Title: Santee Vacation Rentals from $109: Search Short-Term Rentals | Expedia.com

[Santee Travel Guide](https://expedia.com/Santee.dx6678)[Hotels in Santee](https://expedia.com/Santee-Hotels.d6678.Travel-Guide-Hotels)[Flights to Santee](https://expedia.com/Cheap-Flights-To-Santee.d6678.Travel-Guide-Flights)[Things to do in Santee](https://expedia.com/Things-To-Do-In-Santee.d6678.Travel-Guide-Activities)[Car Rentals in Santee](https://expedia.com/Car-Rentals-In-Santee.d6678.Car-Rental-Guide)[Santee Vacation Packages](https://expedia.com/Santee.d6678.Destination-Travel-Guides)

![](https://images.trvl-media.com/place/3073/47ddac67-5969-41c0-8843-96304c5986bd.jpg?impolicy=fcrop&w=1200&h=500&q=medium)

![](https://images.trvl-media.com/place/3073/47ddac67-5969-41c0-8843-96304c5986bd.jpg?impolicy=fcrop&w=1200&h=500&q=medium)

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## Check prices for these dates

In two weeks

[Apr 10 - Apr 12](https://www.expedia.com/Hotel-Search?regionId=6678&startDate=2026-04-10&endDate=2026-04-12&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

In two months

[May 22 - May 24](https://www.expedia.com/Hotel-Search?regionId=6678&startDate=2026-05-22&endDate=2026-05-24&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

In three months

[Jun 19 - Jun 21](https://www.expedia.com/Hotel-Search?regionId=6678&startDate=2026-06-19&endDate=2026-06-21&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

In four months

[Jul 17 - Jul 19](https://www.expedia.com/Hotel-Search?regionId=6678&startDate=2026-07-17&endDate=2026-07-19&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

## Our top choices for Santee vacation rentals

![Beach towels](https://images.trvl-media.com/lodging/94000000/93250000/93245900/93245882/a981e220.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/94000000/93250000/93245900/93245882/e03e7f6a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior detail](https://images.trvl-media.com/lodging/94000000/93250000/93245900/93245882/e3ba4b42.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Terrace/patio](https://images.trvl-media.com/lodging/94000000/93250000/93245900/93245882/df13d4b7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Adorable 1 bedroom house 8 min from La Jolla!

[](https://www.expedia.com/San-Diego-Hotels-Adorable-1-Bedroom-House-8-Minutes-From-La-Jolla.h93245882.Hotel-Information)

Bay Ho

10/10

Exceptional

(49 reviews)

"The home is beautiful, everything was fantastic! The hosts were very helpful and accommodating. The location was convenient and quiet. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Paulina B.

$221 nightly

$246 total

Apr 6 - Apr 7

Total with taxes and fees

[](https://www.expedia.com/San-Diego-Hotels-Adorable-1-Bedroom-House-8-Minutes-From-La-Jolla.h93245882.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/94000000/93160000/93155000/93154964/94ac6ddc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Outdoor dining](https://images.trvl-media.com/lodging/94000000/93160000/93155000/93154964/a8e449da.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/94000000/93160000/93155000/93154964/4a5fdc43.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![2 bedrooms, desk, iron/ironing board, travel crib](https://images.trvl-media.com/lodging/94000000/93160000/93155000/93154964/4d00ed8b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Harley Davidson Ranch Glampling & Kids Play Area

[](https://www.expedia.com/Ramona-Hotels-Harley-Davidson-Ranch-Glampling.h93154964.Hotel-Information)

Ramona

10/10

Exceptional

(11 reviews)

"It was a pleasure staying here! the place clean and cozy and we hope to return soon!"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Flor R.

$227 nightly

$242 total

Mar 29 - Mar 30

Total with taxes and fees

[](https://www.expedia.com/Ramona-Hotels-Harley-Davidson-Ranch-Glampling.h93154964.Hotel-Information)

![Terrace/patio](https://images.trvl-media.com/lodging/120000000/119380000/119376100/119376070/w507h683x259y0-415b5dc7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Microwave, oven, paper towels](https://images.trvl-media.com/lodging/120000000/119380000/119376100/119376070/w506h683x259y0-bc7fb2a4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Iron/ironing board, WiFi, bed sheets](https://images.trvl-media.com/lodging/120000000/119380000/119376100/119376070/ffe7db94.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/120000000/119380000/119376100/119376070/b679354d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Grand Studio with exclusive resort amenities.

