Santee Vacation Rentals

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Our top choices for Santee vacation rentals

Aparthotel in Downtown San Diego

Sentral Gaslamp Quarter
4.0 star property
9.2 out of 10, Wonderful, (607)
"Everything was splendid. Very friendly staff as well. "
United States
Irving
$135 nightly
The price is $156
Jan 3 - Jan 4, 2026
Total with taxes and fees
Sentral Gaslamp Quarter

Condo in Historic Downtown Coronado

Coronado Beach Resort
3.0 star property
9.0 out of 10, Wonderful, (753)
"This stay was one of our best yet! Highly recommend! Friendly staff. Great space"
United States
Sheree
$199 nightly
The price is $219
Jan 4 - Jan 5, 2026
Total with taxes and fees
Coronado Beach Resort

Condo in San Diego Country Estates

San Diego Country Estates
2.5 star property
9.4 out of 10, Exceptional, (244)
"The staff was amazing, the suite super clean and quiet place to relax"
United States
Javier
$117 nightly
The price is $124
Jan 1 - Jan 2, 2026
Total with taxes and fees
San Diego Country Estates
8.8 out of 10, Excellent, (30)
"The house was very clean and the neighborhood is pretty quiet. Great for vacation stay."
United States
AJ M.
$203 nightly
The price is $226
Dec 29 - Dec 30
Total with taxes and fees
'Ted' 2-bedroom cozy house in central location! 10 minutes to Balboa!
10.0 out of 10, Exceptional, (4)
"Great location. Great owners "
United States
INGRID R.
$160 nightly
The price is $174
Jan 8 - Jan 9, 2026
Total with taxes and fees
Terrific studio in Chula Vista with cozy vibes
9.6 out of 10, Exceptional, (28)
"Loved this property. Pool and outside patio area with kitchen was great! The view from the cabin was wonderful under the stars at night and beautiful to wake up to."
United States
Leslie F.
$196 nightly
The price is $196
Jan 4 - Jan 5, 2026
Total with taxes and fees
Hilltop cabin with panoramic lake & mountain views
4.5 star property
9.6 out of 10, Exceptional, (108)
"would definitely go back and stay there again "
United States
Kounwick
$113 nightly
The price is $128
Dec 29 - Dec 30
Total with taxes and fees
City24 Hotel Little Italy Mission Hills
9.6 out of 10, Exceptional, (54)
"Second stay and we’ll be back !! Good location, owner easy to work with, clean & tidy !!"
United States
Kevin O.
$264 nightly
The price is $294
Jan 2 - Jan 3, 2026
Total with taxes and fees
Cozy Pacific Beach Cottage w/Bikes, Private Yard & Entrance
2.0 star property
9.8 out of 10, Exceptional, (12)
"Great location and accommodations."
United States
Kecia
$260 nightly
The price is $289
Dec 27 - Dec 28
Total with taxes and fees
NEW Peaceful Studio Unit - 3 Blocks from the beach

Condo in Del Mar

Wave Crest Resort
3.0 star property
9.2 out of 10, Wonderful, (144)
"Great location "
United States
Erin
$240 nightly
The price is $266
Jan 5 - Jan 6, 2026
Total with taxes and fees
Wave Crest Resort
9.8 out of 10, Exceptional, (191)
"Nice stay next to beach, restaurants, and shops."
United States
Kristine R.
$297 nightly
The price is $323
Jan 10 - Jan 11, 2026
Total with taxes and fees
Charming, Elegant, Luxury, Walk to Moonlight Beach & Downtown
10.0 out of 10, Exceptional, (1)
"Location, good building, lovely host."
United Kingdom
Clarice P.
$153 nightly
The price is $170
Jan 4 - Jan 5, 2026
Total with taxes and fees
Spacious peacefull studio w/free parking, hot tub, gym. Near Balboa Park.
9.8 out of 10, Exceptional, (34)
"Great experience for a short trip. "
United States
jasmine j.
$219 nightly
The price is $219
Dec 28 - Dec 29
Total with taxes and fees
Vintage Airstream Trailer in the Hills of San Marcos!

