Panoramic view from Mesa Trail overlooking Santee, with dry hills and distant mountains under a clear sky

Santee Vacation Rentals

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Our top choices for Santee vacation rentals

Marriott Vacation Club®, San Diego

Marriott Vacation Club®, San Diego
3.5 star property
Downtown San Diego
9.4 out of 10, Exceptional, (1,120 reviews)
"Great stay! Big room, comfortable"
United States
Christine
$186 nightly
The price is $216
Jul 20 - Jul 21
Total with taxes and fees
Marriott Vacation Club®, San Diego

Coronado Beach Resort

Coronado Beach Resort
3.0 star property
Historic Downtown Coronado
9.0 out of 10, Wonderful, (799 reviews)
"Great stay"
United States
Vjosa
$389 nightly
The price is $428
Jul 15 - Jul 16
Total with taxes and fees
Coronado Beach Resort

City24 Hotel Little Italy Mission Hills

City24 Hotel Little Italy Mission Hills
4.5 star property
Middletown
9.8 out of 10, Exceptional, (166 reviews)
"Nice and very friendly staff was a great stay"
United States
Alexander
$186 nightly
The price is $210
Jun 28 - Jun 29
Total with taxes and fees
City24 Hotel Little Italy Mission Hills

Yard & Grill! Cottage Near Balboa Park & Comic-con

Yard & Grill! Cottage Near Balboa Park & Comic-con
3.0 star property
South Park
$452 nightly
The price is $506
Jul 1 - Jul 2
Total with taxes and fees
Yard & Grill! Cottage Near Balboa Park & Comic-con

Hilltop cabin with panoramic lake & mountain views

Hilltop cabin with panoramic lake & mountain views
Del Dios
9.6 out of 10, Exceptional, (39 reviews)
"I loved how unique and cute this stay was"
United States
Kayla
$196 nightly
The price is $196
Jul 1 - Jul 2
Total with taxes and fees
Hilltop cabin with panoramic lake & mountain views

Beautiful Normal Heights Living

Beautiful Normal Heights Living
Mid-City
10.0 out of 10, Exceptional, (96 reviews)
"Amazing stay overall!"
United States
Imany G.
$286 nightly
The price is $318
Jun 28 - Jun 29
Total with taxes and fees
Beautiful Normal Heights Living

Adorable 1 bedroom house 8 min from La Jolla!

Adorable 1 bedroom house 8 min from La Jolla!
Bay Ho
10.0 out of 10, Exceptional, (54 reviews)
"Everything was in great shape."
United States
emma c.
$262 nightly
The price is $291
Jul 1 - Jul 2
Total with taxes and fees
Adorable 1 bedroom house 8 min from La Jolla!

Cozy Pacific Beach Cottage w/Bikes, Private Yard & Entrance

Cozy Pacific Beach Cottage w/Bikes, Private Yard & Entrance
Pacific Beach
9.6 out of 10, Exceptional, (54 reviews)
"Second stay and we’ll be back !! Good location, owner easy to work with, clean & tidy !!"
United States
Kevin O.
$313 nightly
The price is $348
Jul 12 - Jul 13
Total with taxes and fees
Cozy Pacific Beach Cottage w/Bikes, Private Yard & Entrance

Bright and spacious home with views, pool & spa.

Bright and spacious home with views, pool & spa.
San Carlos
9.4 out of 10, Exceptional, (30 reviews)
"Everything was as advertised, I would recommend staying here."
United States
Scott S.
$815 nightly
The price is $869
Jun 28 - Jun 29
Total with taxes and fees
Bright and spacious home with views, pool & spa.

