Los Santos Vacations & Trips from $893

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Photo by Caitlyn McCrimmon

Your Los Santos Vacation

Embark on a journey full of discovery and excitement with a vacation package to Los Santos. Known for its festivals and so much more, this destination will surprise and delight at every step. A trip to Los Santos wouldn't be complete without spending some time in its best cities, starting with Pedasi. Some of the top attractions here include Iguana Island National Park and Playa El Arenal. Las Tablas is another favorite with Los Santos travelers. Visitors to this exciting city enjoy El Uverito Beach and Playa Las Comadres. Expedia has everything you need for organizing your Los Santos vacation. From flights and accommodations, to rental cars and activities, we're here to help you curate a travel experience like no other.

Top destinations in Los Santos

A wide sandy beach with gentle waves, a cloudy sky, and sparse vegetation along the shore.

Pedasí

Pedasí
A beach with waves crashing onto the shore and a person surfing in the distance.

Cambutal

Cambutal
A sandy beach with footprints, palm trees, and thatched-roof huts.

Las Escobas del Venado

Las Escobas del Venado
A sandy beach with clear turquoise water, two rocky outcrops, and a clear sky.

Las Tablas

Las Tablas
A beach with white sand and turquoise water, surrounded by palm trees.

Canas

Canas

The Latest Los Santos Vacation Packages

Price found within the past 48 hours. Click for updated prices.
Decapolis Hotel Panama City

Decapolis Hotel Panama City

San Francisco
Save 100% on your flight
$893
per person
Sep 30 - Oct 7
found 1 day ago
Roundtrip flight included
Bridgetown (BGI) to Panama City (PTY)
8.6/10 Excellent! (1,716 reviews)
Central Hotel Panama Casco Viejo

Central Hotel Panama Casco Viejo

Casco Viejo
$1,071
per person
Oct 31 - Nov 6
found 1 day ago
Roundtrip flight included
Bridgetown (BGI) to Panama City (PTY)
9.2/10 Wonderful! (1,005 reviews)
Don’t expect to be able to rest. A beautiful historic hotel in an unbeatable location BUT the hotel’s atrium is very noisy, so don’t expect to be able to rest if in an interior facing room. No late sleep ins, no napping after morning excursions and no “getting an early night”. Daily live entertainment starts as early as 8.30 am, doesn’t end until 11.00 pm and the entertainers themselves control the volume of their speakers. When we called Reception one night to complain we simply got a chuckle. Ironically, our family of 5 were assigned two “family” rooms (on different floors) yet both rooms faced the atrium (still querying why family rooms would be these?!). Based on other reviews, when we booked we specifically requested exterior rooms but of course you don’t always get what you ask for. Our stay was dampened by this and, to be honest, we are still disappointed. While we’ll be back to Casco Viejo, we will stay at a different hotel.

Reviewed on Aug 26, 2026

Megapolis Hotel Panamá

Megapolis Hotel Panamá

San Francisco
Save 100% on your flight
$1,130
per person
Sep 26 - Oct 3
found 1 day ago
Roundtrip flight included
Bridgetown (BGI) to Panama City (PTY)
8.4/10 Very Good! (1,628 reviews)
The room service was good. We got no discount voucher as promised for anything. The refrigerator was never stocked. We booked for 3 and only got 2 bottles of water at any given time. They were short on towels and rags. No valet service was available to assist with our bags in the morning of our departure as they do not have any available for early hours. The outlet mall was not bad but most stores were unoccupied so the selections were extremely limited. When we wanted to book our tours, that desk was unmanned several times before we actually got through.

Reviewed on Aug 25, 2026

Riande Aeropuerto Hotel & Casino

Riande Aeropuerto Hotel & Casino

$922
per person
Nov 7 - Nov 14
found 1 day ago
Roundtrip flight included
Bridgetown (BGI) to Panama City (PTY)
8.4/10 Very Good! (1,815 reviews)
The room was spacious and clean. Breakfast options were good, and the most important part for me was the airport shuttle, same was on time. The staff was very friendly and efficient.

Reviewed on Aug 26, 2026

Hyatt Regency Panama City

Hyatt Regency Panama City

Bella Vista
Save 100% on your flight
$1,031
per person
Nov 14 - Nov 21
found 1 day ago
Roundtrip flight included
Bridgetown (BGI) to Panama City (PTY)
9.6/10 Exceptional! (415 reviews)

Best Places to Vacation in Los Santos

1. Find your perfect Las Escobas del Venado vacation

Las Escobas del Venado in Los Santos, Panama offers the perfect atmosphere for a beach vacation. With its secluded and pristine beaches, it is an ideal destination for those looking to relax and enjoy nature. The area is also known for its great surfing opportunities, with waves that cater to both beginners and experienced surfers. Visitors can take long walks along the shoreline, bask in the warm sun, and admire breathtaking sunsets. For those seeking a lively atmosphere, there are beach bars where you can sip on refreshing drinks and soak in the vibrant marina scene.

