Isla Canas Vacations from $706

Book a Hotel + Flight or Car together to unlock savings

Plan, book, travel with confidence
Better together
Save up to $2,000 when you book a flight and hotel together*
Find the right fit
With over 300,000 hotels worldwide, it's easy to create a perfect package
Rest easy
Plan, book, and manage your trip all in one place

The Latest Isla Canas vacation packages

Price found within the past 48 hours. Click for updated prices.

Plaza Paitilla Inn Hotel

San Francisco

$706

per person

Dec 21 - Dec 24

found 1 day ago

Roundtrip flight included

Kingston (KIN) to Panama City (PTY)

9.4/10 Exceptional! (2,246 reviews)

Central Hotel Panama Casco Viejo

Casco Viejo

Save 100% on your flight

$1,407

per person

Nov 23 - Nov 29

found 1 day ago

Roundtrip flight included

Newark Liberty Intl. Airport (EWR) to Panama City (PTY)

9/10 Wonderful! (1,006 reviews)

Property was clean and nice, breakfast was excellent.

Reviewed on Oct 20, 2026

Megapolis Hotel Panamá

San Francisco

Save 100% on your flight

$1,286

per person

Nov 26 - Dec 3

found 1 day ago

Roundtrip flight included

Newark Liberty Intl. Airport (EWR) to Panama City (PTY)

8.6/10 Excellent! (1,764 reviews)

Riande Aeropuerto Hotel & Casino

Tocumen Airport

$1,037

per person

Nov 23 - Nov 29

found 1 day ago

Roundtrip flight included

Newark Liberty Intl. Airport (EWR) to Panama City (PTY)

8.6/10 Excellent! (1,819 reviews)

Casa Mallet by Wynwood House

Casco Viejo

Save 100% on your flight

$2,929

per person

Dec 27 - Jan 1

found 1 day ago

Roundtrip flight included

Kingston (KIN) to Panama City (PTY)

9.8/10 Exceptional! (30 reviews)

I would highly recommend, the service I received was impeccable and just a wonderful experience! I was a bit hesitant regarding the location but once I got there, it turned out to be perfect. The concierge staff was such a pleasure to work with especially ‘Jerry’, who provided recommendations and information. This was such a blessing to us. I would stay here again in a heart beat. It’s a must stay!

Reviewed on Sep 16, 2026

Don't see what you're looking for?

See all available trips from Columbus to Isla Canas

View all trips

Isla Canas Hotel Deals

Hostal Pachamama

Isla Cañas Canas Los Santos

Fully refundableReserve now, pay when you stay

$40 nightly

$44 total

Oct 22 - Oct 23

Total with taxes and fees

10/10 Exceptional! (1 review)

"Großartige Erfahrung! Absolute Ruhe und Einsamkeit. Die Gastgeber tun alles, um den Aufenthalt zu einem wunderschönen Erlebnis werden zu lassen. Die Hütten sind sehr einfach aber es ist alles vorhanden, was man dringend braucht! Vielen Dank nochmal!!"

Reviewed on Jul 8, 2019

Villa Marina Hotel

Playa Venao Las Escobas del Venado Los Santos

$139 nightly

$156 total

Nov 11 - Nov 12

Total with taxes and fees

Selina Venao Beach East

Playa Venao 1 Las Escobas del Venado Los Santos

Fully refundableReserve now, pay when you stay

$66 nightly

$72 total

Oct 23 - Oct 24

Total with taxes and fees

See all 132 properties in Isla Canas

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.