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Find hotels in Isla Santa María from $40

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Compare 197 hotels, room rates, hotel reviews and availability. Most hotels are fully refundable.

Our top choices for Isla Santa María hotels

Hostal Miconia

2.5 star property
6.0 out of 10, (40)
"Mean owner"
Hostal Miconia

Hotel Galapagos Tortuga Bay

2.0 star property
7.6 out of 10, Good, (5)
"The staff were really nice, they care about each person that stays in their hotel. Highly recommend."
$165 nightly
The price is $185
Sep 4 - Sep 5
Hotel Galapagos Tortuga Bay

Capitan Max B&B

3.0 star property
9.8 out of 10, Exceptional, (179)
"The place is great and the host is very kind!"
$70 nightly
The price is $70
Sep 3 - Sep 4
Capitan Max B&B

Twin Hotel Galapagos

3.0 star property
8.4 out of 10, Very Good, (42)
"This hotle is fantastic lovely people that work here Very helpful with booking tours ect . To rooms are so fantastic, comfortable bed can’t get any better and good breakfast."
$73 nightly
The price is $73
Sep 16 - Sep 17
Twin Hotel Galapagos

Posada del Mar

3.0 star property
9.8 out of 10, Exceptional, (196)
"Great value for location."
$69 nightly
The price is $69
Sep 3 - Sep 4
Posada del Mar

Natura Gardens Galápagos Hotel

3.0 star property
7.6 out of 10, Good, (4)
$135 nightly
The price is $135
Sep 3 - Sep 4
Natura Gardens Galápagos Hotel

Hotel Fiesta

3.5 star property
9.0 out of 10, Wonderful, (364)
"Very nice place and the very large hot tub was nice to relax in after the day."
$155 nightly
The price is $155
Sep 3 - Sep 4
Hotel Fiesta

Hotel Santa Fe

4.0 star property
9.6 out of 10, Exceptional, (14)
"Beautiful hotel, with amazing staff, and great location "
$165 nightly
The price is $181
Sep 3 - Sep 4
Hotel Santa Fe

Hostal Casa Eden Galapagos

3.0 star property
8.8 out of 10, Excellent, (6)
"Great little room... walking distance from the tourist strip. Clean and comfortable. Manager was not on site when I arrived, and had to call her. The showers were pretty average and I had to request the hot water be put on. Air con worked really well. It's a budget style hostel/hotel. I'd stay there again, but with lower expectations."
$73 nightly
The price is $73
Sep 3 - Sep 4
Hostal Casa Eden Galapagos

Suymar Ecolodge Galapagos

3.0 star property
9.0 out of 10, Wonderful, (14)
"We had a lovely night at the lodge. It was a family run hotel who made us feel so welcome. The bed was huge and comfortable, the family were on hand for absolutely anything. They even came running out with umbrellas as we headed out for a walk in the rain. The food was fresh and delicious. Breakfast was served outside our room on the veranda, which was fantastic and quite simply the best omelette I have ever tasted. We arranged a pick up from the pier, which was provided at a very...
Suymar Ecolodge Galapagos

Galapagos Dreams

3.0 star property
8.8 out of 10, Excellent, (122)
"The whole team did an amazing job, and special shout out to Andy who went above and beyond to provide the best service. Jonatan has an incredible team and they made this one of the best experiences even when things did not go as planned. They were able to accommodate as much as possible in a short period of time. Hotel and tour agency staff are top notch."
$83 nightly
The price is $91
Sep 3 - Sep 4
Galapagos Dreams

Hotel La Casa de Judy

3.0 star property
9.0 out of 10, Wonderful, (157)
"The staff was nice and friendly. They were accommodating to our needs. They offered helpful suggestions to places and food locations nearby. Recommend coming here again."
$83 nightly
The price is $91
Sep 3 - Sep 4
Hotel La Casa de Judy

BAY VIEW HOUSE

3.5 star property
10.0 out of 10, Exceptional, (3)
"Connie was a great host and wonderfully helpful. Apartment is in a walkable location to everything."
$125 nightly
The price is $125
Oct 1 - Oct 2
BAY VIEW HOUSE

Angermeyer Waterfront Inn

3.5 star property
9.4 out of 10, Exceptional, (121)
"Beautiful view and very friendly staff. You do have to take a water taxi ($1 and operates 24/7) to the main part of downtown Santa Cruz but the view is worth it! Also it’s across from The Point by Midoro which as an amazing view and food. I would stay there again! "
$232 nightly
The price is $255
Sep 16 - Sep 17
Angermeyer Waterfront Inn

Hotel Palace Galapagos

3.0 star property
9.8 out of 10, Exceptional, (94)
"Everything was great. Best breakfast in Ecuador! The staff was very nice and friendly. Very convenient location."
$99 nightly
The price is $99
Oct 2 - Oct 3
Hotel Palace Galapagos

Hostal Casa Cascada

2.5 star property
10.0 out of 10, Exceptional, (2)
"I had a great time at this hostel. The owners were committed in making my trip wonderful. "
$45 nightly
The price is $45
Sep 26 - Sep 27
Hostal Casa Cascada

Lava House Hostal

3.0 star property
9.2 out of 10, Wonderful, (49)
"Had a great stay at Lava House. Clean and quiet, a small paradise in the middle of Santa Cruz. "
Lava House Hostal

Hotel Cucuve

4.0 star property
10.0 out of 10, Exceptional, (257)
"Very nice location, friendly staff "
$180 nightly
The price is $200
Sep 29 - Sep 30
Hotel Cucuve

Hostal España

3.0 star property
7.6 out of 10, Good, (119)
"Perfect location; walkable and lots of options. Will stay again."
$70 nightly
The price is $77
Sep 3 - Sep 4
Hostal España

Blu Galapagos Sustainable Waterfront Lodge

4.0 star property
8.8 out of 10, Excellent, (115)
"We had a great stay at Blu Galapagos. Loved the location and our room was perfect - Great view, well maintained and had a king bed. Even if the description says queen bed and the picture looks like a king, you can trust the picture. Morning breakfast with iguanas and seals, and all day Galapagos coffee availability made this stay special. "
$172 nightly
The price is $189
Sep 4 - Sep 5
Blu Galapagos Sustainable Waterfront Lodge
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Stay near popular Isla Santa María attractions

Punta Suarez
I've been spotted! A family of marine iguanas auditioning for meerkat manor #LifeAtExpedia

Punta Suarez

Explore the great outdoors at Punta Suarez, a lovely green space in Isla Santa María. Wander the seaside and white-sand beaches while you're in the area.

Learn more about Isla Santa María

Head to sights like Galápagos National Park and Post Office Bay as you discover Isla Santa María.

Top Isla Santa María Hotel Reviews

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