Aparthotel in Downtown San Diego

Kasa Gaslamp Quarter San Diego
3.5 star property
8.0 out of 10, Very Good, (154)
"Everything was perfect about the room and location. The minor flaw was the stench in the lobby from the downstairs restaurant and bar. I loved staying here. "
United States
Chris
$95 nightly
The price is $109
Jan 5 - Jan 6, 2026
Total with taxes and fees
Kasa Gaslamp Quarter San Diego
10.0 out of 10, Exceptional, (10)
"Gorgeous view, very responsive host. We enjoyed our stay and would recommend "
United States
Carol
$337 nightly
The price is $337
Jan 12 - Jan 13, 2026
Total with taxes and fees
Breathtaking retreat in the wine country on the ranch with goats you can pet!
10.0 out of 10, Exceptional, (12)
"Beautiful, peaceful, quiet and lovely place. We enjoyed our and able to get good sleep on their comfortable beds. It was so close to Rancho Guejito Vineyard/Wedding Venue, which was so convenient for us to close to my daughter’s wedding. Highly recommend this place. "
United States
Noemi A.
$282 nightly
The price is $301
Dec 29 - Dec 30
Total with taxes and fees
Private 2 bedroom apt in new craftsman ranch!
2.5 star property
8.4 out of 10, Very Good, (264)
"Overall good place."
United States
Isaac
$103 nightly
The price is $116
Jan 4 - Jan 5, 2026
Total with taxes and fees
Uptown Inn by Vantaggio - Limited Service Apart-Hotel
10.0 out of 10, Exceptional, (60)
"Lovely place to stay. "
United States
Brielle P.
$314 nightly
The price is $347
Jan 13 - Jan 14, 2026
Total with taxes and fees
Luxurious La Costa Remodel by SPA w/Steam Shower and Washer/Dryer!
10.0 out of 10, Exceptional, (268)
"We enjoyed our stay. The place was perfect and there was even a dog bed, toys, and a water dish filled with water waiting for us when we got there. Within walking distance to lots of dog friendly restaurants and within a 10-15min drive to all the things we wanted to do in San Diego, including an off leash dog beach. Would stay here again."
United States
Michele S.
$217 nightly
The price is $241
Jan 18 - Jan 19, 2026
Total with taxes and fees
Adorable 1 bd cottage, heart of Old Town-- WE LOVE PETS! Insta @oldtownvacay
3.0 star property
$511 nightly
The price is $549
Jan 4 - Jan 5, 2026
Total with taxes and fees
San Diego Home: AC, Hot Tub, Covered Patio & BBQ
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Santee Hotel Reviews

Find out more about Santee

Everything you need to know about Santee vacation rentals

Whether you’re excited for the perfect family vacation, a romantic getaway for two, or the ultimate city break, we’ve got the Santee vacation rental for you. At Expedia, you can take your pick from private vacation homes, apartments, condos, resorts, cabins, villas, motels. The list goes on, and on …and on.

There’s just as wide a choice of amenities, too. Maybe you’re dreaming of your own pool, long evenings in a hot tub, or watching the kids laugh through the day at a waterpark. Maybe you just want a quiet retreat in a pet-friendly apartment. Well, we can help you find it. Hunt out the perfect Santee vacation rental for you by simply entering your desired dates. Then check your favorite filters to narrow down your search.

Santee vacation rentals: An excellent choice for every season

Whenever you want to travel, a warm welcome awaits you in Santee. If you’re looking for a little peace, consider booking during the quieter low season months. For more hustle and bustle, you may prefer to visit Santee in high season.

Prices vary throughout the year. Your chosen location, property type, and amenities will impact the cost of your trip, too. The selection of properties we have chosen for you start as low as $109 per night. Rates vary depending on your travel dates, location, and amenities so make a search and you might find even better deals!

How to find incredible deals on Santee rentals

At Expedia, we put the best Santee vacation rentals in one place. All you need to do is take your pick. And as we offer book now, pay later options, as well as free cancellation on some properties, you can plan your trip with total peace of mind. You’ll always find a great deal with Expedia.

To find some top Santee rental deals, enter your travel dates, and sort your search results by price. You can also filter by budget, so you only see accommodation in your ballpark. Next, add any filters you want—and just like that, you’ve built your dream Santee vacation.

If you’re looking for a little inspiration, browse our latest incredible offers, or use the map to view all accommodation in and around Santee. And to unlock even more fantastic deals, bundle your accommodation, flights, and car rental together to save and book with Expedia in complete confidence.

Frequently asked questions

Can I find a vacation rental in Santee?

Yes, there are vacation rentals where you'll be just 12.5 mi (20.1 km) from San Diego Zoo, giving you a more secluded option if you want a quieter place to stay. The shops and restaurants are several reasons why visitors like Santee. While you're here, grab a bite or have a drink at the bars.

What are some of the best vacation home rentals in Santee?

Oceanfront Beach, Pool, Hot Tub, Pickleball, Movie Theater, Elevator & Golf Cart: Visitors like this Santee vacation home rental. It is located on the beach and has an outdoor pool, a fireplace, and a barbecue grill to put you at ease in your new surroundings. It has 8 bedrooms as well as a kitchen with a dishwasher, a fridge, and a stovetop, so you can cook with friends or family. It offers a balcony, a garden, and a selection of games so you can immerse yourself in your vacation.

How many vacation rentals are there in Santee?

Expedia has 8 vacation rentals for your stay in Santee.

What’s there to see and do in Santee?

Cultural attractions include Off Broadway Live and Creation and Earth History Museum, whereas Mission Trails Regional Park and Sportsplex USA Santee are a couple of picturesque spots to enjoy the outdoors. San Diego Zoo and Petco Park are other popular places to visit in the area.

What are vacation rentals like in Santee?

Vacation rentals are private accommodations you can stay in for several days or longer in Santee. Vacation rentals feature extras such as WiFi and washers and dryers so you'll be comfy for your stay. If you're concerned about cleanliness, a vacation rental can offer a sense of security away from shared hotel elevators and lobbies bustling with people while still allowing you to travel. You'll also have more space in a vacation rental than in a traditional hotel, which makes a vacation rental a popular choice for families.