[](https://www.expedia.com/Alpine-Hotels-Grand-Studio-With-Exclusive-Resort-Amenities.h119376070.Hotel-Information)

Alpine

10/10

Exceptional

(3 reviews)

"This was such a beautiful and peaceful spot — quiet, super adorable, and truly a must-stay when coming into town! The host was incredibly helpful and responsive, which made everything feel effortless. The room itself was quaint, very clean, and had such a cozy charm that made it easy to relax and unwind.I would absolutely stay here again and highly recommend it to anyone looking for a comfortable and delightful place to stay!"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Heather S.

$283 nightly

$283 total

Mar 29 - Mar 30

Total with taxes and fees

[](https://www.expedia.com/Alpine-Hotels-Grand-Studio-With-Exclusive-Resort-Amenities.h119376070.Hotel-Information)

![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/107000000/106660000/106656300/106656297/30e3d4c7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/107000000/106660000/106656300/106656297/4c69726c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Outdoor dining](https://images.trvl-media.com/lodging/107000000/106660000/106656300/106656297/6dbb06e4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property grounds](https://images.trvl-media.com/lodging/107000000/106660000/106656300/106656297/41801063.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Beautiful Normal Heights Living

[](https://www.expedia.com/San-Diego-Hotels-Beautiful-Normal-Heights-Living.h106656297.Hotel-Information)

Mid-City

10/10

Exceptional

(78 reviews)

"Great location, nice cozy place, had everything we needed. Would definitely stay again."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Sheila S.

$286 nightly

$318 total

Mar 29 - Mar 30

Total with taxes and fees

[](https://www.expedia.com/San-Diego-Hotels-Beautiful-Normal-Heights-Living.h106656297.Hotel-Information)

![Terrace/patio](https://images.trvl-media.com/lodging/97000000/96950000/96948400/96948311/9247fa24.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![1 bedroom, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/97000000/96950000/96948400/96948311/cbaffc10.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/97000000/96950000/96948400/96948311/f5946c6f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/97000000/96950000/96948400/96948311/6721fe0d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Wine Country Cabin Near San Diego - on private 9 acres 

[](https://www.expedia.com/Ramona-Hotels-Wine-Country-Cabin-Near-San-Diego-On-Private-9-Acres.h96948311.Hotel-Information)

Ramona

9.4/10

Exceptional

(22 reviews)

"Well equipped kichenette with large toaster oven, microwave, fridge and electric griddle/hot plate was great for quick meals. We appreciated the candle and blankets available for hanging out on the deck at night. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Megan G.

[](https://www.expedia.com/Ramona-Hotels-Wine-Country-Cabin-Near-San-Diego-On-Private-9-Acres.h96948311.Hotel-Information)

![Smart TV](https://images.trvl-media.com/lodging/109000000/108600000/108593500/108593412/41d1b5c6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Dining](https://images.trvl-media.com/lodging/109000000/108600000/108593500/108593412/170fbed5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Outdoor dining](https://images.trvl-media.com/lodging/109000000/108600000/108593500/108593412/108847dd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/109000000/108600000/108593500/108593412/02c10b6c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### 'Ted' 2-bedroom cozy house in central location! 10 minutes to Balboa!

[](https://www.expedia.com/San-Diego-Hotels-Ted-2-Bedroom-Cozy-House-In-Central-Location-10-Minutes-To-Balboa.h108593412.Hotel-Information)

Encanto

8.8/10

Excellent

(32 reviews)

"This was a good central location and convenient to all of San Diego, both in and out of town."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Samuel B.

$210 nightly

$234 total

Mar 29 - Mar 30

Total with taxes and fees

[](https://www.expedia.com/San-Diego-Hotels-Ted-2-Bedroom-Cozy-House-In-Central-Location-10-Minutes-To-Balboa.h108593412.Hotel-Information)

![Smart TV, books](https://images.trvl-media.com/lodging/19000000/18790000/18785800/18785721/397f7d78.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/19000000/18790000/18785800/18785721/e1c0f5bb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/19000000/18790000/18785800/18785721/ce033b33.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/19000000/18790000/18785800/18785721/9c85143c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Cozy Pacific Beach Cottage w/Bikes, Private Yard & Entrance

[](https://www.expedia.com/San-Diego-Hotels-Cozy-Pacific-Beach-Cottage-WBikes.h18785721.Hotel-Information)

Pacific Beach

9.6/10

Exceptional

(54 reviews)

"Second stay and we’ll be back !! Good location, owner easy to work with, clean & tidy !!"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Kevin O.