Luxury Private Oasis- 2 King Suites - Pool-Spa-Fire Pit-Sauna-Arcades-Playground

Luxury Private Oasis- 2 King Suites - Pool-Spa-Fire Pit-Sauna-Arcades-Playground
Mount Helix
10.0 out of 10, Exceptional, (35 reviews)
"Fully stocked house, great commutation "
United States
Jim F.
$1,685 nightly
The price is $1,840
Jul 1 - Jul 2
Total with taxes and fees
Luxury Private Oasis- 2 King Suites - Pool-Spa-Fire Pit-Sauna-Arcades-Playground

Private Cozy Clean, close to EVERYTHING

Private Cozy Clean, close to EVERYTHING
Mid-City
9.8 out of 10, Exceptional, (67 reviews)
"Everything was great, convenient location to everything. "
United States
Terri J.
$456 nightly
The price is $508
Jul 26 - Jul 27
Total with taxes and fees
Private Cozy Clean, close to EVERYTHING

Luxe 2BR La Jolla Escape Near the Beach & Jacuzzi

Luxe 2BR La Jolla Escape Near the Beach & Jacuzzi
Beach Barber Tract
9.8 out of 10, Exceptional, (17 reviews)
"Can’t beat the location! Property felt “new” - almost like we were the first to stay there. Good communication from property manager. Would return the next time we visit San Diego."
United States
Kevin
$647 nightly
The price is $647
Jun 29 - Jun 30
Total with taxes and fees
Luxe 2BR La Jolla Escape Near the Beach & Jacuzzi

Stylish South Park Home | Near Zoo, Downtown & Dining

Stylish South Park Home | Near Zoo, Downtown & Dining
Mid-City
10.0 out of 10, Exceptional, (15 reviews)
"Wonderful spot to stay. Perfect distance from popular San Diego attractions, and the interior was tidy and comfortable."
United States
Aidan N.
$759 nightly
The price is $841
Jun 28 - Jun 29
Total with taxes and fees
Stylish South Park Home | Near Zoo, Downtown & Dining

Near Pacific Beach, Comic-con! Sunny San Diego Gem

Near Pacific Beach, Comic-con! Sunny San Diego Gem
3.0 star property
Pacific Beach
10.0 out of 10, Exceptional, (2 reviews)
"Strategic location for beach, amusement parks and restaurants. Close to major freeways and airport. House has plenty of room across the three floors. Kids loved seeing the seaworld fireworks from the open air rooftop patio. This property has it all. Owner quickly addressed any of our questions and needs. "
United States
Thomas
$934 nightly
The price is $1,050
Jul 2 - Jul 3
Total with taxes and fees
Near Pacific Beach, Comic-con! Sunny San Diego Gem

Family Friendly Modern Guest House

Family Friendly Modern Guest House
Mira Mesa
10.0 out of 10, Exceptional, (16 reviews)
"Very nice and comfortable home. June was very attentive and quick to respond to any questions. "
United States
Nancy M.
$554 nightly
The price is $616
Jul 13 - Jul 14
Total with taxes and fees
Family Friendly Modern Guest House

Ocean Beach Pier Condo

Ocean Beach Pier Condo
Ocean Beach
9.8 out of 10, Exceptional, (64 reviews)
"Really like the place and so did my family!! Great location!! Would recommend this place!! "
United States
Brittany B.
$573 nightly
The price is $639
Jul 20 - Jul 21
Total with taxes and fees
Ocean Beach Pier Condo

Perfect Location to Beach/SD Attractions, Parking, Beach Chairs, Boogie Boards!

Perfect Location to Beach/SD Attractions, Parking, Beach Chairs, Boogie Boards!
Ocean Beach
10.0 out of 10, Exceptional, (273 reviews)
"Great location, very clean. Easy beach access. It was perfect for our family. Very relaxing. We appreciated the beach accessories. "
United States
Jenny R.
$508 nightly
The price is $564
Jun 29 - Jun 30
Total with taxes and fees
Perfect Location to Beach/SD Attractions, Parking, Beach Chairs, Boogie Boards!

San Diego’s Luxury Mountain Cabin Retreat

San Diego’s Luxury Mountain Cabin Retreat
El Cajon
9.8 out of 10, Exceptional, (22 reviews)
"We had a wonderful stay! The house was great and exactly as shown in the listing—the pictures and description were 100% accurate. Communication with the host was excellent; they were very responsive and helpful throughout the entire process. Highly recommend this property!"
United States
Claudia M.
$933 nightly
The price is $972
Jul 11 - Jul 12
Total with taxes and fees
San Diego’s Luxury Mountain Cabin Retreat

Near Pacific Beach, Comic-Con! Sunny San Diego Gem

Near Pacific Beach, Comic-Con! Sunny San Diego Gem
Pacific Beach
9.6 out of 10, Exceptional, (63 reviews)
"Love the rooftop patioGreat location Always clean and comfortable "
United States
Rene O.
$922 nightly
The price is $1,025
Jul 2 - Jul 3
Total with taxes and fees
Near Pacific Beach, Comic-Con! Sunny San Diego Gem

La Mesa Family Retreat - 20 minutes to Beaches & More!