  • Travelers tend to stay 3 days in Las Escobas del Venado

2. Escape to Pedasi with a vacation package

Pedasi in Los Santos, Panama, offers a perfect atmosphere for a beach vacation. With its stunning geographic location and beautiful beaches, it is an ideal destination for relaxation. The locals in Pedasi are known for their friendliness and welcoming nature, making visitors feel right at home. The town also offers a variety of dining options, allowing travelers to indulge in delicious local cuisine. Some popular activities for travelers to enjoy here are vacation packages that include beach activities and exploring the natural beauty of the area. Overall, Pedasi promises a memorable and enjoyable beach vacation experience.

  • The peak season is from January to March
  • The off-peak season is from August to October
  • Travelers tend to stay 3 days in Pedasi

3. Discover Las Tablas with our vacation deals

Las Tablas, located in Los Santos, Panama, is the perfect destination for a beach vacation. With its budget-friendly options and abundance of excursions, visitors can enjoy the stunning sandy beaches and crystal-clear waters. Seafood lovers will delight in the fresh and delicious seafood options available, while adventure enthusiasts can partake in activities like walking and exploring the natural parks. Las Tablas is also a family-friendly destination, offering a range of activities suitable for all ages. Whether you're looking for relaxation or adventure, Las Tablas has it all.

  • The peak season is from December to February
  • The off-peak season is from April to June
  • Travelers tend to stay 2 days in Las Tablas

4. Enjoy Cambutal with a travel package

Cambutal, located in Los Santos, Panama, offers a serene and picturesque beach vacation experience. Nestled within stunning geographic affinities, this coastal destination is perfect for relaxation and rejuvenation. With its pristine sandy beaches and crystal-clear turquoise waters, Cambutal is ideal for sunbathing, swimming, and water sports. The local atmosphere is laid-back and welcoming, allowing travelers to unwind and immerse themselves in the natural beauty of the surroundings. Whether you choose to explore the lush rainforests nearby or simply bask in the sun, Cambutal provides an idyllic beach getaway for travelers seeking tranquility and natural splendor.

  • Travelers tend to stay 4 days in Cambutal

6. Plan your dream getaway to Guanico Abajo

Guanico Abajo in Los Santos, Panama, offers a delightful beach vacation experience. With its beautiful coastline and picturesque surroundings, it is the perfect destination for relaxation and fun in the sun. The local atmosphere is laid-back and friendly, allowing travelers to immerse themselves in the tranquil vibes of this coastal town. Whether you want to lounge on the sandy beaches, go swimming in the crystal-clear waters, or explore the nearby nature reserves, Guanico Abajo has something for everyone. Experience the beauty and charm of this beach paradise during your vacation stay.

  • Travelers tend to stay 3 days in Guanico Abajo

5. Explore Canas with a vacation package

Canas, located in the beautiful region of Los Santos, Panama, offers an idyllic beach vacation experience. With its pristine white sand beaches and crystal-clear turquoise waters, it's the perfect destination for relaxation and rejuvenation. The local atmosphere is laid-back and welcoming, with friendly locals and a peaceful ambiance. Whether you want to soak up the sun, enjoy water activities like snorkeling and swimming, or simply unwind with a book by the shore, Canas has it all. Immerse yourself in the local culture, indulge in delicious seafood, and savor breathtaking sunsets over the Pacific Ocean for an unforgettable beach vacation.

  • Travelers tend to stay 2 days in Canas

Find the Best Los Santos Vacation Packages

Los Santos Essential Information

Language
Spanish
Currency
Panamanian balboas
Local Welcome
¡Hola!
Local Goodbye
Adiós
Closest Airport
Tocumen Intl. Airport (PTY)
Top Sights
Venao Beach, El Uverito Beach and Playa El Toro

Los Santos Hotel Deals

Villa Marina Hotel

Villa Marina Hotel

Playa Venao Las Escobas del Venado Los Santos
Fully refundableReserve now, pay when you stay
$135 nightly
$148 total
Aug 31 - Sep 1
Total with taxes and fees
Villa Marina Hotel
Hotel Playa Cambutal