$265 nightly

$295 total

Mar 30 - Mar 31

Total with taxes and fees

[](https://www.expedia.com/San-Diego-Hotels-Cozy-Pacific-Beach-Cottage-WBikes.h18785721.Hotel-Information)

![Property grounds](https://images.trvl-media.com/lodging/45000000/44830000/44828500/44828462/11b9359d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Outdoor pool](https://images.trvl-media.com/lodging/45000000/44830000/44828500/44828462/62222fd0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/45000000/44830000/44828500/44828462/33d4acad.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/45000000/44830000/44828500/44828462/a181a393.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Hilltop cabin with panoramic lake & mountain views

[](https://www.expedia.com/Escondido-Hotels-Hilltop-Cabin-With-Panoramic-Lake-Mountain-Views.h44828462.Hotel-Information)

Del Dios

9.4/10

Exceptional

(30 reviews)

"Beautiful property, comfy cabin"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Robert S.

$192 nightly

$192 total

Apr 7 - Apr 8

Total with taxes and fees

[](https://www.expedia.com/Escondido-Hotels-Hilltop-Cabin-With-Panoramic-Lake-Mountain-Views.h44828462.Hotel-Information)

![Terrace/patio](https://images.trvl-media.com/lodging/99000000/98260000/98255100/98255024/6fb9a0ee.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/99000000/98260000/98255100/98255024/63087c12.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/99000000/98260000/98255100/98255024/w1024h680x0y0-28b34f88.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Smart TV](https://images.trvl-media.com/lodging/99000000/98260000/98255100/98255024/cfa18b2c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Private 2 bedroom apt in new craftsman ranch!

[](https://www.expedia.com/Escondido-Hotels-Private-2-Bedroom-Apt-In-New-Craftsman-Ranch.h98255024.Hotel-Information)

Escondido

10/10

Exceptional

(15 reviews)

"We really enjoyed our stay! The amenities were great, the view and scenery were beautiful, and the property was very family-friendly. Would definitely recommend and stay again!"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Joshua D.

$271 nightly

$290 total

Apr 7 - Apr 8

Total with taxes and fees

[](https://www.expedia.com/Escondido-Hotels-Private-2-Bedroom-Apt-In-New-Craftsman-Ranch.h98255024.Hotel-Information)

![Rooftop terrace](https://images.trvl-media.com/lodging/115000000/114120000/114116400/114116366/dd5fc603.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Premium bedding, pillowtop beds, desk, laptop workspace](https://images.trvl-media.com/lodging/115000000/114120000/114116400/114116366/6521c599.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![55-inch flat-screen TV with cable channels, Netflix, Hulu](https://images.trvl-media.com/lodging/115000000/114120000/114116400/114116366/4123f91e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Premium bedding, pillowtop beds, desk, laptop workspace](https://images.trvl-media.com/lodging/115000000/114120000/114116400/114116366/b4a5f1e3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Sentral Gaslamp Quarter

[](https://www.expedia.com/San-Diego-Hotels-Sentral-Gaslamp-Quarter.h114116366.Hotel-Information)

Downtown San Diego

9.4/10

Exceptional

(799 reviews)

"Great location"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Ethan

$164 nightly

$190 total

Apr 2 - Apr 3

Total with taxes and fees

[](https://www.expedia.com/San-Diego-Hotels-Sentral-Gaslamp-Quarter.h114116366.Hotel-Information)

![1 bedroom, desk, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/28000000/27750000/27747700/27747629/1081d63f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Bathtub, hair dryer, towels](https://images.trvl-media.com/lodging/28000000/27750000/27747700/27747629/057aea62.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Smart TV](https://images.trvl-media.com/lodging/28000000/27750000/27747700/27747629/21b6c135.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![A heated pool](https://images.trvl-media.com/lodging/28000000/27750000/27747700/27747629/2adffe31.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Luxurious La Costa Remodel by SPA w/Steam Shower and Washer/Dryer!

[](https://www.expedia.com/Carlsbad-Hotels-Luxurious-La-Costa-Remodel-By-SPA-Wsteam-Shower-And-Washerdryer.h27747629.Hotel-Information)

La Costa

10/10

Exceptional

(65 reviews)

"Great location comfy beds will definitely book again"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Valerie E.

$291 nightly

$322 total

Mar 30 - Mar 31

Total with taxes and fees

[](https://www.expedia.com/Carlsbad-Hotels-Luxurious-La-Costa-Remodel-By-SPA-Wsteam-Shower-And-Washerdryer.h27747629.Hotel-Information)

![Property grounds](https://images.trvl-media.com/lodging/97000000/96150000/96148200/96148191/c1e5320d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property grounds](https://images.trvl-media.com/lodging/97000000/96150000/96148200/96148191/dc7e347e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Smart TV](https://images.trvl-media.com/lodging/97000000/96150000/96148200/96148191/w1421h960x18y0-15435e0d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/97000000/96150000/96148200/96148191/829373e3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Studio near San Diego attraction with amazing view

[](https://www.expedia.com/Escondido-Hotels-Studio-Near-San-Diego-Attraction-With-Amazing-View.h96148191.Hotel-Information)

Country Club

9.4/10

Exceptional

(12 reviews)

"Was a very nice place to stay! 10/10 will be staying again sometime in the future! Felt very safe. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Kimberly g.