La Mesa Family Retreat - 20 minutes to Beaches & More!
La Mesa
9.0 out of 10, Wonderful, (7 reviews)
"The property was well located for us. "
United States
Ann D.
$723 nightly
The price is $723
Jul 6 - Jul 7
Total with taxes and fees
La Mesa Family Retreat - 20 minutes to Beaches & More!
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Santee Hotel Reviews

Find out more about Santee

Everything you need to know about Santee vacation rentals

Whether you’re excited for the perfect family vacation, a romantic getaway for two, or the ultimate city break, we’ve got the Santee vacation rental for you. At Expedia, you can take your pick from private vacation homes, apartments, condos, resorts, cabins, villas, motels. The list goes on, and on …and on.

There’s just as wide a choice of amenities, too. Maybe you’re dreaming of your own pool, long evenings in a hot tub, or watching the kids laugh through the day at a waterpark. Maybe you just want a quiet retreat in a pet-friendly apartment. Well, we can help you find it. Hunt out the perfect Santee vacation rental for you by simply entering your desired dates. Then check your favorite filters to narrow down your search.

Santee vacation rentals: An excellent choice for every season

Whenever you want to travel, a warm welcome awaits you in Santee. If you’re looking for a little peace, consider booking during the quieter low season months. For more hustle and bustle, you may prefer to visit Santee in high season.

Prices vary throughout the year. Your chosen location, property type, and amenities will impact the cost of your trip, too. The selection of properties we have chosen for you start as low as $119 per night. Rates vary depending on your travel dates, location, and amenities so make a search and you might find even better deals!

How to find incredible deals on Santee rentals

At Expedia, we put the best Santee vacation rentals in one place. All you need to do is take your pick. And as we offer book now, pay later options, as well as free cancellation on some properties, you can plan your trip with total peace of mind. You’ll always find a great deal with Expedia.

To find some top Santee rental deals, enter your travel dates, and sort your search results by price. You can also filter by budget, so you only see accommodation in your ballpark. Next, add any filters you want—and just like that, you’ve built your dream Santee vacation.

If you’re looking for a little inspiration, browse our latest incredible offers, or use the map to view all accommodation in and around Santee. And to unlock even more fantastic deals, bundle your accommodation, flights, and car rental together to save and book with Expedia in complete confidence.

Explore a world of travel with Expedia

Frequently asked questions

Can I find a vacation rental in Santee?

Yes, there are vacation rentals where you'll be just 12.5 mi (20.1 km) from San Diego Zoo, giving you a more secluded option if you want a quieter place to stay. The shops and restaurants are several reasons why visitors like Santee. While you're here, grab a bite or have a drink at the bars.

What are some of the best vacation home rentals in Santee?

3 Story Spanish Style House, Best Location in SD. Views of North Park, With AC: You might want to consider this vacation rental near Santee, which is equipped with a barbecue grill, air-conditioning, and laundry facilities to help you feel comfortable during your stay. It has 4 bedrooms as well as a kitchen with a dishwasher, a fridge, and a stovetop, so you can cook with friends or family.

How many vacation rentals are there in Santee?

Expedia has 6 vacation rentals for your stay in Santee.

What’s there to see and do in Santee?

Cultural attractions include Off Broadway Live and Creation and Earth History Museum, whereas Sportsplex USA Santee and Santee Lakes are a couple of picturesque spots to enjoy the outdoors. San Diego Zoo and Petco Park are other popular places to visit in the area.

What are vacation rentals like in Santee?

Vacation rentals are private accommodations you can stay in for several days or longer in Santee. Vacation rentals feature extras such as WiFi and washers and dryers so you'll be comfy for your stay. If you're concerned about cleanliness, a vacation rental can offer a sense of security away from shared hotel elevators and lobbies bustling with people while still allowing you to travel. You'll also have more space in a vacation rental than in a traditional hotel, which makes a vacation rental a popular choice for families.