Hotel Playa Cambutal

Calle Principal, Cambutal-Tonosi Cambutal Los Santos
Fully refundableReserve now, pay when you stay
$94 nightly
$104 total
Sep 26 - Sep 27
Total with taxes and fees
9.6/10 Exceptional! (27 reviews)
"Espectacular lugar, comida deliciosa, amenidades , ubicacion…todo excelente"

Reviewed on Jul 26, 2026

Hotel Playa Cambutal
Hotel Punta Franca

Hotel Punta Franca

Camino a Puerto Escondido Punta Mala Los Santos
Fully refundableReserve now, pay when you stay
$71 nightly
$78 total
Sep 9 - Sep 10
Total with taxes and fees
Hotel Punta Franca
See all 378 properties in Los Santos
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

How much does a Los Santos vacation package cost?
Our Los Santos packages, which begin from just $893, are an awesome way to save precious money. Select your favorite hotels, flights and more to create your ideal trip.
How do I get a cheap travel package to Los Santos?
Combine your hotel and flight bookings, throw in extras such as activities or a rental car, and save with a Los Santos vacation package. You won't just land big discounts on your adventure — you'll have a world of choice within your reach too. When you book with Expedia, you can choose from more than 550 air carriers and 1,000,000 properties globally. Your next big adventure starts right here, right now!
What are the top hotels in Los Santos?
For properties in Las Escobas del Venado with cozy beds and friendly service, you can't beat Hotel Presidente and Villa Marina Lodge And Condos. If you're swinging by Pedasi as well, you'll get a good night's sleep at Hotel Punta Franca or Selina Playa Venao - Hostel.
How far in advance should I book my Los Santos vacation?
While prices change frequently, we generally recommend reserving your seat as soon as possible. Most international airfares can be compared on Expedia up to a year in advance. If circumstances have left you booking last minute, you might still get lucky. Cheap tickets to Los Santos sometimes appear only weeks before departure.
What does an Expedia Los Santos travel package include?
Flights, hotels and a reliable car for all your fun road trip adventures. Simply select your preferred bundle and get access to great discounts. Once you've made your booking, add on some experiences and tours and watch your savings pile up. When it comes to planning your Los Santos trip, you're the boss!
What should I know before booking a Los Santos travel package?
When you book your hotels, flights and car rentals together, you'll pick up awesome discounts. Whether you're planning an island getaway in a villa or would rather stay in a fancy hotel in the city, Expedia can help make it happen.
Can I choose my airline with a Los Santos Expedia vacation package?
With a vacation package, you're the one in charge. Whether you'd like to fly to Los Santos in first class or coach, simply select from the available airline options. Expedia has access to over 550 airline partners around the world.
Does Expedia offer Book Now, Pay Later Los Santos vacation packages?
Thanks to our partnership with online lender Affirm, vacationers booking via Expedia can now pay off their journey in easy installments that won't hurt your savings. Book Now, Pay Later and begin your dream vacation today!
If I'm not able to travel, can I cancel my Los Santos vacation package?
Your situation can change suddenly, so yes, you can. You may be able to amend or cancel your Los Santos vacation package at no cost within 24 hours of booking. For bookings made more than 24 hours ago, you can still cancel or make changes, but your car rental company, airline or hotel may impose a charge. Want more information? Look up our Customer Service Portal. We're here to help make sure your getaway goes off without a hitch.

Stay near popular Los Santos attractions

A beach with a flock of seagulls on the sand and the ocean in the background.

Playa El Arenal

8.6/10 (55 reviews)
If a restful vacation is part of your travel plans, Playa El Arenal might be the perfect place to seek out during your trip to Pedasí.
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Colorful thatched-roof huts, a swimming pool, and a tropical landscape.
Photo by Isa

Los Destiladeros Beach

8.8/10 (45 reviews)
If a restful vacation is part of your travel plans, Los Destiladeros Beach might be the perfect place to seek out during your trip to Punta Mala.
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Venao Beach

9.2/10 (137 reviews)
If a restful vacation is part of your travel plans, Venao Beach might be the perfect place to seek out during your trip to Las Escobas del Venado. You can seek out the surfing spots while in the area.
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Playa El Toro

7.8/10 (42 reviews)
Why not spend a carefree afternoon at Playa El Toro during your travels in Pedasí?
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Playa Las Comadres

6.6/10 (12 reviews)
Why not spend a carefree afternoon at Playa Las Comadres during your travels in Las Tablas? Wander the seaside and parks while you're in the area.
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Iguana Island National Park

9.2/10 (48 reviews)
Explore the great outdoors at Iguana Island National Park, a lovely green space in Isla Iguana.
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* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.