$155 nightly

$161 total

Mar 29 - Mar 30

Total with taxes and fees

[](https://www.expedia.com/Escondido-Hotels-Studio-Near-San-Diego-Attraction-With-Amazing-View.h96148191.Hotel-Information)

![Terrace/patio](https://images.trvl-media.com/lodging/109000000/108710000/108701900/108701869/48c8f0a2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/109000000/108710000/108701900/108701869/794b6171.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property grounds](https://images.trvl-media.com/lodging/109000000/108710000/108701900/108701869/c70269c5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![2 bedrooms, iron/ironing board, WiFi, bed sheets](https://images.trvl-media.com/lodging/109000000/108710000/108701900/108701869/w1856h1211x1y1-d6903676.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Breathtaking retreat in the wine country on the ranch with goats you can pet! 

[](https://www.expedia.com/Poway-Hotels-Breathtaking-Retreat-In-The-Wine-Country-Close-To-Safari-Park.h108701869.Hotel-Information)

Escondido

10/10

Exceptional

(13 reviews)

"Gorgeous view, very responsive host. We enjoyed our stay and would recommend "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Carol

$366 nightly

$366 total

Apr 16 - Apr 17

Total with taxes and fees

[](https://www.expedia.com/Poway-Hotels-Breathtaking-Retreat-In-The-Wine-Country-Close-To-Safari-Park.h108701869.Hotel-Information)

![Pool](https://images.trvl-media.com/lodging/124000000/123120000/123119500/123119491/81fcef29.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Terrace/patio](https://images.trvl-media.com/lodging/124000000/123120000/123119500/123119491/41d43e51.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/124000000/123120000/123119500/123119491/dd8dcac5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/124000000/123120000/123119500/123119491/5e1dd234.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Cozy & romantic tiny house w/magnificent views, hillside pool, & adorable goats

[](https://www.expedia.com/Escondido-Hotels-Cozy-Romantic-Tiny-House-Wmagnificent-Views.h123119491.Hotel-Information)

Del Dios

10/10

Exceptional

(1 review)

"The view is everything! place is very cute and clean"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Basel

$294 nightly

$294 total

Apr 9 - Apr 10

Total with taxes and fees

[](https://www.expedia.com/Escondido-Hotels-Cozy-Romantic-Tiny-House-Wmagnificent-Views.h123119491.Hotel-Information)

![Terrace/patio](https://images.trvl-media.com/lodging/89000000/88940000/88939600/88939547/95b13715.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/89000000/88940000/88939600/88939547/2028d196.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![1 bedroom, free WiFi, bed sheets](https://images.trvl-media.com/lodging/89000000/88940000/88939600/88939547/w1338h1004x3y2-43e3489f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Fridge, microwave, oven, coffee/tea maker](https://images.trvl-media.com/lodging/89000000/88940000/88939600/88939547/2a57dcd5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Vintage Airstream Trailer in the Hills of San Marcos!

[](https://www.expedia.com/San-Marcos-Hotels-Vintage-Airstream-Trailer-In-The-Hills-Of-San-Marcos.h88939547.Hotel-Information)

San Marcos

9.8/10

Exceptional

(36 reviews)

"Very comfy great experience will definitely go again "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Stephanie F.

$230 nightly

$230 total

Mar 28 - Mar 29

Total with taxes and fees

[](https://www.expedia.com/San-Marcos-Hotels-Vintage-Airstream-Trailer-In-The-Hills-Of-San-Marcos.h88939547.Hotel-Information)

![Terrace/patio](https://images.trvl-media.com/lodging/106000000/105770000/105768500/105768475/a1a196de.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![3 bedrooms, desk, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/106000000/105770000/105768500/105768475/47e183ff.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/106000000/105770000/105768500/105768475/e5bd25d1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/106000000/105770000/105768500/105768475/0215ac4a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Family Friendly Modern Guest House

[](https://www.expedia.com/San-Diego-Hotels-Newly-Built.h105768475.Hotel-Information)

Mira Mesa

10/10

Exceptional

(14 reviews)

"Wonderful modern, clean and well-appointed property! Will definitely consider staying here in the future!"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Derek W.

