Penonome Vacations from $723

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Your Penonome Vacation

Take the hassle out of organizing your next amazing adventure with a Penonome vacation package. Whether you're visiting for its history, food or something else, this city offers endless possibilities for fun. Fill your trip to Penonome with tours of some of its top attractions. First stop? Make a beeline for 8 de Diciembre Park. Whoever you're taking time off with and whatever the size of your budget, your ultimate Penonome vacation is just a few clicks away with Expedia.

The Latest Penonome vacation packages

Price found within the past 48 hours. Click for updated prices.
Decapolis Hotel Panama City

Decapolis Hotel Panama City

4 out of 5
San Francisco
Price was $1,058, price is now $723 per person
$723
per person
Jan 19 - Jan 24
found 2 hours ago
Roundtrip flight included
Georgetown (GEO) to Panama City (PTY)
8.6/10 Excellent! (1,727 reviews)
Rooms are old and the bed is like sleeping on a piece of wood. It needs remodeling. The hallways are dirty, looks like they never vacuum. Our room did not have a lock since it was broken. Breakfast is disorganized and honestly the food is not good. Service during breakfast needs major improvement. We will not be back

Reviewed on Nov 15, 2026

Casa Mallet by Wynwood House

Casa Mallet by Wynwood House

3.5 out of 5
Casco Viejo
Price was $5,665, price is now $3,214 per person
$3,214
per person
Dec 31 - Jan 4
found 1 day ago
Roundtrip flight included
Newark Liberty Intl. Airport (EWR) to Panama City (PTY)
9.8/10 Exceptional! (30 reviews)
I would highly recommend, the service I received was impeccable and just a wonderful experience! I was a bit hesitant regarding the location but once I got there, it turned out to be perfect. The concierge staff was such a pleasure to work with especially ‘Jerry’, who provided recommendations and information. This was such a blessing to us. I would stay here again in a heart beat. It’s a must stay!

Reviewed on Sep 16, 2026

Megapolis Hotel Panamá

Megapolis Hotel Panamá

4.5 out of 5
San Francisco
Price was $1,802, price is now $1,050 per person
$1,050
per person
Feb 4 - Feb 8
found 1 day ago
Roundtrip flight included
Newark Liberty Intl. Airport (EWR) to Panama City (PTY)
8.6/10 Excellent! (1,803 reviews)

Central Hotel Panama Casco Viejo

Central Hotel Panama Casco Viejo

4 out of 5
Casco Viejo
Price was $2,776, price is now $1,633 per person
$1,633
per person
Dec 18 - Dec 22
found 1 day ago
Roundtrip flight included
Newark Liberty Intl. Airport (EWR) to Panama City (PTY)
9.2/10 Wonderful! (1,015 reviews)

Casa Lefevre By Wynwood House

Casa Lefevre By Wynwood House

3 out of 5
Casco Viejo
Price was $4,189, price is now $2,498 per person
$2,498
per person
Dec 31 - Jan 4
found 1 day ago
Roundtrip flight included
Newark Liberty Intl. Airport (EWR) to Panama City (PTY)
9.6/10 Exceptional! (16 reviews)

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Stay near popular Penonome attractions

Penonomena History and Tradition Museum

7.6/10 (4 reviews)
You can spend time exploring the galleries in Penonomena History and Tradition Museum during your travels in Penonome. Amble around the area's parks or experience its museums.
See properties

What to do in Penonome

Canopy- Anton Valley

Zip line Canopy Adventures in Anton Valley

$195
per adult
Zip line Canopy Adventures in Anton Valley
See all activities in Penonome

Penonome Hotel Deals

Hotel Coclé

Hotel Coclé

3.5 out of 5
Via Interamericana Penonome Cocle
Fully refundableReserve now, pay when you stay
$72 nightly
The price is $79 total per night from Nov 16 to Nov 17
$79 total
Nov 16 - Nov 17
Total with taxes and fees
8.6/10 Excellent! (273 reviews)
"Ok"

Reviewed on Nov 13, 2026

Hotel Coclé
Hotel Riu Playa Blanca - All Inclusive

Hotel Riu Playa Blanca - All Inclusive

3.5 out of 5
Finca 43.668 Rio Hato Cocle
8.2/10 Very Good! (1,000 reviews)
"Desayuno no tenía variedad. Solo comida para Colombia"

Reviewed on Nov 11, 2026

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Hotel Riu Playa Blanca - All Inclusive
Grand Decameron Panama, A Trademark Resort

Grand Decameron Panama, A Trademark Resort

3.5 out of 5
Avenida Principal Farallon Kilometro 115 Rio Hato Cocle
Fully refundableReserve now, pay when you stay
$156 nightly
The price is $172 total per night from Nov 26 to Nov 27
$172 total
Nov 26 - Nov 27
Total with taxes and fees
7.4/10 Good! (1,000 reviews)
"The room is clean and tidy, comfortable and quiet."

