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Compare 12 B&B in Santee with updated reviews, rates, and availability.

Twelve Senses Retreat, a member of Design Hotels

4.0 star property
10.0 out of 10, Exceptional, (30)
"Anka, was just wonderful and caring. So attentive to our needs and welcoming. Thank you for a wonderful stay. Beautiful property."
$365 nightly
The price is $402
Jun 22 - Jun 23
Total includes taxes and fees
Twelve Senses Retreat, a member of Design Hotels

Cardiff by the Sea Lodge

3.0 star property
8.4 out of 10, Very Good, (698)
"It was cozy and clean and great location and great customer service "
$199 nightly
The price is $219
Jun 17 - Jun 18
Total includes taxes and fees
Cardiff by the Sea Lodge

Inn at Moonlight Beach

3.5 star property
9.6 out of 10, Exceptional, (107)
"Such a serene and grounded a place to stay, I enjoyed it very much and hope to visit again"
$249 nightly
The price is $271
Jun 18 - Jun 19
Total includes taxes and fees
Inn at Moonlight Beach

Secret Garden Inn

3.0 star property
8.6 out of 10, Excellent, (111)
"Beautiful service and clean. Patricia was wonderful/ We loved our stay."
$239 nightly
The price is $270
Jun 17 - Jun 18
Total includes taxes and fees
Secret Garden Inn

1906 Lodge

3.5 star property
9.8 out of 10, Exceptional, (792)
"Beautiful historic hotel; friendly and professional staff"
$269 nightly
The price is $297
Jun 17 - Jun 18
Total includes taxes and fees
1906 Lodge
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Frequently asked questions

What is the nightly rate for a Bed & Breakfast in Santee?
Prices for B&Bs in Santee often vary, but you can find a great deal from $57 with Expedia. All sorts of factors affect price, such as location and the time of year. It usually costs more to stay at Santee B&Bs over the weekend too. Travelers can find the best deals by being flexible with their dates, and by using our filters to sort prices from low to high.
When is the best time to book a Bed & Breakfast in Santee?
The best time to book a B&B in Santee is during the spring months of March through May, when the climate is pleasantly warm and ideal for outdoor activities. This period welcomes comfortable temperatures ranging from the mid-60s to the low 80s Fahrenheit, superb for enjoying Santee’s beautiful parks and scenic trails. As visitors take in the lush landscapes, they can also engage in popular activities like hiking, biking, and birdwatching, all while soaking in the vibrant colors of blooming flora.

April stands out as a particularly appealing month to visit, as the weather is delightful for exploring the nearby Santee Lakes, where families can enjoy picnics, fishing, and leisurely strolls along the water’s edge. The environment is lively yet not overly crowded, allowing for an easy experience while taking in the natural beauty.

If you’re looking to travel on a budget, consider planning your trip for October. This month offers a quieter atmosphere, making it an excellent time for those who prefer solitude and reflection while still enjoying the lovely autumn scenery. Visitors can relish the temperate climate and partake in local events without the hustle and bustle of peak season.
What is the difference between a Santee Bed and Breakfast and a hotel?
Every Santee B&B has its own unique feel. Whether it’s a cozy reading space or a sunlit breakfast nook to enjoy your morning cup of coffee, the quaint details are what make bed and breakfasts a home away from home. Travelers can look forward to personal touches, thoughtful amenities and of course a scrumptious breakfast at Santee B&Bs.