$462 nightly

$513 total

Apr 1 - Apr 2

Total with taxes and fees

[](https://www.expedia.com/San-Diego-Hotels-Newly-Built.h105768475.Hotel-Information)

![Property grounds](https://images.trvl-media.com/lodging/19000000/19000000/18992900/18992847/209c4e9c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/19000000/19000000/18992900/18992847/39852d73.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Outdoor dining](https://images.trvl-media.com/lodging/19000000/19000000/18992900/18992847/35623cec.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![1 bedroom, iron/ironing board, travel crib, WiFi](https://images.trvl-media.com/lodging/19000000/19000000/18992900/18992847/7e95c61c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Adorable 1 bd cottage, heart of Old Town-- WE LOVE PETS! Insta @oldtownvacay

[](https://www.expedia.com/San-Diego-Hotels-Adorable-1-Bd-Cottage.h18992847.Hotel-Information)

Old Town San Diego

10/10

Exceptional

(273 reviews)

"We enjoyed our time in the back cottage. Everything we needed was available. We were able to just walk to so many sites and restaurants. Will definitely try to come back again! "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Phillip

$216 nightly

$240 total

Apr 7 - Apr 8

Total with taxes and fees

[](https://www.expedia.com/San-Diego-Hotels-Adorable-1-Bd-Cottage.h18992847.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/94000000/93160000/93159800/93159719/abf7bf50.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/94000000/93160000/93159800/93159719/w1024h679x0y2-3dfcbe05.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![1 bedroom, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/94000000/93160000/93159800/93159719/w1024h678x0y2-e893bd51.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Food and drink](https://images.trvl-media.com/lodging/94000000/93160000/93159800/93159719/w1024h675x0y4-a79ff01d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Casita Vino - Dog-Friendly Vineyard Retreat & Stay 

[](https://www.expedia.com/Escondido-Hotels-Casita-Vino-Dog-Friendly-Vineyard-Retreat-Stay.h93159719.Hotel-Information)

West Ridge

9.6/10

Exceptional

(20 reviews)

"Wonderful location super pet friendly, will definitely rebook!"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Daphne E.

$238 nightly

$238 total

Mar 29 - Mar 30

Total with taxes and fees

[](https://www.expedia.com/Escondido-Hotels-Casita-Vino-Dog-Friendly-Vineyard-Retreat-Stay.h93159719.Hotel-Information)

![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/109000000/108210000/108204200/108204148/c8eea6ea.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/109000000/108210000/108204200/108204148/c2710c8a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![TV, fireplace, DVD player, books](https://images.trvl-media.com/lodging/109000000/108210000/108204200/108204148/e644d865.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![4 bedrooms, desk, iron/ironing board, WiFi](https://images.trvl-media.com/lodging/109000000/108210000/108204200/108204148/b49bfa38.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Pristine Poway Retreat

[](https://www.expedia.com/Poway-Hotels-Pristine-Poway-Retreat.h108204148.Hotel-Information)

Poway

9.0/10

Wonderful

(15 reviews)

"Beautiful place, responsive host and nice location. Kitchen needs pots/pans and other cooking items like a cutting board"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Terri K.

$511 nightly

$511 total

Mar 29 - Mar 30

Total with taxes and fees

[](https://www.expedia.com/Poway-Hotels-Pristine-Poway-Retreat.h108204148.Hotel-Information)

![Lobby sitting area](https://images.trvl-media.com/lodging/105000000/104290000/104283900/104283827/f051791c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Desk, laptop workspace, free WiFi, bed sheets](https://images.trvl-media.com/lodging/105000000/104290000/104283900/104283827/e8d02919.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Desk, laptop workspace, free WiFi, bed sheets](https://images.trvl-media.com/lodging/105000000/104290000/104283900/104283827/b278e0ed.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Studio Room, 1 Queen Bed (East - Freeway Facing) | Desk, laptop workspace, free WiFi, bed sheets](https://images.trvl-media.com/lodging/105000000/104290000/104283900/104283827/61427440.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Uptown Inn by Vantaggio - Limited Service Apart-Hotel

[](https://www.expedia.com/San-Diego-Hotels-Uptown-Inn.h104283827.Hotel-Information)

Hillcrest

8.4/10

Very Good

(325 reviews)

"It is a clean place to stay and budget friendly. Unfortunately the noise from the road can make it hard to sleep."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Afia

$112 nightly

$126 total

Apr 21 - Apr 22

Total with taxes and fees

[](https://www.expedia.com/San-Diego-Hotels-Uptown-Inn.h104283827.Hotel-Information)

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

[View all properties](https://expedia.com/Hotel-Search?startDate=2026-04-09&endDate=2026-04-10&regionId=6678&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&openPlayBack=true)

## Find vacation rentals that suit your style

Cabins

[](https://www.expedia.com/Hotel-Search?destination=Santee%2C+California%2C+United+States+of+America&regionId=6678&latLong=32.838383%2C-116.973915&adults=2&startDate=2026-06-23&d1=2026-06-23&endDate=2026-06-26&d2=2026-06-26&lodging=CABIN)