Reviewed on Nov 12, 2026

Grand Decameron Panama, A Trademark Resort
See all 305 properties in Penonome
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find the Best Penonome Vacation Packages

Penonome Essential Information

Language
Spanish
Currency
Panamanian balboas
Local Welcome
¡Hola!
Local Goodbye
Adiós
Population
16,300
Max Temp Winter
85ºF
Max Temp Summer
85ºF
Top Sights
Mercado de Artesanías La Pintada and 8 de Diciembre Park

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Frequently asked questions

Is Penonome better suited for a beach vacation or a cultural trip?
Penonome is primarily a beach and outdoor destination, offering plenty of opportunities for relaxation by the water and exploring nature. You'll find several popular coastal spots like Playa Blanca, about 24 miles from central Penonome, perfect for enjoying the sun and sand.

Beyond the beaches, the area also provides options for outdoor adventures at places like El Cope National Park, located about 26 miles away. For those interested in history, cultural sites such as the Church of Nata de los Caballeros, about 18 miles from central Penonome, offer a glimpse into the region's past.
How can I save money on a Penonome vacation package?
When you bundle, you can save up to 30%*. To save money on a Penonome package, consider traveling during the quieter months or be flexible with your dates to find more options. Bundling your flights and hotel together often unlocks savings compared to booking separately. *Members only. Savings vary.
What are the top things to do in Penonome?
A Penonome vacation offers a blend of beautiful beaches, natural parks, and cultural insights:

Browse and book things to do in Penonome on Expedia.
Do you need to rent a car in Penonome, or is public transport enough?
For exploring Penonome and its surrounding attractions, a rental car offers the most flexibility. As an outdoor and nature destination outside the city, Penonome has many highlights that are spread out. For instance, popular beaches like Playa Blanca are about 24 miles away, and natural areas such as El Cope National Park are about 26 miles from central Penonome.

While a car is ideal for day trips, if your Penonome vacation package focuses on a resort stay with on-site dining and activities, you might not need a car for daily needs. However, transfers from Panama City (PTY-Tocumen Intl.) Airport, located about 77 miles away, would still require pre-arranged transport or a taxi. For those planning Penonome beach vacation packages and wanting to explore beyond their resort, a rental car is highly recommended.
Can I change or cancel my Penonome vacation package if my plans change?
Yes, you can cancel your vacation package via your itinerary page on Expedia or by contacting customer service. Remember that some packages are fully refundable, but the details vary based on each unique booking. A fully refundable package may depend on how far out from the travel dates you're canceling and what airline you are traveling with.
Do One Key members get extra savings when booking Penonome vacation packages?
Yes, members who join our free One Key™ travel rewards program can instantly unlock additional savings and save 10% or more on over 500,000 stays worldwide with Member Prices and over 1 million car rentals.
Does Expedia offer Book Now, Pay Later Penonome vacation packages?
Yes, with Expedia's Book Now, Pay Later option, powered by Affirm, you can spread the cost of your Penonome vacation over 3, 6, or 12 months. With no late payment fees or hidden costs, it's easy to secure your ideal vacation package as soon as you spot it.
How do I find last-minute vacation packages to Penonome?
To find last-minute vacation packages to Penonome, explore the last-minute deals section for the latest package offers, including flights, departing in the coming weeks. Being flexible with your travel dates and hotel preferences can help you secure the best prices.
How does free cancellation work on Penonome vacation packages?
Free cancellation on a Penonome vacation package depends on the specific hotel and rate combination you book. Many bookings allow free cancellation up to a stated deadline (often a few days before travel) where eligible. Read the cancellation terms carefully when reviewing the package, and visit Expedia help center for further details.
Is it cheaper to book a Penonome vacation as a package or separately?
Booking flights and hotels together can unlock lower overall prices. Better still, you can tailor your Penonome getaway to match your exact preference. Pick your preferred flight time, select the hotel type and add a car rental. Explore our bundles to see how much you can save.
Why should I book my Penonome vacation package with Expedia?
Booking your vacation package on Expedia makes it easier to get more out of your trip from the start. With a wide choice of hotels, you can compare prices, reviews and amenities all in one place, then bundle your hotel with flights which could help you save even more. Flexible booking options on selected stays also make it easier to plan with confidence.

Explore a world of travel with Expedia

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.