total with taxes and fees

Vacation Home in Creal Springs
10.0 out of 10, Exceptional, (2)
$397 nightly
The price is $440
Dec 9 - Dec 10
Total with taxes and fees

Vacation Home in Pomona
10.0 out of 10, Exceptional, (60)
$159 nightly
The price is $169
Dec 9 - Dec 10
Total with taxes and fees

Vacation Home in Vienna
10.0 out of 10, Exceptional, (2)
$158 nightly
The price is $168
Dec 9 - Dec 10
Total with taxes and fees
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Top Southern Illinois Hotel Reviews

Holiday Inn Express Metropolis by IHG
10/10 Excellent
Find out more about Southern Illinois
Southern Illinois Vacation Homes information
Number of reviews | 702 |
|---|---|
Accommodation | 386 Vacation Homes |
Lowest Price | $138 |
Highest Price | $440 |
Explore a world of travel with Expedia
- Mount Vernon Hotels
- Hotels near Jefferson County Fairgrounds
- Hotels near Mount Vernon Outland
- Cabin Rentals in Mount Vernon
- Motels in Mount Vernon
- Apartments in Mount Vernon
- RV Parks in Mount Vernon
- Vacation Homes in Opdyke
- Pet-friendly Hotels in Mount Vernon
- Cheap Hotels in Mount Vernon
- Hotels with Bars in Mount Vernon
- Hotels with Restaurants in Mount Vernon
- Hotels with Hot Tubs in Mount Vernon
- 5 Star Hotels in Mount Vernon
- Hotels with an Indoor Pool in Mount Vernon
- Hotels with an Outdoor Pool in Mount Vernon
- Luxury Hotels in Mount Vernon
- Hotels with Free Breakfast in Mount Vernon
- 4 Star Hotels in Mount Vernon
- Resorts & Hotels with Spas in Mount Vernon
- Best Western Hotels in Mount Vernon
- Hotels with Connecting Rooms in Mount Vernon
- Non-Smoking Hotels in Mount Vernon
- Hotel Wedding Venues Hotels in Mount Vernon
- Hotels with Room Service in Mount Vernon
- Marriott Hotels & Resorts in Mount Vernon
- Hotels with Laundry Facilities in Mount Vernon
- Hotels with Free Parking in Mount Vernon
- Family Hotels in Mount Vernon
- Hotels with Balconies in Mount Vernon
- Hotels & Resorts for Couples in Mount Vernon
- Golf Hotels in Mount Vernon
- Hotels with a Gym in Mount Vernon
- Hotels with Suites in Mount Vernon
- Hotels with Air Conditioning in Mount Vernon
- Gay friendly Hotels in Mount Vernon
- Hotels with a Pool in Mount Vernon
- 3 Star Hotels in Mount Vernon
- Wyndham Hotels in Mount Vernon
- Business Hotels in Mount Vernon
- Opdyke Hotels
- 5 Star Hotels in Opdyke
- 4 Star Hotels in Opdyke
- Hotels near Veterans Memorial Park
- Hotels near King City Square Shopping Center
- Bonnie Hotels
- Cabin Rentals in Belle Rive
- Flights from Mount Vernon Outland
- Flights from Chicago (ORD) to Mount Vernon (MVN)
- Flights from Nashville (BNA) to Mount Vernon (MVN)
- Flights from Houston (HOU) to Mount Vernon (MVN)
- Flights from Denver (DEN) to Mount Vernon (MVN)
- Flights from Orlando (MCO) to Mount Vernon (MVN)
- Flights from Detroit (DTW) to Mount Vernon (MVN)
- Flights from Charlotte (CLT) to Mount Vernon (MVN)
- Flights from San Diego (SAN) to Mount Vernon (MVN)
- Flights from Baltimore (BWI) to Mount Vernon (MVN)
- Flights from Seattle (SEA) to Mount Vernon (MVN)
- Flights from Minneapolis (MSP) to Mount Vernon (MVN)
- Flights from Raleigh (RDU) to Mount Vernon (MVN)
- Flights from Pensacola (PNS) to Mount Vernon (MVN)
- Flights from Vancouver (YVR) to Mount Vernon (MVN)
- Flights from Atlanta (ATL) to Mount Vernon (MVN)
- Flights from Fort Myers (RSW) to Mount Vernon (MVN)
- Flights from Buffalo (BUF) to Mount Vernon (MVN)
- Flights from Grand Rapids (GRR) to Mount Vernon (MVN)
- Flights from Manchester (MAN) to Mount Vernon (MVN)
- Flights from Los Angeles (LAX) to Mount Vernon (MVN)
- Flights from Tampa (TPA) to Mount Vernon (MVN)
- Flights from Charlottesville (CHO) to Mount Vernon (MVN)
- Hopscotch Air Chicago (MDW) to Mount Vernon (MVN) flights
- Flights from Cape Girardeau (CGI) to Mount Vernon (MVN)
- Flights to Mount Vernon
- Flights from Mount Vernon
- Flights from Nashville to Mount Vernon
- Flights from Los Angeles to Mount Vernon
- Flights from Hilo to Mount Vernon
- Flights from Charlottesville to Mount Vernon
- Flights from Atlanta to Mount Vernon
- Flights from Buffalo to Mount Vernon
- Flights from Palm Beach to Mount Vernon
- Flights from West Palm Beach to Mount Vernon
- Flights from Amsterdam to Mount Vernon
- Flights from Opdyke
- Car rental Mount Vernon Airport (MVN)
- Car rentals near Mount Vernon
- Hertz Rental Cars in Mount Vernon
- Avis Rental Cars in Mount Vernon
- Enterprise Rental Cars in Mount Vernon
- Budget Rental Cars in Mount Vernon
- National Car Rental Rental Cars in Mount Vernon
- Alamo Rent A Car Rental Cars in Mount Vernon
- Car rentals near Opdyke
















































