Private vacation homes

[](https://www.expedia.com/Hotel-Search?destination=Santee%2C+California%2C+United+States+of+America&regionId=6678&latLong=32.838383%2C-116.973915&adults=2&startDate=2026-06-23&d1=2026-06-23&endDate=2026-06-26&d2=2026-06-26&lodging=VACATION_HOME)

Apartments

[](https://www.expedia.com/Hotel-Search?destination=Santee%2C+California%2C+United+States+of+America&regionId=6678&latLong=32.838383%2C-116.973915&adults=2&startDate=2026-06-23&d1=2026-06-23&endDate=2026-06-26&d2=2026-06-26&lodging=APARTMENT)

Aparthotels

[](https://www.expedia.com/Hotel-Search?destination=Santee%2C+California%2C+United+States+of+America&regionId=6678&latLong=32.838383%2C-116.973915&adults=2&startDate=2026-06-23&d1=2026-06-23&endDate=2026-06-26&d2=2026-06-26&lodging=APART_HOTEL)

Condos

[](https://www.expedia.com/Hotel-Search?destination=Santee%2C+California%2C+United+States+of+America&regionId=6678&latLong=32.838383%2C-116.973915&adults=2&startDate=2026-06-23&d1=2026-06-23&endDate=2026-06-26&d2=2026-06-26&lodging=CONDO)

Cottages

[](https://www.expedia.com/Hotel-Search?destination=Santee%2C+California%2C+United+States+of+America&regionId=6678&latLong=32.838383%2C-116.973915&adults=2&startDate=2026-06-23&d1=2026-06-23&endDate=2026-06-26&d2=2026-06-26&lodging=COTTAGE)

Villas

[](https://www.expedia.com/Hotel-Search?destination=Santee%2C+California%2C+United+States+of+America&regionId=6678&latLong=32.838383%2C-116.973915&adults=2&startDate=2026-06-23&d1=2026-06-23&endDate=2026-06-26&d2=2026-06-26&lodging=VILLA)

Houseboats

[](https://www.expedia.com/Hotel-Search?destination=Santee%2C+California%2C+United+States+of+America&regionId=6678&latLong=32.838383%2C-116.973915&adults=2&startDate=2026-06-23&d1=2026-06-23&endDate=2026-06-26&d2=2026-06-26&lodging=HOUSE_BOAT)

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## Top Santee Hotel Reviews

![Days Inn by Wyndham San Diego Hotel Circle](https://images.trvl-media.com/lodging/1000000/20000/19300/19220/c491024e_y.jpg)

### Days Inn by Wyndham San Diego Hotel Circle

10/10 Excellent

"Easy check in & out. Great parking. Super clean & comfy bed & great big bathroom "

[](https://expedia.com/San-Diego-Hotels-Days-Inn-By-Wyndham-San-Diego-Hotel-Circle.h19220.Hotel-Information)

![The Sofia Hotel](https://images.trvl-media.com/lodging/2000000/1580000/1573900/1573807/bd726404_y.jpg)

### The Sofia Hotel

2/10 Terrible

"I booked a room to stay here for the weekend because of its great prices. I wish I wouldve paid more and stayed somewhere else. I arrived to the hotel around 2pm aware that check in was at 4pm. Droppes mt bags off, returned at 7 to find out my room was still not ready. I booked a room for 3 people, in return I was given a room with 1 bed until my room was ready at 9pm. Noone came to help take my bags to the new room. I was just left with a bag cart to do it myself. Once I arrived in the correct room, I found blood on the pull out bed sheets. House keeping came to remove the bedding but only to replace it with a mattress cover, no sheets. I had to call again to have housekeeping come make up the bed. Terrible service. "

[](https://expedia.com/San-Diego-Hotels-The-Sofia-Hotel.h1573807.Hotel-Information)

![Best Western Seven Seas](https://images.trvl-media.com/lodging/1000000/10000/1800/1734/w3837h2556x3y3-8b148daf_y.jpg)

### Best Western Seven Seas

10/10 Excellent

"Our second time staying at this location we loved it. Jennifer was helpful with nearby restaurant favorites as well as the on sire dining. We hope to return in the summer. "

[](https://expedia.com/San-Diego-Hotels-Best-Western-Seven-Seas.h1734.Hotel-Information)

![Wyndham San Diego Bayside](https://images.trvl-media.com/lodging/1000000/20000/11200/11177/a77f85c3_y.jpg)

### Wyndham San Diego Bayside

6/10 Okay

"The hotel is pretty run down. Our curtain was ripped, the balcony furniture was old and worn out and dirty, the bed skirts were stained. AC didn’t work first day. Overall, the property is aged and worn down. Staff were all super friendly though. "

[](https://expedia.com/San-Diego-Hotels-Wyndham-San-Diego-Bayside.h11177.Hotel-Information)

![Bahia Resort Hotel](https://images.trvl-media.com/lodging/1000000/20000/18300/18241/1b98f5a3_y.jpg)

### Bahia Resort Hotel

10/10 Excellent

"Great Place"

[](https://expedia.com/San-Diego-Hotels-Bahia-Resort-Hotel.h18241.Hotel-Information)

![DoubleTree by Hilton San Diego - Del Mar](https://images.trvl-media.com/lodging/1000000/20000/15300/15236/aa48478b_y.jpg)

### DoubleTree by Hilton San Diego - Del Mar

10/10 Excellent

"Great staff great location great room "

[](https://expedia.com/San-Diego-Hotels-DoubleTree-By-Hilton-San-Diego-Del-Mar.h15236.Hotel-Information)

![Hilton San Diego/Del Mar](https://images.trvl-media.com/lodging/1000000/30000/24900/24895/06ebc015_y.jpg)

### Hilton San Diego/Del Mar

10/10 Excellent

"Would definitely stay here again"

[](https://expedia.com/Del-Mar-Hotels-Hilton-San-Diego-Del-Mar.h24895.Hotel-Information)

![The DEXTRO Little Italy, BW Premier Collection](https://images.trvl-media.com/lodging/1000000/180000/170400/170338/6fe441dd_y.jpg)

### The DEXTRO Little Italy, BW Premier Collection

6/10 Okay

"This hotel is in a great spot downtown, but be aware parking is $35 a day, so I chose to find street parking nearby instead. There is no elevator at the top floor of parking and you will have to walk alongside where cars are driving up. The cleanliness was excellent, the floor was very clean and I appreciated that so much. Hotel staff were very friendly and informative. The only experience I was disappointed by at this hotel was the food at the restaurant. After spending 8hrs of travel time to make it there, I previously checked the restaurant menu online to avoid having to drive somewhere else for dinner the night of check-in. I saw a pizza on the menu and figured that would be good enough to fill up 2 people. When the server walked towards me with a personal-sized pizza, my sister and I just looked at each other with poker faces. My issue with that was first of all, not only the fact that it was TWENTY DOLLARS, but also the fact that the menu does not list the size of the pizza. Who in their right mind would willingly pay $20 for one personal-sized pizza???? If I had known it was going to be that small, I absolutely would not have ordered it in the first place. I ended up having to order food over DoorDash, because 2 small slices of thin pizza were nothing for 2 hungry adults! Overall, I would stay here again for the convenience and service but I would not eat at the restaurant. "

[](https://expedia.com/San-Diego-Hotels-Four-Points-By-Sheraton-San-Diego-Downtown-Little-Italy.h170338.Hotel-Information)

![Sheraton San Diego Resort](https://images.trvl-media.com/lodging/1000000/20000/11200/11109/w4000h2662x0y0-91d299a1_y.jpg)

### Sheraton San Diego Resort

6/10 Okay

"This hotel was absolutely breathtaking, upon checking in I had thee best service from the front desk clerks. When walking into our room we noticed the showers had mildew in the corners, and our balcony was not clean. I walked to the front desk and the girls were so helpful and got us into a new room. The new room was bit cleaner but still not what I expected from a 4 star Sheraton. The second room also had mildew around showers, behind the bed where the headboard rest was filthy and filled with dust. Although my stay here was enjoyable and delightful, I think the housekeeping needs to be reviewed. "

[](https://expedia.com/San-Diego-Hotels-Sheraton-San-Diego-Resort.h11109.Hotel-Information)

## Find out more about Santee

**Everything you need to know about Santee vacation rentals**

Whether you’re excited for the perfect family vacation, a romantic getaway for two, or the ultimate city break, we’ve got the Santee vacation rental for you. At Expedia, you can take your pick from private vacation homes, apartments, condos, resorts, cabins, villas, motels. The list goes on, and on …and on.

There’s just as wide a choice of amenities, too. Maybe you’re dreaming of your own pool, long evenings in a hot tub, or watching the kids laugh through the day at a waterpark. Maybe you just want a quiet retreat in a pet-friendly apartment. Well, we can help you find it. Hunt out the perfect Santee vacation rental for you by simply entering your desired dates. Then check your favorite filters to narrow down your search.

**Santee vacation rentals: An excellent choice for every season**

Whenever you want to travel, a warm welcome awaits you in Santee. If you’re looking for a little peace, consider booking during the quieter low season months. For more hustle and bustle, you may prefer to visit Santee in high season.

Prices vary throughout the year. Your chosen location, property type, and amenities will impact the cost of your trip, too. The selection of properties we have chosen for you start as low as $109 per night. Rates vary depending on your travel dates, location, and amenities so make a search and you might find even better deals!

**How to find incredible deals on Santee rentals**

At Expedia, we put the best Santee vacation rentals in one place. All you need to do is take your pick. And as we offer book now, pay later options, as well as free cancellation on some properties, you can plan your trip with total peace of mind. You’ll always find a great deal with Expedia.

To find some top Santee rental deals, enter your travel dates, and sort your search results by price. You can also filter by budget, so you only see accommodation in your ballpark. Next, add any filters you want—and just like that, you’ve built your dream Santee vacation.

If you’re looking for a little inspiration, browse our latest incredible offers, or use the map to view all accommodation in and around Santee. And to unlock even more fantastic deals, bundle your accommodation, flights, and car rental together to save and book with Expedia in complete confidence.

## Explore a world of travel with Expedia

- Trending destinations on Expedia.com
- All accommodation types in Santee

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- [Siesta Key Vacation Rentals ](https://www.expedia.com/Siesta-Key-Vacation-Rentals.d6881.Travel-Guide-VacationRentals)
- [Galveston Vacation Rentals ](https://www.expedia.com/Galveston-Vacation-Rentals.d1341.Travel-Guide-VacationRentals)
- [Clearwater Beach Vacation Rentals ](https://www.expedia.com/Clearwater-Beach-Vacation-Rentals.d10759.Travel-Guide-VacationRentals)
- [Palm Springs Vacation Rentals ](https://www.expedia.com/Palm-Springs-Vacation-Rentals.d180676.Travel-Guide-VacationRentals)
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- [Florida Vacation Rentals ](https://www.expedia.com/Destinations-In-Florida.d211.Vacation-Rental-Destinations)
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- [Michigan Vacation Rentals ](https://www.expedia.com/Destinations-In-Michigan.d224.Vacation-Rental-Destinations)

- [Vacation Homes in Santee ](https://expedia.com/Santee-Private-Vacation-Homes.d6678-aaPrivateVacationHomes.Travel-Guide-Accommodation)
- [Apartments in Santee ](https://expedia.com/Santee-Apartments.d6678-aaApartments.Travel-Guide-Accommodation)
- [Condo Rentals in Santee ](https://expedia.com/Santee-Condos.d6678-aaCondos.Travel-Guide-Accommodation)
- [Cottages in Santee ](https://expedia.com/Santee-Cottages.d6678-aaCottages.Travel-Guide-Accommodation)
- [Villas in Santee ](https://expedia.com/Santee-Villas.d6678-aaVillas.Travel-Guide-Accommodation)
- [Guest Houses in Santee ](https://expedia.com/Santee-Guest-Houses.d6678-aaGuestHouses.Travel-Guide-Accommodation)
- [Resorts in Santee ](https://expedia.com/Santee-Resorts.d6678-aaResorts.Travel-Guide-Accommodation)
- [Motels in Santee ](https://expedia.com/Santee-Motels.d6678-aaMotels.Travel-Guide-Accommodation)
- [Aparthotels in Santee ](https://expedia.com/Santee-Apart-Hotels.d6678-aaApartHotels.Travel-Guide-Accommodation)
- [Hostels in Santee ](https://expedia.com/Santee-Hostels.d6678-aaHostels.Travel-Guide-Accommodation)
- [Cabin Rentals in Santee ](https://expedia.com/Santee-Cabins.d6678-aaCabins.Travel-Guide-Accommodation)
- [B&B in Santee ](https://expedia.com/Santee-Bed-And-Breakfast.d6678-aaBedAndBreakfast.Travel-Guide-Accommodation)
- [Farmstay in Santee ](https://expedia.com/Santee-Agritourism.d6678-aaAgritourism.Travel-Guide-Accommodation)
- [Lodges in Santee ](https://expedia.com/Santee-Lodges.d6678-aaLodges.Travel-Guide-Accommodation)
- [RV Parks in Santee ](https://expedia.com/Santee-RV-Parks.d6678-aaRVParks.Travel-Guide-Accommodation)
- [Houseboats in Santee ](https://expedia.com/Santee-Houseboats.d6678-aaHouseboats.Travel-Guide-Accommodation)
- [Inns in Santee ](https://expedia.com/Santee-Inns.d6678-aaInns.Travel-Guide-Accommodation)
- [Ranches in Santee ](https://expedia.com/Santee-Ranches.d6678-aaRanches.Travel-Guide-Accommodation)
- [Residences in Santee ](https://expedia.com/Santee-Residences.d6678-aaResidences.Travel-Guide-Accommodation)
- [Castles in Santee ](https://expedia.com/Santee-Castles.d6678-aaCastles.Travel-Guide-Accommodation)

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